• Title/Summary/Keyword: HDL Cholesterol

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A Study on the Chemical Compsition and Hypocholesterolaemic Effect of Nostoc commune (돌해파리의 성분 및 혈청 콜레스테롤 저하작용에 관한 연구)

  • 강문선;임상선;이종호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.3
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    • pp.468-474
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    • 1997
  • The chemical composition and hypocholoesterolaemic effect of Nostoc commune were studied. Proximate analysis data, composition of dietary fiber and oxalic acid-ammonium oxalate soluble substance of Nostoc commune were presented. Thirty rats were fed with the one of the following diet for three weeks: The control diet contained 0.75% cholesterol, 0.25% sodium cholate and 5% cellulose powder, CF was cholesterol free, PNC, ONC and RNC diet contained 7.2% powder, 2.2% extracts and 5% residue of Nostoc commune respectively. The lipid components of serum were assayed. The concentration of the total cholesterol was significantly lower in PNC, ONC than the control. The concentration of the total cholesterol was significantly lower in PNC, ONC than the control. The concentration of HDL-choloesterol was significantly higher in PNC than the control. The concentration of LDL, VLDL and chylomicron were comparatively lower in CF and PNC. The concentration of seum triglyceride and phospholipid was lower in PNC group than in the other group.

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Antihyperlipidemic Effects of Fried Beancurd Containing Powdered Green Tea in Rats (녹차유부 섭취가 실험쥐의 혈청지질에 미치는 영향)

  • Yum Yoon-Ki;Lee Mi-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.5 no.6
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    • pp.546-551
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    • 2004
  • Effect of fried beancurd containing powered green tea on the serum lipid metabolism in rats were investigated. HPLC analysis of green tea-fried beancurd showed that epigallocatechin, epicatechin, epicatechin gallate and epigallocatechin gallate were intact without degradation during manufacturing process. Serum HDL-cholesterol, LDL-cholesterol, triglyceride and glucose concentrations were measured in rats fed experimental diet containing green tea-fried beancurd. Serum LDL-cholesterol contents and blood glucose were significantly decreased with treatment of green tea-fried beancurd comparing to control.

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Experimental study on the effects of Luffae fasciculus vascularis(絲瓜絡) on hyperlipidemia (사과락(絲瓜絡)이 Triton Wr 투여로 유발되는 고지혈증(高脂血證) 예방에 미치는 영향에 대한 실험적 연구)

  • Lee Jeong-Seok;Soh Kyung-Sun;Jeong Chan-Gil
    • Journal of Society of Preventive Korean Medicine
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    • v.6 no.2
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    • pp.95-103
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    • 2002
  • In order to study the effect of Luffae fasciculus vascularis(絲瓜絡) on hyperlipidemia, experimental study was performed on Hyperlipidemia induced by Triton WR-1339. Also the level of Total cholesterol, Triglyceride, HDL-cholesterol, Phospholipid and LDL-cholesterol were measured. The results are summarized as follow: In the model of hyperlipidemia Rats induced by Triton WR-1339, luffae fasciculus vascularis(絲瓜絡) had significantly decreasing effects on total cholesterol, triglyceride, phospholipid, LDL-cholesterol in serum and increasing effects on HDL-cholesterol level in serum but were not significant. These results show that Luffae fasciculus vascularis(絲瓜絡) has significantly inhibitory effects on hyperlipidemia and that it could be clinically applied for hyperlipidemia.

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Evaluation of Blood Profile and Meat Color Using Houttuynia cordata Pellet in Duck Diets (오리사료에 어성초 펠렛 첨가 급여로 오리혈액성상과 육색도에 미치는 영향 평가)

  • Jeong, Yeon-Woo
    • Journal of Environmental Science International
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    • v.30 no.5
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    • pp.425-428
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    • 2021
  • The present study evaluated the blood profile and meat color of ducks with Houttuynia cordata (H. cordata) pellets in their diets. In total, 120 pekin ducks (1-d-old) were used in a 42 d growth trial. Ducks were randomly allocated to six pens and exposed to three replicates of two treatments: (1) controls as basal diet and (2) basal diet + 2% H. cordata pellets (T1). Total-cholesterol, HDL-cholesterol, triglyceride contents or L* and b* vaules revealed significant difference (p>0.05) in compared with those in the controls; however, dietary supplementation of H. cordata pellets did not affect (p>0.05) LDL-cholesterol, VLDL-cholesterol and a* values. In conclusion, the inclusion of 2% H. cordata pellets improved HDL-cholesterol and meat color in duck breast and thigh meats, which further reduced other cholesterol values.

