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Effect of fruit extracts from Sorbus commixta Hedl. on the lipid metabolism in rats  

Chung, Byung-Hee (School of Biotechnology & Bioengineering, Korea Nutrition Institute, Kangwon National University)
Lee, Hyeon-Yong (School of Biotechnology & Bioengineering, Korea Nutrition Institute, Kangwon National University)
Lee, Jin-Ha (School of Biotechnology & Bioengineering, Korea Nutrition Institute, Kangwon National University)
Kim, Na-Young (Department of Food and Nutrition, Kyoung Hee University)
Lee, Sung-Yul (Laboratory Agriculture Products Processing Regional Crop Experiment Station, Kangwondo)
Choi, Jin-Tae (Green Zone Corporation)
Kim, Jae-Heun (Forest Research Institute)
Kim, Jong-Dai (School of Biotechnology & Bioengineering, Korea Nutrition Institute, Kangwon National University)
Publication Information
Korean Journal of Medicinal Crop Science / v.11, no.2, 2003 , pp. 143-147 More about this Journal
Abstract
This study was carried out to investigate the effect of Sorbus commixta Hedl. fruit extracts on the lipid metabolism in rats. Experimental groups were divided into 3 groups; Sprague-dawley rats were fed either diets containing 1% of water extracts(WE group), 1% methanol extracts(MeOH group) and diets without extracts(Control group) during 4 weeks. Food intake, weight gain and liver weight were not shown in meaning full difference among the groups. The concentration of serum triglyceride and total cholesterol were significantly decreased in WE and MeOH group compared to control group. Serum HDL-cholesterol, phospholipids and glucose contents were slightly lower in WE and MeOH group than control group. The levels of liver triglyceride was significantly decreased in MeOH group compared to control group. The levels of total cholesterol and phospholipids in liver were significantly lower in WE and MeOH group than control group.
Keywords
Sorbus commixta Hedl.; Cholesterol; Triglyceride; Phospholipids; Glucose;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 AlordmannR, Ribierre C, Rouach H (1990) Ethanol induced Alcohol. 25:231-237
2 American Institute of Nutrition (1977) Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies. J. nutr., 107:1340   DOI
3 Kim HW (1998) Screening of antioxidants from Sorbus commixta Hedund and determination of its antioxidant activity. Kon-Kuk University
4 Sperry WM and Webb M (1950) A revision of the Schoenheimer-Sperry method of cholesterol determination. J. BioI. Chem., 187:97
5 Song YM, Tak YJ (1993) Factors related to serum total cholesterol. J. Korean Acad. Fam Med., 13(12):935-942
6 Fletcher MJ (1968) A colorimetric method for estimating serum triglycerides. Clin, Chim. Acta., 22:393   DOI   ScienceOn
7 Kim BN, Kim JD, Ham SS, Choi YS, LeeSY (1995) Effects of spice added Natto supplementation on the lipid metabolism in rats. J.Korean Soc, Food Nutr., 24:121
8 Roelof DM, Hielke DV,Jan FC (1985) t-Butanol extraction of feces : A rapid procedure for enzyme determination of fecal bile acids. Cholesterol metabolism in health and disease, 1:113
9 Borisov MI, Zhuravlev NS (1965) Flavonoids of the flowers of Sorbus aucuparia L. Famatsevtychnyi Zhumal, 20(3):50-52
10 Lee SM, Kim CE, Joe YI, Tahk HK (1972) Isolation of sorbic acid from the mountain ash berries. Korean J. Food SCI. Technology, 4(1):1-5
11 Lee MK, LeeHY, Lee JH.Oh JS, Kim JD (2002) Anticancer effect of Sorb us commixta Hedl. extracts. Korean J. Medicinal Crop Sci., 10(5):403-408
12 Folch J, lees M, Sloane-Stanley GH (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226:497
13 Plaa GI, Witsebi. H (1976) Chemicals, drugs and lipid peroxidation. Annu. Rev. Pharmacal. Toxical. 16:125-131   DOI   ScienceOn
14 Lim BU, Park DK, ShinEM, KimSH (2000) Effects of BuOH fractions isolated from Scutellaria baicalensis, Euginia aromaticz, Sorbus commixta, Betula mandshrica on anticody productivity, metabolism of unsaturated fatty acid and lipid h ydroperoxides. Korean J . Oriental Medical Pathology, 14(1): 171-182
15 Rouser G, Siakotos AN, Fleisher S (1966) Quantitative analysis of phosphorus analysis of sopts, Lipids, 1:85   DOI   PUBMED   ScienceOn