• The Korean journal of internal medicine
• /
• v.33 no.6
• /
• pp.1119-1128
• /
• 2018

Background/Aims: In multicenter clinical trials, laboratory tests are performed in the laboratory of each center, mostly using different measuring methodologies. The purpose of this study was to evaluate coefficients of variation (CVs) of laboratory results produced by various measuring methods and to determine whether mathematical data adjustment could achieve harmonization between the methods. Methods: We chose 10 clinical laboratories, including Green Cross Laboratories (GC Labs), the central laboratory, for the measurement of total cholesterol, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), serum triglycerides, creatinine, and glucose. The serum panels made with patient samples referred to GC Labs were sent to the other laboratories. Twenty serum samples for each analyte were prepared, sent frozen, and analyzed by each participating laboratory. Results: All methods used by participating laboratories for the six analytes had traceability by reference materials and methods. When the results from the nine laboratories were compared with those from GC Labs, the mean CVs for total cholesterol, HDL-C, LDL-C, and glucose analyzed using the same method were 1.7%, 3.7%, 4.3%, and 1.7%, respectively; and those for triglycerides and creatinine analyzed using two different methods were 4.5% and 4.48%, respectively. After adjusting data using Deming regression, the mean CV were 0.7%, 1.4%, 1.8%, 1.4%, 1.6%, and 0.8% for total cholesterol, HDL-C, LDL-C, triglyceride, creatinine, and glucose, respectively. Conclusions: We found that more comparable results can be produced by laboratory data harmonization using commutable samples. Therefore, harmonization efforts should be undertaken in multicenter trials for accurate data analysis (CRIS number; KCT0001235).

• Membrane Journal
• /
• v.34 no.1
• /
• pp.20-29
• /
• 2024

Membranes are increasingly used in a variety of applications including desalination, gas separation, disposable filters, and healthcare products. Recently, sustainable and green membrane fabrication technology is recognized as one of the decisive initiatives to reach the target of pollution control. Especially, the fabrication of bio-based membranes using such as poly lactic acid (PLA), polybutylene adipate terephthalate (PBAT), and polybutylene succinate (PBS) has attracted considerable attention. The phase inversion method is one of the versatile approaches for preparing PLA membranes. This article reviews the recent advances in PLA membrane preparation via the phase inversion method. Furthermore, it provides a perspective on the potential outlook for future advances. Overall, this review has demonstrated has been conducted in the area of bio-based PLA membranes.

• Journal of Environmental Science International
• /
• v.22 no.2
• /
• pp.131-138
• /
• 2013

In order to provide a scientific foundation for herb application in landscape, the photographs were taken from the herb landscape in urban green space and sightseeing garden. The questionnaire-based survey was also applied to analyze the cognitive situation of herb. Most investigators love herb, but have a low level of herb; Interviewees' consideration of herb function lie in ornamental, healthcare and medical treatment; The bulk of the visitors think herb landscape is insufficient; Investigators' preferences for herb application forms are landscape edging and combining with stone. We also probe into the optimum allocation form combining herb with landscape elements. When we combine herb with landscape water or landscape architecture, artistic conception and reasonable plant allocation should be considered; When we combine herb with landscape path or garden ornament, reasonable plant disposition and appearance and practical collocation should be thought over; When we combine herb with flower-border, richly colored landscape and reasonable plant allocation should be deliberated on.

• Journal of the Korea Safety Management & Science
• /
• v.13 no.2
• /
• pp.147-155
• /
• 2011

For an effective energy management in intelligent buildings it is necessary to gather information about position/absence of people and the level of population. In this paper the smart occupancy detection system based on the active RFID is developed to satisfy such a demand. The performance of the developed system is tested and verified through various experiments. Furthermore the feasibility test of the active RFID tag is performed to verify whether it can be used as a location-based occupancy sensor. The developed core technology can be also applied to other fields such as security, healthcare, smart home, etc.

