• Childhood Kidney Diseases
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• v.13 no.2
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• pp.229-234
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• 2009

Purpose : The aim of this study was evaluating the efficacy of endoscopic $Deflux^{(R)}$ submucosal injection in children with primary vesicoureteral reflux (VUR). Methods : Retrospective analysis of medical record was conducted on 38 children (59 ureters) who underwent endoscopic $Deflux^{(R)}$ injection due to primary VUR. Data were collected from March 2000 to February 2006. Mean infused amount of $Deflux^{(R)}$ was 0.77 cc. After $Deflux^{(R)}$ injection, patients were reassessed by voiding cystourethrogram (VCUG) 6 months later. Results : The success rate of endoscopic $Deflux^{(R)}$ submucosal injection 6 months later by VCUG was 100% for grade 1 VUR, 87.5% for grade 2, 60% for grade 3, 26.6% for grade 4, 16.6% for grade 5, respectively and there was negatively significant correlation between success rate and grade of VUR (P<.01). Degree of improvement of VUR by endoscopic $Deflux^{(R)}$ submucosal injection was not related to age at diagnosis, time to operation, existence of voiding dysfunction or constipation and infused amount of $Deflux^{(R)}$. However, group with anticholinergics medication had significantly lower success rate than non-medication group (P<0.047). Conclusion : Endoscopic $Deflux^{(R)}$ submucosal injection is effective therapy in patient with primary VUR, especially low grade VUR. It can be not only a useful substitute for prophylaxis with antibiotics, but also an effective management prior to ureteroneocystostomy in children with primary VUR.

• The Korean Journal of Nuclear Medicine
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• v.35 no.3
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• pp.192-197
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• 2001

Purpose: Urinary cytology and cystoscopic exam are effective methods for diagnosis of transitional cell carcinoma(TCC). But the former shows drawbacks such as the need for a well-trained examiner, and wide imprecision related to the variability of microscopic exam; the latter is an invasive method. $UBC^{TM}$ test detects the epitope on specific cytokeratin fragments released from epithelium of bladder cancer by immunoradiometric assay. We compared $UBC^{TM}$ test with urinary cytology for diagnosis of TCC to evaluate the utility of $UBC^{TM}$ test. Materials and Methods: Eighty-four patients with hematuria were included in our study. $UBC^{TM}$ tests (IDL Biotech, Sweden) were assayed in mid-stream urine according to the ordinary assay protocol. Nineteen patients were confirmed as TCC by cystoscopic examination and underwent transurethral resection (Group A). Other patients had various benign urinary tract conditions (Group B). Samples were considered positive as the $UBC^{TM}$ concentration was greater than $12{\mu}g/L$. Results: $UBC^{TM}$ levels were significantly different between group A ($95.9{\pm}166.4\;{\mu}g/L$) and group B ($19.2{\pm}85.6{\mu}g/L$) (P<0.001). Sensitivity for diagnosis of TCC was 89.5% (17/19) in UBC test and 47.4% (9/19) in cytology (p<0.05). Specificity for diagnosis of TCC was 81.5% (53/65) in $UBC^{TM}$ test and 100% (65/65) in cytology. $UBC^{TM}$ test was significantly more sensitive in stage Ta, $T_1$ tumors (84.6 vs 38.5%, p<0.05) and in grade I (83.3% vs 16.7%, p<0.05) than cytology. $UBC^{TM}$ test showed a tendency to be more sensitive as the grade was higher (83.3% in Grade I, 90% in Grade II and 100% in Grade III). Conclusion: $UBC^{TM}$ test could be a useful method in distinguishing TCC from other benign genitourinary diseases. Moreover, $UBC^{TM}$ test could be an especially valuable marker for diagnosis of TCC in patients with early TCC of low grade TCC compared to urinary cytology. Therefore, mbined use of $UBC^{TM}$ test in association with cytology is helpful to overcome the limited sensitivity of cytology.

• The Korean Journal of Elementary Counseling
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• v.9 no.1
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• pp.1-20
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• 2010

This research was carried out to see that to what extent KSD reaction can be related to types of sociometric status, and it was carried out on the basis of an hypothesis that KSD reactions of elementary school students in high grades(4th, 5th, 6th grades) would vary according to gender and 5 types of sociometric status, For that purpose, sociometry which were developed by Ahn Iehwan(2007) and KSD, were implemented with students of 20 classes (5 classes of 4th grade, 5 classes of 5th grade and 10 classes of 6th grade) at an elementary school in A city. Number of students surveyed was 366 and it was not exactly the stratified cluster sampling method. To verify 3 hypotheses, independent samples t-test, one way ANOVA, discriminant analysis were made. As a result, there was statistically significant difference in action factor and characteristics factor among 3 factors of KSD reaction by gender, but there was not statistically significant difference in dynamics factor. The result of one way ANOVA showed there was statistically significant difference in characteristics factor and dynamics factor among female students, but there was not statistically significant difference in action factor. Therefore, it was understood that characteristics factor of KSD reaction was closely related to gender difference and types of sociometric status. From the result of this research, it was considered necessary to review KSD scoring system suggested by 田中志帆(2009). And lastly, it was observed that KSD reaction was not effective in evaluating sociometry, and a new approach to the projective drawing test was suggested as a supplementary method for sociometry.

