• 정보관리학회지
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• 제22권1호
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• pp.191-208
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• 2005

새로운 주제의 탐지를 위한 여러 접근법들을 지식 구조 표현 방법 중 하나인 디스크립터의 부여 및 갱신 과정에 적용하였다. 새로운 주제 탐지는, 특히 특정 학문 분야에서 새로운 주제의 출현 및 성장으로 인하여 지식구조상의 변화가 발생하는 경우에, 기존의 색인어로는 이를 표현할 수 없거나 표현상의 제한이 따르는 문제를 해결하는 데 응용할 수 있다. 실험 결과, 정보학 내에서 긍정적 측면의 변화가 발생한 것으로 식별된 신흥 주제들은 상당수가 서로 밀접하게 연관되어 있으면서 동시에 성장${\cdot}$발전의 단계에 있는 주제임을 확인하였다. 또한, 새로운 주제 탐지를 통한 후보 디스크립터 리스트의 사용이 색인자의 색인작업을 지원하는 효율적인 도구가 될 수 있다는 가능성을 보여 주었다. 특히, 적절한 디스크립터의 선정과 부여를 위한 후보 디스크립터 리스트의 제공은 색인작업의 효율성과 정확성을 향상시키는 데 기여할 수 있을 것이다.

• 디자인학연구
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• 제12권4호
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• pp.109-118
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• 1999

역사적으로 볼 때, 지난 100여 년 간 자동차 개발의 경향은 기술적인 성능 위주로의 경쟁이 주도하여 왔다고 할 수 있다. 특히 첨단 전자 산업의 급속한 성장에 의한 자동차 기술력의 향상은 단기간에 걸쳐 괄목할만한 결과를 가져온 것이다. 초창기부터 고급차를 생산하는 일부 유명 제조 사에서 현재의 신흥 자동차 제조 사 까지 승용차를 위주로 한 개발기술 능력은 한계에 이를 만큼 매우 근소한 차이로 좁혀져 왔다. 따라서 이제는 자동차 선택의 기준에 디자인이 큰 몫을 하게되었다. 최근의 자동차 스타일의 경향은 보편적인 삶의 질의 향상에 따른 소비자의 다양한 욕구에 만족할 수 있는 개성 있는 디자인으로 변화되고 있다. 따라서, RV, SUV, MPV 등의 자동차가 등장하는가 하면, 각 차종별로 독특한 파생 모델이 나타나고 있다. 본 연구에서는 차세대 개념의 새로운 소형 SUV형 자동차 디자인에 대한 컨셉카 연구를 시도하였다. 리서치에서부터 최종 하드모델까지 자동차 디자인 프로세스에 의거 진행한 전과정은 대우자동차의 디자인 연구소에서 진행되었다. 특히 젊은 연령층이 쉽게 소유할 수 있도록 값싸고 개성 있는 새로운 카테고리의 자동차 개념을 스타일화 하였으며 고객의 반응도를 조사 분석하여 차후 경 SUV 자동차 개발에 참조될 수 있도록 하였다.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제2권8호
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• pp.335-342
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• 2013

네트워크의 고속화와 다양한 서비스의 등장으로 오늘날의 네트워크 트래픽은 복잡 다양해지고 있다. 효율적인 네트워크 관리를 위해서 QoS, SLA와 같은 정책을 적용하기 위해서는 트래픽 분석 중에서도 응용 트래픽 분류의 중요성이 크다. 현재까지 트래픽 분류에 관한 연구가 활발히 진행되어 왔는데 최근에는 플로우의 통계 정보를 이용한 트래픽 분류 방법론이 많이 연구되고 있다. 하지만 플로우의 통계 정보를 이용한 트래픽 분류 방법론에는 필히 고려해야 할 여러 문제점이 있다. 본 논문에서는 정답지 트래픽 분석을 통해 통계 정보 기반 트래픽 분석 방법론의 해결해야 하는 문제점들을 분석하고 그 해결방안에 대해 제안한다. 통계 정보 기반 트래픽 분석 방법론에서 필히 해결해야 할 문제점은 총 네 가지로 Feature들의 거리 측정 방법과 대표값 추출 방법, TCP 세션의 이상동작, 그리고 패킷 별 가중치이다. 제안하는 방법은 선정한 통계 시그니쳐 기반 트래픽 분석 시스템을 이용한 학내 망에서의 실험을 통해 그 성능을 검증한다.

