• 제목/요약/키워드: Growth and development

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Protein variation and involvement of insulin-like growth factor during embryonic development in the olive flounder Paralichthys olivaceus

  • Kim, Kang-Woong;Nam, Taek Jeong;Choi, Youn Hee
    • Fisheries and Aquatic Sciences
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    • 제21권2호
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    • pp.4.1-4.5
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    • 2018
  • Insulin-like growth factors (IGFs), along with IGF-binding protein and IGF receptor, are well-known regulators in the growth and survival of vertebrates. In this study, we investigated the involvement of IGFs and protein variation during embryonic development of the olive flounder (Paralichthys olivaceus). Morphological stages were divided into six main developments as blastula, gastrula, cephalization, cranial regionalization, tail lift, and hatch. During embryonic development, protein variation was investigated using sodium dodecyl sulfate-polyacrylamide gel electrophoresis and electrospray ionization quadrupole time-of-flight mass spectrometry/mass spectrometry. In addition, the mechanism of signaling of IGF-I receptor was examined using immuno-blot analysis. We found marked changes in protein expression at four stages of embryonic development and identified proteins as belonging to the vitellogenin 2 family. As development progresses, expression of IGF-II, phosphotyrosine, and phospho-Akt increased, while expression of growth factor receptor-bound protein 2 (GRB2) and one of guanine-nucleotide-binding proteins (Ras) decreased. These results provide basic information on the IGF system in the embryonic development of the olive flounder.

Growth Responses of seven Intestinal Bacteria Against Phellodendron amurense Root-Derived Materials

  • Kim, Min-Jeong;Lee, Sang-Hyun;Cho, Jang-Hee;Kim, Moo-Key;Lee, Hoi-Seon
    • Journal of Microbiology and Biotechnology
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    • 제13권4호
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    • pp.522-528
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    • 2003
  • The growth responses of Phellodendron amurense root-derived materials against seven intestinal bacteria were examined, using an impregnated paper disk agar diffusion method and spectrometric method under $O_2$-free condition. The biologically active constituent of the P. amurense root extract was characterized as berberine chloride ($C_{20}H_{18}NO_{41}Cl$) using various spectroscopic analyses. The growth responses varied depending on the bacterial strain, chemicals, and dose tested. At 1 mg/disk, berberine chloride strongly inhibited the growth of Clostridium perfringens, and moderately inhibited the growth of Escherichia coli and Streptococcus mutans without any adverse effects on the growth of three lactic acid-bacteria (Bifidobacterium bifidum, B. longum, and Lactobacillus acidophilus). The structure-activity relationship revealed that berberine chloride exhibited more growth-inhibiting activity against C. perfringens, E. coli, and S. mutans than berberine iodide and berberine sulfate. These results, therefore, indicate that the growth-inhibiting activity of the three berberines was much more pronounced as chloridated analogue than iodided and sulphated analogues. As for the morphological effect caused by 1 mg/disk of berberine chloride, most strains of C. perfringens were damaged and killed, indicating that berberine chloride showed a strong inhibition against C. perfringens. As naturally occurring growth-inhibiting agents, the P. amurense root-derived materials described could be useful as a preventive agent against diseases caused by harmful intestinal bacteria such as clostridia.

Growth-Promoting Effects of Vegetable Extracts on Selected Human Lactic Acid Bacteria

