• Title/Summary/Keyword: Grading

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Korean Prostate Cancer Patients Have Worse Disease Characteristics than their American Counterparts

  • Kang, Dong Il;Chung, Jae Il;Ha, Hong Koo;Min, Kweonsik;Yoon, Jangho;Kim, Wansuk;Seo, Won Ik;Kang, Pil Moon;Jung, Soo Jin;Kim, Isaac Yi
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6913-6917
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    • 2013
  • Background: Although the PSA test has been used in Korea for over 20 years, the incidence of prostate cancer has risen, and the associated mortality has increased about 13-fold over the 20-year period. Also, several investigators have suggested that Asians in America are more likely to present with more advanced prostate cancer than Caucasians. We compared the characteristics of native Koreans and Americans (Caucasians and African-Americans) undergoing radical prostatectomies in Korea and the US. Materials and Methods: Study subjects comprised patients at Korean and US hospitals from 2004 to 2012 who had undergone radical prostatectomies. We compared the characteristics of the subjects, including age, preoperative prostate-specific antigen (PSA) levels, body mass index (BMI), Gleason score, and pathological T stage. Results: In total, 1,159 males (502 Koreans, 657 Americans) were included. The Korean and American patients had mean ages of $67.1{\pm}6.6$ and $59.2{\pm}6.7$ years, respectively. The mean preoperative PSAs were $15.4{\pm}17.9$ and $6.2{\pm}4.6ng/mL$ (p=0.0001) and the mean BMIs were $23.6{\pm}2.6$ and $28.7{\pm}4.4kg/m^2$ (p=0.0001), respectively. Pathological localized prostate cancer represented 71.7% of cases for Koreans and 77.6% for Americans (p=0.07). According to age, Koreans had higher T stages than Americans in their 50s (p=0.021) and higher Gleason scores than Americans in all age groups. According to PSA, Koreans had higher Gleason scores than Americans for PSA >10 ng/mL (p<0.05). According to prostate size and Gleason scores, Koreans had higher PSA values than Americans (p<0.01). Conclusions: These results show that Korean patients have elevated risk of malignant prostate cancers, as indicated by the significantly higher Gleason scores and PSAs, suggesting a need for novel prostate cancer treatment strategies in Korea.

A Visual Study of the Quality of English Pronunciation Using the Praat Program (Praat을 활용한 영어발음특성의 시각적 연구)

  • Park, Heesuk
    • Journal of Digital Contents Society
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    • v.14 no.3
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    • pp.323-331
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    • 2013
  • This study aims at investigating and comparing the diphthongs, words, and sentences between two Korean highschool students groups using the Praat program. To do this English words and sentences were uttered and recorded by twenty Korean subjects; each group has ten subjects. All the subjects are female and their grades range from freshman to sophomore. Acoustic features were measured from a sound spectrogram with the help of the Praat software program and analyzed through statistical analysis. Results showed that the lengths of diphthongs and words were different between two groups, but the difference was not significant. However, in the lengths of sentence utterance, the group of 5 to 6 grade students in the current grading system pronounced longer than that of 1 to 2 grade students. Especially in the pronunciation of the first two sentences with more than five words, the difference was significant. From the data of the overall sum of words between the two subject groups, we were able to find out that the differences of the lengths of the words with the diphthongs were not significant, but those of the sentences with more than five words were significant. In the pronunciation of the words between coat and code, the length of the diphthong in coat was smaller than that of in code.

Needs for Integrated Care for Older Adults in Seoul (서울특별시 지역사회 거주 노인의 통합돌봄 요구)

  • Kim, Hyeongsu;Ko, Young;Son, Miseon
    • Journal of Convergence for Information Technology
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    • v.10 no.5
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    • pp.177-187
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    • 2020
  • The purpose of this study was to classify the care needs of the older adults aged 65 and over and to identify characteristics of care need groups. This was a secondary analysis study using data from 2017 National Survey of Older Persons in Seoul. There were 50.4% in the general group without any support needs, 17.9% in the medical needs group, 14.2% in the welfare needs group with support needs of daily living or social activity, and 17.5% in the complex needs group with both medical and welfare needs. Significant differences were shown in most variables of the general characteristics, grading of long-term care or disability, financial burden and caregiving, health behaviors, health status, and life satisfactions among groups (p<.001). The complex care need group should be provided with integrated care service for medical and welfare through multidisciplinary team approach.

Determinants of Economic Threshold for Powdery Mildew on Cucumber (오이 흰가루병의 경제적 피해 허용수준 설정)

  • Kim, Jin-Young;Hong, Soon-Sung;Lee, Jin-Gu;Park, Kyeong-Yeol;Kim, Hong-Gi;Kim, Jin-Won
    • Research in Plant Disease
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    • v.12 no.3
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    • pp.231-234
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    • 2006
  • The influences of powdery mildew caused by Sphaerotheca fusca were assessed on cucumber to verify the economic injury level and yield response. Based on the relation of disease severity and yield response, economic threshold was determined by grading the disease severity of powdery mildew. Yield loss simulation due to damage of powdery mildew was conducted by defoliation of lower cucumber leaves in two seasons. The minimum number of leaves was 10 in spring season and 13 in autumn season which made no distinct difference on cucumber yield. The whole yields of cucumber was reduced as the disease severity was increased. Therefore occurrence of powdery mildew have a negative effect on cucumber yield. The regression equation between disease severity and yield loss showed Y=-57.237x+6143.1, $R^2=0.9628$. This equation suggests the disease severity of economic threshold is 17.6%, which is 3% reduction point of yield based on yield and economic relations. These results suggest that application of fungicide should be needed when 1 or 2 leaves of cucumber are infected by powdery mildew in the growing season.

