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Relationship between Alcohol Use Disorders Identification Test Fractional Anisotropy Value of Diffusion Tensor Image in Brain White Matter Region (알코올 선별 검사법(Alcohol Use Disorders Identification Test)과 뇌 백질 영역의 확산텐서 비등방도 계측 값의 관련성)

  • Lee, Chi Hyung;Kim, Gyeong Rip;Kwak, Jong Hyeok
    • Journal of the Korean Society of Radiology
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    • v.16 no.5
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    • pp.575-583
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    • 2022
  • Magnetic resonance diffusion tensor imaging (DTI) has revealed the disruption of brain white matter microstructure in normal aging and alcoholism undetectable with conventional structural MR imaging. we plan to analyze the FA measurements of the ROI of dangerous drinkers selected from Alcohol Use Disorders Identification Test (AUDIT) and Tract-Based Spatial Statics (TBSS) tool was used to extract FA values in the ROI from the image acquired through the pre-processing process. TBSS has a higher sensitivity of the FA value and MD value in the white matter than the brain gray matter, and has the advantage of quantitatively deriving the unlimited degree of brain nerve fibers, and more specialized in the brain white matter. We plan to analyze the fractional anisotropy (FA) measurement value for damage by selecting the center of the anatomical structure of the white matter region of the brain with high anisotropy among the brain neural networks that are particularly vulnerable to alcohol as the region of interest (ROI). In this study, we expected that alcohol causes damage to the brain white matter microstructure from FA value in various areas including both Choroid plexus. Especially, In the case of the moderate drunker, the mean value of FA in Lt, Rt. Choroid plexus was 0.2831 and 0.2872, whereas, in the case of the severe drunker, the mean value of FA was 0.1972 and 0.1936. We found that the higher the score on the AUDIT scale, the lower the FA value in ROI region of the brain white matter. Using the AUDIT scale, the guideline for the FA value of DTI can be presented, and it is possible to select a significant number of potentially severe drinkers. In other words, AUDIT was proved as useful tool in screening and discrimination of severe drunker through DTI.

Characteristics and Distribution Pattern of Carbonate Rock Resources in Kangwon Area: The Middle Carboniferous Yobong Formation in the Northern Part of Yeongwoleup, Kangwon, Korea (강원 지역에 분포하는 석회석 자원의 특성과 부존환경: 영월읍 북부 지역의 중기 석탄기 요봉층을 중심으로)

  • Park, Soo-In;Lee, Hee-Kwon;Lee, Sang-Hun
    • Journal of the Korean earth science society
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    • v.21 no.5
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    • pp.583-594
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    • 2000
  • The Middle Carboniferous Yobong Formation with North-South trending is distributed in the Yeongheungri and Samokri of Yeongwoleup, Kangwon Province, Korea. A light gray thick and massive pure limestone is developed in the middle part of the Yobong Formation and it has been exploited for a long time. This study was carried out to investigate the lithological characteristics and geochemical compositions of the limestones and to figure out how geologic structures control the disribution of the limestones of the formation. The limestones of the Yobong formation are characterized by the fine and dense textures and the light gray to light brown in color. The limestones are composed of crinoid fragments, small foraminifers, fusulinids, gastropods, ostracods, etc. Based on the amount of grains and matrix, the Yobong Limestone can be classified as fine packstones and wackestones. The chemical analysis of limestones of the Yobong Formation was carried out to measure the contents of CaO, MgO, Al$_2$O$_3$, Fe$_2$O$_3$ and SiO$_2$. The content of CaO ranges from 48.12 to 59.31% and its average is about 54.52%. The average content of MgO is about 0.32% and the coutents of Al$_2$O$_3$, Fe$_2$O$_3$ and SiO$_2$ are relatively low. The amounts of Al$_2$O$_3$, Fe$_2$O$_3$ and SiO$_2$ of the limestones vary according to the kinds of limestone and their stratigraphical horizons in the formation. Generally, the CaO content of the limestones of the Yobong Formation decreases towards the top of the formation. Using geometric and structural analysis, we determined five progressively overprinted phases of deformation recorded in the study area. The anticline and syncline formed during the first and fourth deformation had controlled the distribution pattern of the Yobong Limestone of the Yobong Formation. The structures of deformation D$_1$ consist of F$_1$ isoclinal folds and foliations. The D$_2$ deformation had formed the isoclinal interstratal F$_2$ folds and axial plane cleavages which are locally developed within mudstones. The structural elements of deformation D$_3$ are axial plane cleavages associated with recumbent F$_3$ folds. These structures are overprinted by meso-scale and regional F$_4$ folds which are regionally dominant. Finally, the structures of D$_5$ consist of the thrust faults and folds associated with the thrust faults.

