• 제목/요약/키워드: HBF

검색결과 20건 처리시간 0.026초

Oleic acid in Angus and Hanwoo (Korean native cattle) fat reduced the fatty acid synthase activity in rat adipose tissues

  • Nogoy, Kim Margarette C.;Kim, Hyoun Ju;Lee, Dong Hoon;Smith, Stephen B.;Seong, Hyun A;Choi, Seong Ho
    • Journal of Animal Science and Technology
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    • 제63권2호
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    • pp.380-393
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    • 2021
  • This study aimed to determine the blood lipid profiles, fatty acid composition, and lipogenic enzyme activities in rat adipose tissues as affected by the Angus beef fat (ABF) and Hanwoo beef fat (HBF) containing high oleic acid (OA) content. We assigned 60 Sprague Dawley rats with a mean bodyweight of 249 ± 3.04 g to three groups (n = 20 each) to receive diets containing 7% coconut oil (CON), 7% ABF, or 7% HBF. The OA content was highest in the HBF (45.23%) followed by ABF (39.51%) and CON (6.10%). The final body weight of the HBF-fed group was significantly increased, probably due to increased feed intake, indicating the palatability of the diet. The HBF and ABF significantly increased high-density lipoprotein cholesterol (HDL-C), decreased triglyceride (TG) and total cholesterol (TC) levels, and also tended to attenuate glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) levels in the bloodstream of the rats compared to CON. As compared to CON, lauric, myristic, and palmitic acids were significantly lower, and those of OA and α-linolenic acid (ALA) were significantly higher in the adipose tissues of HBF and ABF-fed groups. The HBF and ABF also reduced lipogenesis as induced by depleted fatty acid synthase (FAS) activity in rat adipose tissues. Nevertheless, between the two fats, HBF showed high feed intake due to its high palatability but reduced lipogenic enzyme activity, specifically that of FAS, and increased HDL-C, decreased TC and TG levels in the bloodstream, reduced saturated fatty acids (SFA), and increased oleic and ALA contents in rat adipose tissues indicating that HBF consumption does not pose significant risks of cardiovascular disease.

Facile Synthesis of Natural Moracin Compounds using Pd(OAc)2/P(tBu)3-HBF4 as a Sonogashira Coupling Reagent

  • Lee, Jae Jun;Yun, So-Ra;Jun, Jong-Gab
    • Bulletin of the Korean Chemical Society
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    • 제35권12호
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    • pp.3453-3458
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    • 2014
  • An efficient and practical synthesis of natural moracins, which have diverse range of biological properties including anticancer, antioxidant, and antibacterial activities, has been achieved using $Pd(OAc)_2/P(^tBu)_3-HBF_4$ as a Sonogashira coupling reagent which solved the unreactive problems in case of higher electron density of haloaryl compounds in the reaction. Lowering electron density of halophenol with acetylation and changing Sonogashira coupling reagent from $PdCl_2(PPh_3)_2$ to $Pd(OAc)_2/P(^tBu)_3-HBF_4$ smoothly produce the benzofuran structures in the syntheses of moracins M, N and S. The electron deficient halobenzaldehyde, however, easily forms the benzofuran using original Sonogashira conditions, and utilized for the first synthesis of moracin Y.

편광상이 고리 기반 2차 광섬유 유연 빗살 필터의 투과 스펙트럼 특성 분석 (Analysis of Transmission Spectrum Characteristics of Second-Order Fiber Flexible Comb Filter Based on Polarization-Diversity Loop)

  • 박경수;이용욱
    • 조명전기설비학회논문지
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    • 제29권12호
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    • pp.1-7
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    • 2015
  • In this paper, we propose a second-order fiber flexible comb filter based on a polarization-diversity loop(PDL). The proposed filter consists of a polarization beam splitter, four half-wave plates(HWPs), and three high birefringence fiber(HBF) segments. In the previous Solc-type second-order filter based on the PDL, HBF segments were fusion-spliced with a fixed angle offset between their principal axes with each other. But, the proposed filter implemented by inserting two HWPs between three HBF segments has a great flexibility in adjusting relative angular difference between the principal axes of two adjacent HBF segments. Owing to this flexibility, second-order transmission spectra, which had a channel spacing of ~0.8nm, could be interleaved by controlling the orientation angles of four HWPs. The output transmission spectra of the proposed filter were theoretically analyzed and experimentally verified.

