• Journal of Haehwa Medicine
• /
• v.14 no.1
• /
• pp.179-186
• /
• 2005

In oriental medicine, Achyranthis Bidentatae Radix & Dipsaci Radix are frequently used materials for strenthing lumbar and knees. Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescription book. In Bang-Yak-Hap-Pyun, Achyranthis Bidentatae Radix is used 1g~8g. and Dipsaci Radix is used 1g~3.2g. The most important fact is that the prescription used chyranthis Bidentatae Radix & Dipsaci Radix at the same time is only 1(Man-Geum-Tang-the ratio of Achyranthis Bidentatae Radix & Dipsaci Radix is 1:1). The number of prescription Achyranthis Bidentatae Radix & Dipsaci Radix in Bang-Yak-Hap-Pyun is total 19. 14 in sang-tong(上統), 2 in jung-tong(中統), 3 in ha-tong(下統). The group of mostly used disease is about lumbar and knees. The ratio of Achyranthis Bidentatae Radix in Bang-Yak-Hap-Pyun is 3.88%~25%. And the ratio of Dipsaci Radix is 8.33%~12.5%. The mostly quoted medical literature what prescription included Achyranthis Bidentatae Radix & Dipsaci Radix in Bang-Yak-Hap-Pyun is Dong-Yi-Bo-Gam and Gyung-Ak-Jun-Su Sin-Bang-Pal-Jin.

• Proceedings of the Materials Research Society of Korea Conference
• /
• 2009.05a
• /
• pp.48.2-48.2
• /
• 2009

Ti와 Ti-6%Al-4%V합금은 내 부식성 및 생체 적합성이 매우 우수하기 때문에 현재 생체재료로써 널리 사용되고 있다. 하지만 Ti-6%Al-4V합금에 포함된 Al과 V이 신체에 좋지 않은 영향을 줄 수 있다는 연구 결과가 보고되면서 새로운 생체재료의 연구가 활발히 진행되고 있다. 본 연구에서는 생체에 무해한 Ti-Nb와 hydroxyapatite(HAp)를 복합 첨가하여 고에너지볼밀링(high-energy mechanical milling, HEMM)으로 나노 합금분말을 제조 후 급속소결에 의하여 Ti-Nb/HAp 생체재료를 제조 하였다. 제조한 Ti-Nb/HAp 생체용 복합재료에서 HAp 첨가량과 분말의 밀링, 믹싱에 따른 조직 변화와 소결체의 생체적합성의 변화 및 기계적 특성의 변화를 분석하였다. 이때 Ti-42%Nb에 HAp의 첨가량을 0%, 5%, 10%, 15%로 변화를 주었고, 밀링은 고에너지볼밀링기를 이용하여 0~8시간 동안 실시하였다. 그 결과 밀링 시간이 증가할수록 합금 분말의 크기가 미세해졌으며, 특히 8시간 밀링시 분말의 크기가 나노 크기로 감소하여 기계적 특성(경도 및 강도)이 우수해지는 것을 알 수 있었다.

• Korean Journal of Materials Research
• /
• v.15 no.7
• /
• pp.444-447
• /
• 2005

In this study, $Hydroxyapatite+TiO_2(HAp+TiO_2)$ composite sol coatings on Cp-Ti substrates were deposited by using a sol-gel derived precursor. Prior to hydroxyapatite coating, the samples were micropolished and divided into three sets. The first set was coated with hydroxyapatite (HAp) directly on Cp-Ti. The second set was first coated with intermediate titania layer and then coated with HAp. The third set samples were coated with $HAp+TiO_2$ (50:50) composite sol. Each samples were predried at $200^{\circ}C$, and heat treated at $600^{\circ}C$. The formation of hydroxyapatite has been confirmed by XRD analyses and the substrate material was found to be oxidized with negligible amount of CaO in the coating. The NaOH treated samples showed the presence of rutile crystal. The SEM studies revealed surface morphologies of each samples. $HAp+TiO_2$ composite sol coating layer was found to be smooth. The bonding strength of each samples were calculated using pull out tests. The bonding strength of the $HAp+TiO_2$ composite sol coating on substrate was 29.35MPa.

• Journal of the Korean institute of surface engineering
• /
• v.32 no.3
• /
• pp.307-311
• /
• 1999

The well-crystalline hydroxyapatite($Ca_{10}(PO_4)_6(OH)_2$ ; HAp) layer having a biocompatibility was successfully coated onto titanium substrate using a radio-frequency magnetron sputtering, and effects of sputtering gas and the thickness of HAp film on a crystal growth of the HAp layers were investigated. The deposition rate of the layer sputtered with water-vapour gas was slower than that of the layer sputtered with argon gas. The results of X-ray diffraction demonstrated that the about $0.8\mu\textrm{m}$ thick HAp film under water-vapour gas was an amorphous phase, the about $1.2\mu\textrm{m}$ thick film was (100) plane-oriented HAp, and the about $1.5\mu\textrm{m}$ thick film was (001)plane-oriented HAp. FT-IR analysis proved that hydroxyl group of the layer sputtered with argon gas was defected, but that of the layer sputtered with water-vapour gas was not defected. From these results, it was favorable to use water-vapour gas on the HAp coatings onto metal surface.

