• Applied Microscopy
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• v.21 no.1
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• pp.1-20
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• 1991

The effects of exogenous $Ca^{2+}$ stimulation on the post-ischemic myocardial cells were studied using isolated Langendorff-perfused guinea pig hearts. At the starting point of reperfusion, Tyrode solutions, each containing 2.0mM, 4.0mM and 8.0mM $CaCl_2$ respectively, were administered for 2 minutes apart by descending, ascending, or by combined sequences followed by standard Tyrode solution containing 1.0mM $CaCl_2$. The minutes of global ischemia produced reversible but moderate to severe degree of myocardial ultrastructrual changes including focal destruction of sarcolemma, loss of nuclear matrix, clumping and margination of chromatins, mitochondrial swelling, destruction of mitochondrial cristae, shortening of sarcomeres, focal loss of myofibrils, and separation of cell junctions. In spite of reperfusion, the ultrastructure was more severely damaged and irreversible changes such as intracellular fluid accumulation, contracted sarcomeres, mitochondrial destruction, disruption of sarcolemma, loss of nuclear matrix, and separation of cell junction were observed in a large number of cells. In contrast, Tyrode-perfused $Ca^{2+}$-stimulated myocardial cells showed relatively well preserved ultrastucture, except slight changes including focal mitochondrial swelling, widening of T-tubule, and widening of cell junctions, especially at fasciae adherentes. The post-ischemic $Ca^{2+}$-stimulated reperfused myocardial cells produced focal changes such as mitochondrial destruction, disintegration of sarcolemma, widening of T-tubule, and intracellular fluid accumulation with slight variation in degree of changes by the method of $Ca^{2+}$ administration sequence. However, in a large number of the myocardial cells, chromatins were redistributed relatively evenly in the nuclear matrix, mitochondrial cristae were tightly packed, and a considerable number of intramitochondrial granules and glycogen granules reap-pealed. These results indicate that exogenous $Ca^{2+}$ stimulation in the initial period of reperfusion may be beneficial to salvage or to reduce the post-ischemic myocardium from further deleterious changes, and that the beneficial effects may be derived from the reserves of the function of the intracellular $Ca^{2+}$ regulating organelles and/or from the responsiveness of contractile apparatus to $Ca^{2+}$ stimulation.

• Journal of the Society of Naval Architects of Korea
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• v.28 no.1
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• pp.150-168
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• 1991

A practical procedure for the ultimate compressive strength-based safety and reliability assessment of the double skin upper deck structure is described. The external compressive stress acting on the upper deck structure which is due to the still water and wave-induced sagging moment is approximately estimated by using the existing rule of classification society. The ultimate compressive stress of double skin structure under the action of sagging moment is analyzed by using idealized structural unit method. Here an idealized plate element subjected to uniaxial load is formulated by idealizing the nonlinear behaviour of the actual element taking account of the initial imperfections in the form of initial deflection and welding residual stress. The interaction effect between the local and global failure in the structure is also taken into consideration. The accuracy of the present method is verified comparing with the present solution and the existing numerical and experimental results for unit member and welded box columns. The safety of the structure is evaluated using the concept of conventional central safety factor and the reliability assessment is made by using Cornel's MVFOSM method. The present procedure is then applied to upper deck structure of double skin product oil carrier. The influence of the initial imperfections and the yield stress of the material on the safety and reliability of the structure is investigated.

• Journal of the Korean Chemical Society
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• v.60 no.3
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• pp.187-193
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• 2016

In this study, preparation of positively and negatively charged carbon nanotube (CNT)-collagen (CG) hydrogels with pH sensitive characteristic was reported. The positive and negative characteristics of the prepared hydrogels were created by introduction of positively functionalized CNT-NH₂ and negatively functionalized CNT-COOH, respectively, into the collagen hydrogel. The surface charge of CNTs (CNT-NH₂ and CNT-COOH), CG and CNTs/CG hydrogels was measured by Zetasizer. The swelling ratios of CNT-NH₂/CG and CNT-COOH/CG hydrogels in aqueous solution were checked by measuring of weight changes of the hydrogels in the range of pH 2~10. In detail, the positively charged CNT-NH₂/CG hydrogel swelled up to 5% at pH 4 in comparison to the weight at pH 7, while the negatively charged CNT-COOH/CG hydrogel swelled up to 10% at pH 10. The prepared CNT-NH₂/CG and CNT-COOH/CG hydrogels will be very useful as pH sensitive oral drug-delivering systems for gastrointestine (pH ~2) and small intestine (pH ~9), respectively.

• Land and Housing Review
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• v.4 no.4
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• pp.383-393
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• 2013

The trends of green growth and eco-friendliness came to be the core development indicator for the sustainable global environment. Korean government reflected these trends in the main flows of the national development index, and suggested diverse directions for green construction technologies and high quality construction environment through Third master plan for construction environment. However, the efforts to follow these trends during the construction process as a step for production phrase are not being considered enough yet. In this study, we identified the basic environmental management factors in order to enhance the eco-friendliness of public housing construction sites, and suggested the reasonable conducting parties and process for those respective factors. The results of this study are expected to be the valuable reference in defining the required activities and participants' responsibilities, and improving the work process for systematic on-site environmental management. In applying those results, the discussion should be followed on the executing party of each unit activity and the responsibility assignment for each process. At the same time, the legislation and standard related to environment need to be essentially amended. In the future, the method of evaluating the environmental management activities, and the technical solution to environmental problems are to be reviewed as a further research for successful environmental management.

