• Title/Summary/Keyword: HBF

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Oleic acid in Angus and Hanwoo (Korean native cattle) fat reduced the fatty acid synthase activity in rat adipose tissues

  • Nogoy, Kim Margarette C.;Kim, Hyoun Ju;Lee, Dong Hoon;Smith, Stephen B.;Seong, Hyun A;Choi, Seong Ho
    • Journal of Animal Science and Technology
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    • v.63 no.2
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    • pp.380-393
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    • 2021
  • This study aimed to determine the blood lipid profiles, fatty acid composition, and lipogenic enzyme activities in rat adipose tissues as affected by the Angus beef fat (ABF) and Hanwoo beef fat (HBF) containing high oleic acid (OA) content. We assigned 60 Sprague Dawley rats with a mean bodyweight of 249 ± 3.04 g to three groups (n = 20 each) to receive diets containing 7% coconut oil (CON), 7% ABF, or 7% HBF. The OA content was highest in the HBF (45.23%) followed by ABF (39.51%) and CON (6.10%). The final body weight of the HBF-fed group was significantly increased, probably due to increased feed intake, indicating the palatability of the diet. The HBF and ABF significantly increased high-density lipoprotein cholesterol (HDL-C), decreased triglyceride (TG) and total cholesterol (TC) levels, and also tended to attenuate glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) levels in the bloodstream of the rats compared to CON. As compared to CON, lauric, myristic, and palmitic acids were significantly lower, and those of OA and α-linolenic acid (ALA) were significantly higher in the adipose tissues of HBF and ABF-fed groups. The HBF and ABF also reduced lipogenesis as induced by depleted fatty acid synthase (FAS) activity in rat adipose tissues. Nevertheless, between the two fats, HBF showed high feed intake due to its high palatability but reduced lipogenic enzyme activity, specifically that of FAS, and increased HDL-C, decreased TC and TG levels in the bloodstream, reduced saturated fatty acids (SFA), and increased oleic and ALA contents in rat adipose tissues indicating that HBF consumption does not pose significant risks of cardiovascular disease.

Facile Synthesis of Natural Moracin Compounds using Pd(OAc)2/P(tBu)3-HBF4 as a Sonogashira Coupling Reagent

  • Lee, Jae Jun;Yun, So-Ra;Jun, Jong-Gab
    • Bulletin of the Korean Chemical Society
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    • v.35 no.12
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    • pp.3453-3458
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    • 2014
  • An efficient and practical synthesis of natural moracins, which have diverse range of biological properties including anticancer, antioxidant, and antibacterial activities, has been achieved using $Pd(OAc)_2/P(^tBu)_3-HBF_4$ as a Sonogashira coupling reagent which solved the unreactive problems in case of higher electron density of haloaryl compounds in the reaction. Lowering electron density of halophenol with acetylation and changing Sonogashira coupling reagent from $PdCl_2(PPh_3)_2$ to $Pd(OAc)_2/P(^tBu)_3-HBF_4$ smoothly produce the benzofuran structures in the syntheses of moracins M, N and S. The electron deficient halobenzaldehyde, however, easily forms the benzofuran using original Sonogashira conditions, and utilized for the first synthesis of moracin Y.

Analysis of Transmission Spectrum Characteristics of Second-Order Fiber Flexible Comb Filter Based on Polarization-Diversity Loop (편광상이 고리 기반 2차 광섬유 유연 빗살 필터의 투과 스펙트럼 특성 분석)

  • Park, Kyoungsoo;Lee, Yong Wook
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.29 no.12
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    • pp.1-7
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    • 2015
  • In this paper, we propose a second-order fiber flexible comb filter based on a polarization-diversity loop(PDL). The proposed filter consists of a polarization beam splitter, four half-wave plates(HWPs), and three high birefringence fiber(HBF) segments. In the previous Solc-type second-order filter based on the PDL, HBF segments were fusion-spliced with a fixed angle offset between their principal axes with each other. But, the proposed filter implemented by inserting two HWPs between three HBF segments has a great flexibility in adjusting relative angular difference between the principal axes of two adjacent HBF segments. Owing to this flexibility, second-order transmission spectra, which had a channel spacing of ~0.8nm, could be interleaved by controlling the orientation angles of four HWPs. The output transmission spectra of the proposed filter were theoretically analyzed and experimentally verified.

Implementation of 24bit Sigma-delta D/A Converter for an Audio (오디오용 24bit 시그마-델타 D/A 컨버터 구현)

  • Heo, Jeong-Hwa;Park, Sang-Bong
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.8 no.4
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    • pp.53-58
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    • 2008
  • This paper designs sigma-delta D/A Converter with a high resolution and low power consumption. It reorganizes the input data along LJ, RJ, I2S mode and bit mode to the output data of A/D converter. The D/A converter decodes the original analog signal through HBF, Hold and 5th CIFB(Cascaded Integrators with distributed Feedback as well as distributed input coupling) sigma-delta modulation blocks. It uses repeatedly the addition operation in instead of the multiply operation for the chip area and the performance. Also, the half band filters of similar architecture composed the one block and it used the sample-hold block instead of the sinc filter. We supposed simple D/A Converter decreased in area. The filters of the block analyzed using the matlab tool. The top block designed using the top-down method by verilog language. The designed block is fabricated using Samsung 0.35um CMOS standard cell library. The chip area is 1500*1500um.

