• Title/Summary/Keyword: Growth Support

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Characterization of Growth-supporting Factors Produced by Geobacillus toebii for the Commensal Thermophile Symbiobacterium toebii

  • Kim, Joong-Jae;Masui, Ryoji;Kuramitsu, Seiki;Seo, Jin-Ho;Kim, Kwang;Sung, Moon-Hee
    • Journal of Microbiology and Biotechnology
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    • v.18 no.3
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    • pp.490-496
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    • 2008
  • Symbiobacterium toebii is a commensal symbiotic thermophile that cannot grow without support from a partner bacterium. We investigated the properties of Symbiobacterium growth-supporting factors (SGSFs) produced by the partner bacterium Geobacillus toebii. SGSFs occurred in both the cell-free extract (CFE) and culture supernatant of G. toebii and might comprise multifarious materials because of their different biological properties. The heavy SGSF contained in the cytosolic component exhibited heat- and proteinase-sensitive proteinaceous properties and had a molecular mass of >50 kDa. In contrast, the light SGSF contained in the extracellular component exhibited heat-stable, proteinase-resistant, nonprotein properties and had a molecular mass of <10 kDa. Under morphological examination using light microscopy, S. toebii cultured with the culture supernatant of G. toebii was filamentous, whereas S. toebii cultured with the CFE of G. toebii was rod-shaped. These results strongly suggest that the SGSFs produced by G. toebii comprise two or more types that differ in their growth-supporting mechanisms, although all support the growth of S. toebii. Upon the examination of the distribution of SGSFs in other bacteria, both cytosolic and extracellular components of Geobacillus kaustophilus, Escherichia coli, and Bacillus subtilis had detectable growth-supporting effects for S. toebii, indicating that common SGSF materials are widely present in various bacterial strains.

Kinetic Analysis of CpG-Induced Mouse B Cell Growth and Ig Production

  • Kim, Young-Ha;Lee, Sang-Hoon;Yoo, Yung-Choon;Lee, Jung-Lim;Park, Jong-Hwan;Park, Seok-Rae
    • IMMUNE NETWORK
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    • v.12 no.3
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    • pp.89-95
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    • 2012
  • Immune cells express toll-like receptors (TLRs) and respond to molecular patterns of various pathogens. CpG motif in bacterial DNA activates innate and acquired immune systems through binding to TLR9 of immune cells. Several studies reported that CpG can directly regulate B cell activation, differentiation, and Ig production. However, the role of CpG in B cell growth and Ig production is not fully understood. In this study, we analyzed the effect of CpG on the kinetics of mouse B cell viability, proliferation, and Igs production. Overall, CpG enhanced mouse B cell growth and production of Igs in a dose-dependent manner. Unlike LPS, 100 nM CpG (high dose) did not support TGF-${\beta}1$-induced IgA and IgG2b production. Moreover, 100 nM CpG treatment abrogated either LPS-induced IgM or LPS/TGF-${\beta}1$-induced IgA and IgG2b production, although B cell growth was enhanced by CpG under the same culture conditions. We subsequently found that 10 nM CpG (low dose) is sufficient for B cell growth. Again, 10 nM CpG did not support TGF-${\beta}1$-induced IgA production but, interestingly enough, supported RA-induced IgA production. Further, 10 nM CpG, unlike 100 nM, neither abrogated the LPS/TGF-${\beta}1$- nor the LPS/RA-induced IgA production. Taken together, these results suggest that dose of CpG is critical in B cell growth and Igs production and the optimal dose of CpG cooperates with LPS in B cell activation and differentiation toward Igs production.

The Role of Corporate Social Responsibility for Sustainable Growth: An Exploratory Case Study on Auto Corporations (지속성장을 위한 사회적 책임(CSR)의 전략적 활용: 중국 내 자동차 기업에 대한 탐색적 사례연구)

  • Baek, Seoin;Kwon, Sang-Jib
    • Knowledge Management Research
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    • v.16 no.3
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    • pp.103-128
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    • 2015
  • This study sheds light on the role of corporate social responsibility in firms' growth by investigating how and what corporate social activities may flow down china auto industry market. This study results based on in-depth case studies from 5 international auto corporations suggest that positive diverse corporate social responsibility amplified that the influence of commitment to the customer on firm's brand loyalty and sustainable growth. The most important thing is that strategic corporate social responsibility activities including new venture creation support and national project program will have a positive influence on the firm's growth and brand reputation. We build on advanced solutions to examine the unique and joint activities of auto corporations based on china auto industry market and important factors affecting sustainable growth in auto corporations. Contributions and implication of this study for current and future corporate social responsibility research are discussed.

