• Title/Summary/Keyword: HAS-2

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Kinetic Characterization of Brain Distribution for KR-31378 in Rats

  • Kim, Ji-Hye;Shim, Chang-Koo;Chung, Suk-Jae
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.421.2-421.2
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    • 2002
  • Recent studies show that KR-31378 [(2S.3SAR)-N"-cyano-N-(6-amino-3A-dihydro-3-hydroxy-2-methyl-2-dimethoxymethyl-2H-benzopyran-4-yl)-N${\cdots}$-benzylguanidine] has the neuroprotective effect as evidenced by the limitation of the size of infarct of the ischemia-reperfusion injury after an administration of KR-31378. In the literature. however. kinetics of KR-31378 distribution into the brain has not been systematically studied. (omitted)

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A Study on the Spatial Peculiarity of the Residential Environment - Centering around with the changes of the space of housing in the rural and fishing villages (주거환경의 공간적 특성에 관한 연구 - 농.어촌 주거공간의 변용를 중심으로 -)

  • 양택훈
    • Journal of the Korean housing association
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    • v.2 no.2
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    • pp.21-33
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    • 1991
  • In veiw of the results that the spatial peculiarity of the residential environment has been analyzed through the investigation of live on the change and use of the space of housing in the village of Bongsung, which is a traditional farming village of Cheju Island, and in the village of Hamo, which is a traditional fishing village of Cheju Island, a traditional constitution of space strongly remains in the village of Bongsungwhose family composition has been reductionized and implified, on the other side a tendency of extension or remodelling has been strongly appeared as well as a plot planning or a loose form has been appeared in the village of Hamo whose famiIy composition has been simplified and diversified and whose style of living has been also diversified, so the tianditional style which the yard has been surrounded with a stone wall has not remained. In the generation of 1970, a tendency to maintain the tranditional living style, to simply change for application, or to change for holding fast to the tradition was appeared, and the space of housing has been changed for the advanced modernization of life pattern since the generation of 1980. However, the traditional custom of life is continued.

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A Design of HAS-160 Processor for Smartcard Application (스마트카드용 HAS-160 프로세서 설계)

  • Kim, Hae-ju;Shin, Kyung-Wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.10a
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    • pp.913-916
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    • 2009
  • This paper describes a hardware design of hash processor which implements HAS-160 algorithm adopted as a Korean standard. To achieve a high-speed operation with small-area, the arithmetic operation is implemented using a hybrid structure of 5:3 and 3:2 carry-save adders and a carry-select adder. The HAS-160 processor synthesized with $0.35-{\mu}m$ CMOS cell library has 17,600 gates. It computes a 160-bit hash code from a message block of 512 bits in 82 clock cycles, and has 312 Mbps throughput at 50 MHz@3.3-V clock frequency.

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Study on the Validity and Reliability of MMDQ (Moos Menstrual Distress Questionnaire) among Middle School Students (중학생을 대상으로 한 Moos 월경증상 척도의 타당도와 신뢰도 검증)

  • Kim, Hae-Won;Kwon, Mi-Kyoung
    • Korean Parent-Child Health Journal
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    • v.7 no.2
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    • pp.111-120
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    • 2004
  • Purpose: This study was done to test the validity and reliability of the MMDQ for middle school students. Method: A convenience sample of 318 middle school students were asked to complete the MMDQ which consisted of 37 items and data were collected from May to June, 2004. Result: 1. Six factors for MMDQ (except insomnia, finally 36 items) were extracted through the principal component analysis with varimax rotation, and these contributed 56.7% of the variance in the total score. All 36 items in the scale loaded above .37 on one of 6 factors. 2. Factor 1 has 7 items, factor 2 has 9 items, factor 3 has 8 items, factor 4 has 5 items, factor 5 has 4 items, and factor 6 has 3 items. 3. Cronbach's alpha coefficient for internal consistency of MMDQ was .946 for the total 37 items and .88, .86, .88, .81, .70, .61 for the six factors in that order. Conclusion: MMDQ was identified its adequacy as PMS measurement tool for middle aged students in Korea. In further study, these factors would be confirmed across different samples and across different methods of data collection.

