Kosin Medical Journal (고신대학교 의과대학 학술지)

Kosin University College of Medicine (고신대학교 의과대학)
권호 표지
DOI QR코드

DOI QR Code

Case Report of Prostate Cancer Patient with Only Lymph Node Involvement on F-18 FDG PET/CT

  • Jung, Hyun Jin (Department of Urology, School of Medicine, Catholic University of Daegu) ;
  • Kang, Sungmin (Department of Nuclear Medicine School of Medicine, Catholic University of Daegu)
  • Received : 2016.02.23
  • Accepted : 2016.07.06
  • Published : 2018.12.31
⟨ Previous Next ⟩

Abstract

We report a case of a patient with locally advanced prostate cancer who had only lymph node involvement without bone metastasis on F-18 FDG PET/CT. A 62-year-old Korean male was admitted to our hospital due to dysuria. His PSA level on admission was 79.35 ng/mL. A transrectal ultrasound-guided prostate biopsy confirmed prostate cancer and his Gleason score was 10 (5+5). F-18 FDG PET/CT demonstrated a hypermetabolic mass lesion with SUVmax 7.0 in the prostate and hypermetabolism with SUVmax 4.7 of the abdominal and pelvic lymph nodes. Tc-99m HDP bone scan showed no significant bone metastasis. The patient underwent hormonal therapy for 9 months. Follow-up F-18 FDG PET/CT showed significantly reduced size and FDG uptake in the prostate and abdominal and pelvic lymph nodes. In this case, treatment monitoring with F-18 FDG PET/CT showed decreased mass size and FDG uptake in the prostate and abdominal and pelvic lymph nodes.

Keywords

References

  1. Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, et al. Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group. J Clin Oncol 2008;26:1148-59. https://doi.org/10.1200/JCO.2007.12.4487
  2. Basu S, Alavi A. Unparalleled contribution of 18F-FDG PET to medicine over 3 decades. J Nucl Med 2008;49:17N-21N, 37N.
  3. Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer 2002;2:683-93. https://doi.org/10.1038/nrc882
  4. Phelps ME. PET: the merging of biology and imaging into molecular imaging. J Nucl Med 2000;41:661-81.
  5. Jadvar H. FDG PET in Prostate Cancer. PET clinics 2009;4:155-61. https://doi.org/10.1016/j.cpet.2009.05.002
  6. Lebret T, Mejean A. [Rare locations of metastases from prostate cancer]. Pro Urol 2008;18:S357-64. https://doi.org/10.1016/S1166-7087(08)74567-6
  7. Venara A, Thibaudeau E, Lebdai S, Mucci S, Ridereau-Zins C, Azzouzi R, et al. Rectal metastasis of prostate cancer: about a case. J Clin med res 2010;2:137-9.
  8. Bowrey DJ, Otter MI, Billings PJ. Rectal infiltration by prostatic adenocarcinoma: report on six patients and review of the literature. Ann R Coll Surg Engl 2003;85:382-5. https://doi.org/10.1308/003588403322520726
  9. Liu L, Devine P, Einhorn E, Kao GD. Incidental finding of an isolated prostate cancer metastasis in an inguinal hernial sac. J Urol 2000;164:457-8. https://doi.org/10.1016/S0022-5347(05)67392-2
  10. Kanamaru H, Oyama N, Akino H, Okada K. [Evaluation of prostate cancer using FDG-PET]. Hinyokika kiyo. 2000;46:851-3.
  11. Liu IJ, Zafar MB, Lai YH, Segall GM, Terris MK. Fluorodeoxyglucose positron emission tomography studies in diagnosis and staging of clinically organ-confined prostate cancer. Urology 2001;57:108-11. https://doi.org/10.1016/S0090-4295(00)00896-7
  12. Jadvar H, Pinski JK, Conti PS. FDG PET in suspected recurrent and metastatic prostate cancer. Oncology reports 2003;10:1485-8.
  13. Agus DB, Golde DW, Sgouros G, Ballangrud A, Cordon-Cardo C, Scher HI. Positron emission tomography of a human prostate cancer xenograft: association of changes in deoxyglucose accumulation with other measures of outcome following androgen withdrawal. Cancer Res 1998;58:3009-14.
  14. Oyama N, Akino H, Suzuki Y, Kanamaru H, Sadato N, Yonekura Y, et al. The increased accumulation of [18F]fluorodeoxyglucose in untreated prostate cancer. Jpn J Oncol 1999;29:623-9. https://doi.org/10.1093/jjco/29.12.623
  15. Sanz G, Robles JE, Gimenez M, Arocena J, Sanchez D, Rodriguez-Rubio F, et al. Positron emission tomography with 18fluorine-labelled deoxyglucose: utility in localized and advanced prostate cancer. BJU Int 1999;84:1028-31.