• Title/Summary/Keyword: Growth Response

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Mitogen-Activated Protein Kinase Kinase 3 Is Required for Regulation during Dark-Light Transition

  • Lee, Horim
    • Molecules and Cells
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    • v.38 no.7
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    • pp.651-656
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    • 2015
  • Plant growth and development are coordinately orchestrated by environmental cues and phytohormones. Light acts as a key environmental factor for fundamental plant growth and physiology through photosensory phytochromes and underlying molecular mechanisms. Although phytochromes are known to possess serine/threonine protein kinase activities, whether they trigger a signal transduction pathway via an intracellular protein kinase network remains unknown. In analyses of mitogen-activated protein kinase kinase (MAPKK, also called MKK) mutants, the mkk3 mutant has shown both a hypersensitive response in plant hormone gibberellin (GA) and a less sensitive response in red light signaling. Surprisingly, light-induced MAPK activation in wild-type (WT) seedlings and constitutive MAPK phosphorylation in dark-grown mkk3 mutant seedlings have also been found, respectively. Therefore, this study suggests that MKK3 acts in negative regulation in darkness and in light-induced MAPK activation during dark-light transition.

Proteomic Analysis of Coprinopsis cinerea under Conditions of Horizontal and Perpendicular Gravity

  • Kim, Ji-Su;Kwon, Young-Sang;Bae, Dong-Won;Kwak, Youn-Sig;Kwack, Yong-Bum
    • Mycobiology
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    • v.45 no.3
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    • pp.226-231
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    • 2017
  • Coprinopsis cinerea was employed to investigate the fungal response to gravity. Mycelium growth revealed a consistent growth pattern, irrespective of the direction of gravity (i.e., horizontal vs. perpendicular). However, the fruiting body grew in the direction opposite to that of gravity once the primordia had formed. For the proteomic analysis, only curved-stem samples were used. Fifty-one proteins were identified and classified into 13 groups according to function. The major functional groups were hydrolases and transferases (16%), signal transduction (15%), oxidoreductases and isomerases (11%), carbohydrate metabolism (9%), and transport (5%). To the best of our knowledge, this is the first report on a proteomic approach to evaluate the molecular response of C. cinerea to gravity.

Effect of Interleukin-2 Administration Route on Antitumor Response Against Subcutaneous Meth-A Tumor in Mice (마우스에 있어서 Interleukin -2의 투여방법이 Meth-A 종양세포에 대한 항암효과에 미치는 영향)

  • 권오덕
    • Journal of Veterinary Clinics
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    • v.17 no.2
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    • pp.311-315
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    • 2000
  • Recombinant interleukin-2 (IL-2) has been demonstated as an antineoplastic agent in mice and human, and the route of administration is important to IL-2-induced therapeutic responses. Therefore, the current experiment was undertaken to clarify the effect of IL-2 administration route on antitumor response against subcutaneous Meth-A tumor in mice. At the beginning of each experiment, normal BALB/c mice were injected subcutaneously with $5{\times}10^6$ Meth-A tumor cells. Beginning on day 7, experimental groups were treated with a 5-day course of IL-2 (intraperitoneal or subcutaneous injection of 30, 000 IU every 12 hours for 5 days). The result of this experiment revealed that Meth-A tumor grew progressively in control mice. Intraperitoneal IL-2 treatment decreased significantly tumor growth and prolonged survival, compared with control mice. Subcutaneous IL-2 treatment decreased significantly tumor growth until day 11 and tumor cells, grew progressively thereafter, but mice in this group survived longer than control mice.