• Journal of Korea Water Resources Association
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• v.35 no.5
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• pp.525-539
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• 2002

Effects of Yongdam Dam discharge conditions on water quality of the Keum River and Daechung Lake inflow were analyzed for various scenarios using WASP5 water quality model. Three different groups of scenarios were tested: 1) Two different weather conditions; the lowest flow year and the highest flow year since the beginning of Daechung Dam operation in 1981, 2) Fine discharge flow rates; 5.4, 8.9, 12.4, 16.4 ㎥/s and field observed flow during the study period, 3) Three conditions of discharge water quality; first grade, second grade by Korean water quality standard and field observed water quality. Effect of changes in Yongdam Dam discharges was greater for dry year. The increase of discharge from the Yongdam Dam will improve water quality of downstream areas only when the water quality of the discharge is equal or better than that of downstream areas. Field observed water qualify data show that BOD concentrations are lower than first grade level but TN and TP concentrations are exceeding 5th and 3rd grade level in Korean standard, respectively. Considering that nutrient control methods in watershed areas of Yongdam dam are limited, it is expected that nutrient concentrations from Yongdam Dam discharge will be higher than 2nd grade water quality standard level. Therefore, it would be important to develop practical management strategies in the watershed area of Yongdam Dam based on field conditions for conservation of water quality in downstream areas.

• Radiation Oncology Journal
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• v.38 no.2
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• pp.119-128
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• 2020

Purpose: Colorectal cancer is becoming an increasing concern in the middle-aged population of Iran. This study aimed to compare the preliminary results of short-course and long-course neoadjuvant chemoradiotherapy treatment for rectal cancer patients. Materials and Methods: In this clinical trial we recruited patients with rectal adenocarcinoma located from 5 cm to 15 cm above the anal verge. Patients in group I (short-course) received three-dimensional conformational radiotherapy with a dose of 25 Gy/5 fractions in 1 week plus concurrent XELOX regimen (capecitabine 625 mg/㎡ from day 1-5 twice daily and oxaliplatin 50 mg/㎡ on day 1 once daily). Patients in group II (long-course) received a total dose of 50-50.4 Gy/25-28 fractions for 5 to 5.5 weeks plus capecitabine 825 mg/㎡ twice daily. Both groups underwent consolidation chemotherapy followed by delayed surgery at least 8 weeks after radiotherapy completion. The pathological response was assessed with tumor regression grade. Results: In this preliminary report on complications and pathological response, 66 patients were randomized into two study groups. Mean duration of radiotherapy in the group II (long-course) was 5 ± 1 days (range, 5 to 8 days) and 38 ± 6 days (range, 30 to 58 days). The median follow-up was 18 months. Pathological complete response was achieved in 32.3% and 23.1% of patients in the shortcourse and long-course groups, respectively (p = 0.558). Overall, acute grade 3 or higher treatment-related toxicities occurred in 24.2% and 22.2% of patients in group I and II, respectively (p = 0.551). No acute grade 4 or 5 adverse events were observed in either group except one grade 4 hematologic toxicity that was seen in group II. Within one month of surgery, no significant difference was seen regarding grade ≥3 postoperative complications (p = 0.333). Conclusion: For patients with rectal cancer located at least 5 cm above the anal verge, short-course radiotherapy with concurrent and consolidation chemotherapy and delayed surgery is not different in terms of acute toxicity, postoperative morbidity, complete resection, and pathological response compared to long-course chemoradiotherapy.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.15 no.5
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• pp.19-29
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• 2012

The purpose of this study is to suggest improvements of Eco-Natural map preparation guideline by presenting assessment methods that can be applied to the result of river ecosystem health survey and assessment, using the Geographic Information System. The area for studying is the main stream of the Hwang River where is easy to collect data and available to compare before and after of river assessment. It was reevaluated by reflecting the result of river ecosystem health assessment of the Ministry of Environment. As the result, Eco-Natural map of the study area reflecting the river assessment, the changes in the area ratio by grade have been increased from 1.14% to 14.03% in the first-grade and from 24.64% to 43.91% in the second-grade. It is considered to present more realistic grade due to the assessment of the rivers that have not been reflected in the meantime. Consequently, the result of this study will be useful for establishing the development projects on the rivers, providing the foundation for more realistic and active protection.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2411-2414
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• 2016

