• Title/Summary/Keyword: Gynecology department

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Monochorionic Triamniotic Triplet Pregnancy Following Assisted Reproductive Technology and Radiofrequency Ablation for Selective Reduction

  • Lee, Jeong-Heon;Oh, Su-Hyun;Hong, Ah-Reum;Jeong, Young-Ju;Cho, Sung-Nam;Cho, Dong-Hyu
    • Perinatology
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    • v.29 no.4
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    • pp.180-184
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    • 2018
  • In assisted reproductive techniques, monozygotic twinning is not influenced by the trial of reducing the number of embryos transferred. We present extremely rare case of monochorionic triamniotic triplet pregnancy following in vitro fertilization and two-embryo transfer. During the first trimester, the crucial ultrasound findings of monochorionic triamniotic triplet pregnancy are three distinct amniotic sacs forming a triangle or ipsilon zone within a single chorionic cavity. After prudential counseling about the potential risk of a monochorionic triamniotic triplet pregnancy with the patient, selective reduction of two fetuses via radiofrequency ablation was performed. We report a case of selective reduction for monochorionic triamniotic triplet pregnancy using radiofrequency ablation at 12 weeks' gestation and obstetric progression after radiofrequency ablation was uneventful until 20 weeks' gestation.

Insulin Resistance in Obese and Non-obese Patients with Polycystic Ovarian Syndrome (다낭성 난소 증후군 환자에서 비만군과 비비만군에서의 인슐린 저항성)

  • Lim, Y.K.;Lee, B.S.;Cho, E.J.;Cha, D.H.;Park, W.I.;Park, K.H.;Cho, D.J.;Lee, K.;Song, C.H.;Lee, E.J.
    • Clinical and Experimental Reproductive Medicine
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    • v.21 no.1
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    • pp.83-88
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    • 1994
  • This study was designed to investigate the relationship between insulin resistance and obesity in the pathogenesis of polycystic ovarian syndrome(PCO). Twenty-two women with PCO, of whom thirteen were non-obese with body mass index(BMI, kg/$m^2$) of <25 and nine were obese with BMI${\geq}$25 were studied. Eight non-obese control women and seven obese control women were studied. Serum concentrations of testosterone, lutenizing hormone(LH)/follicle-stimulating hormone(FSH) ratio, and insulin-like growth factor I (IGF-I) were found to be significantly higher(P<0.05) in PCO women compared with control women, which clearly is not related to obesity. Serum glucose, insulin, and C-peptide levels were measured during a 2-hour oral glucose tolerance test(OGTT). Non-obese and obese women with PCO both(P<0.05) compared with control women demonstrated significant hyperinsulinemia after OGTT. The degree of hyperinsulinemia was found to be significantly higher in the obese women with PCO compared with the non-obese women with PCO. We concluded that obesity may contribute to hyperinsulinemia, however may not playa central role in the pathogenesis of PCO.

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