• Title/Summary/Keyword: Gm2S-1

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Correlation of Testosterone and Pain Threshold in the Patients with Somatoform Disorder (신체형 장애에서의 Testosterone과 통각 역치의 상관관계)

  • Park, Jae-Hong;Kim, Myung-Jung;Park, Je-Min;Kim, Yong-Ki;Han, Kwi-Won;Park, Seong-Hwa;Yun, Kyung-Il;Chung, Young-In;Kim, Sung-Gon
    • Korean Journal of Psychosomatic Medicine
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    • v.6 no.1
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    • pp.22-27
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    • 1998
  • Thirteen female patients of somatization disorder, undifferentiated somatoform disorder and somatoform disorder, NOS, diagnosed by DSM-IV were studied for their pain threshold and serum testosterone and the results were compared with the respective data of 20 control females. The results are as follows : 1) The pain threshold as measured by Variable Weight Pressure Algometer was significantly lower in the patient group(153.8${\pm}$39.5 gm/$0.05mm^2$) as compared to the control group(197.5${\pm}$66.7 gm/$0.05mm^2$)(p<0.05). 2) There was no significant difference of serum testosterone between the patient(0.175${\pm}$0.081 ng/ml) and the control(0.174${\pm}$0.108 ng/ml) groups. 3) A significant positive correlation was noted between the pain threshold and serum testosterone in the patient group(r=0.632, p<0.05, two tailed, Pearson's correlation test), but not in the normal control group(r= -0.405). From these results, it was suggested that the role of testosterone in endogenous pain control system might be more important in somatoform disorders than normals.

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Changes in Water and Electrolyte Distribution and Blood Glucose Concentration following Irreversible Hemorrhagic Shock (비가역성 실혈성 쇽에서 본 가토심근, 혈장의 전해질 및 혈당량 변화)

  • Kim, Ki-Whan;Nam, Kee-Yong
    • The Korean Journal of Physiology
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    • v.2 no.1
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    • pp.47-52
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    • 1968
  • Twenty white rabbits anesthetized with nembutal (30 mg/kg) were employed in this experiment. Five of them served as controls; the remaining rabbits as experimental group were subjected to irreversible hemorrhagic shock. Shock was induced by bleeding the animals until mean blood pressure decreased to a level of 50-40 mmHg. This level of pressure was maintained for 3-4 hours, after which the drawn blood was reinfused. The reinfusion of blood caused the elevation of arterial pressure almost the control level for some minutes, after which a gradual and progressive decline of blood pressure became evident. This decline was thought to be the result from irreversible hemorrhagic shock. When mean blood pressure declined to less than 50 mmHg, chest was opened and samples of arterial blood and left ventricular muscle were taken. Left ventricular muscle and blood plasma were analyzed for potassium, sodium, chloride and water content. Blood glucose concentration was determined by Somogyi-Nelson's method. Extracellular and intracellular myocardial water and electrolyte content were calculated on the basis that electrolytes are distributed between plasma water and interstitial water according to Gibbs-Donnan equilibrium. In this calculation extracellular water was substituted for Na space. The findings obtained were as follows: 1. The concentration of blood glucose was 87mg% in the controls and it rose to 222 mg% in shock (P<0.01). 2. Plasma potassium elevated significantly from 3.3 mEq/l in controls to 8.0 mEq/l in shock (P<0.01), while small decreases in sodium (151-146 mEq/l) and chloride (102-96 mEq/l) were observed (P<0.3, P<0.1), 3. The changes of blood water content (83.1-84.3%) and cardiac water content (77.5-78.3 gm/100gm WT) were observed. 4. In control animals myocardial potassium levels which averaged 30.2 mEq/100 gmDT rose significantly to 40.3 mEq/100 gmDT in shock (P<0.01), while moderate decreases in sodium(16.3-14.3 mEq/100 gmDT) were observed in shock. 5. The calculated transmembrane resting potential of left ventricular muscle of control animals averaged 95 mV, while rabbits in shock averaged 77 mV. (P <0.01). The findings of this experiment do not correspond with the conclusions that myocardial depression seems to be the cause of irreversible hemorrhagic shock, because the excitability of heart muscle is elevated. From the point of view that the lowered transmembrane resting potential, the cause of death in terminal stage of irreversible hemorrhagic shock may be ventricular fibrillation. It can't be said, however, that the lowered transmembrane resting potential is responsible for the transition from reversible to irreversible hemorrhagic shock. The marked increase in blood glucose suggested that glycogenolysis in the liver is favorably active in shock.

