• Korean Journal of Agricultural Science
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• v.46 no.4
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• pp.991-997
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• 2019

This study was conducted to investigate the laying period performance of two crossbred Korean native chicken (KNC) grand parent stock (GPS) layer during 20 to 40 weeks. A total of 351 20-week-old KNC GPS were allocated in a completely randomized design to give 4 birds per each cage. The chickens were fed commercial diets [i.e., week 20 - 32, crude protein (CP) 18.0% and metabolizable energy (ME) 2,850 kcal/kg; week 32 - 40, CP 17.0% and ME 2,800 kcal/kg)] and fresh water during the whole experiment period ad libitum basis. Body weight, age of sexual maturity, egg weight, hen-day egg production (HDP) and feed conversion ratio (FCR) were measured during the experiment period (week 20 - 40). The results show no significant difference in the Body weight, age of sexual maturity, egg weight, and hen-day egg production (HDP) except for egg weight. 1B had a higher egg weight on week 36 only. We expect that the reason why most factors showed no significant difference is the lack of nutrients caused by limited feeding which follows the standard feeding system for the grand-parent stock. These results provide basic information for laying data in 2-way crossbred Korean native chickens.

• Archives of Pharmacal Research
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• v.13 no.1
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• pp.82-96
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• 1990

Ten (E)-and (Z)-isomers of 2-phenylcyclopropylamine (PCA), 1-Me PCA, 2-Me-PCA, N-Me-PCA, and N, N-diMe PCA and fifteen o-. m-, p- isomers of (E) PCA with substituents of Me, Cl, F, OMe, OH were synthesized in this laboratory and tested for the inhibition of rat brain mitochondrial MAO-A and MAO-B. The effects of substituents, their positions, and stereochemistry on the inhibition were assessed for the compounds with substituents at cyclopropyl and amino groups and QSAR analyses were performed using the potency data of ring-substituted compounds. The best correlated QSAR equations are as follows : pI$_{50}$ = 0.804 $\pi^2$-0.834 Blo-1.069 Blm + 0.334 Lp-1.709 HDp +7.897 (r = 0.945, s =0.211, F = 16.691, p = 0.000) for the inhibition of MAO-A;PI$_{50}$= 1.815$\pi$-0.825 $\pi^2$-1.203R + 0.900 Es$^2$ + 0.869 Es$^3$ + 0.796 Es$^4$-0.992 HDp + 0.562 HAo + 3.893 (r = 0.982, s =0.178, F = 23.351, p = 0.000) for the inhibition of MAO-B. Based on the potency difference between stereoisomers of cyclopropylamine-modified compounds and an QSAR cavity near para position, two hydrophobic carities interacting with Me group, a hydrophobic site near para position, and an amino group binding site and that in addition to the same two hydrophotic cavities, hydrophotic area, steric boundaries, hydrogen-acceptor site, and amino group binding site, another steric boundary near para position and a hydrogen donating site near ortho position constitute active sites of MAO-B.

• Proceedings of the Korean Information Science Society Conference
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• 2011.06a
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• pp.477-479
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• 2011

본 논문에서는 1차원 은닉 마코프 모델을 2차원으로 확장하기 위하여 노드들의 마코프 특성이 인과적인 관계를 갖는 마코프 메쉬 모델을 이용하여 완전한 2차원 HMM의 구조를 갖는 모델을 제안한다. 마코프메쉬 모델은 이웃시스템을 통하여 이전의 시점을 정의하고, 인과적인 관계를 통하여 전이확률의 계산을 가능하게 한다. 또한 영상의 최적의 분할을 위하여 계층적 디리슐레 과정을 사전분포로 두어 고정된 상태의 수가 아닌 무한의 상태 수를 갖는 2차원 HMM을 제안한다. HDP로 정의된 사전분포와 관측된 표본 자료의 정보를 갖는 우도함수를 결합한 사후분포의 베이스 추정은 깁스샘플링 알고리즘을 이용하여 계산된다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.05a
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• pp.392-394
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• 2013