• Journal of Korean Vacuum Science & Technology
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• 제2권2호
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• pp.63-77
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• 1998

The oxidation of NiAl(110) was investigated in the temperature regime between 300K and 1300 K using LEED (low energy electron diffraction), TPD (temperature programmed desorption) and HREELS (high resolution electron energy loss spectroscopy). The adsorption of N2O and O2 up to reconstructions. Stepwise annealing of the oxygen-saturated sample from 600 K to 1300K in UHV (ultra-high vacuum,) results in firstly the onset of randomly oriented then finally fairly well-ordered. 5 ${\AA}$ Al2O3 film with quasi-hexagonal periodicity. Ordered thicker oxide films of 18-30 ${\AA}$ seem to be grown on this interfacial oxide layer by direct oxidation of sample at elevated temperature between 1150 and 1300 K because of the LEED pattern consisting of new broad hexagonal spots and the previous 5 ${\AA}$ spots. Although the periodicity of surface oxygen arrays shows no significant change from an hexagonal close-packing, the O-O distance changes from ∼3.0 ${\AA}$ film to ∼2.9 ${\AA}$ for thicker oxides. with the appearance of Auger parameter, for the 5${\AA}$ film can be described better as an interfacial oxide layer. The observation of three symmetric phonon peaks can be also a supporting evidence for this phase assignment since thicker oxide films on the Same Ni2Al3(110) show somewhat different phonon structure much closer to that of the ${\gamma}$-Al2O3. The adsorption/desorption of methanol further proves the preparation of less-defective and/or oxygen-terminated Al2O3 films showing ordered phase transitions with the change of oxide thickness between 5 ${\AA}$ to 30 ${\AA}$.

• 한국임상수의학회지
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• 제25권6호
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• pp.458-465
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• 2008

The purpose of this study is to characterize canine mesenchymal stem cells (MSCs) derived from bone marrow (BM) for use in research on the applications of stem cells in canine models of development, physiology, and disease. BM was harvested antemortem by aspiration from the greater tubercle of the humerus of 30 normal beagle dogs. Canine BM-derived MSCs were isolated according to methods developed for other species and were characterized based on their morphology, growth traits, cell-surface antigen profiles, differentiation repertoire, immunocytochemistry results, and neurotrophic factor expression in vitro. The canine MSCs exhibited a fibroblast-like morphology with a polygonal or spindle-shaped appearance and long processes; further, their cell-surface antigen profiles were similar to those of their counterparts in other species such as rodents and humans. The canine MSCs could differentiate into osteocytes and neurons on incubation with appropriate induction media. RT-PCR analysis revealed that these cells expressed NGF, bFGF, SDF-1, and VEGF. This study demonstrated that isolating canine MSCs from BM, stem-cell technology can be applied to a large variety of organ dysfunctions caused by degenerative diseases and injuries in dogs. Furthermore, our results indicated that canine MSCs constitutively secrete endogenous factors that enhance neurogenesis and angiogenesis. Therefore, these cells are potentially useful for treating dogs affected with various neurodegenerative diseases and spinal-cord injuries.

• 한국임상수의학회지
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• 제34권2호
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• pp.126-131
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• 2017

This study investigated the incidence rate of umbilical hernia (UH) in pig farms and examined the effect of using them as breeding pigs on reproductive traits. The occurrence of UH ranged from 0.1% to 3.0% in pig farms investigated. UH pigs were found in almost all farms except for a single farm in Jeju Island. Spontaneously occurring UH pigs were selected and used for cross breeding tests. UH-related crosses and their progeny showed significant (P < 0.05) differences in gestation period, the numbers of piglets born and alive, and body weights at birth and $21^{st}$ day comparing to those of the control population. UH-related crosses showed longer gestation period, reduced numbers of piglets, and lighter body weights than those from the control population. Interestingly, reduced number of piglets was about one fourth, suggesting that UH inheritance might play a critical role as a lethal gene during embryogenesis. In addition, UH incidence rate in UH-related crosses was significantly (P < 0.05) higher than that in the control except for UH-cross3. However, in the progeny of control cross, a pig also had UH appearance, indicating that porcine UH might be inherited in recessive inheritance mode. Taken together, the results of this study indicate that UH is one of recessively inherited genetic defect that occurs at ordinary times in pig farms, suggesting that the use of UH animals as sire and/or dam may lead to economic losses due to increased gestation period, reduced numbers of piglets born and alive, and lower growth rates after birth of pigs.

• 한국약용작물학회지
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• 제25권4호
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• pp.224-230
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• 2017

Background: The current regulations regarding the storage of medicinal herbs do not define the storage temperature; instead, but the only requirement is that the plastic bags used for storing the medicinal herbs should be tightly sealed during storage. The practice of storing medicinal herbs at room temperature ($28^{\circ}C$), causes many problems, including growth of insect pests on the stored medicinal herbs. Thus, it is necessary to understand the effect of insect pests on the quality of medicinal herbs stored at room temperature ($28^{\circ}C$) for the improving the relevant regulations. Methods and Results: Cnidium rhizome and Angelica radix were infested with Lasioderma serricorne F. adults and incubated at $28^{\circ}C$ for 2.5 and 5 months. The population of L. serricorne was established rapidly, and left many holes, cadavers, and feces on the stored medicinal herbs, thereby greatly damaging the product appearance and hygiene. In addition, active ingredients of the medicinal herbs were significantly decreased, probably reducing their medicinal quality as well. Conclusions: These results indicate that the current regulations are not sufficient to prevent the establishment of storage insect pests and guarantee the quality and hygiene of stored medicinal herbs. Therefore, it is necessary to devise proper storage protocols and upgrade the current relevant regulations to maintain the quality of medicinal herbs during storage.