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Characterization and Evaluation of Worker s Exposure to Airborne Glass Fibers in Glass Wool Manufacturing Industry (유리섬유 단열재 제조업 근로자의 공기중 유리섬유 폭로 특성 및 평가 방법에 관한 연구)

  • 신용철;이광용;박천재;이나루;정동인;오세민
    • Journal of Environmental Health Sciences
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    • v.22 no.2
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    • pp.43-57
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    • 1996
  • To characterize worker's exposure to glass fibers, to find the correlation between airborne total dust concentrations and fiber concentrations and to recommend an appropriate evaluation method for worker's exposure to fibrous dusts in glass wool industry, we carried out this study. Average respirable fiber levels at five factories were 0.013-0.056 f/cc, and fairly below the OSHA PEL, 1 f/cc. A factory showed the lowest airborne fiber level, 0.013 f/cc, which was different significantly from those of other factories of which average fiber concentration was 0.046 f/cc. The cutting and grinding operations of insulation products resulted in higher airborne fiber cocentrations than any other processes(p<0.05). To characterize airborne fiber dimension, fiber length and diamter were determined using phase contrast microscope. The geometric means of airborne fiber lengths were $42-105 \mu m$. One factory had airborne fibers whose length distribution(GM = $105 \mu m$) was different from those of other factories(GM = $42-50 \mu m$). The percentages of respirable fibers less thinner than 3 gm were 38.9-90.9% at four factories, and two factories of them had the higher percentages than others. The findings explain for variation of airborne fiber diameters between factories. On the other hand, between the processes were the difference of fiber-length distributions observed. The cutting and grinding operations showed shorter fiber-length distributions than the fiber forming one. However, fiber-diameter distributions or respirable fiber contents were similar in all processes. The airborne fiber concentrations and the dust concentrations had relatively weak correlation(r=0.25), thus number of fibers couldn't be expected reliably from dust amount. Fiber count is appropriate for assessing accurate exposures and health effects caused by fibrous dusts including glass fibers. Ministry of Labor have established occupational exposure limit to glass fibers as nuisiance dust, but should establish it on the basis of respirable fiber concentration to provide adequate protection for worker's health

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Low voltage Low power OTAs using bulk driven in 0.35㎛ CMOS Process (0.35㎛ CMOS 공정에서 벌크 입력을 사용한 저전압 저전력 OTAs)

  • Kang, Seong-Ki;Jung, Min-Kyun;Han, Dae-Deok;Yang, Min-Jae;Yoon, Eun-Jung;Yu, Chong-Gun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.10a
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    • pp.451-454
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    • 2015
  • This paper introduces 3 type of OTAs with $0.35-{\mu}m$ standard CMOS technology for Low-Power, Low-Voltage. The first type is a two-stage OTA designed to operate with a 1-V VDD and it has $1.774{\mu}W$ low power consumption. All transistors are operating in strong inversion. It takes Gm-Enhancement techniques to compensate gm, which is lowered by Bulk-Driven technique and has an Wide swing current mirror for low voltage operation and a Class-A output. The second type is a Two-stage OTA designed to operate with a 0.8-V VDD and It has 52nW low power consumption and 112dB high gain. The current mirror uses Composite Transistor binding Gates of two MOSFET to raise Rout which is similar with cascode structure. The third type is a Two-stage OTA designed to operate with a 0.6-V VDD and It has 160nW low power consumption and 72dB high gain. It takes Level Shift technique by Common Gate structure to amplify signals without additional bias voltage at second stage.