• Journal of the Korea Safety Management & Science
• /
• v.14 no.4
• /
• pp.117-123
• /
• 2012

For an effective energy management in intelligent buildings it is necessary to gather information about position/absence of people and the level of population. In this paper the smart occupancy detection system using the active RFID is developed to satisfy such a demand based on the results of previous research. First of all the design considerations and functions of the system are introduced. In sequence the functions of the system is presented, and then the performance of the developed system is tested and verified through various field tests. The developed core technology can be also applied to other fields such as security, healthcare, smart home, etc.

• Korean Journal of Environment and Ecology
• /
• v.35 no.6
• /
• pp.669-678
• /
• 2021

This study surveyed three land cover types in Chungju City in Chungcheongbuk Province to check the distribution of cultured bacteria in bio-aerosols according to land cover type. It was possible to compare and analyze the distribution of bacteria according to microclimatic changes at each measurement point by examining meteorological factors and bio-aerosols according to land cover. The microclimate temperature in each measurement point was 8.7℃ for the urban forest, 10.8℃ for the waterside green area, and 10.2℃ for the urban area, indicating the urban forest had the lowest temperature among the measurement points. The relative humanity was 61.8% fin the urban forest, 59.3% in the waterside green area, and 55.7% in the urban area, indicating that the urban forest was the most humid among the measurement points. The identified bacteria were found to be 43 genera and 99 species. In terms of species diversity of cultured bacteria, 22 genera were found in the waterside green area, 21 genera in the urban forest, and 17 genera in the urban area, 37 species were found in the waterside green area, 31 species in the urban area, and 31 species in the urban forest. Bacillus toyonensis and Pseudarthrobacter oxydan were the species present in all three types of measurement sites, and Herbiconiux flava was confirmed to inhabit green areas such as urban forests and waterside green areas. The analysis result of the bacterial concentration according to the microclimatic environment in each measurement point was 333 CFU/m³ in the urban forest, 287 CFU/m³, in the waterside green area, and 173 CFU/m³ in the downtown area. The relative humidity and wind speed were analyzed to show a similar trend as the concentration. This study is expected to provide basic data for healthy urban management and green area creation by identifying the distribution of cultured bacteria in bio-aerosols according to land cover type and comparing and analyzing the traits of bio-aerosol in each measurement point.

• Journal of The Korea Institute of Healthcare Architecture
• /
• v.29 no.3
• /
• pp.29-36
• /
• 2023

Purpose: The purpose of this study is to find out whether the color change of the LED light source has a significant effect on the beta wave activity of EEG in the learning state. Methods: The subjects of the experiment were 20 male and female college students between the ages of 19 and 25 who routinely perform their studies. In the created learning environment, the EEG change according to the change in the lighting color was measured while solving the Mensa thinking ability problem while sitting on a desk with LED lights installed on the top and a chair with a footrest to stabilize the legs. The light source consisted of 3 ready-made colors and 6 newly created colors. A total of 9 color light stimuli were given for 2 minutes each, and the EEG change of the subject was observed. After the experiment, the correlation was analyzed based on the mid-beta wave data recorded on the QEEG according to the color change of light and the Mensa problem score. Results: It was found that the activation of mid-beta waves was stimulated in the temporal lobes (T5, T3, T6, T4) and occipital lobes (O1, O2) of all subjects who focused on solving Mensa thinking problems. As a result of comparing the top 20% and the bottom 20% of problem solving scores, the upper group had no effect of lighting, while the lower group showed increased beta wave activity in response to color light stimulation in the order of T4, T6, and T5. Implications: It was confirmed that the color of light that activates the middle beta wave varies greatly depending on the subject's attention and learning ability, and it is judged that the color of light including the green wavelength is helpful in activating the middle beta wave in the group with low learning ability.

