• 제목/요약/키워드: Growth & development

검색결과 12,681건 처리시간 0.043초

NELL2 Function in Axon Development of Hippocampal Neurons

  • Kim, Han Rae;Kim, Dong Hee;An, Ji Young;Kang, Dasol;Park, Jeong Woo;Hwang, Eun Mi;Seo, Eun Jin;Jang, Il Ho;Ha, Chang Man;Lee, Byung Ju
    • Molecules and Cells
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    • 제43권6호
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    • pp.581-589
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    • 2020
  • Neurons have multiple dendrites and single axon. This neuronal polarity is gradually established during early processes of neuronal differentiation: generation of multiple neurites (stages 1-2); differentiation (stage 3) and maturation (stages 4-5) of an axon and dendrites. In this study, we demonstrated that the neuron-specific n-glycosylated protein NELL2 is important for neuronal polarization and axon growth using cultured rat embryonic hippocampal neurons. Endogenous NELL2 expression was gradually increased in parallel with the progression of developmental stages of hippocampal neurons, and overexpression of NELL2 stimulated neuronal polarization and axon growth. In line with these results, knockdown of NELL2 expression resulted in deterioration of neuronal development, including inhibition of neuronal development progression, decreased axon growth and increased axon branching. Inhibitor against extracellular signal-regulated kinase (ERK) dramatically inhibited NELL2-induced progression of neuronal development and axon growth. These results suggest that NELL2 is an important regulator for the morphological development for neuronal polarization and axon growth.

동중국해에 분포하는 갈치(Trichiurus lepturus)의 연령과 성장 (Age and Growth of Largehead Hairtail Trichiurus lepturus in the East China Sea)

  • 김영혜;유준택;이은희;오택윤;이동우
    • 한국수산과학회지
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    • 제44권6호
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    • pp.695-700
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    • 2011
  • Age, growth, and maturity of Trichiurus lepturus were estimated based on right-handed sagittal otoliths belonging to 1,031 fish collected from January to December 2007 in the East China Sea. The outer margins of the otolith were examined and showed that an opaque zone was formed once per year. Marginal increments in otoliths formed as annual rings between June and August, at the beginning of the spawning season. Fish growth was expressed by the von Bertalanffy growth equation, as follows: $L_t=494.0$ ($1-e^{-0.2453(t+-0.4822)}$) for females and $L_t=330.4$ ($1-e^{-0.4292(t+0.7513)}$) for males, where $L_t$ is the total length in mm and t is age in years. The growth rates of males and females were significantly different (P<0.05).The age composition ranged mostly between ages 2 and 4, and the oldest individuals were 4 years old in males and 6 years old in females. Finally, the age composition of largehead hairtail was compared with data from the 1970s and is discussed in the context of environmental changes.

The Impact of Financial Integration on Economic Growth in Southeast Asia

  • Bong, Angkeara;Premaratne, Gamini
    • The Journal of Asian Finance, Economics and Business
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    • 제6권1호
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    • pp.107-119
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    • 2019
  • This paper examines the impact of financial integration on economic growth in Southeast Asia over the period 1993-2013. This paper further investigates whether the relationship depends on the level of financial and economic development, government corruption, and macroeconomic policy. These questions raise important issues both from a theoretical and a policy perspective. We employ the generalized methods of moment (GMM) in the dynamic panel estimation framework to analyse several factors, including initial income, initial schooling, financial development, inflation, trade openness, corruption, and financial crisis. The study further analyzes the data using the EGLS model to examine the consistency of the GMM model. We found that financial integration has a significant positive effect on economic growth in Southeast Asia. Our findings suggest that increasing financial integration could improve the productive capacity of the economy, including more investments and efficient allocation of capital, and thus enhancing economic growth in this region. More specifically, the results suggest that the government should work towards eliminating corruption and stabilizing macroeconomics in order to enhance financial integration and economic growth. This paper sheds new insights on a better evaluation of the past and present theorizing on the subject of financial integration and economic growth; especially, in Southeast Asia.

Effect of Waterlogging Duration on Growth Characteristics and Productivity of Forage Corn at Different Growth Stages Under Paddy Field Conditions

  • Jung, Jeong Sung;Choi, Gi-Jun;Choi, Bo-Ram
    • 한국초지조사료학회지
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    • 제39권3호
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    • pp.141-147
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    • 2019
  • The purpose of this study was to determine the effect of waterlogging duration on the growth characteristics and productivity of forage corn at different growth stages under paddy field conditions. Treatments consisted of waterlogging at two growth stages (V7 or V14) for four waterlogging durations (no waterlogging, 48 hours, 72 hours, and 96 hours, respectively). The V14 growth stage was more vulnerable to waterlogging than the V7 stage. Among the waterlogging durations, the lodging score increased at 48 hours. The stem height of forage corn decreased with the increase in waterlogging duration at the different growth stages (V7 and V14). Increase in waterlogging duration reduced the stem dry matter yield, ear dry matter yield, and total dry matter yield at both growing stages (V7 and V14). The waterlogging treatments at the V14 stage affected ear dry matter yield more than those at the V7 growing stage. Thus, the management of forage corn under paddy field conditions must be strengthened during early (V7) and grain fill stages (V14). When waterlogging occurs, surface and subsurface drainage should be implemented within 48 hours to control (no waterlogging) the groundwater level and, thus, minimize economic losses due to forage corn damage.