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Study on Body Proportion Using Body Indexes of Mongolian Men and Women in 20's (몽골 20대 남녀의 지수치를 이용한 인체 프로포션 연구)

  • Im, Soon
    • Journal of the Korea Fashion and Costume Design Association
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    • v.14 no.2
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    • pp.89-100
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    • 2012
  • The purpose of this research is to compare the body proportion of the Mongolian and Korean men and women in their 20' s by comparing the characteristics of the body type that uses the body indexes, in order to provide the base data for the increased fit of the apparels. The results are as follows. 1) Histogram of the Rohrer' s Index for the Mongolian men and women in their 20s was examined. the Mongolian men, normal body type took up 48.0% while small body type comprised 50.0% and obese body type comprised 2.0%. the Mongolian women, normal body type comprised 61.5%, small body type comprised 22.1% and obese body type comprised 16.4%. 2) The body proportion of Korean men has 1:1.62 with upper body and low body part on a waist basis, and Mongolian men has 1:1.65. Thus Mongolian men has longer pan of lower body than Korean men. 3) Mongolian women has longer part of lower body and has higher rates of hip height, crotch height, knee height than Korean women. Mongolian women has high rate of hip line and calf length. 4) As a result comparison using the body index of Mongolian and Korean women (bust thickness/ bust width, waist thickness / waist width, hip thickness / hip width, when regarding the height as 100 ), it was found that Mongolian women are flatter than korean women.

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Effects of Yangkyuksanhawtang on the Allergic Contact Dermatitis (양격산화탕(凉隔散化湯)이 Allergy성(性) 접촉피부염(接觸皮膚炎)에 미치는 영향(影響))

  • Cho, Se-Wang
    • Korean Journal of Korean Medical Institute of Dermatology and Aesthetics
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    • v.1 no.1
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    • pp.16-40
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    • 2005
  • Objective : To study the effectiveness of Yangkyuksanhawtang against Allergic Contact Dermatitis I observed the change of cutaneous shape, histochemistry, immunohistochemistry, and the distribution of apoptotic cells. materials and methods : I divided 4-month-old rats into three groups of 10, which are a contrastive group of having applied Acetone olive oil only, ACD group to have intentionally activated Allergic Contact Dermatitis by DNCB and YST group to give medication of Yangkyuksanhawtang extract. And I observed each group of mice after 24, 48 and 72 hours. results : 1. With the result of Contact hypersensitivity assay, YST group shows appreciably less ear swelling than ACD group. 2. Comparing YST and ACD groups to each other regarding general change of skin, YST group shows less hyperplasia of epidermis, less migration of inflammatory cells and less damage of epidermis than ACD group. 3. Regarding the change of collagen fiber, ACD group has appeared to be low in number of collagen fiber while YST shows similarity with the contrastive group. 4. In dermis YST group has showed lower number of mastocyte than ACD group and is granulated type. 5. In dermis YST group has showed less MAC-1, IL-1 , $IL-2R-\;{\alpha}$ G, ICAM-1 and VCAM-1 than ACD group. 6. The distribution of apoptotic cells has appeared littler in YST group than in ACD 7. Among signal molecule of apoptosis Bcl-2 has distributed more in YST group than ACD group and Bax and Fas has distributed less in YST group than ACD group.

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The characteristics of mineral hydrate insulation material using activated cement prepared from pilot plant activation system

  • Seo, Sung Kwan;Chu, Yong Sik;Kim, Tae Yeon;Kim, Yoo
    • Journal of Ceramic Processing Research
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    • v.19 no.5
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    • pp.428-433
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    • 2018
  • In this study, using the pilot plant activation system, the activated cement has been manufactured and then applied to the manufacturing process of mineral hydrate insulating material. The fineness of the activated cement is controlled at $5,000cm^2/g$ and $7,500cm^2/g$ and the features of mineral hydrate insulating material, using OPC and the activated cement for each degree of fineness, has been analyzed. As the result of analyzing the crystal habit of the manufactured mineral hydrate insulting material, it is analyzed that the main crystal phase of specimen is tobermorite and some quartz peak has been detected. As the degree of fineness of the activated cement increases, the height of bubble of slurry increases as well, whereas the tendency for the density character to decrease has been detected. Along with it, as the density character decreases, the compression strength has decreases, whereas the tendency for the thermal characteristic to increases has been detected. The main features of mineral hydrate insulating material, using the activated cement with the fineness of $7,500cm^2/g$, the compression strength of 0.36 MPa, and the thermal conductivity of $0.044W/m{\cdot}K$, presents the excellent features as insulation.

