• 화약ㆍ발파
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• 제11권2호
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• pp.60-68
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• 1993

서울지하철 제1, 2, 3, 4호선의 운행에 따른 소음 및 진동 발생은 인접 주거지역 주민들에게 공해 문제를 야기시켜 각종의 피해를 유발하고 있는 실정이다 그러나 현재 그 피해의 범위를 객관적으로 밝힐 수 있는 자료나지침이 없기 때문에 적절한 대책을 강구할 수가 없다. 따라서 본 조사를 통해 밝혀진 소음자료를 토대로 서울지하철 제1기 지상간의 지하철 차륜 통 과시 방출되는 소음레벨의 거리 별 분포 및 방출특성 그리고 각 노선별 비교 등과, 또 지하철 소음의 평가기준 및 평가방법과 현재 실용 가능한 방지대책을 제시하여 지하철 소음문제의 -반적인 처리지침으로 활용코져 한다. 본 조사 결과 제1호선 및 3호선은 소음레벨이 60dB(A) 미만으로 문제가 없고 소음공해 문제노선은 2호선 및 4호선의 일부 지상노출 구간으로 밝혀졌다. 이들 지역의 피선범위는 2호선의 경우 노선중심에서 50m 이내이고, 4호선의 경우 25m 이내로 이들 지점에서 각각 70dB(A)의 소음도를 기록하고 있다. 그리고 주민의 피해 호소율과 소음도 및 분포거리의 관계는 다음과 같이 밝혀졌다. 즉 80dB(A) 이상에서 강력한 집단민원이 발생하였고, 70-80dB(A)에서 간헐적인 피해호소를 하고 있었으며, 이들 값의 분포범위는 전자의 경우 고가구간에서 25m이내 철교구간에서 12.5m이내 그리고 철교 양구간에서 약 l00m이내이고, 후자의 경우 고가, 옹벽(U-Type) 및 철교구간에서 각각 50m이내이고, 철교량의 경우만 280m이내를 보이고 있다. 상기의 조사결과로부터 서울지하철의 일반적인 소음현황을 파악할 수 있어 지하철소음의 문제점을 개선하는데 필요한 자료로 활용할 수 있을 것으로 사료된다.

• 대한소아치과학회지
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• 제31권1호
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• pp.85-91
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• 2004

연구목적은 복합레진 중합 광원에 따른 치수강 온도 변화를 관찰하는 것이었다. 연구에 사용된 광중합기는 일반 플라즈마아크 광중합기, 저발열 플라즈마 아크 광중합기, 저출력 할로겐 광중합기, 저출력 LED 광중합기, 고출력 LED 광중합기의 다섯 개이었다. K-type thermocouple 온도계를 사용하여, 중합기 light guide tip에서의 온도를 측정하고, 잔존 상아질 두께가 1mm가 되도록 형성한 유구치 와동에 상아질 접착제만 도포한 군, ionomer glass를 함유한 base 또는 calcium hydroxide를 함유한 base를 0.5mm두께로 이장한 군에서 각각 레진 충전 전과 후의 치수강내 온도를 측정하였다. 중합기 light guide tip에서 측정한 온도는 일반 플라즈마가 $52.94^{\circ}C$로 가장 높았고, 저출력 LED가 $26.14^{\circ}C$로서 가장 낮았다. 레진충전 전의 치수강내 온도는 고출력 LED가 $41.60{\sim}43.34^{\circ}C$로 가장 높았고, 저출력 LED는 $36.50{\sim}36.76^{\circ}C$로서 가장 낮았다. 레진 충전 후의 치수강내 온도는 고출력 LED가 $40.22{\sim}40.94^{\circ}C$로 가장 높았고, 저발열 플라즈마와 저출력 LED는 온도 상승이 없었다. Base의 사용은 부분적인 열 차단 효과가 있었다.

• 정보관리학회지
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• 제27권1호
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• pp.229-248
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• 2010

대학에서 연구가 중요한 활동으로 주목을 받게 되면서 대학도서관에서도 연구지원 역할이 강조되고 있다. 이 연구에서는 북미 및 국내 60개 대학의 디지털도서관 홈페이지에서 온라인상으로 연구지원 가이드를 제공하는 현황을 조사하여 13개의 주요 내용유형을 분석하였고 이를 기반으로 하여 대학도서관이 연구지원 가이드 내용을 구성하는데 고려해야 할 5개의 주요 영역을 제시하였다. 또한 연구지원 가이드가 온라인상으로 제공되는 방식과 가이드를 통해 사서와 이용자가 소통하는 방식을 분석하였다. 연구지원 가이드를 제작, 제공하는 주체는 사서이며 대학도서관의 사서 역할은 향후 정보를 제공하는 역할에서 이용자를 위한 정보를 생산하는 역할로 확장될 것으로 예측된다.