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Bacteriological and Physiochemical Quality of Seawater and Surface Sediments in Sacheon Bay (사천만의 해수 및 표층 퇴적물의 세균학적 및 이화학적 특성)

  • Park, Jun-Yong;Kim, Yeong-In;Bae, Ki-Sung;Oh, Kwang-Soo;Choi, Jong-Duck
    • Journal of agriculture & life science
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    • v.44 no.2
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    • pp.7-15
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    • 2010
  • This study was conducted to investigate the bacteriological and physiological quality of seawater and surface sediments in Sacheon Bay of Korea from January to September in 2009. During the study period, the means of temperature was range from 5.3 to $24.9^{\circ}C$ (mean $17.7{\pm}0.4^{\circ}C$), transparency range from 1.4 to 2.5 m (mean $1.8{\pm}0.5m$), suspended solid ranged from 16.2 to 35.8 mg/L (mean $24.2{\pm}2.2mg/L$), chemical oxygen demand ranged from 1.42 to $3.29mgO_2/L$ (mean $2.06{\pm}0.55mgO_2/L$), dissolved oxygen ranged from 6.7 to 9.5mg/L (mean $7.9{\pm}0.6mg/L$), respectively. Seafood, if eaten raw, carries the risk of food poisoning. Seafood poisoning is often cause by pathogenic microorganism originating from fecal contamination, such as Salmonella sp., Shigella sp. and norovirus. Fecal coliforms are an important indicator of fecal contamination. Therefor, data on fecal coliform are very important for evaluating the safety of fisheries in coastal areas. So, we investigated the sanitary indicate bacteria. In this study, 56 sea water samples were collected from the Sacheon Bay, and total and fecal coliforms were compared and analyzed. The coliform group and fecal coliform MPN's of sea water in Sacehon Bay were ranged from <1.8~7,900 MPN/100mL (GM 214.7 MPN/100mL) and <1.8~330 MPN/100mL (GM 9.7 MPN/ 100mL), respectively. Total coliforms were detected in 75.0% of the samples and 76.2% of the total coliforms were fecal coliforms. During the study period, the means of water content, ignition loss, COD, and acid volatile sulfates in sediments in Sacheon Bay were $53.28{\pm}2.58%$, $9.38{\pm}0.42%$, $14.23{\pm}3.36mgO_2/g$, $0.09{\pm}0.07mgS/g$, respectively.

Application of Quadratic Algebraic Curve for 2D Collision-Free Path Planning and Path Space Construction

  • Namgung, Ihn
    • International Journal of Control, Automation, and Systems
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    • v.2 no.1
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    • pp.107-117
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    • 2004
  • A new algorithm for planning a collision-free path based on an algebraic curve as well as the concept of path space is developed. Robot path planning has so far been concerned with generating a single collision-free path connecting two specified points in a given robot workspace with appropriate constraints. In this paper, a novel concept of path space (PS) is introduced. A PS is a set of points that represent a connection between two points in Euclidean metric space. A geometry mapping (GM) for the systematic construction of path space is also developed. A GM based on the 2$^{nd}$ order base curve, specifically Bezier curve of order two is investigated for the construction of PS and for collision-free path planning. The Bezier curve of order two consists of three vertices that are the start, S, the goal, G, and the middle vertex. The middle vertex is used to control the shape of the curve, and the origin of the local coordinate (p, $\theta$) is set at the centre of S and G. The extreme locus of the base curve should cover the entire area of actual workspace (AWS). The area defined by the extreme locus of the path is defined as quadratic workspace (QWS). The interference of the path with obstacles creates images in the PS. The clear areas of the PS that are not mapped by obstacle images identify collision-free paths. Hence, the PS approach converts path planning in Euclidean space into a point selection problem in path space. This also makes it possible to impose additional constraints such as determining the shortest path or the safest path in the search of the collision-free path. The QWS GM algorithm is implemented on various computer systems. Simulations are carried out to measure performance of the algorithm and show the execution time in the range of 0.0008 ~ 0.0014 sec.

Bioassay on PSP in Some Shellfishes from Pusan and Kyungnam Area (부산·경남 지역의 일부 패류에 함유된 마비성 패독에 관한 연구)

  • Chun, J.H.;Lee, J.T.;Kim, S.C.;Lee, C.U.;Kim, J.Y.;Kim, B.S.;Paik, N.W.
    • The Korean Journal of Malacology
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    • v.2 no.1
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    • pp.1-9
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    • 1986
  • The authors carried out paralytic shellfish poison bioassay on the 9 kinds of shellfishes collected from Pusan and Kyungnam areas of Korea from April to July, 1986. The areas are the main producing district of fisheries in Korea and the samples were collected from their producing sites-natural, cultured and marketed. There were little or no PSP in the majority of the shellfishes, but 3 natural (Pusan Il-Kwang $700{\mu}g$, Koje Okpo $648{\mu}g$, Chungmoo Madong $124{\mu}g/100gm$ meat) and 1 marketed (Pusan Chakalchi $490{\mu}g/100gm$ meat) blue mussels contained relatively high PSP only in April. It is considered that there will be a possibility of paralytic shellfish poisoning, and control program for preventing the poisoning is necessary in Korea.