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Geology and Landscape of Mt. Mudeung Province Park, Korea (무등산 도립공원의 지질과 경관)

  • Ahn, Kun-Sang
    • The Journal of the Petrological Society of Korea
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    • v.19 no.2
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    • pp.109-121
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    • 2010
  • Mt. Mudeung is located in Gwangju city, Damyang-Gun, Hwasun-Gun and its round form give us the mood of soft and rich. Its location is $126^{\circ}06'-127^{\circ}01'E$ and $35^{\circ}06'-35^{\circ}10'N$ and its highest peak is Cheonwang-bong with the height of 1,187 m. The Gwangju city is located in the West of Mt. Mudeng and the mountain range with a small basin in its East. The pavilion such as the Soswaewon, Songganjeong, Sigyongjeong are distributed along the stream in the north of Mt. Mudeung. The mountain is formed from the volcanic activity, Gwangju cauldron during the Cretaceous. The top part of Mt. Mudeung is composed of dark gray quartz-andesite and its K-Ar whole rock age is $48.1{\pm}1.7Ma$. The composition of the north area, where the Wonhyosa temple is located, is micrographic granite, whereas the composition of south area is rhyolite mainly. The main ridge of Mt. Mudeung runs from North, starting from the Bukbong, to south, passing Cheonwangbong, Jangbuljae and ending Anyangsan. Geologic feature of the mountain includes volcanic landform, mountaineous landform, and stream landform. The Seosukdae, Ipseokdae, Gyubongam, which are main ridges and formed from volcanic activity, are composed of mainly columnar joint. Saeinbong and Majipbong in the south-west are composed of mainly cliff and dome. The typical erosion landform of the mountain has three different types of the weathering-cave, each of which reflect the property of the original rock. Four different area of wide block stream, they makes the geological feature of spring-water, though its scale is small compared to that of water fall.

A Study on an Open/Closed Eye Detection Algorithm for Drowsy Driver Detection (운전자 졸음 검출을 위한 눈 개폐 검출 알고리즘 연구)

  • Kim, TaeHyeong;Lim, Woong;Sim, Donggyu
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.7
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    • pp.67-77
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    • 2016
  • In this paper, we propose an algorithm for open/closed eye detection based on modified Hausdorff distance. The proposed algorithm consists of two parts, face detection and open/closed eye detection parts. To detect faces in an image, MCT (Modified Census Transform) is employed based on characteristics of the local structure which uses relative pixel values in the area with fixed size. Then, the coordinates of eyes are found and open/closed eyes are detected using MHD (Modified Hausdorff Distance) in the detected face region. Firstly, face detection process creates an MCT image in terms of various face images and extract criteria features by PCA(Principle Component Analysis) on offline. After extraction of criteria features, it detects a face region via the process which compares features newly extracted from the input face image and criteria features by using Euclidean distance. Afterward, the process finds out the coordinates of eyes and detects open/closed eye using template matching based on MHD in each eye region. In performance evaluation, the proposed algorithm achieved 94.04% accuracy in average for open/closed eye detection in terms of test video sequences of gray scale with 30FPS/$320{\times}180$ resolution.

Effects of MK-801, CNQX, Cycloheximide and BAPTA-AM on Anoxic Injury of Hippocampal Organotypic Slice Culture (해마 조직 절편 배양을 이용한 무산소 손상에 대한 MK-801, CNQX, Cycloheximide 및 BAPTA-AM의 효과)

  • Moon, Soo-Hyeon;Kwon, Taek-Hyon;Park, Youn-Kwan;Chung, Heung-Seob;Suh, Jung Keun
    • Journal of Korean Neurosurgical Society
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    • v.29 no.8
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    • pp.1008-1018
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    • 2000
  • Objective : Glutamate induced excitotoxicity is one of the leading causes of cell death under pathologic condition. However, there is controversy whether excitotoxicity may also participate in the neuronal death under low intensity insult such as simple hypoxia or hypoglycemia. To investigate the role of NMDA receptor in low intensity insult, we chose anoxia as the method of injury and used organotypically cultured hippocampal slice as the material of experiment. Materials & Methods : The hippocampal slices cultured for 2-3 weeks were exposed to 60 minutes of complete oxygen deprivation(anoxia). Neuronal death was assessed with Sytox stain. Corrected optical density of fluorescence in gray scale, used as cellular death indicator, was obtained from pictures taken at 24 and 48 hours following the insult. The well-known in vivo phenomenon of regional difference in susceptibility of hippocampal sub-fields to ischemic insult was reproduced in HOSC(hippocampal organotypic slice culture) by complete oxygen deprivation injury. Results : $CA_1$ was the most vulnerable to complete oxygen deprivation in hippocampus while $CA_3$ was resistant. Oxygen deprivation for 10 and 20 minutes with glucose(6.5g/l) present was insufficient to induce neuronal death in the cultured hippocampal slice. However, after 30 minutes exposure under anoxic condition, neuronal death was able to be detected in the center of $CA_1$ area. The intensity and area of fluorescence indicating cell death correlated with the duration of oxygen deprivation. NMDA receptor and non-NMDA receptor blocking with MK-801(30 & $60{\mu}M$) and CNQX($100{\mu}M$) did not provide cellular protection to HOSC against damage induced by oxygen deprivation, but increased intracellular calcium buffering capacity with BAPTA-AM($10{\mu}M$) was effective in preventing neuronal death (p=0.01, Student's t-test). Cycloheximide($1{\mu}g/ml$, $10{\mu}g/ml$) provided no protection to HOSC against insult of complete oxygen deprivation for 60 minutes and combined therapy of MK-801(30 & $60{\mu}M$) and cycloheximide(1 & $10{\mu}g/ml$) was also ineffective in preventing neuronal death. Conclusion : The results of this study show that the another mechanism not associated with glutamate receptor(NMDA & non NMDA) may play major role in cell death mechanisms induced by complete oxygen deprivation and increased intracellular calcium during anoxia may participate in the neuronal death mechanism of oxygen deprivation. Further investigation of the calcium entry channel activated during oxygen deprivation is necessary to understand the neuronal death of anoxia.

