• 제목/요약/키워드: Group effect

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개인 트레이를 이용한 불소도포 효과에 관한 실험적 연구 (The study of the fluoridation effect via individual tray compared with other methods)

  • 조병근;서은주
    • 한국치위생학회지
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    • 제1권2호
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    • pp.251-260
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    • 2001
  • The purpose of this article was to compare the fluoridation effect via individual tray with other professional methods. In oder to compare the fluoridation effect, 40 extracted human teeth was divided into 4 groups(each group was composed of 10 teeth) and the surface hardness of each group was tested in untreated, after fluoridation, after fluoridation and etching by 10% lactic acids. group I: no fluoridation(control) group II : fluoridation with 123%APF group III : fluoridation by iontophoresis with 2% NaF group IV : fluoridation by individual tray with 4% SnF2 gel Surface hardness was measured with Micro hardness tester(Shimadzu Co. Japan), Data analysis was conducted using the repeated measures ANOVA test. The results were as follows: 1. Four tested groups demonstrated nearly the same SMH in extracted state. 2. The SMH after fluoridation showed $330.57{\pm}139.09kg/mm^2$ in group IV, $221.79{\pm}187.48kg/mm^2$ in group II, $186.43{\pm}53.13kg/mm^2$ in group III. So the SMH of group IV, II were was significantly increased(p<0.01). 3. The SMH of group II, III, IV after acid etching was higher than the control group(p<0.01). 4. The SMH between group II, III, and IV after acid etching was not different significantly.

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흰쥐의 중대뇌동맥 결찰로 유발된 뇌허혈에서 성향정기산과 곽향정기산이 신경세포에 미치는 효과 (The Effects of Sunghyangjunggi-san and Gwackhyangjunggi-san Extracts on Cerebral Ischemia Following the MCA Occlusion in Rat)

  • 김선영;이원철
    • 대한한의학회지
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    • 제22권4호
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    • pp.142-150
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    • 2001
  • Objectives : The purpose of this investigation is to evaluate and compare the effects of Sunghyangjunggi-san (SH) and Gwackhyangjunggi-san (GH) extracts on reperfusion following the MCA occlusion in rats. Methods : To evaluate the effect of Sunghyangjunggi-san (SH) and Gwackhyangjunggi-san (GH) extracts on reperfusion following the MCA occlusion, the volume of cerebral infarction and edema were measured and the change of the CA1 pyramidal neurons in the hippocampus were investigated by light microscopy. Results : 1. The infarction volume of the control group was 23.6%, that of the GH group was 23.7%, and that of the SH group was 18.5%. 2. The brain edema volume of the control group increased by 16% compared with that of the normal group, that of the GH group increased by 14%, and that of the SH group increased by 9%. 3. The number of surviving pyramidal neurons in the CAI area of the hippocampus was investigated under light microscopy. In the control group, few surviving pyramidal neurons excisted (mean 6.4) and similarly in the GH group (mean 8.5), but in the SH group, the number of surviving pyramidal neurons was significantly higher, to the mean 18.4. Conclusions : According to the above results, in regard to the damage of neurons following cerebral ischemia, the GH group has little effect of the protection of neurons compared to the control group, but the SH group has a remarkable effect.

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한국에서 상용되는 식용유지로 사육된 흰쥐의 체내 지방대사 및 면역능력에 대한 연구 (The Effect of Sesame Oil, Perilla Oil and Beef Tallow on Body Lipid Metabolism and Immune Response)

  • 김우경
    • Journal of Nutrition and Health
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    • 제22권1호
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    • pp.42-53
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    • 1989
  • The research was designed to study the effect of different fat sources and levels on Body lipid metabolizm and immune responses in Sprague-Dawely strain male rats. These effect of different fat sources compared with sesame Oil, Perilla oil and Beet tallow. Fat sources were divided into 3 groups respectively 7%, 15%, 30% fat level on diet weight basis. The experimental period was 54days. 1) The body weight gain was significantly low in NF group. In Sesame oil group and perilla oil group, low fat level groups were higher than medium, high fat level groups. But in Beef tallow group, high fat level groups were higher than low and Medium groups. 2) The weight of liver, kidney and epididymal fat ped tend to increse with increasing body weight. 3) The contents of triglyceride and total lipid in serum were significantly different with dietary fat sources and Perilla oil group was the lowest. 4) The contents of triglyceride and total lipid in liver were significantly different with dietary fat levels and high fat level group was higher than low fat level group. 5) Perilla oil group, compared with Beef tallow group, showed the higher excretion of cholesterol through feces and the higher deposit of cholesterol in liver. Therefore serum cholesterol level of Perilla oil group was lower than that of Beef tallow group. But eventhough Sesame oil is vegetable oil, Sesame oil did not showed an effect like Perllia oil on serum cholesterol level. 6) Weight of thymus decreased with fat levels particularly in vegetale oil. And it had on effect on mitogen response, mitogen response decreased with fat level in vegetable oil. But in Beef tallow, there was no difference in fat level.

