• The Journal of Pediatrics of Korean Medicine
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• v.23 no.1
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• pp.141-158
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• 2009

Objectives The purpose of this study is to find out the effect of KyungOcGogamibang(KOGE) on the growth of rats. Methods First of all, we divided male Sprague-Dawley rats into 4 groups(KOGE1, KOGE2, KOGE3 and control group). Then KOGE1, KOGE2 and KOGE3 groups were administered with KOGE water extracts once a day at a dosage of 250, 500, 1,000mg/kg respectively for 3 weeks. The control group was administered with normal saline in the same manner. We measured the rat's body weight, amount of body weight increased, length of femur, serum GH, serum IGF-Ⅰ, serum TSH and serum testosterone after each week of administration. Results 1. There were significant changes of the rat's body weight, the length of the femur, the level of GH, IGF-Ⅰand TSH in KOGE1 groups. 2. There were significant changes of the rat's body weight, the length of the femur, the level of IGF-Ⅰand TSH in KOGE2 groups. 3. There were significant changes of the rat's body weight, the length of the femur, the level of IGF-Ⅰand TSH in KOGE3 groups. Conclusions According to the results above, rat in KOGE group have been increased their body weight, length of femur, serum GH, serum IGF-1 compared to the control group. This study shows that groups of KOGE have an effect on promoting the growth, thus it is expected to treat growth problems for children.

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.2
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• pp.19-34
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• 2006

Objective : The purpose of this study is to find out the effect of Jowonsangamibang(JWS) on the growth of rats. Methods : First of all, we divided male Sprague-Dawley rats into 4 groups(J1, J2, J3 and sham group). Then J1, J2 and J3 groups were administered with JWS water extracts(JWSE) once a day at a dosage 250, 500, 1,000mg/kg respectively for 3 weeks. The sham group was administered with normal saline in the same manner. And we measured body weight, amount of body weight increased, length of femur, serum GH, serum IGF-I, serum TSH and serum testosterone after each week. Results : There were no significant changes of body weight, the level of GH, TSH, and testosterone in J1, J2 and J3 groups. The change of body weight gained was increased significantly in the J3 group compared with the sham group after 1, 2 and 3 weeks. The length of the femur was increased significantly in the J2 group after 1 week and in the J3 group after 3 weeks compared with the sham group. The level of IGF-I in the serum was increased significantly in J1, J3 after 1 week compared with the sham group. Conclusion : According to the results above, JWS increased body weight, length of femur, serum GH, serum IGF-1 compared with the sham group. This study shows that JWS has an effect on promoting the growth of rats, thus it's expected to treat of growth delay in children.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.17 no.2
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• pp.104-111
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• 2014

Purpose: To evaluate safety, gastrointestinal tolerance, and growth of a new experimental starter formula (NESF) fortified with lutein, prebiotics, probiotics, nucleotides and beta-carotene, fed to infants within the first months of life. Methods: This was a non-randomized, open, uncontrolled study conducted from December 2010 to May 2011. Twenty-three healthy infants aged 10 days to 2 months old were enrolled. Outcomes included gastrointestinal tolerance, physical growth and safety. Prior to the initiation of the trial, the Scientific Research Institute of Nutrition of the Russian Academy of Medical Sciences confirmed that the NESF met all safety and nutritional parameters. Results: NESF was well tolerated. The majority of infants fed this formula passed semi-liquid, yellow or yellow-brown. The mean stool frequency/day was $2.5{\pm}0.4$ on study-day 14 and $1.8{\pm}0.5$ on study-day 28. The mean daily weight gain was $30.9{\pm}3.8$ grams and the mean length gain during the 28 days of follow up was $3.1{\pm}0.8cm$, corresponding to the average physical growth normally seen in the first months of life in Russian infants. Six children left the study: one refused to drink the formula, one left the study as parents changed residence; and one child's parents have recalled their informed consent due to adverse event unrelated to the product. Three infants presented adverse events possibly related to the product (rash; colic and abdominal pain; constipation). Seventeen infants completed the trial. Conclusion: This study demonstrated that lutein-fortified formula is safe, well-tolerated and supported physical growth of evaluated infants.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.20 no.1
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• pp.41-46
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• 2017