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A Mouse Model of Photochemically Induced Spinal Cord Injury

  • Piao, Min Sheng;Lee, Jung-Kil;Jang, Jae-Won;Kim, Soo-Han;Kim, Hyung-Seok
    • Journal of Korean Neurosurgical Society
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    • v.46 no.5
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    • pp.479-483
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    • 2009
  • Objective : A mouse model of spinal cord injury (SCI) could further increase our basic understanding of the mechanisms involved in injury and repair of the nervous system. The purpose of this study was to investigate whether methods used to produce and evaluate photochemical graded ischemic SCI in rats, could be successfully adapted to mice, in a reliable and reproducible manner. Methods : Thirty female imprinting control region mice (weighting 25-30 g, 8 weeks of age) were used in this study. Following intraperitoneal injection of Rose bengal, the translucent dorsal surface of the T8-T9 vertebral laminae of the mice were illuminated with a fiber optic bundle of a cold light source. The mice were divided into three groups; Group 1 (20 mg/kg Rose bengal, 5 minutes illumination), Group 2 (20 mg/kg Rose bengal, 10 minutes illumination), and Group 3 (40 mg/kg Rose bengal, 10 minutes illumination). The locomotor function, according to the Basso-Beattie-Bresnahan scale, was assessed at three days after the injury and then once per week for four weeks. The animals were sacrificed at 28 days after the injury, and the histopathology of the lesions was assessed. Results : The mice in group 1 had no hindlimb movement until seven days after the injury. Most mice had later recovery with movement in more than two joints at 28 days after injury. There was limited recovery of one joint, with only slight movement, for the mice in groups 2 and 3. The histopathology showed that the mice in group 1 had a cystic cavity involving the dorsal and partial involvement of the dorsolateral funiculi. A larger cavity, involving the dorsal, dorsolateral funiculi and the gray matter of the dorsal and ventral horns was found in group 2. In group 3, most of the spinal cord was destroyed and only a thin rim of tissue remained. Conclusion : The results of this study show that the photochemical graded ischemic SCI model. described in rats, can be successfully adapted to mice, in a reliable and reproducible manner. The functional deficits are correlated an increase in the irradiation time and, therefore, to the severity of the injury. The photothrombotic model of SCI, in mice with 20 mg/kg Rose bengal for 5 minutes illumination, provides an effective model that could be used in future research. This photochemical model can be used for investigating secondary responses associated with traumatic SCI.

A Study on Sensibility Image of Necktie according to Width and Color Combination of Checked Pattern (체크패턴의 폭과 색채조합에 따른 넥타이의 감성이미지 연구)

  • Choi, Su-Koung;Jung, Su-Jin;Sung, Nam-Suk
    • Science of Emotion and Sensibility
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    • v.12 no.4
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    • pp.545-556
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    • 2009
  • The purpose of this study was to investigate the sensibility image of necktie according to width and color combination of checked pattern. The experimental materials developed for this study were a set of stimulus and response scales. The stimuli were 18 color pictures, in which the width(small: 0.2cm, medium: 1cm, large: 2cm), tone combination(similar, contrast), and hue combination(WR: white+red, WB: white+blue, WG: white+gray) were manipulated. The 7-point scale was used for evaluation of sensibility image. The subjects of this research were 216 female college students living in Gyeongnam. The investigation was carried out at September 2009. The data were analyzed by using SPSS program. Analysis methods were ANOVA and Duncan-test. The results of this study were as follows.; The analyses of sensibility for necktie according to width and color combination of checked pattern revealed that the concerned factors are five characteristic dimensions of attractiveness, youth, appeal, elegance, and warmness. Width showed an independent effect on appeal. Tone combination showed an independent effect on attractiveness, appeal, elegance, and warmness. Interaction effects of width and tone combination on attractiveness were found. Hue combination showed an independent effect on all dimensions. In addition, significant interaction effects of width and hue combination on attractiveness, youth, appeal, and elegance were found. Significant interaction effects of tone combination and hue combination on attractiveness, youth, and appeal were found.

