• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2022.11a
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• pp.141-144
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• 2022

최근 인터넷을 통한 동영상 제공 서비스가 확대됨에 따라 높은 품질의 온라인 컨텐츠에 대한 수요가 급증하고 있다. 그런데 넓은 동적 범위를 표현할 수 있는 High Dynamic Range (HDR) 컨텐츠의 공급은 수요를 따라가지 못하고 있는 실정이다. 본 논문에서는 밝기가 다른 프레임들로 구성된 Low Dynamic Range (LDR) 동영상을 이용해 HDR 영상을 생성하는 방법을 제안한다. 우선, 프레임들 간에 움직임이 존재하기 때문에 정렬 과정을 통해 이웃 프레임들을 중심 프레임에 맞추어 정렬한다. 이때 내용 (content) 기반으로 정렬을 해 정확도를 높이고, 원래 크기의 입력을 그대로 이용하는 모듈을 함께 사용하여 세부 정보도 잘 살려준다. 그리고 나서 잘 정렬된 다중 프레임들을 합쳐서 하나의 HDR 프레임을 생성한다. 실험을 통해 기존 방법들에 비해 우수한 성능을 보임을 확인하였다.

• BMB Reports
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• v.51 no.9
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• pp.437-443
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• 2018

Non-homologous end joining (NHEJ), and to a lesser extent, the error-free pathway known as homology-directed repair (HDR) are cellular mechanisms for recovery from double-strand DNA breaks (DSB) induced by RNA-guided programmable nuclease CRISPR/Cas. Since NHEJ is equivalent to using a duck tape to stick two pieces of metals together, the outcome of this repair mechanism is prone to error. Any out-of-frame mutations or premature stop codons resulting from NHEJ repair mechanism are extremely handy for loss-of-function studies. Substitution of a mutation on the genome with the correct exogenous repair DNA requires coordination via an error-free HDR, for targeted transgenesis. However, several practical limitations exist in harnessing the potential of HDR to replace a faulty mutation for therapeutic purposes in all cell types and more so in somatic cells. In germ cells after the DSB, copying occurs from the homologous chromosome, which increases the chances of incorporation of exogenous DNA with some degree of homology into the genome compared with somatic cells where copying from the identical sister chromatid is always preferred. This review summarizes several strategies that have been implemented to increase the frequency of HDR with a focus on somatic cells. It also highlights the limitations of this technology in gene therapy and suggests specific solutions to circumvent those barriers.

• Journal of Advanced Navigation Technology
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• v.9 no.2
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• pp.140-146
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• 2005

In this paper, we proposed the frequency offset compensation algorithm and tracking algorithm which could improve the accumulated phase error for HDR-WPAN system. The proposed frequency offset compensation technique estimated each sample phase error by autocorrelation characteristics of CAZAC sequence, estimated phase error multiple each sample in a symbol, and finally compensated for the frequency offset. After frequency offset compensation using two steps, coarse and fine frequency offset, tracking algorithm have to use to compensate for the accumulated phase error. Because there is no pilot symbol in payload, more phase rotation occurred in received signal constellations due to the accumulated phase error as the payload length increase. Tracking algorithm compensates for a cumulative phase error ${\theta}$ between payload data.

• Progress in Medical Physics
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• v.14 no.1
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• pp.15-19
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• 2003

High dose rate (HDR) brachytherapy for treating a cervix carcinoma has become popular, because it eliminates many of the problems associated with conventional brachytherapy. In order to improve the clinical effectiveness with HDR brachytherapy, a dose calculation algorithm, optimization procedures, and image registrations need to be verified by comparing the dose distributions from a planning computer and those from a phantom. In this study, the phantom was fabricated in order to verify the absolute doses and the relative dose distributions. The measured doses from the phantom were then compared with the treatment planning system for the dose verification. The phantom needs to be designed such that the dose distributions can be quantitatively evaluated by utilizing the dosimeters with a high spatial resolution. Therefore, the small size of the thermoluminescent dosimeter (TLD) chips with a dimension of <1/8"and film dosimetry with a spatial resolution of <1mm used to measure the radiation dosages in the phantom. The phantom called a pelvic phantom was made from water and the tissue-equivalent acrylic plates. In order to firmly hold the HDR applicators in the water phantom, the applicators were inserted into the grooves of the applicator holder. The dose distributions around the applicators, such as Point A and B, were measured by placing a series of TLD chips (TLD-to-TLD distance: 5mm) in the three TLD holders, and placing three verification films in the orthogonal planes. This study used a Nucletron Plato treatment planning system and a Microselectron Ir-192 source unit. The results showed good agreement between the treatment plan and measurement. The comparisons of the absolute dose showed agreement within $\pm$4.0 % of the dose at point A and B, and the bladder and rectum point. In addition, the relative dose distributions by film dosimetry and those calculated by the planning computer show good agreement. This pelvic phantom could be a useful to verify the dose calculation algorithm and the accuracy of the image localization algorithm in the high dose rate (HDR) planning computer. The dose verification with film dosimetry and TLD as quality assurance (QA) tools are currently being undertaken in the Catholic University, Seoul, Korea.