• Korean Journal of Acupuncture
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• 제29권1호
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• pp.17-22
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• 2012

Objectives : The purpose of this study is to discuss the diagnostic classification of the traditional medicine for pilosis, and the hair removal treatments in traditional medicine and its clinical application. Backgrounds : In recent years, appearance and beauty have become main interest that have positioned in the medical area. In clinical Korean medicine, a variety of methods such as moxibustion, superficial bleeding, multiple microneedling, facial meridian massage, herbal medicine facial pack, laser acupuncture, and intense pulsed light (IPL) have been applied. Methods and Results : Pilosis, a condition of abnormal hair growth, is stated for the first time in the publication, [Pathogenesis and Manifestations of All Diseases] by Chao Yuan-fang in 610 A.D. It shows that pilosis has been recognised as a disease for ages in Asia. Reviewing several publications, we found multiple approaches to pilosis were already existed in korean medicine. They include internal medicinal classification and its' medications. Acupuncture treatments also focused on regulation of radical causes and superficial removal of abnormal hairs. Specific treatments includes body and ear acupuncture, ear acupressure, hypodermic acupuncture, hypodermic acupuncture injection, laser acupuncture treatment. Physical and chemical methods of hair removal were widely invented. we resulted that significant scientific approaches to pilosis are under way in the korean medical field, and found a variety of medical treatments such as herbal medicines and dermatological methods. Conclusions : Hair removal treatments for pilosis in traditional medicine has a long history. Combined with advanced modern technology it can achieve greater advance in cosmetology.

• Molecules and Cells
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• 제21권1호
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• pp.112-120
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• 2006

It has been suggested that defective interfering (DI) RNA contributes to the persistence of Japanese encephalitis virus (JEV). In this study, we characterized molecular and biological aspects of the DI RNA and its relation to viral persistence. We identified a homologous DI virus intimately associated with JEV persistence in Vero cells. The production of DI RNA during undiluted serial passages of JEV coincided with the appearance of cells refractory to acute infection with JEV. We also established a Vero cell clone with a persistent JEV infection in which the DI RNA coreplicated efficiently at the expense of helper virus. The infectious virus yield of the clone fluctuated during its growth depending upon the amount of DI RNA accumulated in the previous replication cycle. Identification of the corresponding negative-sense RNA of the DI RNA indicated that the DI RNA functioned as a replication unit. Most of the DI RNA molecules retained their open reading frames despite a large deletion, encompassing most of the prM, the entire E, and the 5' half of the NS1 gene. Taken together, these observations suggest that the generation of homologous DI RNA during successive JEV acute infections in Vero cells probably participates actively in persistent JEV infection.

• 한국식품조리과학회지
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• 제10권3호
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• pp.254-259
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• 1994

Meat provides high quality proteins, lipids, minerals and vitamins. The meat protein is especially high in essential amino acids that are crucial for human health, growth & development and for the formation of enzymes, hormones and antibodies. Relatively cheap and nutritionally sound vegetable proteins that are similar to animal proteins are being developed to replace the animal proteins in texture, nutrition and food characteristics. In this study a nutritionally sound meat lipid replacing food Oatrim that has been produced by converting oat starch into maltodextrin by ${\alpha}$-amylase, have been partially substituted for beef and general component analysis, texture measurement and sensory tests have been conducted. The results are 1. Water content of the non-treated (0% treated) was 67.1% and the treated (10% treated) was 77%. The treated showed better water holding capacity. 2. Protein content of the non-treated was 21.2 g/100 g; the 4% treated, 18.4 g/100 g; the 6% treated, 18.2 g/100 g; the 8% treated, 17.2 g/100g; and the 10% treated, 16.0 g/100 g. The protein content tended significant. 3. Amino acid analysis results showed that glutamic acid content was the highest in Oatrim and as its amino acid make up is exellent, it is valuable as a fine low fat protein food. 4. Sensory tests show that the increased Oatrim content increased the appearance quality but food characteristics were high only in the 4% and 6% treated groups, indicating that the replacement ratio should not exceed 10%. 5. Texture measurement analysis results show that the higher the replacement content, lower the springness, cohesiveness, hardness, chewiness and gumminess, resulting in relatively soft overall texture. However, in order to better the food characteristics, more studies must be continuously done, and so by being able to increase vegetable substitution over meat, it may be able to contribute to the prevention of adult disease.