The legal status of the breast in assessing physical disability (신체장애 평가에서 유방의 법적 지위 - 장기 해당 여부, 수유장애, 노동력상실에 대하여 -)

  • Kim, Bong Kyum
    • The Korean Society of Law and Medicine
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    • v.18 no.1
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    • pp.265-295
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    • 2017
  • Breast tissue is composed of skin, mammary gland(including lactiferous duct), subcutaneous fat layer. The anatomical position is on the anterior chest wall(the outside of the chest cavity) but not on the inside of the thorax. Therefore, when the internal organs in the thoracic cavity are defined and expressed as 'organs' and the internal organs of each are labeled for a long time, for the breast located outside the thoracic cavity, it is thought that there is considerable difficulty in defining and recognizing the breast tissue as organs. For this reason, it is necessary to discourage the controversy over whether or not the breast is contained in the chest(or intra-thoracic cavity). In order to completely exclude it, it is assumed that the "chest-abdomen" can be called the "intra-thoraxic or intra-abdominal." But it is difficult to change the terms in various laws and regulations, I think that it would be necessary to insert only the clue clause "Breasts are excluded" in the detailed criteria for grading. In order to include it, it is necessary to change the terms of the ordinance or to say that the breast is exceptionally included.

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A Clinical Evaluation of the Tumor Volume Doubling Time in Primary Bronchogenic Carcinoma (폐암환자에서 본 Tumor Doubling Time 의 임상적 의의)

  • 홍기우;이홍균
    • Journal of Chest Surgery
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    • v.6 no.1
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    • pp.15-22
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    • 1973
  • The definition of cancer, its diagnosis and its prognosis all depend upon description of growth. To the layman a synonym for cancer is a "growth". There are no quantitative terms for the description of growth or growth rate in clinical use. There has been no attempt to assign values that would define "rapidly" or "slowly" growing. Estimates of growth potentiality are implied in the descriptive phrases "poorly differentiated" or "well differentiated", "highly malignant" or "low grade malignancy". and in systems of grading. These qualifying terms represent a personal impression, clinically useful in prognosis, but relative in nature. They do not lend themselves to uniform application or precise measurement for purpose of comparison. Growth is related to size and time. The volume of tumor depends upon the duration of the period of growth and the rate of growth. If the interval and change in volume are known. the average growth rate can be determined. If the growth rate is determined, and assumed to be constant., the duration of a given tumor and the time of inception can be estimated. The commonest concept of the origin of cancer is that as a result of a mutation involving a single cell, succeeding divisions of cells establish a colony with the characteristics recognizable as cancer. If the growth rate of the hypothetical tumor were constant it could be described in terms of "tumor volume doubling time". In the department of thoracic surgery of St. Mary hospital in Catholic Medical College, a clinical evaluation for the growth rate, degree of malignancy, resectability and prognosis was done on a total 24 cases of primary bronchogenic carcinoma which contour was significant on the chest X-ray film as possible estimating the tumor volume doubling time. The following results were obtained: 1. In the cases of 6.0cm or more in diameter of minor size at operation the resectability rate was lower and in the cases of 60 days or more in the tumor or volume doubling time the resectability rate was higher. 2. If differentiation of cancer cells was lower graded in tissue pathology, the tumor volume was shorter and the resectability rate was lower. 3. The tumor volume doubling time of the primary bronchogenic carcinoma occured more over 60 years of age was slightly shorter than under 60 years of age. 4. The tumor size at operation was more important to evaluate the survival time and prognosis than the tumor volume doubling time because the tumor growth was not always constant, we presume.mor volume doubling time because the tumor growth was not always constant, we presume.

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Policy Network Analysis on the Legislation Process of Internet Contents Regulation (인터넷내용규제 입법과정에 관한 정책네트워크 분석)

  • Song Sung-Soo;Kwon Gi-Chang
    • Journal of Science and Technology Studies
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    • v.4 no.1 s.7
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    • pp.83-110
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    • 2004
  • This article examines the legislation process of internet contents regulation through three phases from a policy network point of view. In the first phase, heated debates were initiated during the public hearings after the Ministry of Information & Communications announced its plan to introduce the internet contents grading system During the second phase, bills were submitted to the Standing Committee of the National Assembly, where the bills were deliberated, passed, and promulgated. In the third phase, issues on enforcement ordinance were resolved as the degree of conflict was mitigated. Policy network during the first phase started in a conflicting and distributed form, but has evolved into a conflicting and centralized form. The appropriate closure of the debate on the internet contents regulation can be explained by the structure of governmental departments, the character of new technology, and the mobilization of general public.