• BMB Reports
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• v.41 no.2
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• pp.112-118
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• 2008

Camptothecin is an anti-cancer monoterpene indole alkaloid. The gene encoding 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (designated as CaHDR), the last catalytic enzyme of the MEP pathway for terpenoid biosynthesis, was isolated from camptothecin-producing Camptotheca acuminata. The full-length cDNA of CaHDR was 1686 bp encoding 459 amino acids. Comparison of the cDNA and genomic DNA of CaHDR revealed that there was no intron in genomic CaHDR. Southern blot analysis indicated that CaHDR belonged to a low-copy gene family. RT-PCR analysis revealed that CaHDR expressed constitutively in all tested plant organs with the highest expression level in flowers, and the expression of CaHDR could be induced by 100 ${\mu}M$ methyl-jasmonate (MeJA), but not by 100 mg/L salicylic acid (SA) in the callus of C. acuminata. The complementation of CaHDR in Escherichia coli ispH mutant MG1655 demonstrated its function.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38A no.11
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• pp.919-927
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• 2013

In this paper, we present a perception-based tone mapping technique using histogram modification for displaying high dynamic range image. HDR (high dynamic range) tone mapping algorithms are used to display HDR image on LDR (low dynamic rnage) devices. Although perception-based tone mapping methods provides better performance, it dose not always produce good results for a wide variety of images. The proposed method reduces dynamic range by using the perception-based tone mapping function and histogram modification. A derivative of perception-based tone mapping function is used as constraint function of histogram and additional compensation process is performed. This method not only improves contrast by adopting different constraints on each pixel value, but also preserves more visual details. In order to prevent over enhancement, histogram modification technique is applied. Furthermore, it can control the rate of image contrast using control parameters. Subjective and objective evaluations show that proposed algorithm is better than existing algorithms.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.1
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• pp.788-791
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• 2005

In this paper, We propose performance of improvement method for eHDR-WPAN system using Interleaver. Burst error pattern caused by fading in indoor wireless channel. for the reason, using of Interleave method (make burst error to random error) can be enhance to error-rate in system. This paper is used Convolutional, Block, Random Interleaver. We make use of 9 and 27 for symbol spacing. Block-Interleaver is show that performance about 0.6dB of E$_b$/N$_o$ at $10^{-4}$. In result, the suitable Interleaver for eHDR-WPAN system is Block Interleaver of 9 symbol spacing.

• Structural Engineering and Mechanics
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• v.55 no.6
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• pp.1261-1278
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• 2015

Due to their low intrinsic damping, stay cables in cable-stayed bridges have often exhibited unanticipated and excessive vibrations which result in increasing maintenance frequency and disruption to normal operations of the entire bridges. Mitigation of undesired cable vibration can be achieved by attaching an external damping device near the anchorage. High Damping Rubber (HDR) dampers have many advantages such as compact size, better aesthetics, easy maintenance, temperature stability, and cost benefits; therefore, they have been widely used to increase cable damping. Although a single damper has been shown to reduce cable vibrations, it is not the most effective method due to geometric constraints. This paper proposes the use of two HDR dampers to improve effectiveness and robustness in suppressing cable vibration. Oscillation parameters of the cable-dampers system were investigated in detail by modeling the stay cable as a taut string and each HDR damper as complex-valued impedance and by using an analytical formulation of the complex eigenvalue problem. The problem of two HDR dampers arbitrarily located along a cable is solved and the solution is discussed. Asymptotic formulas to calculate the damping ratios of the cable with two HDR dampers installed near the anchorage(s) are proposed and compared with the exact solutions. Further, a design example is presented in order to justify the methodology. The results of this study show that when the two HDR dampers are installed close to each other on the same end of the cable, some interaction between the dampers leads to reduced damping ratio. When the dampers are on the opposite ends of the cable, they are effective in increasing damping ratio and can provide better vibration reduction to multiple modes.

• Journal of Broadcast Engineering
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• v.24 no.2
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• pp.217-226
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• 2019

In this paper, we propose a filtering method that can improve the results of inverse tone-mapping using guided image filter. Inverse tone-mapping techniques have been proposed that convert LDR images to HDR. Recently, many algorithms have been studied to convert single LDR images into HDR images using CNN. Among them, there exists an algorithm for restoring pixel information using CNN which learned to restore saturated region. The algorithm does not suppress the noise in the non-saturation region and cannot restore the detail in the saturated region. The proposed algorithm suppresses the noise in the non-saturated region and restores the detail of the saturated region using a WGIF in the input image, and then applies it to the CNN to improve the quality of the final image. The proposed algorithm shows a higher quantitative image quality index than the existing algorithms when the HDR quantitative image quality index was measured.

• Journal of the Korea Computer Graphics Society
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• v.27 no.3
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• pp.31-42
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• 2021

We propose a deep learning-based method that can estimate an appropriate lighting of both indoor and outdoor images. The method consists of two networks: Crop-to-PanoLDR network and LDR-to-HDR network. The Crop-to-PanoLDR network predicts a low dynamic range (LDR) environment map from a single partially observed normal field of view image, and the LDR-to-HDR network transforms the predicted LDR image into a high dynamic range (HDR) environment map which includes the high intensity light information. The HDR environment map generated through this process is applied when rendering virtual objects in the given image. The direction of the estimated light along with ambient light illuminating the virtual object is examined to verify the effectiveness of the proposed method. For this, the results from our method are compared with those from the methods that consider either indoor images or outdoor images only. In addition, the effect of the loss function, which plays the role of classifying images into indoor or outdoor was tested and verified. Finally, a user test was conducted to compare the quality of the environment map created in this study with those created by existing research.