Capturing research trends in structural health monitoring using bibliometric analysis

  • Yeom, Jaesun;Jeong, Seunghoo;Woo, Han-Gyun;Sim, Sung-Han
    • Smart Structures and Systems
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    • v.29 no.2
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    • pp.361-374
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    • 2022
  • As civil infrastructure has continued to age worldwide, its structural integrity has been threatened owing to material deteriorations and continual loadings from the external environment. Structural Health Monitoring (SHM) has emerged as a cost-efficient method for ensuring structural safety and durability. As SHM research has gradually addressed an increasing number of structure-related problems, it has become difficult to understand the changing research topic trends. Although previous review papers have analyzed research trends on specific SHM topics, these studies have faced challenges in providing (1) consistent insights regarding macroscopic SHM research trends, (2) empirical evidence for research topic changes in overall SHM fields, and (3) methodological validations for the insights. To overcome these challenges, this study proposes a framework tailored to capturing the trends of research topics in SHM through a bibliometric and network analysis. The framework is applied to track SHM research topics over 15 years by identifying both quantitative and relational changes in the author keywords provided from representative SHM journals. The results of this study confirm that overall SHM research has become diversified and multi-disciplinary. Especially, the rapidly growing research topics are tightly related to applying machine learning and computer vision techniques to solve SHM-related issues. In addition, the research topic network indicates that damage detection and vibration control have been both steadily and actively studied in SHM research.

X-Ray and NMR Studies of Vanadium(V)-Nitrilotriacetate Complex (바나듐(V)-니크릴로트리아세테이트 착물의 X-선 및 핵자기공명 연구)

  • Lee, Man-Ho;Jeong, Woo-Won
    • Analytical Science and Technology
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    • v.10 no.3
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    • pp.196-202
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    • 1997
  • New vanadium(V) complex, $(NH_4)_2[VO_2NTA]$, has been synthesized and its structure has been determined by solution and solid-state NMR spectroscopies as well as X-ray crystallography. The unit cell of the monoclinic crystals contains four complexes with $a=6.923(1){\AA}$, $b=8.824(2){\AA}$, $c=19.218(11){\AA}$ and ${\beta}=91.60(3)^{\circ}$ in the space group of $P2_1/n$. The $[VO_2NTA]^{2-}$ anion has distorted octahedral geometry with cis-$VO_2$ moiety. It is confirmed that the octahedral geometry is retained in both of solution and solid-state complexes.

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A New Model for the Reduced Form of Purple Acid Phosphatase: Structure and Properties of $[Fe_2BPLMP(OAc)_2](BPh_4)_2$

  • 임선화;이진호;이강봉;강성주;허남휘;Jang, Ho G.
    • Bulletin of the Korean Chemical Society
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    • v.19 no.6
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    • pp.654-660
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    • 1998
  • $[Fe^{II}Fe^{III}BPLMP(OAc)_2](BPh_4)_2$ (1), a new model for the reduced form of the purple acid phosphatases, has been synthesized by using a dinucleating ligand, 2,6-bis[((2-pyridylmethyl)(6-methyl-2-pyridylmethyl)amino) methyl]-4-methylphenol (HBPLMP). Complex I has been characterized by X-ray diffraction method as having (μ-phenoxo)bis(acetato)diiron core. Complex 1 was crystallized in the monoclinic space group C2/c with the following cell parameters: a=41.620(6) Å, b=14.020(3) Å, c=27.007(4) Å, β=90.60(2)°, and Z=8. The iron centers in the complex 1 are ordered as indicated by the difference in the Fe-O bond lengths which match well with typical $Fe^{III}-O\; and\; Fe^{II}-O$ bond lengths. Complex 1 has been studied by electronic spectral, NMR, EPR, SQUID, and electochemical methods. Complex 1 exhibits strong bands at 592 nm, 1380 nm in $CH_3CN$ (ε = 1.0 × 103 , 3.0 × 102). These are assigned to $phenolate-to-Fe^{III}$ and intervalence charge-transfer transitions, respectively. Its NMR spectrum exhibits sharp isotropically shifted resonances, which number half of those expected for a valence-trapped species, indicating that electron transfer between $Fe^{II}\;and\;Fe^{III}$ centers is faster than NMR time scale. This complex undergoes quasireversible one-electron redox processes. The $Fe^{III}_2/Fe^{II}Fe^{III}\;and\;Fe^{II}Fe^{III}/Fe^{II}_2$ redox couples are at 0.655 and -0.085 V vs SCE, respectively. It has $K_{comp}=3.3{\times}10^{12}$ representing that BPLMP/bis(acetate) ligand combination stabilizes a mixed-valence $Fe^{II}Fe^{III}$ complex in the air. Complex 1 exhibits a broad EPR signal centered near g=1.55 which is a characteristic feature of the antiferromagnetically coupled high-spin $Fe^{II}Fe^{III}$ system $(S_{total}=1/2)$. This is consistent with the magnetic susceptibility study showing the weak antiferromagnetic coupling $(J= - 4.6\;cm^{-1},\; H= - 2JS_1{\cdot}S2)$ between $Fe^{II}\; and \;Fe^{III}$center.