• Title/Summary/Keyword: Groups Identification

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Identification of Potential Prognostic Biomarkers in lung cancer patients based on Pattern Identification of Traditional Korean Medicine Running title: A biomarker based on the Korean pattern identification for lung cancer

  • Ji Hye Kim;Hyun Sub Cheong;Chunhoo Cheon;Sooyeon Kang;Hyun Koo Kim;Hyoung Doo Shin;Seong-Gyu Ko
    • Journal of Society of Preventive Korean Medicine
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    • v.27 no.2
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    • pp.35-48
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    • 2023
  • Objective : We studied prognostic biomarkers discovery for lung cancer based on the pattern identification for the personalized Korean medicine. Methods : Using 30 tissue samples, we performed a whole exome sequencing to examine the genetic differences among three groups. Results : The exome sequencing identified among 23,490 SNPs germline variants, 12 variants showed significant frequency differences between Xu and Stasis groups (P<0.0005). As similar, 18 and 10 variants were identified in analysis for Xu vs. Gentleness group and Stasis vs. Gentleness group, respectively (P<0.001). Our exome sequencing also found 8,792 lung cancer specific variants and among the groups identified 6, 34, and 12 variants which showed significant allele frequency differences in the comparison groups; Xu vs. Stasis, Xu vs. Gentleness group, and Stasis vs. Gentleness group. As a result of PCA analysis, in germline data set, Xu group was divided from other groups. Analysis using somatic variants also showed similar result. And in gene ontology analysis using pattern identification variants, we found genes like as FUT3, MYCBPAP, and ST5 were related to tumorigenicity, and tumor metastasis in comparison between Xu and Stasis. Other significant SNPs for two were responsible for eye morphogenesis and olfactory receptor activity. Classification of somatic pattern identification variants showed close relationship in multicellular organism reproduction, anion-anion antiporter activity, and GTPase regulator activity. Conclusions : Taken together, our study identified 40 variants in 29 genes in association with germline difference of pattern identification groups and 52 variants in 47 genes in somatic cancer tissues.

Study on the Benefit of Medical Herbal Cosmetics via the pattern identification about fluid-humor of skin in Traditional Korean Medicine (한방 피부 진액변증을 통한 한방화장품의 효능 평가)

  • Kim, Kyoung-Shin;Kim, Byoung-Soo
    • Journal of Haehwa Medicine
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    • v.21 no.1
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    • pp.1-9
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    • 2012
  • Objectives : The aim of this experiment is to find out relationship between the effect of cosmetics and 4 types of pattern identification about fluid-humor, which are based on the general idea of traditional oriental medicine, Qi-Blood and deficiency-excess. Methods : Korean female volunteers in good health (n=25, $23.12{\pm}2.83$) participated in this experiment. Three Korean medical doctors classified them into 4 groups: Blood-deficiency: group A; Blood-excess: group B; Qi-deficiency:group C; Qi-excess:group D). Cosmetics that contains herb extract for Blood deficiency were given to all volunteers and they used the cosmetics for 4 weeks. Volunteers were assessed non-invasively with the skin measuring devices before and after using cosmetics. And we analyzed the correlation of skin physiological parameters with 4 groups. Results : Three doctors diagnosed participants and classified them into 4 groups ; group A(n=8),group B(n=7), group C(n=3), group D(n=5) as highest score. After 4 weeks, facial skin moisture showed no significant difference in comparison between 4 groups. Sebum showed significant increase in Group A and significantly decreased Group B. Measurement of facial skin elasticity tended to increase in Group A, C, D but skin elasticity was decreased significantly in Group B. Conclusions : In case of a group that pattern identification about fluid-humor corresponds to herb extract in cosmetic, skin improving effect was better than the other group that pattern identification oppose to properties of herb in cosmetic. Therefore, from the view of traditional oriental medicine, it is very important to understand user's pattern of identification or physical conditions and properties of herbs in cosmetics on the matter of safety and efficacy.