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귀비탕(歸脾湯), 가미온담탕(加味溫膽湯) 및 귀비온담탕(歸脾溫膽湯)의 항(抗) Stress 효능(效能) 비교연구(比較硏究) (A study of the comparative effect of Kuibitang, Kamiondarmtang, and Kuibiondarmtang on serum levels in rats under the immobilization stress.)

  • 김형철;정대규
    • 동의신경정신과학회지
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    • 제4권1호
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    • pp.99-119
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    • 1993
  • In order to compare and examine the effect the effect of Kuibitang, Kamiondarmtang and Kuibiondarmtang against stress, I induced immobilization stress by binding rats for 200mins under a little anesthetized with ether. I classified as normal group, control group which administrated 0.9% NaCl solution, sample A group which administrated Kuibitang, sample B group which administrated Kamiondarmtang and sample C group which administrated Kuibiondarmtang. I got some conclusions by measuring amounts of norepinephrine, epinephrine, triiodothyronine($T_3$) and thyroxine($T_4$) in 1, 3 and 5 days, respectively. 1. Norepinephrine showed high meaningful decrease after 1. 3 and 5 days in sample A group. It showed little decrease in sample B group. It showed a little meaningful decrease after 1 day and high meaningful decrease after 3 and 5 days in sample C group. 2. Epinephrine showed high meaningful decrease after 3 and 5 days in sample A group. It showed little decrease in sample B group. It showed a little meaningful decrease after 3 days and high meaningful decrese after 5 days in sample C group. 3. Triiodothyronine($T_3$) inclined to approach normal value in sample A, B, C group in comparision wit control group but didn't have high meaning. 4. Thyroxine($T_4$) inclined to approach normal va1ue in sample A, B, C group in comparision with contrl group but didn't have high meaning. As I consider the effect of experiments, I think that Kuibitang and Kuibiondarmtang have some effects against stress and it is right to apply to the treatment of stress.

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Yoga와 Pilates 운동 수행이 자율신경계에 미치는 영향 (The Effect of the Exercise Performance of Yoga and Pilates on the Autonomic Nervous System)

  • 김지선
    • 한국산학기술학회논문지
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    • 제16권7호
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    • pp.4450-4458
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    • 2015
  • 본 연구의 목적은 Yoga와 Pilates 운동 수행이 자율신경계에 미치는 영향을 분석하여 운동처방의 임상적 기초 자료를 제공하고자 하였다. 피험자는 체육전공 대학생 20명을 요가운동군(Yoga Group)과 필라테스운동군(Pilates Group)에 각각 10명씩 배정하였고, 자율신경계 측정은 운동 전, 운동 직후, 회복기 30분 후에 이루어졌다. 그 결과 첫째, 요가는 스트레스 지수와 평균맥박이 시기의 주효과와 시기와 집단의 상호작용효과의 유의한 차이를 보였다. 둘째, 요가는 교감활성과 자율신경균형이 시기의 주효과, 시기와 집단의 상호작용효과, 집단의 주효과 모두 유의한 차이를 보였다. 셋째, 맥박다양성, 부교감활성도, SDNN, RMSSD는 시기의 주효과는 유의한 차이를 보였고, 시기와 집단의 상호작용효과와 집단의 주효과는 통계적으로 유의한 차이를 나타내지 않았다. 따라서 요가는 스트레스 지수를 낮추고 평균맥박 감소의 효과를 얻을 수 있으며, 특히 요가 운동이 필라테스 운동보다 교감활성 감소와 자율신경균형에 더 긍정적인 영향을 미치는 것으로 사료된다.

