Journal of Chest Surgery
- Volume 13 Issue 4
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- Pages.338-345
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- 1980
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- 2765-1606(pISSN)
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- 2765-1614(eISSN)
Perfusion Techniques Using the Modified Isolated Working Rat Heart Model
흰쥐의 심장을 이용한 Modified Isolated Working Heart Perfusion Technique
- Lee, Chong-Kook (Dept.of Thoracic and Cardiovascular Surgery, Collere of Medicine, Chosun University) ;
- Choi, Hyeong-Ho
- Published : 1980.12.01
Abstract
We have modified an isolated perfusion rat heart model of cardiopulmonary bypass, with which we are able to screen the effects of various cardioplegic solutions and hypothermia upon the ability of the heart to survivie during and recover from period of ischemic arrest. The modified experimental model was differed from the original as follow : a heat coil chamber of atrial and aortic reservoir provided temperature control, and the perfusate was gassed with each pure oxygen and pure carbon dioxide in 95:5 ratio. The Langendorff perfusion was initiated for a 10 minute period by introducing perfusate at
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