• 한국수정란이식학회지
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• 제12권1호
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• pp.111-116
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• 1997

The present study was carried out to produce in vitro fertilized embryos with immature follicular oocytes collected by transvaginal aspiration from Holstein cows. A simple aspiration apparatus consists of two stainless steel tubes, an inner tube (needle holder; 1.2cmdiameter, 55cm long) and an outer tube (1.5cm diameter, 4Scm long), and a hand-operated vacuum pump was used. Under epidural anesthesia, the needle guide was passed into the vagina of the cow to a point next to the cervix. An ovary was placed against the wall of the vagina over the end of the aspiration needle by rectal manipulation. As the needlepassed into the ovary, an assistant was asked to apply vacuum(l00mrnHg) and the ovary was manipulated back and forth in all directions over the needle. When all sites of the ovary was aspirated, the needle was withdrawn and the needle guide was moved to the other side of ovary and the procedure was repeated. When the oocyte aspiration procedure was finished, collected fluid was transported to laboratory. Oocytes surrounded with at least 1 layer of cumulus cells were matured, fertilized and cultured in vitro. The results were as follows; Ninety seven oocytes were collected by transvaginal aspiration from seventeen Holstein cows(5.7 /head). The number of oocytes surrounded with at least 1 layer of cumulus cells were 60(61.9%). Following in vitro maturation, fertilization and culture, the cleavage and development rate to morula+blastocyst were 83.3% and 30.0%, respectively. From this study, transferable in vitro fertilized embryos could be produced with imma- ture follicular oocytes collected by transvaginal aspiration from Holstein cows using a simple aspiration apparatus.

• 소성∙가공
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• 제20권1호
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• pp.5-10
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• 2011

The main objective of the present study is to predict the process window of injection-compression molding corresponding to the capability of an injection machine for fabricating 7 inch LGP. The open distance and volume filled after injection stage were found to be two important factors that affect critical requirements such as flow length, injection pressure and clamping force for the process. Process window for the key factors was also predicted by response surface method. As a result, predicted process window for open distance and volume filled after injection stage satisfying the critical requirement with a given injection machine was in the range of 60 ~ 75%, and 104.00 ~ 104.25%, respectively.

• Journal of Magnetics
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• 제17권1호
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• pp.56-60
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• 2012

This paper presents an analysis and experiment of the flat coil actuator with shorted turn. The flat coil actuator is widely used in high precision products because it has no friction between the moving coil and the guide. A shorted turn and a center pole are placed into the flat coil actuator in order to reduce the inductance of the coil and improve the initial response when the actuator is voltage-driven. Enhanced dynamic performance of the flat coil actuator with shorted turn was demonstrated by simulation and experiment.

• 한국의학물리학회지:의학물리
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• 제8권2호
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• pp.67-76
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• 1997

본 연구에서는 유방암 진단용 감마카메라 제작 시에 고려되어야 하는 섬광체의 크기와 섬광체 면의 적절한 표면처리가 카메라의 민감도와 위치 분해능에 미치는 영향을 연구하기 위하여 섬광의 광학적 특성을 몬테카를로(Monte Carlo) 시뮬레이션 방법을 이용하여 고찰하였다. 섬광체는 NaI(TI) 결정체로 크기가 60 mm $\times$ 60 mm $\times$ 6 mm이며, 발생한 섬광이 광전자증배관의 광음극에 도달할 때까지를 시뮬레이션 하였다. 섬광체 표면 처리를(5가지 : Ground,. Polished, Metal-0.95RC(반사계수), Polished-0.98RC, Painted-0.98RC) 변화시켜 민감도를 계산하였다. 섬광체와 광전자증배관 (photomultiplier tube, PMT)의 접합면에 사용되는 물질의 굴절률 변화에 따른 민감도와 NaI(TI) 섬광체 창으로 많이 사용되고 있는 유리의 두께 변화에 따른 민감도를 조사하였다. 또한 섬광 결정체의 내인성 위치 분해능(intrinsic position resolution)을 섬광이 발생된 후 섬광 퍼짐(light spread) 정도를 시뮬레이션 함으로써 고찰하였다. 감마선의 입사면을 각각 Ground, Polished, Metal-0.95RC, Polished-0.98RC, Painted-0.98RC로 표면처리 하였을 때 민감도가 70.9%, 73.9%, 78.6%, 80.1%, 85.2%로 나타나 Painted-0.98RC일 때 민감도가 가장 우수하였다. 섬광체와 광전자증배관의 접합에 사용된 물질의 굴절률이 증가할수록 민감도가 증가하였으며 매질이 두꺼울수록 민감도는 저하되었다. 디자인된 검출기의 내인성 위치분해능은 수직, 수평 방향으로 약 1.2 mm로 예측되었다. 이 연구에서는 감마카메라의 성능에 직접적인 영향을 미치는 NaI (Tl)-PMT의 민감도와 위치 분해능을 몬테카를로 시뮬레이션을 통해 예견할 수 있었으며, 본 연구결과 NaI(TI)-PMT를 이용한 검출기가 고민감도ㆍ고해상력이 요구되는 유방암 진단용 소형 감마카메라 제작에 적합하다고 판단된다.