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Diagnostic Efficacy of PET in Soft Tissue Tumors: Comparative Study with Conventional Methods (연부 조직 종양에서 PET의 유용성: 기존의 진단법과의 비교 연구)

  • Seo, Sung-Wook;Park, Sang-Min;Cho, Hwan-Seong
    • The Journal of the Korean bone and joint tumor society
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    • v.11 no.1
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    • pp.32-39
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    • 2005
  • Introduction: Currently, F-18 fluorodeoxyglucose positron emission tomography scans (FDG-PET) has been investigated in soft tissue tumor especially for tumor detection and noninvasive grading. However, the validity and the efficacy of FDG-PET are still unclear in clinical evaluation. The purpose of this study is to determine the efficacy of FDG-PET in compared to conventional diagnostic imaging studies currently used in the soft tissue tumor. Methods: Between March 2001 and March 2002, 29 patients (sixteen males, thirteen females, mean age, 47 years; a range from 4 to 73) diagnosed with soft tissue tumor were evaluated by both conventional diagnostic imaging and FDG-PET. Valid reference test of the local lesion was the histopathologic diagnosis, which was measured in all patients. The suspecting metastasis in the imaging studies was validated by pathology or follow up imaging for at least 6 months. Each imaging diagnosis was made independently. The accuracy of each diagnostic method was evaluated. The incremental cost accuracy ratio was determined in each diagnostic method. Results: For detection of local lesion, sensitivity, specificity, and accuracy for MRI and FDGPET scans were 91%, 57%, 83% and 95%, 43%, 83% respectively. For detection of distant lesion, sensitivity, specificity, accuracy for conventional diagnostic methods and FDG-PET scans were 77%, 89%, 87% and 92%, 94%, 93% respectively. The incremental cost accuracy ratio (ICAR) of FDG-PET for detection of distant lesion was 145,000won/%. According to ICAR for each tumor grade, PET strategy is most cost-effective at high grade tumors. Conclusions: For detection of local lesion such as recurrence or remnant tumor, FDG-PET scan was not more accurate than MRI. However, It was more accurate for detection of metastatic lesion than conventional methods. For detection of high grade tumor, PET was most costeffective than for detection of lower grade tumor.

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Demographic Characteristics of Korean Men A Study on Correlation with Preference for Female Hair Style (한국 남성의 인구통계학적 특성 요인과 여성 헤어스타일에 대한 선호도와의 상관성 연구)

  • Son, Gwang Hyun;Park, Jang Soon
    • Journal of the Korea Convergence Society
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    • v.9 no.9
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    • pp.263-270
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    • 2018
  • The purpose of this study is to investigate the correlation between the demographic characteristics of Korean men and the preference of women's grading such as age, education, marital status, occupation, monthly income, and residence. After the questionnaire distribution, 333 questionnaires were analyzed statistically. Through this study, we will investigate the preference of men according to the step length of women's graduation cuts, and contribute to the establishment of the most preferred type of graduation cuts. As a result of the questionnaire analysis, 51.1% of all males preferred the gradation type with a large step of the cut length, and it was found that there was a difference in the preference for the step according to demographic characteristics (p <0.05) It is possible to conduct various studies on the style of the graduation cut among the hairstyles of women who are visually preferred and beautiful. In addition, it will be possible to derive the importance of customer satisfaction in hair salons, and it will be a basic index for searching for changes in the gradation cuts that can be applied in various ways while maximizing the aesthetic image of women.

Strengthening the Instruction-Assessment Alignment: Development of Items for Essay-Type Assessment Based on the Achievement Standards (수업과 평가 일체화를 위한 성취기준 중심 가정과 서술형 평가 문항개발 연구)

  • Yang, Ji Sun;Lee, Gyeong Suk
    • Journal of Korean Home Economics Education Association
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    • v.32 no.3
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    • pp.135-159
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    • 2020
  • The purpose of this study was to develop items of an essay response assessment that could align with the instructions and assessments in the high school home economics curriculum. The contents of the study were as follows. First, to establish an assessment plan, 14 achievement standards were analyzed in the assessment area, and the elements of the questions were developed including the content elements of a total of 29 questions. Second, to develop the assessment tools, preliminary questions suited to the structure of essay questions were developed, and the method of presenting data and scoring criteria to be utilized in the questions was selected. Third, to prepare the answers and the scoring criteria tables, the answers to the sample questions for each score were prepared in form of a scoring criteria table, and the objectives of the assessment, the scoring items, and the scores for each item were reviewed. Fourth, the developed questions and answers were revised and supplemented by teachers of the professional learning community through preliminary and mutual review on the components of the questions, the embodiment of the assessment objectives, the implementation of the assessment intent, and the grading. This study can be used as a foundational study for the development of essay-type questions and scoring criteria in essay assessment in the field of education. Furthermore, the results of this study could help teachers enhance their learners' ability to apply knowledge in the future.