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Accumulation and Inhibitory Effects of Microcystin on the Growth of Rice and Broccoli

  • Maejima, Kazuhiko;Muraoka, Terukazu;Park, Ho-Dong
    • Korean Journal of Ecology and Environment
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    • v.47 no.spc
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    • pp.19-30
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    • 2014
  • Microcystins (MCs) produced by cyanobacteria are severe hepatotoxins for mammalian and protein phosphatase inhibitors. Irrigation water for grain and vegetables is often contaminated with cyanobacteria and microcystin during warm seasons. We assessed the effects of various concentrations (0, 0.01 to $10{\mu}gmL^{-1}$) of microcystin-LR (MC-LR) and microcystin-RR (MC-RR) exposure on Oryza sativa (rice) and Brassica oleraces var. italica (broccoli). The $EC_{50}$ of leaves and roots of rice was 0.9 and $1.1{\mu}gMC-LRmL^{-1}$, respectively. The no observed effect level (NOEL) of rice was less than $0.1{\mu}gmL^{-1}$ ($100{\mu}gL^{-1}$). The $EC_{50}$ of the stems and roots of broccoli was 8.7 and $7.2{\mu}gMC-RRmL^{-1}$, respectively. There was no difference in the germination rate of broccoli among microcystin-RR concentrations. After exposure to 0, 0.01 to $10{\mu}gmL^{-1}$ MC-RR for seven days, 14, 89 and 154 ng mg-1 (dry weight) MC-RR accumulated in B. oleracea. These $EC_{50}$ values showed that microcystin-LR and -RR affected the growth of rice and broccoli. These findings suggest that MC is carried into terrestrial ecosystems via irrigation, and that the biota of higher ecological niches can be influenced by MC through bioaccumulation. Therefore, a guideline for MC concentrations in irrigation water should be set using the NOEL.

Spectrophotometric Determination of Iron with 2-Hydroxybenzaldehyde-5-nitro-pyridylhydrazone after Separation with Amberlite XAD-7 Nonionic Resin (Amberlite XAD-7 비이온성 수지로 분리 후 2-Hydroxybenzaldehyde-5-nitro-pyridylhydrazone을 이용한 철의 분광학적 정량)

  • Park, Chan Il;Chung, Byung Doo;Jung, Duck Chae;Cha, Ki Won
    • Journal of the Korean Chemical Society
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    • v.43 no.5
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    • pp.522-526
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    • 1999
  • 2-Hydroxybenzaldehyde-5-nitro-pyridylhydrazone (2HB-5NPH) was synthesized and its application to the spectrophotometric determination of iron was studied. The reagent reacts with iron in the pH range 6.0-7.5 to form a yellow coIored 1:2 chelate which is very stable in methanol solution. Beer's law is obeyed in the concentration range 0.05∼2.0 ${\mu}gmL^{-1}$ iron and separation procedure using a short column filled with Amberlite XAD-7 nonionic chelating resin is proposed for the spectrophotometric determination of traces of iron. The influence of several ions as interference was discussed. The separation of Fe(III) ion from the mix-ture solution were carried out with the buffer solution (pH 5.0) and 0.25M HCl as eluents.

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World agricultural crop supplies and Korea's food security (세계 농산물 수급과 형질전환작물에 대한 우리나라 정책 방향)

  • Chung, Chang-Ho;Kyung, Kyu-Hang
    • Journal of Plant Biotechnology
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    • v.36 no.4
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    • pp.301-308
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    • 2009
  • Higher agricultural commodity prices are a particular concern for food importing countries like Korea that has a very low self-sufficiency ratio. Korean people eat approximately 4.5 million metric tons of rice each year, which is met without a problem by domestic production. The domestic production of corn and soybean which are important raw materials for commercial food processing and livestock feed is only minimal. Demands of corn and soybean in Korea are approximately 7.2 million and 1.3 million metric tons per year, respectively. Since Korean consumers are reluctant to accept biotech (GM) foods, Korean food processors are fighting an up-hill battle in purchasing non-biotech (non- GM) crops which are becoming scarce.