Purpose: Vitamin D deficiency is common in Crohn disease (CD). The aim of the study was to examine the prevalence of vitamin D deficiency and evaluate the association between vitamin D status and growth outcome in Korean pediatric CD patients. Methods: In this retrospective study, 17 children younger than 18 years old diagnosed with CD were enrolled and their serum 25-hydroxy vitamin D (25[OH]D) was checked between 2011 and 2015. We categorized the patients into two groups, Group 1 and Group 2. Group 1 included patients with serum 25(OH)D levels below 10 ng/mL, and Group 2 was for patients with a 25(OH)D serum levels between 10 ng/mL and 30 ng/mL. The z-scores for height (Htz), weight (Wtz), and body mass index (BMIz) were measured at baseline, 6 months, and 12 months. Results: The mean serum 25(OH)D levels of the total 65 CD patients and 17 enrolled patients were $15.64{\pm}6.9ng/mL$ and $13.1{\pm}5.1ng/mL$, respectively. There was no correlation at the beginning of the study between vitamin D level and growth parameters (Htz, Wtz, BMIz) or other variables including laboratory data and Pediatric Crohn Disease Activity Index. The Htz, Wtz, and BMIz in Group 1 showed no significant improvement at 6 months and 12 months follow-up. In Group 2, Wtz and BMIz showed significant improvements sustained until 12 months of follow-up. Htz showed no significant improvement at 6 months but there was significant improvement at 12 months. Conclusion: It seems that baseline vitamin D status affects growth outcome in pediatric CD.

• Korean Journal of Human Ecology
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• v.9 no.1
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• pp.85-95
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• 2000

This study is about psychological growth environment and style of loving among 88 men and 128 women in university students. The results of this study are following. First, the result of psychological growth environment and style of loving among university students show that men have expectation for the achievement and encouragement more than women as they are moved up the higher grade. Largely when they are moved up the higher grade, they respect individual opinion and have responsibility for their behaviors. Also they tend to have the cooperation in their home. So as they are moved up the higher grade, they have the independent spirit from their parents and are prepared to adaptability for social life. Second, the result of the style of loving show that men tend to fall in love easily and also pursuit altruistic and romantic love. According to being moved up the higher grade, they have the actual attitude in the intercourse with the other sex. Third, the result of psychological growth environment show that persons who want to come true their desire more need the friendly love, altruistic love and love for amusement. Contrarily, when they don't communicate each other in their home, they tend to pursuit love for amusement. When they have the higher level of communication and cooperation in their psychological environment, they tend to pursuit for logical love. When they have expectation of mutual role, mutual intimacy, love and respect, they pursuit friendly love. Also through they are adapt for style of social behaviors in each other, they acpuire the love and respect between family members. And they pursuit friendly love through it.

• Korean Journal of Health Education and Promotion
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• v.9 no.1
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• pp.88-102
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• 1992

The exact estimation of physical growth by Obesity level has important meaning to the health care and evaluation on adolescent girls. So this study tried to clear the relationship between weight and body fat by using data for the height, weight of 124 elementary school children and high school student in Seoul. Then this study tried to show the physical growth pattern and various characteristics by Obesity level by using longitudinal for the height, weight of 1113 high school students in Seoul, and it also tried to show what influencing factors on the physical growth of this aged population. The result could be summarized as follows. 1. The relationship between weight and body fat(%) has 0.81475(r) at age 9 and 0.69361(r) at age 18. Also the relationship between weight and lean body muscle(LBM %) has -0.81470(r) at age 9 and -0.64729(r) at age 18. 2. The weakness, normal and obesity groups were classified by Obesity level. In case of weakness group showed the very low Obesity level at age 8 to 11, in case of obesity group showed the high Obesity level at age 15 to 18. Also Rohrer index was decreasing tendency up to age 12 in weakness group and increasing tendency over age 14 in obesity group. 3. When the height and weight growth pattern was compared, height growth was superior to weight growth at age 9 to 14.5 in normal group. But weight growth was inferior to height growth at age 9 to 14.5 in normal group. In obesity group, weight growth was superior to height growth at age 7 to 18. On the other hand the height growth of weakness group was superior to the normal group and the obesity group except age 11 to 12. 4. On height velocity curve by PHV age obesity group showed the most growth amount per year(9.00Cm/yr), and the next is normal group(8.77Cm/yr), weakness group(8.70Cm/yr). Then the difference between PHV age and PWV age was within 1 year in these three groups. 5. In these three groups, height velocity curve by menarcheal age showed the PHV before 2~3 years of menarcheal age. And weight velocity curve by menarcheal age showed the remarkable PWV before 1 year of menarcheal age.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.2 no.1
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• pp.21-29
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• 1999

