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Development and Thermal Distribution of An RF Capacitive Heating Device (유전가열장치의 개발과 온열분포)

  • Chu, Sung-Sil;Suh, Chang-Ok;Kim, Gwi-Eon;Loh, John-Kyu;Kim, Byung-Soo
    • Radiation Oncology Journal
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    • v.5 no.1
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    • pp.49-58
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    • 1987
  • Hypertermia for the treatment of cancer has been introduced for a long time and the biological effect for the use of hyperthermia to treat malignant tumors has been well established and encouraging clinical results have been obserbed. Unfortunately, however, the engineering or technical aspects of hyperthermia for the deep seated tumors has not been satisfactory. We developed the radiofrequency capactive hyperthermia device (Greenytherm-GY8) in cooperation with Yonsei Cancer Center and Green Cross Medical Corporation. It was composed with $8{\sim}10MHz$ RF generator, capacitive electrode, matching system, cooling system, temperature measuring system and control PC computer. The thermal profile was investigated in agar phantom, animals and in human tumors, heated with capactivie RF device. Deep and homogeneous heating could be achieved in a large phantom of 25cm diameter and 19cm thick when heated with a pair of 23cm diameter electrodes, coupled to both bases of the phantom, when the size of the two electrodes was not the same, the region near the smaller electrode was preferentially heated. It was, therefore, possible to control the depth of heating by choosing proper size of electrodes. Therapeutic temperature $(42^{\circ}C{\sim}43^{\circ}C)$ could be obtained in the living animal experiments. Indications are that deep heating of humn tumors might be achieved with the capacitive method, provided that subcutaenous fat layer is cooled by temperature controlled bolus and large size of electrodes.

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Shoes from Pinet to the Present

  • June, Swann
    • Proceedings of the Korea Society of Costume Conference
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    • 2001.08a
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    • pp.11-13
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    • 2001
  • For those unfamiliar with the shoe world, Pinet (1817-1897) was a contemporary of Worth, the great Parisian couturier. So I look at the glamour shoes and the world of haute couture, and indeed the development of the named designer. That is a concept we are all familiar with now. So it is not easy to comprehend the lack of names for the exquisite work before 1850. Straightway I have to say that the number of noted shoe designers is far fewer than famous dress designers, but I will introduce you to some of them, against the background of contemporary shoe fashions. Franc;ois Pinet was born in the provinces (probably Touraine) in 1817, two years after the end of the Napoleonic Wars. His father, an ex-soldier, settled to shoemaking, a comparatively clean and quiet trade. It had a tradition of literacy, interest in politics, and was known as the gentle craft, which attracted intelligent people. We should presume father would be helped by the family. It was usual for a child to begin by the age of 5-6, tying knots, sweeping up, running errands and gradually learning the job. His mother died 1827, and father 1830 when he was 13, and at the time when exports of French shoes were flooding world markets. He went to live with a master shoemaker, was not well treated, and three years later set out on the tour-de- France. He worked with masters in Tours and Nantes, where he was received as Compagnon Cordonnier Bottier du Devoir as Tourangeau-Ia rose dAmour (a name to prove most appropriate). He went on to Bordeaux, where at 19 he became president of the local branch. In 1841 he went to Paris, and in 1848, revolution year, as delegate for his corporation, he managed to persuade them not to go on strike. By now the shoemakers either ran or worked for huge warehouses, and boots had replaced shoes as the main fashion. In 1855 Pinet at the age of 38 set up his own factory, as the first machines (for sewing just the uppers) were appearing. In 1863 he moved to new ateliers and shop at Rue ParadisPoissoniere 44, employing 120 people on the premises and 700 outworkers. The English Womans Domestic Magazine in 1867 records changes in the boots: the soles are now wider, so that it is no longer necessary to walk on the uppers. There is interest in eastern Europe, the Polonaise boots with rosette of cord and tassels and Bottines Hongroises withtwo rows of buttons, much ornamented. It comments on short dresses, and recommends that the chaussure should correspond to the rest of the toilet. This could already be seen in Pinets boots: tassels and superb flower embroidery on the higher bootleg, which he showed in the Paris Exposition that year. I think his more slender and elegant Pinet heel was also patented then or 1868. I found little evidence for colour-matching: an English fashion plate of 1860 shows emerald green boots with a violetcoloured dress.