Effect of Polymer Coating on the Initial Microorganism Attachment and the Biofilm Growth (고분자 물질 도포가 미생물 부착과 생물막 성장에 미치는 영향)

  • 박영식;송승구
    • Journal of Environmental Health Sciences
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    • v.24 no.2
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    • pp.104-109
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    • 1998
  • The objective of this study was to examine the effect of polymer coating on the initial microorganism attachment and the biofilm growth. Such as nonion(polyacrylamine), anion(CMC-Na) and cation polymer coagulant(chitosan and PEI) were used for coating material of the support carrier(acryl plate). When polymer coagulant was coated with 5, 10, 20, 35, 50, 100 and 200 mg/l on the surface of acryl plate, initial microorganism attachment increased and optimum concentration for the attachment was 35 mg/l. Biofilm growth experiments were conducted with the substrate loading of 12.7gSCOD/$m^2\cdot$ day using RBC. The polymer coagulants such as CMC-Na, polyacrylamide, PEI and chitosan coating on the acryl plate facilitated the biofilm growth of microorganisms. Until the biofilm dry weight grows up to 0. 0038g/cm$^2$, biofilm growth on the plate coated with cation polymer like chitosan was better than that on the coated plate of nonion(polyacrylamine), anion(CMC-Na) polymer coagulant.

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Application of Growth Models for Pigs in Practice -Review-

  • van der Peet-Schwering, C.M.C.;den Hartog, L.A.;Vos, H.J.P.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.2
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    • pp.282-286
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    • 1999
  • Growth of pigs is influenced by many factors. To assist pig producers in the evaluation of alternative feeding and management strategies growth models have been developed. In the Netherlands the Technical Model Pigfeeding (TMV) is developed. This model predicts the influence of feed intake, feed composition, genotype, sex and climate on growth, body composition, gross margin and mineral excretion of healthy growing/finishing pigs. The purpose of TMV is to support information services, feed companies, researchers and students. In addition to providing accurate predictions, a model should also be user-friendly and wishes of the user should be taken into account to stimulate application of the model in practice. In this paper, the theoretical background of TMV and a methodology to stimulate application of models in practice will be described.

Effects of the Utilization of Non-Reciprocal Trade Preferences Offered by QUAD Countries on Economic Growth in Beneficiary Countries

  • SENA KIMM GNANGNON
    • KDI Journal of Economic Policy
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    • v.45 no.1
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    • pp.33-68
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    • 2023
  • The present article investigates empirically whether non-reciprocal trade preferences (NRTPs) offered by QUAD countries (Canada, the European Union, Japan, and the United States) to developing countries have helped to promote economic growth in the beneficiary countries. Two main blocks of NRTPs are considered here: Generalized System of Preferences (GSP) programs and other trade preferences programs. The analysis used a set of 90 beneficiary countries of NRTPs that are concurrently recipients of development aid over the period of 2002-2018. Using the two-step system generalized method of moments, the analysis indicated that while a higher degree of utilization of each of these two blocks of NRTPs has been associated with a high economic growth rate, development aid enhances this positive effect. This highlights the need for donors to support a development strategy based on the provision of both development aid and NRTPs if they are to help beneficiary countries to promote economic growth. Finally, when the positive economic growth effect of the utilization of NRTPs is higher, the result is a greater country's share of exports (under preferential tariffs) to QUAD countries out of their total merchandise exports.

Influencing Factors for Post-traumatic Growth in Patients with Breast Cancer (유방암 환자의 외상 후 성장 영향 요인)

  • Choi, Sung-Hee;Lee, Young-Whee
    • The Journal of the Korea Contents Association
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    • v.16 no.11
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    • pp.499-509
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    • 2016
  • This study was undertaken to investigate the factors that influence post-traumatic growth in patients with breast cancer. The study subjects were 100 outpatients with breast cancer who visited the outpatient clinic of a university hospital. The instruments used for this study were Korean Post-traumatic Inventory (K-PTGI), Modified Medical Outcomes Study Social Support Survey (mMOS-SS), Self-Efficacy Scale for Self-Management of Breast Cancer (SESSM-B) and Cancer Coping Questionnaire (CCQ). The data were analyzed by t-test, ANOVA, Pearson-correlation coefficient, and stepwise multiple regression using SPSS/WIN 21.0. The mean score of post-traumatic growth was $3.4{\pm}0.9$ out of 5. Post traumatic growth had statistically significant correlation with social support, breast cancer self-management self-efficacy, and coping behavior. In stepwise multiple regression analysis, post-traumatic growth was significantly influenced by therapeutic compliance related self-efficacy and positive reframing coping behavior and it was account for 29% of the total variance. These results suggest that these influencing factors should be considered in developing the nursing intervention to improve the post-traumatic growth in patient with breast cancer.