• Korean Journal of Radiology
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• 제21권7호
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• pp.812-828
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• 2020

Objective: To provide an evidence-based guide for the MRI interpretation of complete tumor response after neoadjuvant chemoradiation therapy (CRT) for rectal cancer using visual assessment on T2-weighted imaging (T2) and diffusion-weighted imaging (DWI). Materials and Methods: PubMed MEDLINE, EMBASE, and Cochrane Library were searched on November 28, 2019 to identify articles on the following issues: 1) sensitivity and specificity of T2 or DWI for diagnosing pathologic complete response (pCR) and the criteria for MRI diagnosis; 2) MRI alone vs. MRI combined with other test(s) in sensitivity and specificity for pCR; and 3) tests to select patients for the watch-and-wait management. Eligible articles were selected according to meticulous criteria and were synthesized. Results: Of 1615 article candidates, 55 eligible articles (for all three issues combined) were identified. Combined T2 and DWI performed better than T2 alone, with a meta-analytic summary sensitivity of 0.62 (95% confidence interval [CI], 0.43-0.77; I² = 80.60) and summary specificity of 0.89 (95% CI, 0.80-0.94; I² = 92.61) for diagnosing pCR. The criteria for the complete response on T2 in most studies had the commonality of remarkable tumor decrease to the absence of mass-like or nodular intermediate signal, although somewhat varied, as follows: (near) normalization of the wall; regular, thin, hypointense scar in the luminal side with (near) normal-appearance or homogeneous intermediate signal in the underlying wall; and hypointense thickening of the wall. The criteria on DWI were the absence of a hyperintense signal at high b-value (≥ 800 sec/mm²) in most studies. The specific algorithm to combine T2 and DWI was obscure in half of the studies. MRI combined with endoscopy was the most utilized means to select patients for the watch-and-wait management despite a lack of strong evidence to guide and support a multi-test approach. Conclusion: This systematic review and meta-analysis provide an evidence-based practical guide for MRI assessment of complete tumor response after CRT for rectal cancer.

• 약학회지
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• 제53권1호
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• pp.25-33
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• 2009

Metabolic syndrome is increasing nowadays and one of causes is obesity. Therefore prevention and treatment of obesity is very important to decrease of Metabolic syndrome. However currently many pharmacotherapy for obesity are popular in Korea and it may be dangerous. The aim of this study is to evaluate the purpose and relevance of obese treatment in two areas (capital & local) of Korea and suggest to guide for the right directions of pharmacotherapy in obesity treatment. We selected and surveyed 90 patients (88 females, 2 males, age of $23{\sim}60$) at random who received a prescription after consulting with a doctor at several clinics of Cheongju-area and Seoul-area, from May thru June, 2007. And we evaluated their prescriptions. In results, only 26.7% were obese (13.3%, 2325), most 73.3% patients were normal (65.6%, 18.5$m^2$). The purpose of treatment was for appearance (38.9%), health (41.1%) or both (18.9%, p<0.01). 94% patients had the past history of obese treatment. Prescriptions were consisted of CNS stimulant, anticonvulsants, antidepressant, laxatives, diuretics, or antianxietics. Obese treatment is very important for health to prevent disease such as Metabolic Syndrome. However it should not be abused. In conclusion, some patients of obese treatment is not relevant to obesity and pharmacist role is important to guide them for the right directions in obesity treatment.

• 대한한의학회지
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• 제21권4호
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• pp.16-25
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• 2000

Objective : Acupuncture and Radix Astragali aqua-acupuncture stimuli have long been used to cure human diseases. However, the exact physiological and biochemical mechanisms involved remain undiscovered. Thus, many attempts have been made to show the scientific mechanisms involved. The effects of acupuncture and Radix Astragali aqua-acupuncture, which was known to date, as follow; effective circulation of body blood system and proliferation of leucocytes. Methods : In this study, we have applied acupuncture and Radix Astragali aqua-acupuncture stimuli to mouse on Sinsuhyul, a stimulative point of oriental medicine, to see effects on the expression of cytokine $IL-1{\beta}$. Mice were treated with lipopolysaccharide(LPS) for inflammation induction and then reverse transcriptase-polymerase chain reaction (RT-PCR) using each primer set were performed to trace the amounts of mRNA. Results : 1. $IL-1{\beta}$ was not expressed in LPS-nontreated mice at 15 to 60 min after acupuncture-stimuli. However, expression occurred after 3hrs. 2. $IL-1{\beta}$ was specifically expressed in LPS-treated mice at 30 min after acupuncture-stimuli. 3. $IL-1{\beta}$ was expressed in LPS-nontreated mice at 30 min after Radix Astragali aqua-acupuncture stimuli, however, not expressed at 60, 180 min. 4. $IL-1{\beta}$ was gradually expressed in LPS-treated mice at 15 to 180 min after Radix Astragali aqua-acupuncture stimuli. Conclusions : $IL-1{\beta}$ in LPS-treated mice was more effective than that of LPS-nontreated mice. We are now in the process of elucidating the immunological action mechanism of acupuncture and Radix Astragali aqua-acupuncture stimuli. And cytokine $IL-1{\beta}$ can be used not only as a basis of the effects of acupuncture and Radix Astragali aqua-acupuncture but also as a diagnosis guide through the immunological actions of those.