Research on Pattern Identification and Clinical Characteristics of Female Patients with Cold Hypersensitivity of Hands and Feet (수족냉증을 호소하는 여성 환자의 임상 특성 및 한방 변증에 관한 연구)

  • Kwon, Na-Yoen;Yoo, Joon-Sang;Go, Ho-Yeon;Kim, Hyeong-Jun;Lee, Dong-Nyeong
    • The Journal of Korean Medicine
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    • v.41 no.2
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    • pp.96-106
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    • 2020
  • Objectives: The purpose of this study was to research the demographical and gynecologic characteristics, quality of life, and analyze the pattern identification in female patients with cold hypersensitivity of hands and feet. Methods: 112 participants were recruited from May 2018 to April 2019 from three korean medical hospitals. The data was composed of general characteristics, degree of coldness of hands and feet, gynecological questionnaire, score of WHOQOL-BREF and pattern identification. We divided data into 2 groups: The group of patients who meet the criteria for diagnosis of coldness on feet and the group of patients who meet the criteria for diagnosis of coldness on feet and hands. We tried to compare data by groups using Excel 2016 for windows and SPSS for windows (Ver. 23.0). Results: Throughout the study, we found differences between 2 groups in weight, body mass index (BMI), VAS score of cold hypersensitivity on feet, temperature of PC8, ST32, and pattern identification. Conclusions: After the study, we confirmed that even though both groups suffer from cold hypersensitivity of hands and feet, they show clinical differences in each group and differences in pattern identification.

STUDIES ON BLOOD GROUP SPECIFIC SUBSTANCE IN THE DENTAL HARD TISSUE -IDENTIFICATION OF A. B. O. BLOOD GROUPS FROM DENTAL HARD TISSUE LEFT STANDING UNDER VARIOUS CONDITIONS- (치아편조직의 혈형물질 검출에 관한 실험적 연구 -제매장조건하의 치아경조직에서 혈액형판정-)

  • Kim, Chong-Youl
    • The Journal of the Korean dental association
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    • v.19 no.5 s.144
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    • pp.449-461
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    • 1981
  • The author studied on the blood groups by the elution tests with teeth left standing under various conditions, and the following results were obtained. 1) The blood group identification with dental hard tissue proved to be possible. 2) In the cases of teeth left under various conditions-formalin fixation, standing in air, soil embedding and immersing in water-the identification of blood groups was possible in every case without any difference on difficulties. 3) The reaction of agglutination was somewhat more obvious in dentin substance than in enamel. 4) About 10 mg of dental hard tissue was recommendable for blood grouping.

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Unification of neural network with a hierarchical pattern recognition

  • Park, Chang-Mock;Wang, Gi-Nam
    • Proceedings of the ESK Conference
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    • 1996.10a
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    • pp.197-205
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    • 1996
  • Unification of neural network with a hierarchical pattern recognition is presented for recognizing large set of objects. A two-step identification procedure is developed for pattern recognition: coarse and fine identification. The coarse identification is designed for finding a class of object while the fine identification procedure is to identify a specific object. During the training phase a course neural network is trained for clustering larger set of reference objects into a number of groups. For training a fine neural network, expert neural network is also trained to identify a specific object within a group. The presented idea can be interpreted as two step identification. Experimental results are given to verify the proposed methodology.

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Power System State Estimation and Identification in Consideration of Line Switching (선로개폐상태를 포함하는 전력통계 상태추정및 동정)

  • 박영문;유석한
    • 전기의세계
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    • v.28 no.3
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    • pp.57-64
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    • 1979
  • The static state estimation are divided into two groups; estimation and detection & identification. This paper centers on detection and identification algorithm. Especially, the identification of line errors is focused on and is performed by the extended W.L.S. algorithm with line swithching states. Here, line switching states mean the discrete values of line admittance which are influenced by unexpected line switching. The numerical results are obtained from the assumption that the noise vector is independent zero mean Gaussian random variables.

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The correlation between average temperature & precipitation and Pattern Identification of the patients with stroke (중풍환자의 변증(辨證)과 기온 및 강수여부와의 상관성에 관한 연구)

  • Ma, Mi-Jin;Kim, Bo-Ram;Kim, Mi-Kyung;Choi, Dong-Jun;Han, Chang-Ho;Jung, Seung-Hyun;Shin, Gil-Jo;Lee, Won-Chul
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.9 no.1
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    • pp.8-13
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    • 2008
  • Objectives : This study was to investigated the correlation between average temperature & precipitation and pattern identification of the patients with stroke. Methods : 115 stroke patients within 30days of onset were registered during the study period. Pattern identification of stroke was classified into Fire and heat, Turbid phlegm and others. We took the mean of average temperature according to pattern identification and analyzed pattern identification into two groups according to climatological normal of average temperature in Seoul. We also analyzed pattern identification into two groups according to existence of precipitation. Results : Heat and fire, and other type of pattern identification had high frequency when average temperature was higher than 12.2℃. And there was no correlation between precipitation and pattern identification of stroke.