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The Role of Gut Microbiota in Modulating Tumor Growth and Anticancer Agent Efficacy

  • Kim, Jaeho;Lee, Heung Kyu
    • Molecules and Cells
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    • v.44 no.5
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    • pp.356-362
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    • 2021
  • An increasing number of studies have revealed an interaction between gut microbiota and tumors. The enrichment of specific bacteria strains in the intestines has been found to modulate tumor growth and influence the mechanisms of tumor treatment. Various bacteria are involved in modulating the effects of chemotherapeutic drugs currently used to treat patients with cancer, and they affect not only gastrointestinal tract tumors but also distant organ tumors. In addition, changes in the gut microbiota are known to be involved in the antitumor immune response as well as the modulation of the intestinal immune system. As a result, the gut microbiota plays an important role in modulating the efficacy of immune checkpoint inhibitors. Therefore, gut microbiota could be considered as an adjuvant treatment option with other cancer treatment or as another marker for predicting treatment response. In this review, we examine how gut microbiota affects cancer treatments.

The Nexus Between Monetary Policy and Economic Growth: Evidence from Vietnam

  • NGUYEN, Hoang Chung
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.1
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    • pp.153-166
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    • 2022
  • The study estimates the Structured VAR and the Dynamic Stochastic General Equilibrium Model for the Vietnamese economy based on the new Keynesian model for small and open economies, with the output gap, inflation, policy interest rate, the Vietnamese exchange rate, and the inflation and interest rate in the United States. The paper aims to clarify the impulse response of the macro variables through their shocks. It offers to model the SVAR and DSGE processes, as well as describe why and how interest rate policy is important in the impulse response of macro variables like the output gap and inflation process. The study supports the central role of monetary policy by giving empirical evidence for the new Keynesian theory, according to which an interest rate shock causes the output gap to widen and inflation to decrease. Finally, the application of the DSGE model is becoming more and more popular in the State Bank of Viet Nam to improve its policy planning, analyzing, and forecasting policy towards sustainable and stable growth.

Response of Leaf Water Potential and Growth Characteristics to Irrigation Treatment in Soybean

  • Lee, Jeong-Hwa;Seong, Rak-Chun
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.48 no.2
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    • pp.81-88
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    • 2003
  • Soybeans [Glycine max (L.) Merr.] are frequently exposed to unfavorable environments during growing seasons and water is the most important factor limiting for the production system. The purpose of this study was to determine the leaf water potential changes by irrigation, and to evaluate the relationships of leaf water potential, growth and yield in soybeans. Three soybean cultivars, Hwangkeumkong, Shinpaldalkong 2, and Pungsannamulkong, were planted in growth chamber and field with irrigated treatments. Leaf water potential of three soybean cultivars was positively correlated with leaf water content during vegetative and reproductive growth stages in growth chamber and field experiments. Leaf water potentials measured for three soybean cultivars under growth chamber were higher than those of under field conditions. Higher leaf water potential with irrigated plots under field was observed compared to conventional plots during reproductive growth stages. Leaf water potentials of three soybean cultivars were continually decreased during reproductive growth stages under field and there was no significant difference among them. Number of leaves, leaf water content, pod dry weight, number of seeds and seed dry weight with irrigated plots were higher than those of conventional plots. The results of this study suggested that leaf water potential could be used as an important growth indicator during the growing season of soybean plants.

Growth Response to a GH-Autotransgenesis in Common Carp Cyprinus carpio

  • Noh, Choong-Hwan;Kim, Dong-Soo
    • Fisheries and Aquatic Sciences
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    • v.15 no.1
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    • pp.37-41
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    • 2012
  • Autotransgenic manipulation with a growth hormone (GH)-construct is a potential approach to improving the growth rates of farmed fish. Here, we present the generation of GH-autotransgenic common carp Cyprinus carpio carrying a transgene comprised of the carp homologous GH gene and a ${\beta}$-actin regulator. Autotransgenic carp showed similar viability to their non-transgenic siblings. Early growth characteristics of founder autotransgenic carp up to 50 days postfertilization were highly variable among individuals; i.e., some fish exhibited significant growth depression, while others showed dramatic acceleration of growth, achieving greater than sixfold increases in body weight relative to their non-transgenic counterparts. Stimulated growth performance became more notable with age and many transgenic individuals of the largest class reached 5 kg within 8 or 9 months, which is at least 10 times heavier than the average body weight of communally grown non-transgenics. Four of six founder transgenic males were successful in passing the transgene to their $F_1$ offspring with frequencies ranging from 19 to 36%. Growth stimulations were also persistent in all $F_1$ progeny groups examined.