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Effects of Differential Heating by Land-Use types on flow and air temperature in an urban area (토지 피복별 차등 가열이 도시 지역의 흐름과 기온에 미치는 영향)

  • Park, Soo-Jin;Choi, So-Hee;Kang, Jung-Eun;Kim, Dong-Ju;Moon, Da-Som;Choi, Wonsik;Kim, Jae-Jin;Lee, Young-Gon
    • Korean Journal of Remote Sensing
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    • v.32 no.6
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    • pp.603-616
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    • 2016
  • In this study, the effects of differential heating by land-use types on flow and air temperature at an Seoul Automated Synoptic Observing Systems (ASOS) located at Songwol-dong, Jongno-gu, Seoul was analyzed. For this, a computation fluid dynamics (CFD) model was coupled to the local data assimilation and prediction system (LDAPS) for reflecting the local meteorological characteristics at the boundaries of the CFD model domain. Time variation of temperatures on solid surfaces was calculated using observation data at El-Oued, Algeria of which latitude is similar to that of the target area. Considering land-use type and shadow, surface temperatures were prescribed in the LDAPS-CFD coupled model. The LDAPS overestimated wind speeds and underestimated air temperature compared to the observations. However, a coupled LDAPS-CFD model relatively well reproduced the observed wind speeds and air temperature, considering complicated flows and surface temperatures in the urban area. In the morning when the easterly was dominant around the target area, both the LDAPS and coupled LDAPS-CFD model underestimated the observed temperatures at the Seoul ASOS. This is because the Kyunghee Palace located at the upwind region was composed of green area and its surface temperature was relatively low. However, in the afternoon when the southeasterly was dominant, the LDAPS still underestimated, on the while, the coupled LDAPS-CFD model well reproduced the observed temperatures at the Seoul ASOS by considering the building-surface heating.

Exposure Characteristics of Particles during the After-treatment Processes of Aluminum Oxide Fibers and Nickel Powders (산화알루미늄 섬유와 니켈분말 후처리공정에서 입자의 노출특성)

  • Kim, Jong Bum;Kim, Kyung Hwan;Ryu, Sung Hee;Yun, Seong-Taek;Bae, Gwi-Nam
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.26 no.2
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    • pp.225-236
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    • 2016
  • Objectives: Nanomaterials have been used in various fields. As use of nanoproducts is increasing, workers dealing with nanomaterials are also gradually increasing. Exposure assessments for nanomaterials have been carried out for protection of worker's health in workplace. Exposure studies were mainly focused on manufacturing processes, but these studies on after-treatment processes such as refinement, weighing, and packing were insufficient. So, we investigated exposure characteristics of particles during after-treatment processes of $Al_2O_3$ fibers and Ni powders. Methods: Mass-production of Ni powder process was carried out in enclosed capture-type canopy hood. In a developing stage, $Al_2O_3$ was handled with a local ventilation unit. Exposure characteristics of particles were investigated for $Al_2O_3$ fiber and Ni powder processes during the periods of 10:00 to 16:00, 20 May 2014 and 13:00 to 16:00, 21 May 2014, respectively. Three real-time aerosol instruments were utilized in exposure assessment. A scanning mobility particle sizer(SMPS, nanoscan, model 3910, TSI) and an optical particle counter(OPC, portable aerosol spectrometer, model 1.109, Grimm) were used to determine the particle size distribution in the size range of 10-420 nm and $0.25-32{\mu}m$, respectively. In addition, a nanoparticle aerosol monitor(NAM, model 9000, TSI) was used to measure lung-deposited nanoparticle surface area. Membrane filters(isopore membrane filter, pore size of 100 nm) were also used for air sampling for the FE-SEM(model S-5000H, Hitachi) analysis using a personal sampling pump(model GilAir Plus by 2.5 L/min, Gilian). Conclusions: For Ni powder after-treatment process, only 27% increase in particle concentration was found during the process. However, for $Al_2O_3$ fiber after-treatment process, significant exposure(1.56-3.34 times) was observed during the process.