오디오용 24bit 시그마-델타 D/A 컨버터 구현 (Implementation of 24bit Sigma-delta D/A Converter for an Audio)

  • 허정화;박상봉
    • 한국인터넷방송통신학회논문지
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    • 제8권4호
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    • pp.53-58
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    • 2008
  • 본 논문은 고 해상도 및 저 전력을 가지는 시그마-델타 D/A(Digital-to-Analog) 컨버터를 구현하였다. A/D 컨버터의 출력을 채널당 1비트씩 입력 받아 LJ, RJ, I2S 모드와 비트 모드에 따라서 입력 데이터를 재구성한다. D/A 컨버터는 HBF(Half Band Filter)와 Hold, 5차 CIFB Sigma-Delta 변조기를 통과하여 원래의 아날로그 신호로 복원한다. 면적과 전력, 성능을 고려하여 곱셈 연산 대신 덧셈 연산을 반복 사용하였다. 또한, 비슷한 구조의 HBF 3개를 하나의 블록으로 구성하였고, sinc 필터 대신에 샘플-홀드 블록을 사용하여, 면적을 감소시키는 간략한 D/A 구조를 제안하였다. 블록안의 각 필터들은 매트랩 툴을 이용하여 특성을 평가하였다. 전체 블록은 Top-down 설계 방식을 사용하여, Verilog 언어로 설계하였다. 설계된 블록은 Samsung 0.35um CMOS 표준 셀 라이브러리를 사용해 칩으로 제작되었다. 칩의 면적은 1500 * 1500um 이다.

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파일럿 송출 AF 중계기와 이를 이용한 빔포밍 기법 (Pilot Emitting AF Relays and Its Applications to Beamforming)

  • 정진곤;이창수;이용훈
    • 한국통신학회논문지
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    • 제33권12A호
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    • pp.1165-1171
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    • 2008
  • 본 논문에서는 기존 다중안테나 빔포밍 (beamforming) 시스템에 적용할 수 있도록 파일럿을 송출하는 단일 안테나 AF방식 중계기와 (amplify-and-forward relays) 이를 이용하는 빔포밍 기법을 제안한다. 먼저 송신기-중계기 채널과 중계기-수신기 채널이 곱해진 전체 채널에 대해서 빔포밍을 수행하는 OBF(overall beamforming)를 소개하고, 송신기-중계기 채널과 중계기-수신기 채널 각각에 대해 독립적으로 빔포밍을 수행하는 HBF (hop-by-hop beamforming) 방식을 제안한다. 수학적 분석 및 컴퓨터 모의실험을 통해, 채널 추정이 완벽할 때, HBF와 OBF의 성능이 동일함을 보이고, 나아가 실제 채널 추정 시나리오를 고려할 때, 제안한 파일럿 송출 중계기를 이용하는 HBF가 OBF에 비해 채널 추정 성능이 우수하고, 비트 오류율 (bit error rate: BER) 성능이 향상됨을 확인하였다.

Effect of bFGF and fibroblasts combined with hyaluronic acid-based hydrogels on soft tissue augmentation: an experimental study in rats