Effects of Flavonoids on Pollen Tube Growth in Arabidopsis thaliana

  • Kim, Young-Soon;Song, Kyu-Sang;Cheong, Hyeon-Sook
    • Journal of Plant Biology
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    • v.39 no.4
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    • pp.273-278
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    • 1996
  • Arabidopsis mutants deficient in flavonoid and sinapate ester (tt4 and fah1-7, respectively) were evaluated in vivo and in vitro to study the possible role of flavonoid compounds in pollen tube growth. In vivo, we investigated pollen tube growth in the pistils of the mutants and wild type(Ler). The growth of pollen tubes was significantly different among the three genotypes. In the fal1-7 pistils, the tubes grew to a greater length relative to those of the wild type or tt4. To examine in vitro pollen tube growth, a solid medium was devised for pollen germination and subsequent growth. In vitro, the identical result was obtained; fahl-7 pollens developed the longest tubes and elongated most rapidly. Therefore, the growth response of pollen tubes to phenolic compounds was examined by adding quercetin or sinapate ester in various concentrations to the media. Quercetin enhanced both germination rate and tube growth in the pollens of the mutants and the wild type, especially in tt4. In contrast, sinapate ester inhibits pollen germination and pollen tube growth in three genotypes. These results suggest that flavonoids and related phenolic compounds have physiological role in the plant reproductive system.

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Panel Analysis of Relationship Between Regional Logistics Industry and Economic Growth in Korea (지역물류산업과 경제성장의 관계에 대한 패널분석)

  • Choi, Bong-Ho;Lee, Gi-Whan
    • Korea Trade Review
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    • v.44 no.2
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    • pp.173-188
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    • 2019
  • The purpose of this study is to investigate the causal relationship between the logistics industry and the economic growth in Korea, and to provide implications for the contribution of the logistics industry to economic growth. Unlike Previous Related Studies, we derive short-term and long-term effects through dynamic panel analysis such as panel Granger causality test and impulse response function estimation using panel vector error correction model. The results of the empirical analysis are as follows: Labor input of the logistics industry has the greatest positive impact on economic growth. And capital input and total sales of the logistics industry have a negative effect on economic growth. This means that Korea's logistics industry features labor-intensive growth. In addition, We have also found that the growth (sales) and capital input of the logistics industry have not yet had a direct positive impact on economic growth. Therefore, the results of this analysis provide implications for the direction of logistics industry policy to enhance contribution of the logistics industry to economic growth.

Effects of temperature and water management in rice fields on larval growth of Pantala flavescens (Odonata: Libellulidae)

  • Bosomtwe Augustine;Jinu Eo;Myung-Hyun Kim;Min-Kyeong Kim;Soon-Kun Choi;So-Jin Yeob;Jeong-Hwan Bang;Owusu Danquah Eric
    • Korean Journal of Environmental Biology
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    • v.39 no.4
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    • pp.536-541
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    • 2021
  • Pantala flavescens is a dominant Odonata species in the rice fields in Korea. To determine the effects of different temperatures on its larval growth and emergence, field and laboratory experiments were conducted. Larval growth was also monitored in mono-cropping and double-cropping rice fields. The growth of larvae was monitored every week by measuring the head width. In the field experiment, no difference was found in larval growth and emergence between the control temperature and +1.9℃ of the control temperature. The larval growth was greater at 23℃ than at 20℃ laboratory temperatures, and no emergence was recorded at either temperature after eight weeks of monitoring. There was a quadratic relationship between larval growth and temperature in an incubator at five temperature regimes of 15, 20, 25, 30, and 35℃. Midseason water drainage caused the extinction of the existing individuals and newly hatched larvae dominated after re-watering in the rice fields. Larval size was greater in double-cropping fields than in mono-cropping fields in late July but the tendency was reversed in early August. The results of this study suggest that temperature warming will directly promote the larval growth of P. flavescens and indirectly influence seasonal growth via changes in water management in rice fields.