Purpose: The aims of this study are to examine clinical characteristics, patterns of medical care utilization, and factors which determine medical care utilization of elementary school children with recurrent abdominal pain (RAP), to find posssible factors influencing the onset and the course of the disorder. Method: We performed questionnaires in Kwangju on children from two primary schools from June,1 1998 to June 30 and carried out statistical analysis. Result: 1) Total number of questionnaires were 1417. 715 were male and 702 were female and the ratio of male to female was 1.02:1. Average age was 10.3 years. 2) 268 children had RAP (18.9%), boys 132 (18.4%), girls136 (19.2%). 3) The duration of the pain within 10 minutes was 68.5%. 178 children with RAP (66.3%) visited the doctor. The utilization pattern of medical facilities of the pupils with RAP; the most frequently utilized medical facility was pediatrics (35.2%) and the order ran as internal medicine (31.5%), and pharmacy (29.25). The utilization pattern of medical facilities for the older students; the utilization rate of pediatrics decreased, but internal medicine increased. The major factors affecting the selection of the medical facility were geographic accessibility, kindness of the personnel, good results and traffic convenience. 4) Symptoms which were accompanied with abdominal pain were headache (44.5%), chest pain (28.2%), dizziness (26.6%), vomiting (9%), and 119 children (44.5%) had no accompanied symptoms. 5) In 95 children (35.3%) abdominal pain, occured at postprandial time, in 55 children (20.5%) before meal and in 39 children (14.7%) at school. The highest incidence rate of RAP was observed on Monday (21.4%), and the lowest on Saturday (8.7%). 6) The most frequent involved part of the abdomen was periumbrical area (38%) and the order ran as epigastrium and suprapubic area. The most frequent characteristics of abdominal pain were burning pain (36.9%) and the order ran as dull, cramping and colicky pain. Conclusion: RAP is a frequent disease entitiy in children. Too many times children with RAP are treated by other departments instead of Pediatrics. A child has a peculiar growth and development which is different to those from an adult with advancing years. So, it is necessary to choose special medical care and an adequate medical facility.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.3 no.1
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• pp.7-18
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• 1973

The authors have taken the x-ray films of carpal bone and orthopantomographs in Korean children to research the degree of ossification of carpal bone, that of calcification of tooth in jaw bone, the eruption rate of tooth, and the completion rate of apical foramen, and have compared the bone age and tooth age. We have gained a series of intersting conclusions to dare to report. 1. The ossification of carpal bone and the growth of tooth had processed proportionally to each other. 2. Both the bone age and tooth age were earlier in the female than in the male. 3. The completion of tooth crown formation and that of tooth root formation had processed proportionally to each other, and the general tendency of process was the earliest in the mandibular first molar and the latest in the second molar. 4. The eruption of tooth was the earliest in the mandibular first molar. The other teeth had erupted in the following orders: the central incisor, the lateral incisor, the first premolar, the second premolar, the canine and the second molar.

• The Journal of Pediatrics of Korean Medicine
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• v.22 no.2
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• pp.69-80
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• 2008

Objectives : The purpose of this study was to evaluate the correlation of 3 methods of bone age measurements. Methods : 102 children(49 boys, 53 girls) were involved in this study. We measured the height, weight and bone age based when they visited for the first time. We measured bone age using BoneAge of Sunlight Co.,Ltd. Two of the bone age measurement methods, Greulich-Pyle and Tanner-Whitehouse, were used to analyze the left dorsopalmar hand-wrist radiographs of 102 children who visited in Department of Pediatrics, O O University Oriental Hospital. This study was designed to investigate the correlation of the bone age between two methods. Results : The bone ages were related with age, height, weight and BMI according to this study(P<0.01). Each bone age assessment method had statistically significant correlation to each other(P<0.01). Conclusions : The ultrasound transonic velocity of inferior radiocarpal joint will become a sufficient diagnostic tool of bone age assessment if measurement error can be minimized by proper effort.

• The korean journal of orthodontics
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• v.52 no.4
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• pp.308-312
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• 2022

Since the emergence of neonatal infant orthodontics for treatments of cleft lip and palate with or without Robin sequence (RS) in Europe in the 1950s, advancements in design and scope of its application have been remarkable. As the first institution to adopt orthodontic airway plate (OAP) treatment in the United States in 2019, we saw a need for innovation of the original design to streamline the most labor-intensive and time-consuming aspects of OAP utilization. A solution is introduced using a systematic split expansion mechanism to re-size the OAP periodically to accommodate the neonate's maxillary growth. To date, seven RS patients have received this modified treatment protocol at our institution. Each patient completed full treatment using only one OAP. This innovative utilization method is aptly named the split orthodontic airway plate (S-OAP). Details of the S-OAP and its modifications from conventional OAP are reported.