Effect of Agricultural Exports and Imports on Economic Growth in Bangladesh: A Study on Agribusiness Supply Chain

  • HASAN, Mostofa Mahmud;HOSSAIN, BM Sajjad;SAYEM, Md. Abu;AFSAR, Mahnaz
    • 유통과학연구
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    • 제20권11호
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    • pp.79-88
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    • 2022
  • Purpose: The purpose of this study was to determine the effect of agricultural exports and imports on economic growth in Bangladesh and propose an upgraded and customized model of the supply chain for agribusiness growth in Bangladesh to achieve plain sailing and systematic operation and financial gains at home and abroad. Research design, data, and methodology: All data in the research have been collected from secondary sources. Gross domestic product was used as the dependent variable and exports and imports of agricultural products were used as independent variables. Pairwise Granger causality was utilized to see the impact of the variable responsible for the economic growth in Bangladesh and the causal relationship between the variables analyzed was measured using Johansen co-integration test. Results: From the empirical analysis, the researchers observed that agricultural commodity imports and exports have a unidirectional impact on economic growth in Bangladesh and a long-run causal link with economic growth in Bangladesh. The suggested supply chain model of agribusiness aids in achieving smooth operations, systematic management, and monetary gains both domestically and internationally. Conclusions: This paper contributes to the development of a more effective and profitable agribusiness supply chain in Bangladesh systematically through their theoretical and practical implications.

Domestic Government Debt and Economic Growth in Indonesia: An empirical analysis

  • Bukit, Alexander Romarino;Anggraeni, Lukytawati
    • 융합경영연구
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    • 제5권1호
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    • pp.27-37
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    • 2017
  • Domestic government debt securities is one of the steps which is taken by the government of Indonesia as a major source of financial budget, covering for the budget deficit, debt payments and interest debt. The purposes of this research are to know the development of budget deficits, government debt and impact of domestic government debt securities against economic growth in Indonesia. Method of analysis used Ordinary Least Squares (OLS) analyzing the impact of the domestic debt against economic growth in Indonesia. This research uses time series data from 1997 to 2014. Total government debt and domestic government debt securities in Indonesia increased during the last five years. The average of domestic government securities was above 50 percent of the total government debt. Estimated results showed domestic government debt securities has a positive and significant effect to economic growth. Official development assistance (ODA) has a negative effect to economic growth. Other variables such as the gross fixed capital formation and receipt of remittance have positive and significant effect, total imports and government expenditure have negative and significant effect against economic growth.

Effect of Maternal Undernutrition during Late Pregnancy on Growth and Development of Ovine Fetal Visceral Organs

  • Gao, F.;Liu, Y.C.;Hou, X.Z.
    • Asian-Australasian Journal of Animal Sciences
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    • 제22권12호
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    • pp.1633-1639
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    • 2009
  • This study investigated the effect of maternal undernutrition during late pregnancy on the growth and development of ovine fetal visceral organs. One hundred Mongolian ewes were mated at a synchronized oestrus and divided into three groups and offered 0.175 MJ ME $kgw^{-0.75}\;d^{-1}$ (Restricted Group1; RG1), 0.33 MJ ME $kgw^{-0.75}\;d^{-1}$ (Restricted Group2; RG2) and ad libitum access to feed (Control Group; CG) during late pregnancy (90 days). Selected animals in each group were slaughtered immediately at d 90 of pregnancy and after parturition (neonatal lambs), and major visceral organs were removed and weighed separately. The results indicated that the weights of lung (p<0.01), spleen (p<0.01), heart (p<0.05), liver (p<0.05) and abomasum (p<0.01) in RG1 were significantly lighter than those of CG. For RG2, only the weights of the lung (p<0.05) and spleen (p<0.01) were significantly lighter than those of CG; when expressed as a percentage of body weight, significance was retained in the spleen (p<0.01) for both restricted groups, but the percentage of brain in RG1 was significantly higher than that in CG (p<0.01). For lung and spleen, the amount of DNA was significantly lower (p<0.01) in both groups of restricted neonatal lambs compared to CG; however, there was a significant difference only between RG1 and CG for protein: DNA ratio (p<0.01). The DNA content of kidney, abomasum and jejunum were decreased (p<0.05) in RG1 neonatal lambs, but protein: DNA ratio in the liver was decreased compared with that of CG (p<0.05). The plane of maternal undernutrition during late pregnancy had a significant effect on the growth and development of fetal visceral organs, which altered ontogeny of fetal organ growth and development. These perturbations in fetal visceral development may have significant implications on postnatal growth and adult health.