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The Study on Internal Service Quality, Service Quality to Patients, Job Satisfaction, Organizational Identification and Job Identification of Physical Therapists (물리치료사의 내부서비스품질, 외부 서비스품질, 직무만족, 조직동일시 및 직업동일시에 관한 탐색적 연구)

  • Jung, Taek-Cheol
    • Journal of the Korean Society of Physical Medicine
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    • v.5 no.3
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    • pp.421-434
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    • 2010
  • Purpose : The purpose of this study is to understand the attitudes to internal service quality between coworkers, service quality to patients, job satisfaction, organizational identification and job identification of physical therapists in medical organizations. Methods : Data were collected from physical therapists working in medical organizations. 195 questionnaires were analyzed. Participants' total mean, group mean by age, sex, career and type of medical organization and the variables' correlations were examined. Results : The attitudes of physical therapists to five variables were very positive. Especially job identification was strong. The significant differences between groups were found in some variables. All variables except age and career were positively related to each other. The correlation between age and career was very high. Age and career were related to some of variables. Conclusion : To improve organizational performances it should be a top priority to understand the attitudes of physical therapists in organizations.

Effectiveness of Enneagram Group Counseling for Self-identification and Depression in Nursing College Students (에니어그램 집단상담이 간호대학생의 자아정체감과 우울에 미치는 효과)

  • Lee, Jeong Seop;Yoon, Jeong Ah;Do, Keong Jin
    • Journal of Korean Academy of Nursing
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    • v.43 no.5
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    • pp.649-657
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    • 2013
  • Purpose: The purpose of this study was to examine effects of enneagram group counseling program on self-identification and depression in nursing college students. Three groups, categorized by how the students solve their conflicts, were selected to identify changes from the program. Methods: A quasi-experimental study with a non-equivalent control group and pre posttest design was used. Participants were assigned to the experimental group (n=30) or control group (n=33). The experimental group participated in enneagram group counseling program for 38 hours through eight sessions covering four different topics. Collected data were analyzed using Chi-square test, Fisher's exact test, t-test, and Wilcoxon signed rank test. Results: Total self-identity score for the experimental group was significantly higher than the control group. However, there was no significant difference between the two groups for depression scores. The Assertive and Compliant groups demonstrated significant change in self-identification while the Withdrawn groups did not reveal any change. Conclusion: Results indicate that the enneagram group counseling program is very effective in establishing positive self-identification for nursing college students who face developmental crisis and stressful situations. It is also expected that this program would be useful to enhance the students' confidence through a deeper understanding and acceptance of themselves.

A Study on the Characteristics of Pulse Waves according to Eight Principle Pattern Identification in 500 Women (500명 여성을 대상으로 한 팔강변증에 따른 맥파 특성 연구)

  • Lee, In Seon;Jeon, Soo Hyung;Kang, Chang Wan;Kim, Jong Won
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.35 no.6
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    • pp.274-279
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    • 2021
  • This study was conducted to find objective diagnostic indicators for the Eight Principle Pattern Identification using a pulse wave analyzer. Typology Complexion Pulse and Symptom data from 500 women over the age of 18 were used. Five experts made a diagnosis of Eight Principle Pattern Identification and divided the subjects into 'Yin-Yang', 'Exterior-Interior', 'Cold-Heat', 'Deficiency-Excess' groups. Their pulse waves were measured in the left and right radial arteries, and it was investigated whether there was a significant difference between groups in the pulse wave parameter values. 'Yin' group showed a significantly lower value in the left radial artery for Ener, Emin, EIX, T4T, T4TT parameters and in the Right for T2, T2T, T5. The Vmag, As and Ad parameters were significantly different between the 'Exterior' and 'Interior' groups. 'Heat' group showed a significantly higher value in the right radial artery for RAI/t parameter. 'Deficiency' group showed a significantly higher value in the right radial artery for W, Angl parameters. Through this study, significant pulse wave parameters were found, and they can be used as objective diagnostic indicators for Eight Principle Pattern Identification.