최근 u-Healthcare 서비스에서 다양한 생체정보를 간편하게 측정하는 개인건강기기(PHD)와 측정된 정보를 전송하고 수집하기 위한 표준의 필요성이 제품 간의 이식성, 확장성, 상호 운영성을 보장하기 위해 크게 대두되고 있다. 개인건강기기에서 측정된 생체정보(산소포화도, 몸무게, 심전도, 혈압 등)를 ISO/IEEE 11073 기반인 Bluetooth Health Device Profile을 이용해서 스마트폰으로 실시간 모니터링 할 수 있는 시스템을 설계한다.

• Proceedings of the Korean Society Of Semiconductor Equipment Technology
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• 2006.05a
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• pp.206-210
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• 2006

본 논문에서는 HDPCVD를 이용한 실리콘 산화막 형성에서 산화막의 특성에 영향을 미치는 RF Power, Gas, 산소 등의 공정조건과 증착된 산화막의 특성을 나타내는 증착율, 균일성 및 굴절율에 관한 주효과와 교호작응을 정량적으로 규명하고, 산화막 증착에서 관심의 대상이 되는 여러가지의 반응변수를 모두 만족시키는 최적의 공정조건을 제시한다. 실험의 효율성을 높이기 위해 통계적인 실험계획법을 활용하여 실험의 회수를 줄이는 한편 반응모델링을 통하여 입력변수와 반응변수의 관계를 시각적으로 도식화 한다. 실험을 통하여 현재 사용되고 있는 공정조건에 대한 개선점을 발견하였으며, 수립된 모델을 바탕으로 한 반응최적화 알고리즘을 통하여 세 가지 반응변수 모두 만족시킬 수 있는 5가지의 입력조건을 제시한다.

• Kosin Medical Journal
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• v.33 no.3
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• pp.391-395
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• 2018

We report a case of a patient with locally advanced prostate cancer who had only lymph node involvement without bone metastasis on F-18 FDG PET/CT. A 62-year-old Korean male was admitted to our hospital due to dysuria. His PSA level on admission was 79.35 ng/mL. A transrectal ultrasound-guided prostate biopsy confirmed prostate cancer and his Gleason score was 10 (5+5). F-18 FDG PET/CT demonstrated a hypermetabolic mass lesion with SUVmax 7.0 in the prostate and hypermetabolism with SUVmax 4.7 of the abdominal and pelvic lymph nodes. Tc-99m HDP bone scan showed no significant bone metastasis. The patient underwent hormonal therapy for 9 months. Follow-up F-18 FDG PET/CT showed significantly reduced size and FDG uptake in the prostate and abdominal and pelvic lymph nodes. In this case, treatment monitoring with F-18 FDG PET/CT showed decreased mass size and FDG uptake in the prostate and abdominal and pelvic lymph nodes.

• The Korean Journal of Nuclear Medicine Technology
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• v.20 no.2
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• pp.36-41
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• 2016

Purpose Sentinel lymphoscintigraphy (SLS) was using only $^{99m}Tc-phytate$. If the supply is interrupted temporarily, there is no alternative radiopharmaceuticals. The aim of this study measure the particle size of radiopharmaceuticals and look for radiopharmaceuticals which can be substituted for $^{99m}Tc-phytate$. Materials and Methods The particle size of radiopharmaceuticals were analyzed by a nano-particle analyzer. This study were selected known radiopharmaceuticals to be useful particle size for SLS. We were divided into control and experimental groups using $^{99m}Tc-DPD$, $^{99m}Tc-MAG3$, $^{99m}Tc-DMSA$ with $^{99m}Tc-phytate$. For in-vivo experiment, radiopharmaceuticals were injected intradermally at both foot to perform lymphoscintigraphy. Imaging was acquired to dynamic and delayed static image and observe the inguinal lymph nodes with the naked eye. Results Particle size was measured respectively Phytate 105~255 nm (81.9%), MAG3 91~255 nm (98.7%), DPD 105~342 nm (77.3%), DMSA 164~ 342 nm (99.2%), MAA 1281~2305 nm (90.6%), DTPA 342~1106 nm (79.4%), and HDP 295~955 nm (94%). In-vivo delayed static image, inguinal lymph nodes of all experiment groups and two control groups are visible to naked eye. however, $^{99m}Tc-MAG3$ of control groups is not visible to naked eye. Conclusion We were analyzed to the particle size of the radiopharmaceuticals that are used in in-vivo. Consequently, $^{99m}Tc-DPD$, $^{99m}Tc-DMSA $are possible in an alternative radiopharmaceuticals of emergency.