  • Lee, Su Yeon;Park, Yongdoo;Hwang, Soon Jung
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제41권
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    • pp.47.1-47.10
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    • 2019
  • Background: Hyaluronic acid (HA) has been applied as a primary biomaterial for temporary soft tissue augmentation and as a carrier for cells and the delivery of growth factors to promote tissue regeneration. Although HA derivatives are the most versatile soft tissue fillers on the market, they are resorbed early, within 3 to 12 months. To overcome their short duration, they can be combined with cells or growth factors. The purpose of this study was to investigate the stimulating effects of human fibroblasts and basic fibroblast growth factors (bFGF) on collagen synthesis during soft tissue augmentation by HA hydrogels and to compare these with the effects of a commercial HA derivative (Restylane®). Methods: The hydrogel group included four conditions. The first condition consisted of hydrogel (H) alone as a negative control, and the other three conditions were bFGF-containing hydrogel (HB), human fibroblast-containing hydrogel (HF), and human fibroblast/bFGF-containing hydrogel (HBF). In the Restylane® group (HGF), the hydrogel was replaced with Restylane® (R, RB, RF, RBF). The gels were implanted subdermally into the back of each nude mouse at four separate sites. Twelve nude mice were used for the hydrogel (n = 6) and Restylane® groups (n = 6). The specimens were harvested 8 weeks after implantation and assessed histomorphometrically, and collagen synthesis was evaluated by RT-PCR. Results: The hydrogel group showed good biocompatibility with the surrounding tissues and stimulated the formation of a fibrous matrix. HBF and HF showed significantly higher soft tissue synthesis compared to H (p < 0.05), and human collagen type I was well expressed in HB, HF, and HBF; HBF showed the strongest expression. The Restylane® filler was surrounded by a fibrous capsule without any soft tissue infiltration from the neighboring tissue, and collagen synthesis within the Restylane® filler could not be observed, even though no inflammatory reactions were observed. Conclusion: This study revealed that HA-based hydrogel alone or hydrogel combined with fibroblasts and/or bFGF can be effectively used for soft tissue augmentation.

PVA-g-PAA 가지형 공중합체 기반 촉진수송 분리막 (Facilitated Transport Membranes Based on PVA-g-PAA Graft Copolymer)

  • 박민수;강미소;박보령;김정훈;김종학
    • 멤브레인
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    • 제31권3호
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    • pp.212-218
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    • 2021
  • 화석 연료를 사용할 때, 불완전 연소는 필연적으로 발생하는 문제이다. 이러한 관점에서 연소 후 기체 분리는 불완전 연소 기체의 재활용 가능성을 시사한다. 이와 관련하여 본 연구에서는 일산화탄소 기체 분리용 촉진수송 고분자 분리막을 제조하였다. 이를 위해 poly(vinyl alcohol) (PVA) 주사슬 기반으로 acrylic acid (AA) 단량체를 자유 라디칼 중합법으로 PVA-g-PAA 공중합체를 제조하였다. 본 공중합체를 일산화탄소 활용에 적용하는 사례는 처음이며, 제조한 공중합체는 AgBF4 염과 HBF4를 혼합하여 기체 분리막에 적용하였다. 공중합체 합성 결과는 FT-IR을 통해 분석하였으며, 공중합체와 AgBF4, HBF4의 상호작용은 TEM를 통해 분석하였다. 염의 첨가를 통해 일산화탄소 기체의 촉진수송 채널을 형성하였으며 이를 통해 일산화탄소 분리막 분야에 촉진수송 및 그래프팅 방법이라는 새로운 접근법을 제시하였다.

Ag계 도체 및 RuO2계 저항체 페이스트의 특성에 미치는 무연계 글라스 프릿트 조성의 영향 (Effect of Lead Free Glass Frit Compositions on Properties of Ag System Conductor and RuO2 Based Resistor Pastes)

  • 구본급
    • 한국전기전자재료학회논문지
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    • 제24권3호
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    • pp.200-207
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    • 2011
  • Abstract: The effect of lead free glass frit compositions on the properties of thick film conductor and resistor pastes were investigated. Two types lead free frits, HBF-A(without $Bi_2O_3$) and HBF-B(with $Bi_2O_3$) were made from $SiO_2$, $B_2O_3$, $Al_2O_3$, CaO, MgO, $Na_2O$, $K_2O$, ZnO, MnO, $ZrO_2$, $Bi_2O_3$. And Ag based conductor pastes and $RuO_2$ based resistor paste were prepared by mixed with these frits and functional phase(Ag and $RuO_2$), and organic vehicle. The properties of thick film conductor and resistor sintered at $850^{\circ}C$ were studied after printing on $Al_2O_3$ substrate. The morphology of the sintered films surface were SEM and EDS were carried out to analysis the chemical composition on resistor surface and state of Ru atom in frit matrix.