The Effects of Yukgunja-tang on the Change of Weight and Serum level in Mice Fed High Fat Diet (육군자탕이 비만마우스의 체중 및 혈청함량변화에 미치는 영향)

  • Tae Bae In;Woo Jeong Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.6
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    • pp.1412-1418
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    • 2003
  • This experimental study was designed to investigate the effects of Yukgunja-tang(YGJT) on the change of weight and serum total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, free fatty acid, total lipid, phospholipid level in obese mice induced by high fat diet. I fed normal group fed normal diet and administered DDW 0.2㎖ during 7 weeks, control group fed high fat diet and administered DDW 0.2㎖ during 7 weeks, sample A group fed high diet and administered YGJT 300mg/kg 0.2㎖ during 7 weeks, sample B group fed high diet and administered YGJT 500mg/kg 0.2㎖ during 7 weeks. The results were as follows ; 1. Sample A and Sample B were significantly decreased body weight(4weeks) and serum free fatty acid level in comparison with control group. 2. Sample A was significantly decreased body weight(7weeks), serum total cholesterol level and serum total lipid level, but significantly increased serum HDL-cholesterol level in comparison with control group. 3. Sample A was decreased serum LDL-cholesterol level, serum triglyceride level and serum phospholipid level in comparison with control group. 4. Sample B was increased serum HDL-cholesterol level in comparison with control group. 5. Sample B was decreased body weight(7weeks), serum total cholesterol level, serum LDL-cholesterol level, serum triglyceride level, serum total lipid level and serum phospholipid level in comparison with control group. According to above results, I suggest YGJT is able to be used for the herbal medication of obesity.

The Characteristics in Obesity Classification Group of College Student by Analyzing Their BMI and Blood Test and the Association between Factors Contributing to Obesity and Obesity according to BMI (대학생 체질량지수와 혈액검사결과 상 비만 분류군간 특성 및 비만 연관 요인 분석에 대한 연구)

  • Park, Jung-Sik;Lee, Jung-Jae;Oh, Hyun-Sook;Lim, Hyung-Ho
    • Journal of Korean Medicine Rehabilitation
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    • v.24 no.4
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    • pp.61-70
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    • 2014
  • Objectives The purpose of this study was to investigate the characteristics in obesity classification group of college students having health checkup by analyzing their BMI and blood test and determine the association between factors contributing to obesity and obesity according to BMI. Methods A group of 2992 test subjects took their medical examination and their body composition, height, weight, blood pressure were measured and blood test was done. With these results we diagnosed obesity, and analysed relationship between obesity and cholesterol, triglyceride, LDL (low density lipoprotein)-cholesterol, HDL (high density lipoprotein)-cholesterol, liver function, renal function and blood pressure. Results 1. Overweight individuals showed high total cholesterol, LDL-cholesterol, triglyceride, GOT (glutamic oxalacetic transaminase), GPT (glutamic pyruvate transaminase), Urea-nitrogen, Creatinine and low HDL-cholesterol. 2. BMI showed a significant association with other factors. BMI has a negative correlation with sex and HDL-cholesterol. BMI had positive correlations with other factors. 3. There was no relation between BMI and sex. Those six factors, liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar were related to BMI. Conclusions There was a significant relation between college students' BMI and their liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar. The diseases related to liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar were clearly associated with obesity.

Effects of Pyroligneous Liquor on Olive, Flaxseed and Perilla Oils in Lipid Metabolism of Mice (Olive Oil, Flaxseed Oil 및 Perilla Oil을 급여한 Mice의 지질대사에 미치는 목초액의 영향)

  • Chung, Keun-Hee;Bang, Nam-Hyu;Shin, Kyung-Ok;Jung, Tae-Hwan;Hwang, Hyo-Jeong;Choi, Kyung-Soon
    • The Korean Journal of Food And Nutrition
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    • v.26 no.2
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    • pp.242-248
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    • 2013
  • Our objectives in this experiment were to study the effects of oils that are high in contents of unsaturated fatty acids (olive, flaxseed, and perilla oils) and pyroligneous liquor on plasma lipid concentrations in mice. Male ICR-mouse (n=10 per group) were fed powdered form diets containing oil and pyroligneous liquor for 60 days. The cholesterol level of the PP group ($96.71{\pm}25.75$ $mg/d{\ell}$) was lower than that of the COW group ($133.56{\pm}21.53$ $mg/d{\ell}$). Levels of triglyceride of COP, CFP, and CPP groups were $121.10{\pm}50.79$ $mg/d{\ell}$, $77.80{\pm}38.58$ $mg/d{\ell}$, and $92.40{\pm}33.04$ $mg/d{\ell}$, respectively (p<0.05). The dietary addition of olive oil increased the plasma lsevels of cholesterol and LDL-cholesterol. On the other hand, the dietary addition of flaxseed oil and pyroligneous liquor increased the plasma level of HDL-cholesterol and decreased the plasma levels of LDL-cholesterol and triglyceride compared with those of the control group. Further, the dietary addition of perilla oil decreased plasma triglyceride but increased HDL-cholesterol. The decrease in the cholesterol level was much higher in the CFP group. In conclusion, the dietary addition of long-term pyroligneous liquor effectively decreased the plasma levels of cholesterol and triglyceride and increased the plasma level of HDL-cholesterol. The additional dietary administration of flaxseed and perilla oils increased the effect of pyroligneous liquor.