• The Korean Journal of Nuclear Medicine
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• v.39 no.4
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• pp.266-267
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• 2005

Hepatic hemangioma is the most common benign liver tumor and must be considered in the differential diagnosis of other space occupying hepatic masses. A 54-year-old man was referred to evaluate bone metastases of lung adenocarcinoma. In our case, we thought that a focal hepatic uptake in the bore scan was a metastatic lesion, because of underlying lung adenocarcinoma. However, the findings of abdominal CT and Tc-99m RBC scan results were deemed to be characteristic of hepatic hemangioma. The biopsy of the lesion was not performed.

• Proceedings of the Materials Research Society of Korea Conference
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• 2003.03a
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• pp.101-101
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• 2003

Al 박막의 화학증착(CVD)과 Al-Cu 합금박막의 물리증착(PVD)을 조합하는 CVD-PVD Al 공정은 수평방향의 배선과 수직방향의 via를 동시에 형성할 수 있으므로 공정단순화 및 생산원가절감 측면에서 장점이 있어서 DRAM 둥의 반도체 소자의 배선공정으로 매우 유망하다[1]. 본 연구에서는 CVD-PVD Al 공정을 이용하여 초고집적소자의 Al via와 Al 배선을 동시에 형성할 때 층간절연막의 영향을 조사하고 그 원인을 규명하였다. Al CVD를 위한 원료기체로는 dimethylaluminum hydride [($CH_3$)$_2$AlH]를 사용하였고 PVD는 38$0^{\circ}C$에서 실시하였다 층간절연막에 따른 CVD-PVD Al의 via hole 매립특성을 조사한 결과, high-density plasma(HDP) CVD oxide의 경우에는 via hole 매립특성이 우수하였으나, hydrogen silscsquioxane (HSQ)의 경우에는 매립특성이 우수하지 않아서 via 저항이 불균일 하였다. 이는 via 식각 후 wet cleaning 과정에서 HSQ에 흡수된 수분이 lamp를 이용한 degassing 공정에 의해서 완전히 제거되지 않아 CVD-PVD 공정 중에 탈착되어 Al reflow에 나쁜 영향을 미치기 때문으로 판단된다. CVD-PVD 공정 전에 40$0^{\circ}C$, $N_2$ 분위기에서 baking하여 HSQ 내의 수분을 충분히 제거함으로써 via 매립특성을 향상시킬 수 있었다. CVD-PVD Al 공정은 aspect ratio 10:1 이상의 via hole도 완벽하게 매립할 수 있었고 이에의해 제조된 Al 배선은 기존의 W plug 공정에 의해 제조된 배선에 비해 낮은 via 저항을 나타내었다.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.40 no.1
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• pp.30-38
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• 2003

UDP library of Verilog HDL has been used for simulation of digital systems. But it takes a lot of time and efforts to generate a gate-level library equivalent to the UDP library manually due to the characteristic of UDP that does not support synthesis. It is indispensable to generate equivalent gate-level model in testing the digital systems because fault coverage can be reduced without the equivalent gate-level models. So, it is needed to automate the process of generating the equivalent gate-level models. An algorithm to solve this problem has been proposed, but it is unnecessarily complex and time-consuming. This paper suggests a new improved algorithm to implement the conversion to gate-level models, which exploits the characteristic of UDP Experimental results are demonstrated to show the effectiveness of the new algorithm.