  • Kim, Moo-Key;Kim, Byung-Su;Baek, Bong-Rea;Shin, Dong-Hwa;Lee, Hoi-Seon
    • Preventive Nutrition and Food Science
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    • 제6권3호
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    • pp.192-196
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    • 2001
  • Ethanol extracts from 36 vegetable samples were assayed for their growth-promoting effects on Bifidobacterium bifidum, B. longum, and Lactobacillus casei The growth-promoting effects varied according to bacterial strain and vegetable species. In modified Gy rgy broth, extracts of Lactuca sativa, Lycopersicon esculentum and L escutentum var. cerasiforme exhibited strong growth-promoting responses toward B. longum, and significant and strong growth- promoting response toward B. bifidum was observed in extracts of Actinidia arguta, Allium cepa, A. sativum, Brassica campestris subsp. napus vats. pekinensis, Capsicum frutescens, Daucus carota var. sativa, L sativa, 1. esculentum and L. esculentum var. cerasforme, Nelumbo nucifera, Cucurbita moschata, Lackca sativa var. capitata, and Rubus coreanus. For L casei, extracts of A. fshlosum, A. hberosum, Cichorium intbus, Cucurbita moschat\ulcorner Ipomoea batatas, 1. sativa var. capitata, L. esculentum, P. brachycarpa, Raphanus sativus, R. coreanus, and S. melongena strongly enhanced the growth of this bacteria. In modified Gy rgy broth, the promoting effect was most pronounced with B. bifidum and L. casei among lactic acid bacteria used. In MRS broth, A. arguta, A. cepa, A. sativum, B. campestris subsp. napus var. pekinensis, C. frutescens, and D. carota var. sativa L. satiw var. capitata, and R. coreanus strongly enhanced the growth of B. bifidum, Growth of B. longum was strongly affected by the addition of extracts from L. sativa var. capitata. For L casei, moderate growth-promoting responses were observed in 9 vegetable extracts. The promoting effect in MRS broth was most pronounced with B. bifidum among lactic acid bacteria used.

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효과적 개발정책에 관한 솔로우 모형의 함의에 대한 검증 (Testing Solow's Implications on the Effective Development Policy)

  • 정혁
    • KDI Journal of Economic Policy
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    • 제36권1호
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    • pp.107-126
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    • 2014
  • 신고전파 성장이론의 핵심은 자본투자라 할 수 있다. 솔로우는 이러한 자본축적을 통한 균형성장 경로에 안정성을 부여하는 기제로 수확체감의 원리를 제시한다. 이 핵심 명제는 지속가능하며 효과적인 개발정책에 자본축적을 통한 정상(定常) 상태 성장뿐 아니라 이행과도기 성장과정에 있어서 생산성의 중요성에 대해 중대한 함의를 가진다. 본 논문은 이러한 솔로우 모형의 함의를 뒷받침하는 근간이 되는 가정인 수확체감의 법칙에 대한 테스트를 위한 실증방법론을 제시하고 Penn World Tables 제8버전 데이터를 이용하여 자본축적 과정에 수확체감이 강하게 작용함을 확인하고, 이에 효과적 개발정책에 대한 솔로우 모형의 함의를 입증한다.

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Inclusive Innovation and Growth Based on a National Innovation System: Experience from China

  • Junfang, Zhang;Rong, Guo;Wei, Zhou
    • STI Policy Review
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    • 제3권2호
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    • pp.66-78
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    • 2012
  • China is becoming a global hot topic because of its rapid economic growth. However, the country show signs of not meeting the expectation of retaining its long-term industrial competitiveness and economic growth, especially with a widening rich-poor gap and natural resource exhaustion. Realizing inclusive growth requires study of an inclusive innovation solution. In this paper, we analyze the feasibility and development path of China's inclusive innovation based on the framework of a National Innovation System, identify examples of inclusive innovation in China, and seek to provide policy suggestions for China's future sustainable development.

선버들의 생장 특성 (Growth Characteristics of Salix nipponica)

  • 이팔홍;손성곤;김철수;오경환
    • 한국습지학회지
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    • 제4권2호
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    • pp.1-11
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    • 2002
  • The morphology, seed germination, and life history of Salix nipponica were investigated in the wetland of the Nam-River, Jinju, Gyeongsangnam-do, Korea from 2000 to 2001 to provide the basic data necessary for riverine ecosystem restoration through understanding the growth characteristics of Salix nipponica. Salix nipponica had stomata on only lower side and stomata type was paracytic. Salix nipponica produced many small and light seeds. The seed number per mature ament was 1599.4, seed mass of 0.04 mg, and fertilization rate of 66.1%. Seed germination was little affected by light. Germination rate was high and mean germination time was short Under flooding condition, seeds were germinated normally and were viable after as much as 14 days of flooding. But there were no differences under various water depths on germination rates. Tree age was closely correlated with more stem diameter than tree height and there was no difference of growth rate between male and female tree. Growth rate was most rapid for 2 to 3 years after germination, and length growth was almost stopped for more than 11 years even though mass growth was done. Besides even a second-year indivisual was flowered.