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Log-Polar Image Watermarking based on Invariant Centroid as Template (불변의 무게중심을 템플릿으로 이용한 대수-극 좌표계 영상 워터마킹 기법)

  • 김범수;유광훈;김우섭;곽동민;송영철;최재각;박길흠
    • Journal of KIISE:Computing Practices and Letters
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    • v.9 no.3
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    • pp.341-351
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    • 2003
  • Digital image watermarking is the method that can protect the copyright of the image by embedding copyright information, which is called watermark. Watermarking must have robustness to intentional or unintentional data changing, called attack. The conventional watermarking schemes are robust to waveform attacks such as image compression, filtering etc. However, they are vulnerable to geometrical attacks such as rotation, scaling, translation, and cropping. Accordingly, this paper proposes new watermarking scheme that is robust to geometrical attacks by using invariant centroid. Invariant centroid is the gravity center of a central area in a gray scale image that remains unchanged even when the image is attacked by RST including cropping and proposed scheme uses invariant centroids of original and inverted image as the template. To make geometrically invariant domain, template and angle compensated Log -Polar Map(LPM) is used. Then Discrete Cosine Transform(DCT) is performed and the watermark is embedded into the DCT coefficients. Futhermore, to prevent a watermarked image from degrading due to interpolation during coordinate system conversion, only the image of the watermark signal is extracted and added to the original image. Experimental results show that the proposed scheme is especially robust to RST attacks including cropping.

Changes in the Soil Physical Properties of Vineyard Converted from Paddy Field (논에서 전환한 포도원의 토양물리적 특성변화)

  • Yun, Eul-Soo;Jung, Ki-Youl;Park, Ki-Do;Ko, Jee-Yeon;Lee, Jae-Saeng;Park, Sung-Tae
    • Korean Journal of Soil Science and Fertilizer
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    • v.42 no.3
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    • pp.145-151
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    • 2009
  • This study was conducted to develop rational soil management and enhance the productivity of lands converted from paddy soils. Specifically, the changes in the soil physical properties brought about by the change in land usage from paddy soil were evaluated. This was carried out from 1999 to 2001 at 50 site in large-scale converted paddy fields of Kimcheon, Youngcheon, Gyeongsan and Milyang in the Youngnam region, categorized according to soil texture and drainage class. The ridge height of converted paddy soils was higher in coarse-textured and poorly-drained soils than in fine-textured and well-drained soils. The gray color of the surface soil was of lesser degree in converted soils than paddy soils and more notable in welldrained soils. The porosity ratio and the formation of aggregate structure were higher, and the appearance of soil mottling was deeper in converted paddy fields than in paddy soils. The glaying layer "g" of surface soil degraded with time. The porosity and amount of water stable aggregate was found to increase with time after conversion. The penetration resistance of the converted paddy soil was lower and deeper with time after conversion. The soil aeration of the converted paddy soil was lower in sandy loam than in loamy soil. Furthermore, soil aeration was influenced by ridge height and drainage class in poorly-drained soils.

Quantification of rock deformation using wavy extinction of quartz grain (석영의 파동소광 강도를 이용한 암석 변형의 정량화)

  • 정원석;나기창;정상원
    • The Journal of the Petrological Society of Korea
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    • v.11 no.2
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    • pp.65-73
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    • 2002
  • The wavy extinction of quartz grains can be used as a good indicator to show the degree of rock deformation. To determine degree of the rock deformation, intensity of wavy extinction (IWE) of quartz grains was measured by using polarizing microscope, digital camera, and NIH image (or Scion Image). In this experiment, the measurement was performed along the line perpendicular to the subgrain boundary of wavy extinction. IWE was measured when a quartz grain shows maximum extinction in polarizing microscope. NIH image was represented in terms of 256 gray-scale brightness, which was associated with intensity of the wavy extinction. IWE was determined by the degree of brightness versus the measuring length of a quartz grain. IWE was analysed in the distribution chart with the collection unit of 5. Regarding the characteristics of data distribution, the median between the mode and the median of the histogram is defined as a representative value for the IWE, and this value is subdivided into the five levels of rock deformation zones (lowest- or non-, low-, medium-, high-, and highest deformation) with their respective indices (D1, D2, D3, D4, and D5). The correlation between the Eonyang Granite and the Yangsan Fault was investigated by using the indices. The results indicate that IWE values decreased away from the fault.