Purpose: To determine the incidence of high-grade cervical intraepithelial neoplasia (CIN2-3) among patients with atypical squamous cells of undetermined significance (ASC-US) Papanicolaou (Pap) smears. Materials and Methods: One-hundred and eighty-seven patients with ASC-US Pap smears who underwent colposcopy with histological study were enrolled between September 2007 and August 2015. Patient factors (including age, parity, current pills used, HIV status, age at first sexual intercourse and number of sexual partners) were obtained. Logistic regression analysis was used to evaluate clinical factors associated with CIN2-3. Results: CIN was diagnosed in 92 of 187 women (49.2%). Sixty-one of these (32.6%) had CIN1 and 31 (16.6%) had CIN2-3. There was no woman who had invasive cancer. There was no correlation of high-grade CIN with factors in this study including age, parity, current pills used, HIV status, age at first sexual intercourse and number of sexual partners. Conclusions: Data from this study showed no invasive cervical cancer was found in patients with ASC-US. There was no patient factor associated with high grade intraepithelial neoplasia in patients with ASC-US Pap smears.

• Journal of the Korean Society of School Health
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• v.16 no.2
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• pp.85-95
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• 2003

This paper surveys and researches primary school students' situation of their school life. The purpose of this paper is to propose the basic information of the accident prevention teaching and the safety management in order to avoid accidents to occur beforehand. We selected m primary students out of the six primary schools in Taebaek City at which the nursing students of Kangwon Tourism College practiced school health. We used SPSS Win for analyzing data. We carne up with the general characteristics and percentage using frequency analysis, mean and standard deviation of each item, the mean difference using T-Test, and the different factors using one-way analysis. The results are as follows: 1. The 6th grade students don't practice safety procedures than the 5th grade students during outside the school. The older the student is, the less it practices safety procedures. 2. Boys practice safety procedures better than the girls during inside and outside the school. 3. Hot -tempered students don't practice safety procedures properly. 4. Most of the students who often use the health room of the school have high scores in safety procedures test and as a result, these students practice safety procedures thoroughly. 5. The grade of safety living activity is the highest during gymnastic class. Next is when the students use the stairs when they are going up and clown. Then, the use of science room In the playground is the lowest grade of safety for living activity.

• The Journal of the Korean bone and joint tumor society
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• v.1 no.2
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• pp.181-188
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• 1995

Malignant tumor of the pelvic bone has nonspecific symptom and it is not easily detected by physical examination or by radiologic study in early stage, because of its anatomical characteristics. Associated with their variety of disease entity, the treatment of malignant pelvic bone tumor is a problematic point. We have analysed 36 cases of malignant pelvic bone tumors diagnosed at the Severance hospital from 1968 to 1993 to provide a reference for diagnosis and treatment of the malignant pelvic bone tumors. We found that the chondrosarcoma(27.8%) and the osteogenic sarcoma(27.8%) were the most common type of pelvic bone malignancy, and then, in the order of incidence, there were Ewing's sarcoma(16.7%), malignant fibrous histiocytoma(11.1%). There were differences of the age distribution among each diseases and the average age was Ewing's sarcoma 20.5, osteogenic sarcoma 27.2, chondrosarcoma 40.0, malignant fibrous histiocytoma 64.8, respectively. Three of the 5 patients with low grade tumors survived(60%), whereas 3 of the 17 patients with high grade tumors survived(18%). The survival rate of the low grade malignant group was 60%, the high grade was 18%.

• Journal of Power System Engineering
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• v.19 no.5
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• pp.45-51
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• 2015

Grade 91 steel is used for the major structural components of Generation-IV reactor systems such as a very high temperature reactor (VHTR) and sodium-cooled fast reactor (SFR). Since these structures are designed for up to 60 years at elevated temperatures, the prediction of long-term creep life is very important to determine an allowable design stress of elevated temperature structural component. In this study, a large body of creep rupture data was collected through world-wide literature surveys, and using these data, the long-term creep life was predicted in terms of three methods: Larson-Miller (L-M), Manson-Haferd (M-H) and Wilshire methods. The results for each method was compared using the standard deviation of error. The L-M method was overestimated in the longer time of a low stress. The Wilshire method was superior agreement in the long-term life prediction to the L-M and M-H methods.