Typing and Sequence Analysis of the VP7 Gene of Rotavirus Isolated from Infants in Korea (한국영아에서 분리된 로타바이러스의 VP7 유전자형 및 염기서열 분석)

  • Song, Mi-Ok;Yun, Karyn;Chung, Sang-In;Choi, Chul-Soon;Lim, In-Seok;Kang, Shien-Young;An, Chang-Nam;Kim, Won-Yong
    • The Journal of Korean Society of Virology
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    • v.30 no.2
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    • pp.101-112
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    • 2000
  • Rotaviruses are the most common cause of severe vomiting and diarrhea in children worldwide and classified as a genus in the family Reoviridae. Rotavirus has eleven segmented dsRNAs and the virion consists of three shells. Outer capsid VP7 and VP4 induce neutralizing antibodies and are classified into G types (glycoprotein VP7) and P types (protease-sensitive VP4). Characterization of VP7 gene of Korean isolates of human rotavirus was performed using multiplex PCR and nucleotide sequence analysis. After RT-PCR amplification of full length (1,062 bp) of VP7 genes, the amplified PCR products were G typed by multiplex PCR and the nucleotide sequences were compared with those of reference rotavirus from GenBank. The G type analysis revealed that 25% (2/8) belong to G1, whereas 37.5% (3/8) benong to G2 and G4, respectively. The Korean isolates within the same serotypes showed high homology of nucleotide sequences and could be discriminated from foreign isolates exception with two strains (CAU009 and CAU022). But Korean isolates CAU009 and CAU022 were close related into japanease isolates 417 (99.2%) and indian isolates (97.6%) than Korean isolatese. Our results showed that these two strains were supposed to be originated from abroad. As a results, The G typing and nucleotide sequence analysis of VP7 gene of rotavirus isolated from infants in Korea could be used for identification, serotying and determination of novel or unusual strains of rotaviruses.

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Effect of fruit extracts from Sorbus commixta Hedl. on the lipid metabolism in rats (마가목의 열매 추출물이 흰쥐의 지질대사에 미치는 영향)

  • Chung, Byung-Hee;Lee, Hyeon-Yong;Lee, Jin-Ha;Kim, Na-Young;Lee, Sung-Yul;Choi, Jin-Tae;Kim, Jae-Heun;Kim, Jong-Dai
    • Korean Journal of Medicinal Crop Science
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    • v.11 no.2
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    • pp.143-147
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    • 2003
  • This study was carried out to investigate the effect of Sorbus commixta Hedl. fruit extracts on the lipid metabolism in rats. Experimental groups were divided into 3 groups; Sprague-dawley rats were fed either diets containing 1% of water extracts(WE group), 1% methanol extracts(MeOH group) and diets without extracts(Control group) during 4 weeks. Food intake, weight gain and liver weight were not shown in meaning full difference among the groups. The concentration of serum triglyceride and total cholesterol were significantly decreased in WE and MeOH group compared to control group. Serum HDL-cholesterol, phospholipids and glucose contents were slightly lower in WE and MeOH group than control group. The levels of liver triglyceride was significantly decreased in MeOH group compared to control group. The levels of total cholesterol and phospholipids in liver were significantly lower in WE and MeOH group than control group.

Analyses of Valatile Compounds from Allium sup. and Ovipositional Response of Delia antiqua to Various Volatile Chemicals (Allium속 방향성 성분의 분석과 방향성 성분이 고자리파리(Delia antiqua) 산란에 미치는 영향)

  • Kim, Young-Hui;Jo, Hyeong-Chan
    • Applied Biological Chemistry
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    • v.44 no.1
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    • pp.12-19
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    • 2001
  • The major volatiles from Allium species were found to be sulfide compounds and the ratio of sulfide to volatiles was 66.1% in garlic, 66.1% in scallion, 62.3% in green onion, 39.2% in onion, and 4.2% in chive. Trace of cyclooctasulfur was found to be present among the volatiles. The most oviposition of 17.2% occurred at diallyl sulfide and the least of 0.8% at acetylthiophene whereas the most oviposition of 43.3% occurred at ethyl alcohol if concentration was 100%. Among the organic solvents used for dilution, ethyl alcohol received the highest 52.5% of oviposition and ether the lowest of 5.9%. Furfuryl mercaptan which is also one of the volatiles, received 46.9% of oviposition. For oviposition site, D. antiqua preferred sulfides at near 1%, ethyl alcohol at high, and other volatiles at various concentrations. At 100% concentration, most volatiles except dimethyl disulfide and ethyl alcohol received less oviposition than the control which was watered sand with no volatiles added.