• Science of Emotion and Sensibility
• /
• v.17 no.3
• /
• pp.29-38
• /
• 2014

The purpose of this study was to verify human physiological responses to emotional lighting system using LED (light emitting diode) flat lighting. Subjects were ten males in their twenties without medical history to eyes. Colors of LED lighting are red, orange, yellow, green, blue, purple and colorless (white). They were stimulated by LED lighting for 5 minutes. We measured body temperature, heart rate variability (HRV) and electroencephalogram (EEG) before and after color stimulus. In case of EEG analysis, relative power ${\alpha}$ wave ratio decreased in the groups of colorless, red and orange color light. Also, sympathetic nerve was more activated than parasympathetic nerve and the body temperature was increased in the groups of colorless, red, orange, yellow color light. On the other hand, relative power ${\alpha}$ wave ratio increased and parasympathetic nerve was more activated than sympathetic nerve and the body temperature was decreased in the groups of green, blue and purple color light. The results imply that the LED color lighting system in the realistic experiment environment. In the future, studies with compounded both colors and modes according to situation or auditory as nature sound or olfactory as aroma will be required.

• Korean Journal of Clinical Laboratory Science
• /
• v.37 no.3
• /
• pp.178-184
• /
• 2005

Carry over contamination has been reduced in some systems by flushing the internal and external surfaces of the sample probe with copious amount of diluent. It between specimens should be kept as small as possible. A built-in, continuous-flow wash reservoir, which allows the simultaneous washing of the interior and exterior of the syringe needles, addresses this issue. In addition, residual contamination can further be prevented through the use of efficient needle rinsing procedures. In discrete systems with disposable reaction vessels and measuring cuvets, any carry over is entirely caused by the pipetting system. In analyzers with reuseable cuvets or flow cells, carry over may arise at every point through which high samples pass sequentially. Therefore, disposable sample probe tips can eliminate both the contamination of one sample by another inside the probe and the carry over of in specimen into the specimen in the cup. The results of the applicative carry over experiment studied on 21 items for total protein (TP), albumin (ALB), total bilirubin (TB), alkaline phosphatase (ALP), aspratate aminotranferase (AST), alanine aminotranferase (ALT), gamma glutamyl transferase (GGT), creatinine kinase (CK), lactic dehydrogenase (LD), creatnine (CRE), blood urea nitrogen (BUN), uric acid (UA), total cholesterol (TC), triglyceride (TG), glucose (GLU), amylase (AMY), calcium (CA), inorganic phosphorus (IP), sodium (Na), potassium (K), chloride (CL) tests in chematology were as follows. Evaluation of process performance less than 1% in all tests was very good, but a percentage of ALB, TP, TB, ALP, CRE, UA, TC, GLU, AMY, IP, K, Na, and CL was 0%, implying no carry over. Other tests were ALT(-0.08%), GGT(-0.09%), CK(0.08%), LD(0.06%), BUN(0.12%), TG (-0.06%), and CA(0.89%).

• Journal of Digital Convergence
• /
• v.11 no.12
• /
• pp.577-588
• /
• 2013

Main purpose of this study is to suggest improvement of environmental information disclosure system and to find out counterplan for hospitals based on literal review and 41 hospitals/clinic's environmental information data(2011) released by the Korean ENV-INFO SYSTEM. The research methodology used to analyze 18 items divided between 7 for compulsory and 11 for voluntary was primarily quantitative. Research subjects was comprised of 33 general hospitals, 6 hospitals and 1 clinic. Environmental information disclosure system needs to be improved as follows: (1) enlargement of citizen participation, (2) upgrade of 'Company Overview', (3) clear definition of items, (4) unifying measure unit, (5) close verification, (6) creating standards for additional informations. The following activities are critical for hospitals: (1) reliability enhancement of hospital's data, (2) reorganization strategy & green management system, (3) water/energy reduction data accumulation, (4) greenhouse gas emission reduction planning, (5) introduction of green purchase guidelines, (6) digital publication of environmental(sustainable) report.