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Pilot Emitting AF Relays and Its Applications to Beamforming (파일럿 송출 AF 중계기와 이를 이용한 빔포밍 기법)

  • Joung, Jin-Gon;Lee, Chang-Soo;Lee, Yong-Hoon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.12A
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    • pp.1165-1171
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    • 2008
  • In this paper, a pilot emitting amplify-and-forward relay and its beamforming schemes, OBF (overall beamforming) and RBF (hop-by-hop beamforming), are proposed for two-hop relaying systems. The OBF performs beamforming with respect to a overall channel from a source node (SN) to a destination node (DN) through a relay node (RN), while the proposed RBF performs two independent beamformings: from the SN to the RN and from the RN to the DN. From our analytic and numerical results, it is shown that bit-error-rate (BER) performance of the proposed RBF is better than that of the OBF scheme since the RBF system can estimate channel more proper than the CBF system, which is verified by deriving and comparing the mean square errors of the channel estimation.

Effect of bFGF and fibroblasts combined with hyaluronic acid-based hydrogels on soft tissue augmentation: an experimental study in rats

  • Lee, Su Yeon;Park, Yongdoo;Hwang, Soon Jung
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.41
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    • pp.47.1-47.10
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    • 2019
  • Background: Hyaluronic acid (HA) has been applied as a primary biomaterial for temporary soft tissue augmentation and as a carrier for cells and the delivery of growth factors to promote tissue regeneration. Although HA derivatives are the most versatile soft tissue fillers on the market, they are resorbed early, within 3 to 12 months. To overcome their short duration, they can be combined with cells or growth factors. The purpose of this study was to investigate the stimulating effects of human fibroblasts and basic fibroblast growth factors (bFGF) on collagen synthesis during soft tissue augmentation by HA hydrogels and to compare these with the effects of a commercial HA derivative (Restylane®). Methods: The hydrogel group included four conditions. The first condition consisted of hydrogel (H) alone as a negative control, and the other three conditions were bFGF-containing hydrogel (HB), human fibroblast-containing hydrogel (HF), and human fibroblast/bFGF-containing hydrogel (HBF). In the Restylane® group (HGF), the hydrogel was replaced with Restylane® (R, RB, RF, RBF). The gels were implanted subdermally into the back of each nude mouse at four separate sites. Twelve nude mice were used for the hydrogel (n = 6) and Restylane® groups (n = 6). The specimens were harvested 8 weeks after implantation and assessed histomorphometrically, and collagen synthesis was evaluated by RT-PCR. Results: The hydrogel group showed good biocompatibility with the surrounding tissues and stimulated the formation of a fibrous matrix. HBF and HF showed significantly higher soft tissue synthesis compared to H (p < 0.05), and human collagen type I was well expressed in HB, HF, and HBF; HBF showed the strongest expression. The Restylane® filler was surrounded by a fibrous capsule without any soft tissue infiltration from the neighboring tissue, and collagen synthesis within the Restylane® filler could not be observed, even though no inflammatory reactions were observed. Conclusion: This study revealed that HA-based hydrogel alone or hydrogel combined with fibroblasts and/or bFGF can be effectively used for soft tissue augmentation.

Facilitated Transport Membranes Based on PVA-g-PAA Graft Copolymer (PVA-g-PAA 가지형 공중합체 기반 촉진수송 분리막)

  • Park, Min Su;Kang, Miso;Park, Bo Ryoung;Kim, Jeong-Hoon;Kim, Jong Hak
    • Membrane Journal
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    • v.31 no.3
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    • pp.212-218
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    • 2021
  • It is inevitable to generate incomplete combustion gases when mankind utilizes fossil fuels. From this point of view, gas separation process of combustion gas suggests the possibility of recycling CO gas. In this study, we fabricated a facilitated transport polymeric composite membrane for CO separation using AgBF4 and HBF4. The copolymer was synthesized via free-radical polymerization of poly(vinyl alcohol) (PVA) as a main chain and acrylic acid (AA) monomer as a side chain. The polymer synthesis was confirmed by FT-IR and the interactions of graft copolymer with AgBF4, and HBF4 were characterized by TEM. PVA-g-PAA graft copolymer membranes showed good channels for facilitated CO transport. In this perspective, we suggest the novel approach in CO separation membrane area via combination of grafting and facilitated transport.

Effect of Lead Free Glass Frit Compositions on Properties of Ag System Conductor and RuO2 Based Resistor Pastes (Ag계 도체 및 RuO2계 저항체 페이스트의 특성에 미치는 무연계 글라스 프릿트 조성의 영향)

  • Koo, Bon-Keup
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.24 no.3
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    • pp.200-207
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    • 2011
  • Abstract: The effect of lead free glass frit compositions on the properties of thick film conductor and resistor pastes were investigated. Two types lead free frits, HBF-A(without $Bi_2O_3$) and HBF-B(with $Bi_2O_3$) were made from $SiO_2$, $B_2O_3$, $Al_2O_3$, CaO, MgO, $Na_2O$, $K_2O$, ZnO, MnO, $ZrO_2$, $Bi_2O_3$. And Ag based conductor pastes and $RuO_2$ based resistor paste were prepared by mixed with these frits and functional phase(Ag and $RuO_2$), and organic vehicle. The properties of thick film conductor and resistor sintered at $850^{\circ}C$ were studied after printing on $Al_2O_3$ substrate. The morphology of the sintered films surface were SEM and EDS were carried out to analysis the chemical composition on resistor surface and state of Ru atom in frit matrix.