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An Analysis of the water balance of Low Impact Development Techniques According to the Rainfall Types (강우 유형에 따른 저영향개발 기법별 물수지 분석)

  • Yoo, Sohyun;Lee, Dongkun;Kim, Hyomin;Cho, Youngchul
    • Journal of Environmental Impact Assessment
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    • v.24 no.2
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    • pp.163-174
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    • 2015
  • Urbanization caused various environmental problems like destruction of natural water cycle and increased urban flood. To solve these problems, LID(Low Impact Development) deserves attention. The main objective of LID is to restore the water circulation to the state before the development. In the previous studies about the LID, the runoff reduction effect is mainly discussed and the effects of each techniques of LID depending on rainfall types have not fully investigated. The objective of this research is to evaluate the effect of LID using the quantitative simulation of rainwater runoff as well as an amount of infiltration according to the rainfall and LID techniques. To evaluate the water circulation of LID on the development area, new land development areas of Hanam in South Korea is decided as the study site. In this research, hydrological model named STORM is used for the simulation of water balance associated with LID. Rainfall types are separated into two categories based on the rainfall intensity. And simulated LID techniques are green roof, permeable pavement and swale. Results of this research indicate that LID is effective on improvement of water balance in case of the low intensity rainfall event rather than the extreme event. The most effective LID technique is permeable pavement in case of the low intensity rainfall event and swale is effective in case of the high intensity rainfall event. The results of this study could be used as a reference when the spatial plan is made considering the water circulation.

Application of LID Methods for Sustainable Management of Small Urban Stream Using SWMM (SWMM 모델을 이용한 지속 가능한 도시 소하천 관리를 위한 LID 기법의 적용 방안 연구)

  • Han, Yanghui;Seo, Dongil
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.10
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    • pp.691-697
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    • 2014
  • Though the upper stream basin area of Gwanpyung-Cheon in Daejeon, Korea is protected as Green Belt Zone, the stream is under constant environmental pressure due to current agricultural practices and infrastructure development in its basin area. To develop appropriate integrated water resources management plan for the stream, it is necessary to consider not only water quality problems but also water quantity aspect. In this study, Storm Water Management Model (SWMM) was calibrated and validated with sets of field measurements to predict for future water flow and water quality conditions for any rainfall event. While flow modeling results showed good agreement by showing correlation coefficient is greater than 0.9, water quality modeling results showed relatively less accurate levels of agreements with correlation coefficient between 0.67 and 0.87. Hypothetical basin development scenarios were developed to compare effect on stream water quality and quantity when Low Impact Development (LID) technologies are applied in the basin. The results of this study can be used effectively in decision making processes of urban development Gwanpyung-Cheon area by comparing basin management alternatives such as LID methods.

Simulation of Agricultural Water Supply Considering Yearly Variation of Irrigation Efficiency (연단위 관개효율 변화를 고려한 관개지구 용수 공급량 모의)

  • Song, Jung Hun;Song, Inhong;Kim, Jin Taek;Kang, Moon Seong
    • Journal of Korea Water Resources Association
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    • v.48 no.6
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    • pp.425-438
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    • 2015
  • The objective of this study was to evaluate simulation of agricultural water supply considering yearly variation of irrigation efficiency. The water supply data of the Idong reservoir from 2001 through 2009 was collected and used for this study. Total 6 parameters including irrigation efficiency (Es), drainage outlet height, and infiltration, were used for sensitivity analysis, calibration, and validation. Among the parameters, the Es appeared to be the most sensitivity parameter. The Es was calibrated on a yearly basis considering sensitivity and time-varying characteristic, while other parameters were set to fixed values. The statistics of percent bias (PBLAS), Nash-Sutcliffe efficiency (NSE), and root means square error to the standard deviation of measured data (RSR) for a monthly step were 2.7%, 0.93, and 0.26 for the calibration, and 3.9%, 0.89, and 0.32 for the validation, correspondently. The results showed a good agreement with the observations. This implies that the modeling only with appropriate parameter values, apart from modeling approaches, can simulate the real supply operation reasonably well. However, the simulations with uncalibrated parameters from previous studies produced poor results. Thus, it is important to use calibrated values, and especially, we suggest the Es's yearly calibration for simulating agricultural water supply.