The Effect of Medium Chain Triglyceride Diet on the Serum Lipids and Lipoprotein Levels of Rats Fed with Cholesterol (Medium Chain Triglyceride첨가(添加) 식이(食餌)가 Cholesterol투여(投與) 흰쥐의 혈중(血中) 지질(脂質) 및 Lipoporotein에 미치는 영향(影響))

  • Lee, Yong-Ock;Cha, Jae-Seon
    • Journal of the Korean Applied Science and Technology
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    • v.1 no.1
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    • pp.11-21
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    • 1984
  • The purpose of the study was to find an effect of medium chain triglyceride (MCT)diet on the serum lipids and lipoprotein of Sprague-Dawley rats when the were fed with cholesterol. All experiment-groups were fed with different diet such as soybean oil, shortening,MCT and MCT mixed with oil respectively. After fed to each group, the levels of serum lipids and lipoprotein among fed rats were examined and the data from the experiment were compared with a control group. The results obtained from the study are as follows : (1) The average boby weight gain in MCT diet and soybean oil diet groups were lighter than that of the control group, while the food efficiency ratio in each experimental diet group was almost same as than in the control group. (2) Total cholesterol levels in serum of all experimental diet groups were lower than that of the control group except the level in shortening diet group. Especially, the levels of total cholesterol in MCT diet and soybean oil diet groups were significantly lower than that of the control group. (3) VLDL, LDL-cholesterol levels of all experimental groups were almost same except the case of the MCT diet and soybean oil diet group which was significantly low. (4) The ratio of VLDL, LDL-cholesterol to HDL-cholesterol, so called, atherogenic index in serum of MCT and soybean oil diet groups were significantly lower than that of the control group. (5) The ratio of total cholesterol to phospholipids in serum of MCT diet group was decreased, because total cholesterol levels were decreased more than phospolipid levels. (6) The ratio of the serum VLDL, LDL to HDL in MCT diet group. in MCT and soybean oil mixed diet group, and in soybean diet group was decreased. In other wards, it means that the decrease of the serum VLDL, LDL in each group and the increase of the serum HDL.

Effects of Varied Mushroom on Lipid Compositions in Dietary Hypercholesterolemic Rats (고콜레스테롤혈증 유발 흰쥐에 있어서 버섯류가 지질 성분에 미치는 영향)

  • 김군자;김한수;정승용
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.21 no.2
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    • pp.131-135
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    • 1992
  • For the investigation of the effects of mushrooms on prevention of hypercholesterolemia, dietary hyperc-holesterolemic rats were fed for 2 weeks with basal diet containing 5% G. lucidum, 5% L. edodes, 5% A. judae and 10% G. lucidum, 10% L. ededos or 10% A. judae mushroom. Concentrations of total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, phospholipid, free-cholesterol, cholesteryl ester, VLDL and chylomicron in serum were analyzed. The result obtained are as follows : Concentrations of total cholesterol, LDL, LDL-cholesterol in serum were lowest in the group 6 (10% L. edodes mushroom) and HDL-cholesterol concentration in serum was significantly higher than the concentrations of the control group. Concentrations of triglyceride, phospholipid, free-cholesterol, cholesteryl ester in serum were lower than the concentration of the control group, and the concentrations of triglyceride, cholesteryl ester in group 6 were lower than those of the other groups. Concentrations of phospholipid and free-cholesterol in group 3 were lower than those of the other groups.

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Experimental and Clinical Study on Hyperlipidemia of Tongbiyeum (고지혈증에 대한 통비음의 실험 및 임상적 고찰)

  • Jo Hyun Kyung;Oh Yong Sung;Kim Yong Jin;Oh Young Sun;Seol In Chan
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.4
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    • pp.1092-1096
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    • 2003
  • This study was carried out to investigate the clinical effects of Tongbiyeum(TBY) ₂on hyperlipidemia. The hyperlipidemia of rats was induced by feeding high cholesterol diet for 4 weeks. We checked serum lipids and body weight weekly for 4 weeks. After the termination of treatment, we measured liver weight and observed histopathological change. We compared result of TBY group with control group. Thereafter, we made a study of 37 hyperlipidemic patients who visited us, the oriental medical center Daejeon and cheongju of Daejeon University, from November, 2001 to April, 2002. After administering TBY for 1 month, we followed up their total cholesterol, triglyceride and HDL-Cholesterol levels. The results were as follows; TBY treatment inhibited the liver weight gain induced by high cholesterol diet as compared with control group. TBY treatment inhibited lipid droplet accumulation and apoptotic change in liver as compared with control group. TBY treatment significantly inhibited the increasing of serum triglyceride and total cholesterol levels induced by high cholesterol diet as compared with control group but not affect HDL-cholesterol level. After administering TBY, the serum total cholesterol, triglyceride and LDL-cholesterol levels of hyperlipidemic patients were decreased significantly. After administering TBY, the serum HDL-Cholesterol level of hyperlipidemic patients had no significant changes. According to above mentioned results, we can infer that TBY has hypolipidemic effect to be applicable to artheriosclerosis.