加味柱枝湯이 알레르기 비염에 미치는 영향에 관한 실험적 연구 (The Experimental Stydy on the Anti-Allergic Rhinitis Effects of the Gamigyeji-tang)

  • 심성용;김경준
    • 한방안이비인후피부과학회지
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    • 제17권1호
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    • pp.45-54
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    • 2004
  • Major symptoms of allergic rhinitis are nasal obstructions, sneezing and watery rhinorrhea. Gamigyeji-tang has been used to treat for watery rhinorrhea, which is one of the symptoms of allergic rhinitis. This experimental study was done to rescarch effects of Gamigyeji-tang. We have studied effect of mice on OVA-induced Production of IL-4, IL-5, IFN-${\gamma}$ by Murine Splenocytes, and effect of OVA-induced total IgE and OVA-Specific IgE. The results were as follows ; 1. In IL-4 study, Gamigyeji-tang treated group was proved significant inhibitory effect(p〈0.005) 2. In IL-5 study, Gamigyeji-tang treated group was proved significant inhibitory effect.(p〈0.05) 3. In IFN-${\gamma}$ study, Gamigyeji-tang treated group was proved significant inhibitory effect(p〈0.000001) 4. In Total IgE, Gamigyeji-tang treated group didn't showed significant inhibitory effect. 5. In OVA-specific IgE, Gamigyeji-tang treated group didn't showed significant inhibitory effect. According to this result, Gamigyejj-tang was concluded to be effective on anti-allergic action. More studies are required to investigate the mechanism of inhibition by herbal medicine in allergic rhinitis model.

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침자(鍼刺) 및 봉독요법(蜂毒療法)이 Carrageenin으로 유발(誘發)된 흰쥐의 슬관절(膝關節) 염증성(炎症性) 부종(浮腫)에 미치는 효능(效能)에 대(對)한 비교(比較) 연구(硏究) (Comparative effects of Apitoxin(Bee Venom) & Regular Acupuncture therapy on the knee joint arthritis induced by carrageenin solution in rats)

  • 김갑성
    • 대한한의학회지
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    • 제16권1호통권29호
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    • pp.379-402
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    • 1995
  • This study was performed to investigate the comparative effects of Apitoxin(0.1% bee venom 0.1cc) & Acupuncture therapy on the knee joint arthritis induced by 0.1% carrageenin solution at Rt. knee joint in rats. After carrageenin injection, the apitoxin was injected for two times (Experimental group I : 1 & 24hours later, Experimental group II : 48 & 72hours later) into the corresponding loci to Rt. $ST_{35}$(Group 3) & $EX-LE_4$(group 4) of the human body in rats. Acupuncture therapy was done same as above. And then the comparative effects of apitoxin and acupuncture therapy on the knee joint arthritis were estimated by the WBC count, RBC count, hemoglobin level, hematocrit level and ASO titer in serum. The results were summerized as follows : 1. The effects of apitoxin & acupuncture on WBC count showed remarkable decrease at group 3 & group 4 as compared with the control group in both experimental group I & experimental group II. There were not any statistical difference from apitoxin and acupuncture therapy by Duncan's multiple range test. 2. The effect of apitoxin on RBC count showed noticeable decrease at group 3 & group 4 as compared with the control group in both experimental group I & experimental group II. The acupuncture was not showed decrease at group 3 & group 4 as compared with the control group in both experimental group I & experimental group II. There were not any statistical difference from apitoxin and acupuncture therapy by Duncan's multiple range test. 3. The effects of apitoxin & acupuncture on hemoglobin level showed noticeable decrease at group 3 & group 4 as compared with the control group in both experimental group I & experimental group II. There were not any statistical difference from apitoxin and acupuncture therapy by Duncan's multiple range test. 4. The effect of apitoxin on hematocrit level showed noticeable decrease at group 3 & group 4 as compared with the control group in both experimental group I & experimental group II. The acupuncture was not showed decrease at group 3 & group 4 as compared with the control group in both experimental group I & experimental group II. There were not any statistical difference from apitoxin and acupuncture therapy by Duncan's multiple range test. 5. The effect of apitoxin on ASO titer showed noticeable decrease at group 3 & group 4 as compared with the control group only in experimental group I. The apitoxin & acupuncture showed decrease at group 3 & group 4 as compared with the control group in experimental group II. There were significantly statistical difference from apitoxin and acupuncture therapy by Duncan's multiple range test. The effect of apitoxin showed slightly decrease as compared with the acupuncture therapy by Duncan's multiple range test.