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Plant Growth-Promoting Rhizobacteria Stimulate Vegetative Growth and Asexual Reproduction of Kalanchoe daigremontiana

  • Park, Yong-Soon;Park, Kyungseok;Kloepper, Joseph W.;Ryu, Choong-Min
    • The Plant Pathology Journal
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    • 제31권3호
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    • pp.310-315
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    • 2015
  • Certain bacterial species associate with plant roots in soil. The plant growth-promoting rhizobacteria (PGPR) stimulate plant growth and yield in greenhouse and field. Here, we examined whether application of known bacilli PGPR strains stimulated growth and asexual reproduction in the succulent plant Kalanchoe daigremontiana. Four PGPR strains B. amyloliquefaciens IN937a, B. cereus BS107, B. pumilus INR7, and B. subtilis GB03 were applied to young plantlets by soil-drenching, and plant growth and development was monitored for three months. Aerial growth was significantly stimulated in PGPR-inoculated plants, which was observed as increases in plant height, shoot weight, and stem width. The stimulated growth influenced plant development by increasing the total number of leaves per plant. Treatment with bacilli also increased the total root biomass compared with that of control plants, and led to a 2-fold increase in asexual reproduction and plantlet formation on the leaf. Collectively, our results firstly demonstrate that Bacillus spp. promote vegetative development of K. daigremontiana, and the enhanced growth stimulates asexual reproduction and plantlet formation.

항구도시로서 동해시의 성장전망과 개발방향에 관한 연구 (A Study on the Growth Prospect and Development Direction of Donghae City as Port City)

  • 최장순
    • 한국농촌건축학회논문집
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    • 제8권1호
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    • pp.70-79
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    • 2006
  • This study deals with analysing the growth prospect and development direction of Donghae city with two international ports. To do so, it is progressed, firstly, to examine the general discovery about port since the late nineteenth century, secondly, to unfold it's theory with Mukho and Donghae port as Donghae city development element as the central figure, thirdly, to analyse Donghae city as the important place of traffic, the location of industry and the resource base in a spatial planning side.

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미숙아의 퇴원 후 영양 (Post-discharge Nutrition)

  • 김이경
    • Neonatal Medicine
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    • 제16권2호
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    • pp.131-136
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    • 2009
  • Preterm infants are frequently discharged from the hospital with growth retardation. Given the potentially lifelong effects of growth impairmnet during a critical time of development, considerable effort should be focused on improving growth after discharge. Growth monitoring must be based on regular measurements of weight, length, and head circumference to identify those preterm infants with poor growth that may need additional nutritional support. Although prior studies vary in design and the intervention used, the evidence supports the use of fortified formulas in formula-fed preterm infants after discharge. The situation for infants fed human milk is much less clear, it seems prudent to concentrate our efforts on the encouragement of breast-feeding in this population. Catch up growth may have many benefits, and may lead to improved development. However, its long-term metabolic consequences are currently unclear. Understanding the optimal means of providing nutrition after discharge is an ongoing process.

Salicylic Acid Counteracts Aluminum Stress-induced Growth and Biomass Yield Reduction in Medicago sativa L.

  • Rahman, Md. Atikur;Lee, Sang-Hoon;Song, Yowook;Ji, Hee Jung;Kim, Ki-Yong;Choi, Gi Jun;Lee, Ki-Won
    • 한국초지조사료학회지
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    • 제39권3호
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    • pp.153-157
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    • 2019
  • Salicylic acid (SA) is an essential plant growth regulator that functions as a signaling molecule in plants. The purpose of this study was to clarify how the exogenous application of SA counteracts aluminum stress-induced growth and biomass yield reduction in alfalfa exposed to aluminum (Al) stress. Two-week-old alfalfa seedlings were exposed to a combination of $AlCl_3$ ($0{\mu}M$, $50{\mu}M$ and $100{\mu}M$, respectively) and SA (0.1 mM) for 72 hours. We observed, Al stress-induced plant growth inhibition and forage yield reduction are Al stress-dependent manner. A significant reduction of plant height (42.0-52.9%), leaf relative water content (13.0-21.4%), root length (35.4-48.7%), shoot fresh weight (31.2-25.9%), root fresh weight (15.4-23.3%), shoot dry weight (12.7-22.2%), roots dry weight (47.3-53.5%), were observed in alfalfa. In contrast, SA alleviated the Al-stress and enhanced growth and biomass yield in alfalfa. This study provides useful information concerning the role of SA that counteracts aluminum stress-induced growth and yield reduction in alfalfa.