• Korean Journal of Food Science and Technology
• /
• v.47 no.6
• /
• pp.751-756
• /
• 2015

Sodium chloride is known to contribute to the quality and safety of foods. However, there is an increasing interest in reducing the sodium content in foodstuffs, owing to health-related concerns related to its overconsumption. Therefore, the possible use of enzymatically hydrolyzed anchovy protein (eHAP) in enhancing the intensity of the salty taste in model broth was investigated in this study. The sodium chloride content of eHAP was 67.7 g/L. The lightness (L) and yellowness (b) of the model broth increased with increasing eHAP concentration. Additionally, the perceived intensity of the salty taste of eHAP solutions increased with increasing amounts of eHAP at a given NaCl concentration in the model broth. The intensity of the salty taste was enhanced by 0.37-35.58% as eHAP was added. The results suggest that it may be possible to reduce the sodium chloride content in foods by enhancing the salty taste with eHAP.

• Korean Journal of Materials Research
• /
• v.11 no.2
• /
• pp.120-125
• /
• 2001

Generally, hydroxyapatite(HAp), zeolite, carbon molecular sieve , activated carbon and alumina are used as heavy metal ions adsorption materials. Among those adsorption materials, HAp which has good positive ion-exchange ability with metal ion, and zeolite are utilized in wastewater treatment. Most of water pollutions are caused by hazardous heavy metals ions as well as bacteria in waste water. In this study, a adsorption materials (HAP and zeolite) are ion-exchanged with a well known antimicrobial metal ions, such as $Ag^+,\;Cu^{2+},\;and\;Zn^{2+}$, in order to give a adsorption of heavy metal ions and a killing effects of bacteria. The antimicrobial effects of adsorption materials are observed using by E. Coli. The results show that there is a complete antimicrobial effect in the adsorption materials with $Ag^+$ at the concentration of $1{\times}10^{-4}$cell/$m\ell$ of E. Coli until 24 hours. However, there is not good antimicrobial effects in the adsorption materials with $Cu^{2+},\;and\;Zn^{2+}$ substitution. Feng et. al. showed the denaturation effects of silver ions which induces the condensed DNA molecules and losing their replication abilities.

• Proceedings of the Korean Fiber Society Conference
• /
• 2002.04a
• /
• pp.455-458
• /
• 2002

Hydroxyapatite(HAp)는 인체의 뼈를 구성하는 주성분으로 생체친화성, 단백질 흡착성, 항균성 등이 우수하여 정형외과 분야의 골 대체제로 사용되어 오고 있다[3]. 하지만, HAp는 너무 딱딱하고 부서지기 쉬워 특별한 형태로의 성형이 어렵고, 이식된 부분으로부터 쉽게 떨어져 나오는 문제점을 갖고 있다[1,2] 따라서 HAp의 이러한 기계적인 특성을 보완할 수 있는 HAp/유기물질 복합소재 개발에 대한 관심이 증대되고 있다. (중략)

• Proceedings of the Korea Air Pollution Research Association Conference
• /
• 1999.10a
• /
• pp.385-386
• /
• 1999

국내에서도 대기중 VOC 측정이 정부 차원에서 각 지역별로 이루어지도록 법적 시행이 2000년부터 이루질 예정이다. VOC 분석에서 가장 필요한 것은 VOC분석용 표준물질인데 이는 매우 고가로서 모두 수입에 의존하고 있다. 본 연구에서는 앞으로 시행된 대기중 VOC 측정 대상 화합물중 10개의 HAP(hazardous air pollutant) target화합물이 함유된 저농도 ppb level의 HAP CRM을 개발하였다.(중략)

• Korean Journal of Materials Research
• /
• v.14 no.6
• /
• pp.375-378
• /
• 2004

The samples were prepared with hydroxyapatite(HAp) powder and eugenol (Eugenol/HAp = 15, 20, 25, 30wt%). The samples were dried at room temperature. The higher mechanical properties was observed in HAp sample with 25wt% Eugenol. The average compressive and bending strength in HAp with 25wt% Eugenol are 542 kgf/$\textrm{mm}^2$ and 366 kgf/$\textrm{mm}^2$ respectively. This strength is higher compare to that of the cortical bone.

• Analytical Science and Technology
• /
• v.13 no.2
• /
• pp.208-214
• /
• 2000

The formation and dissolution of hydroxides, carbonates and hydroxyapatite (HAp), which depend on the pH of solution, are important factor for the preparation of homogeneous and fine HAp, $Ca_{10-x}(HPO_4)_x(PO_4)_{6-x}(OH)_{2-x}(x=0)$, ceramic powder from the $Ca-PO_4-H_2O$ system. Since the solubility of each complex ion is a linear function of pH, the solubility diagram can be obtained by plotting the logarithmic molar concentrations calculated from the values of the equilibrium constants and solubility products for hydroxides, carbonates, and hydroxyapatite. The optimum pH condition for the formation of single phase $Ca_{10-x}(HPO_4)_x(PO_4)_{6-x}(OH)_{2-x}(x=0)$ powder in $Ca-PO_4-H_2O$ system at $25^{\circ}C$ was estimated as $10.5{\pm}0.5$ through the theoretical consideration. The HAp powder dried at $80^{\circ}C$ showed a fine agglomerated particles with a size of 75 nm. The HAp powder calcined at $1,000^{\circ}C$ consisted of nearly homogeneous particles with a size of 450 nm. Even though the dried HAp particles consisted of agglomeration, mechanical properties were superior due to fine microstructure after sintering.