감각자극 프로그램이 영아의 성장과 행동발달에 미치는 효과 (Effects of A Sensory Stimulation Program on Growth and Behavioral Development of Infants)

  • 김정선
    • 대한간호학회지
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    • 제29권6호
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    • pp.1445-1454
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    • 1999
  • This study was designed to investigate the effects of a sensory stimulation program on the growth (weight, height, head circumference, and chest circumference), behavioral development, behavioral states, and the heart rate of the infants. A total of 23 infants of 2 weeks old were divided into sensory stimualtion group (11 infants) and control group (12 infants). The infants of sensory stimulation group had received sensory stimulation for 6 weeks. Sensory stimulation program was composed of tactile and kinesthetic stimulation. We assessed growth, behavioral state and heart rate every week and behavioral development every 2 weeks. The results were as follows: 1. Body weight in sensory stimulation group, from two weeks after the sensory stimulation program, was significantly increased more than control group, but there was no significant difference in height, head circumference, and chest circumference between the two groups. 2. Behavioral developmental score of sensory stimulation group was significantly higher than that of control group from two weeks after the sensory stimulation program. Developmental states of sensory stimulation group showed more 'high average developmental state' than the control group from 4 weeks after sensory stimulation program. 3. Behavioral states of sensory stimulation group after the sensory stimulation program, the 'sleeping state' was significantly increased more than control group. The 'awakening state' and the state of fuss or crying were significantly less than those of the control group. 4. The heart rate of the sensory stimulation group after the sensory stimulation was significantly lower than the control group. These results indicate that the sensory stimulation program decreases heart rate and improves the sleeping state to be effective on promoting the growth and development of the infants. In view of these experiments, we suggest sensory stimulation program might be considered as a nursing intervention for growth and development of the infants not only in clinical settings but also at homes and in the communities.

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액상 대두 유아식을 3개월 이상 섭취한 영유아의 성장과 발달 (Growth and Development of Infants Fed Soy- Based Formulas over 3 Months)

  • 조상운;신해철;손헌수;정재원;남희정;박혜련
    • 대한지역사회영양학회지
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    • 제9권5호
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    • pp.555-565
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    • 2004
  • The objective of this study was conducted to investigate growth and development status of infants fed soy-based formulas over 3 months. The height and weight were measured and Z-scores were calculated by using standard of the same age groups. Their mothers were interviewed using questionnaires including general and environmental characteristics, total food intakes, soy based formula intakes and Ewha infant development screening test. Main results were as follows: 1) Nutrient intake levels of subjects were similar to or more than the level of Korean Recommended Dietary Allowances except for intakes of vitamin E (79.89% RDA), and the average status of nutrient intakes of infants were fairly good. 2) Z-scores of height for age (HAZ) and Z-scores of weight for age (WAZ), Kaup index, WLI and Ewha Infant Developmental Screening Test score of subjects were in the normal growth range. 3) There were no significant differences among soy based formula intake percentile groups in HAZ, WAZ, Kaup index, WLI and Ewha Infant Developmental Screening Test score. 4) Total energy intake was positively correlated with HAZ (p < 0.00, WAZ (p <0.00, and WLI (p < 0.05) in infants less than 12 month. Also, soy based formula energy intake was positively correlated with HAZ (p < 0.05) in infants less than 12 month. However, energy and soy based formula intake levels of infants over 12 month were not significant among variables. Considering results of this study, infants fed soy-based formulas over 3 months showed normal growth and development status. Further studies are needed to evaluate longterm growth and development in infants fed soy based formulas.

1990년대 중국 사영기업의 성장과 지역발전 (The Growth of Private Enterprises in the 1990s and Regional Development in China)

  • 이원호
    • 한국경제지리학회지
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    • 제8권2호
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    • pp.285-299
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    • 2005
  • 1978년 말 시작된 중국의 경제개혁은 시간이 지남에 따라 그 속도와 깊이가 심화되고 있으며, 특히 최근에 진행되고 있는 사영기업의 성장이 갖는 의미는 경제적으로나 정치적으로 매우 중요하지만, 공간적으로도 그 발전의 차별성으로 인해 특정지역의 발전과 지역불균등 성장패턴에 미치는 영향이 심대하다. 본 연구는 사영기업의 발전경로를 규정해 온 제도적 변화와 함께 사영기업 성장의 지역구조를 이해하고자하였다. 사영기업의 성장 이면에는 경제개혁의 근본접근양식이 시장화전략과 경제개혁이 진행됨에 따라 나타나는 실업의 문제해결이라는 중요한 동기가 자리 잡고 있다. 사영기업 발전의 지역패턴 또한 지속적으로 심화되는 공간적 차별화에 의해 특징 지워진다. 지역통계자료에 기초한 일차적인 분석결과, 사영기업의 발전은 지역경제의 시장화정도와 밀접한 관련성을 보이게 된다. 따라서 향후 경제발전의 지역적 패턴특정은 경제 개혁의 진전과 시장화 수준에 따라 결정될 것으로 생각되며, 이는 향후 지역발전을 위한 전략 수립에서 사영기업 발전전략이 차지하는 중요성을 뚜렷히 보여준다.

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