A Study on the Startup Growth Stage in Korea (스타트업 성장단계 구분에 대한 탐색적 연구)

  • Kim, Sunwoo;Kim, Kangmin
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.15 no.2
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    • pp.127-135
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    • 2020
  • The purpose of this paper is to classify individual startups by growth stage based on data-based quantitative criteria. This is to provide a basis for systematic support for government startups based on accurate statistics on the startup growth process. This startups were the TIPS (Tech Incubator Program for Startup) support company, which used a relatively reliable startup. We found seed money to complete MVP (Minimum Viable Product) within 1.5 years after establishment, verified PMF (Product-Market Fit) within 1 year, attracted Series A investment within 2.5 years after establishment, and successfully commercialized it. It attracted Series B investment for stable growth within 1.5 years (Series B investment within 4 years from start-up). The results of the study, the division of government programs that support stage-based startup commercialization, that is, within three years and within seven years of establishment, is significant to date. Three directions are suggested for future research. First, develop indicators for monitoring startup growth stages. Second, it continuously updates the annual changes and tracks the growth stages of individual startups. Third, we discover the successful growth law of technology-based startups by applying in-depth case analysis of successful startups to the model.

Biotic and Abiotic Effects on the Growth and Reproduction of Aristolochia contorta (생물 및 비생물적 요인이 쥐방울덩굴의 생육과 생식에 미치는 영향)

  • Park, Hyun Jun;Park, Hyekyung;Son, Ga Yeon;Nam, Bo Eun;Kim, Jae Geun
    • Journal of Wetlands Research
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    • v.22 no.2
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    • pp.113-120
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    • 2020
  • For the conservation of both Sericinus montela (vulnerable species by red book of Korea) and A. contorta, we investigated environmental factors affecting the growth and reproduction of Aristolochia contorta. We selected four A. contorta habitats at Gapyeong, Pyeongtaek, Cheongju, and Yeoju in Korea and surveyed community and habitat characteristics of companion species, herbivore appearance, support types, and soil physicochemical properties in July and October, 2018. Habitat environments and the growth and reproduction characteristics of A. contorta were different according to four habitats of different regions. In particular, the fastest growth speed and earliest flowering and fruiting were observed in Pyeongtaek. Growth of A. contorta in Cheongju and Yeoju were interrupted by aboveground damage from human disturbance. In this study, support types seemed to be important for growth speed of A. contorta. Flowering and fruiting timing were likely to be related to combined effects of soil cation contents and competitive and herbivore stresses. Therefore, providing effective support and reducing biological stress should be necessary for stable growth and proper flowering and fruiting timing of A. contorta. In addition, experimental evidence would be needed to figure out the effect of soil cation and biological stress on flowering and fruiting of A. contorta in detail.

Implementation of Complex Growth-environment Control System in Greenhouse (온실 복합생장환경 관제 시스템 구현)

  • Cho, Hyun Wook;Cho, Jong Sik;Park, In Gon;Seo, Beom Seok;Kim, Chan Woo;Shin, Chang Sun
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.7 no.1
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    • pp.1-9
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    • 2011
  • In this paper, Wireless sensor network technology applied to various greenhouse agro-industry items such as horticulture and local specialty etc., we was constructed automatic control system for optimum growth environment by measuring growth status and environmental change. existing monitoring systems of greenhouse gather information about growth environment depends on the temperature. but in this system, Can be efficient collection and control of information to construct wireless sensor network by growth measurement sensor and environment monitoring sensor inside of the greenhouse. The system is consists of sensor manager for information processing, an environment database that stores information collected from sensors, the GUI of show the greenhouse status, it gather soil and environment information to soil and environment(including weather) sensors, growth measurement sensor. In addition to support that soil information service shows the temperature, moisture, EC, ph of soil to user through the interaction of obtained data and Complex Growth Environment information service for quality and productivity can prevention and response by growth disease or disaster of greenhouse agro-industry items how temperature, humidity, illumination acquiring informationin greenhouse(strawberry, ginseng). To verify the executability of the system, constructing the complex growth environment measurement system using wireless sensor network in greenhouse and we confirmed that it is can provide our optimized growth environment information.