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The Spermatogenic Effect of 50% Ethanol Extracts of Yacon and Its Ameliorative Effect Against 2,3,7,8-tetrachlorodibenzo-p-dioxin Induced Testicular Toxicity in the Rat

  • Park, Jeong-Sook;Hwang, Seock-Yeon;Hwang, Bang-Yeon;Han, Kun
    • Natural Product Sciences
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    • 제14권2호
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    • pp.73-80
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    • 2008
  • The authors screened the pharmacological effects of 50% ethanol extracts of Yacon on spermatogenesis in rats. Numbers of sperm in animals treated with 25, 50, or 100 mg/kg/day for 6 weeks of Yacon tuber extracts (YTE) were approximately 1.51, 1.61 and 1.78 times higher, respectively, than in the untreated control group. Moreover, the spermatogenic effect of Yacon leaf extract was found to be $1.03{\sim}1.38$ times higher than that of YTE. The ameliorative effect of Yacon tuber extracts on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced toxicities in the rat were also investigated. Rats were assigned to three groups (6 rats/group), a control group, a TCDD exposed group, and a group treated with Yacon tuber extract (YTE) after TCDD exposure (TCDD/YTE group). 40 ${\mu}g/kg$ of TCDD was injected i.p., and 200 mg/kg/day of YTE was also administered for 4 weeks by oral gavage. The TCDD/YTE group showed a significant increase in sperm number as compared with the TCDD exposed group. In conclusion, TCDD induced testicular toxicity was significantly ameliorated by YTE. The results of the present study suggest that Yacon extract is a possible therapeutic for the treatment of spermatogenic disorder.

로얄제리가 Streptozotocin 유발 당뇨 흰쥐의 치료 및 예방에 미치는 영향 (Effect of Royal Jelly on Therapy and Prevention of Streptozotocin Induced Diabetic Rats)

  • 한준표;우주연;백경연
    • 한국식품영양과학회지
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    • 제27권6호
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    • pp.1267-1272
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    • 1998
  • In order to investigate the preventive and therapeutic of royal jelly on diabetes, the levels of blood glucose and serum lipids as well as the number of blood cells were determined in streptozotocin(STZ) diabetic rats. Rats were divided into seven groups. The RJ group was administered royal jelly and the STZ group was treated with streptozotocin to induce diabetes. To determine the preventive effect, diabetes was induced after administration of royal jelly for 2 weeks in group RS1/RS2. In group SR1/SR2 diabetic rats were administered royal jelly for 2 weeks to investigate the therapeutic effect. After 3 weeks, the body weight was reduced in STZ and SR1 groups and food intake was increased in the STZ, RS1 and SR1 groups. The blood glucose level was similar to the control group in the RJ, RS1 and RS2 groups and there was no effect in the other groups. The total lipid and triglyceride level were lower in the SR1 group as compared to STZ, and the total cholesterol level was higher in the STZ group. The index of atherogenesis was lower in the RJ and SR1 groups compared to the normal group. The number of red blood cells and hemoglobin was higher in the RJ and SR1 groups and the number of white blood cells was higher in the RJ and SR2 groups.

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광고를 활용한 환경교육이 유아의 환경친화적 태도 및 환경보전 지식에 미치는 효과 (A Study on the Effect of Environmental Education Using the Advertisement on Children's Eco-Friendly Attitude and Environmental Preservation Knowledge)

  • 임수민;안효진
    • Human Ecology Research
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    • 제54권5호
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    • pp.451-459
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    • 2016
  • This study was to develop environmental education activities using advertisement as well as investigate the effect of environmental education using advertisements on children's eco-friendly attitudes and environmental preservation knowledge. The effect of the environmental education activity using advisements was examined based on 24 children aged five attending a daycare center located in Incheon metropolitan city (12 in the experimental group and 12 in the control group). This study was executed 12 times (twice a week) in both the experimental group and comparative group as the environmental education using advertisements was developed and executed in the experimental group as environmental education according to the life theme's in the Nuri curriculum of the comparative group. The instruments used in this study were the children's eco-friendly attitude scale (two factors, 18 items) and environmental preservation knowledge scale (four factors, 16 items). Children's eco-friendly attitude and environmental preservation knowledge were assessed by pre-tests and post-tests using the SPSS ver. 18.0 program. Results indicated that after 6 weeks application, the experimental group exhibited higher scores than the control group in the children's eco-friendly attitude as well as environmental preservation knowledge. This study showed that environmental education activities using advertisement had a positive effect on children's eco-friendly attitudes and environmental preservation knowledge.