• Journal of the Korean Society of Combustion
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• v.20 no.4
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• pp.34-41
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• 2015

Oxy-methane nonpremixed flames diluted with $CO_2$ were investigated to clarify impact of radiation heat loss and chemical effects of additional $CO_2$ to oxidizer stream on flame extinction. Flame stability maps were presented with functional dependencies of critical diluents mole fraction upon global strain rate at several oxidizer stream temperatures in $CH_4-O_2/N_2$, $CH_4-O_2/CO_2$, and $CH_4-O_2/CO_2/N_2$ counterflow flames. The effects of radiation heat loss on the critical diluent mole fractions for flame extinction are not significant even at low strain rate in nonpremixed $CH_4-O_2/N_2$ diffusion flame, whereas those are significant at low strain rate and are negligible at high strain rate (> $200s^{-1}$) in $CH_4-O_2/CO_2$ and $CH_4-O_2/CO_2/N_2$ counterflow flames. Chemical effects of additional $CO_2$ to oxidizer stream on the flame extinction curves were appreciable in both $CH_4-O_2/CO_2$ and $CH_4-O_2/CO_2/N_2$ flames. A scaling analysis based on asymptotic solution of stretched flame extinction was applied. A specific radical index, which could reflect the OH population in main reaction zone via controlling the mixture composition in the oxidizer stream, was identified to quantify the chemical kinetic contribution to flame extinction. A good correlation of predicted extinction limits to those calculated numerically were obtained via the ratio between radical indices and oxidizer Lewis numbers for the target and baseline flames. This offered an effective approach to estimate extinction strain rate of nonpremixed oxy-methane flames permitting air infiltration when the baseline flame was taken to nonpremixed $CH_4-O_2/N_2$ flame.

• Journal of Distribution Science
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• v.16 no.8
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• pp.63-68
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• 2018

Purpose - Lettuce (Lactuca sativ L.) is one of the economically important vegetable crops, which worldwide market value is over 100 billion U.S. dollar. In Korea, about 89.7 kilo ton of lettuce was produced in 3400ha in 2016, recoded as No. 1 vegetable crop in domestic green house production. However, recently, domestic lettuce production and cultivation areas are all getting decreased. Thus, novel approaches are needed to be implemented to revive the production. Research design, data and methodology - In this review paper, we first prioritized the end-user traits which are imperative to positively stimulate the domestic lettuce market and discussed relevant genomics strategies. Especially, we assessed a possibility whether school meal program would be a potential niche market. Results - The genomics technologies, which become widely applied in the crop biotechnology since 2008 when next generation sequencing method was developed, may be a good solution in the crop improvement, efficiently gathering valuable information of agriculturally useful traits. Significantly, in lettuce, the high quality whole genome sequence, based on Lactuca sativa cv. Salinas, is publically available and this genomics platform, thus, would be implemented in lettuce breeding program to innovate relevant end-user traits both for the farmers and customers, including the disease resistance to the Fusarium wilt, productivity under hot weather conditions, various nutritional qualities and so forth. These improvements will boost domestic lettuce industries in the near future. Conclusions - Due to the nutritional distinctions comparing to the western style lettuces, domestic leaf lettuces could be one of the important vegetables in the school meal programs. To make it happen, we would better devise diverse recipes to make a salad with it, instead of only using as a wrap vegetable. Meanwhile, novel lettuce varieties need to be developed, which are favorable to the students and also easy to be handled with while processing. Overall, to achieve international competence in the lettuce industries, we need to create elite lettuce varieties that satisfies domestic farmers as well as customers, suitable to various niche markets, such as school meal program. Thus, efficient breeding programs using genomics approaches should be established in advance and careful monitoring on the preference of the related customers for a niche market be continued persistently.

• Journal of the Society of Naval Architects of Korea
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• v.39 no.3
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• pp.75-80
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• 2002

In these days of severe struggle for existence, the world has changed a great deal to global and digital oriented period. The enterprises try to introduce new management and production system to adapt such a change. But, if the only new technologies are applied to an enterprise without definite analysis about manufacturing, failure fellows as a logical consequence. Hence, enterprise must analyze manufacturing system definitely and needs new methodologies to mitigate risk. This study suggests that the new approach, which is systems approach for process improvement, is organized to systems analysis, systems diagnosis, and systems verification. Systems analysis analyzes manufacturing systems with object-oriented methodology-UML(Unified Modeling language) from a point of product, process, and resource view. Systems diagnosis identifies the constraints to optimize the system through scientific management or TOC(Theory of constraints). Systems verification shows the solution with virtual manufacturing technique applied to the core problem which emerged from systems diagnosis. This research shows the artifacts to improve the productivity with the above methodology applied to forming shop. UML provides the definite tool for analysis and re-usability to adapt itself to environment easily. The logical tree of TOC represents logical tool to optimize the forming shop. Discrete event simulator-QUEST suggests the tool for making a decision to verify the optimized forming shop.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.36S no.1
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• pp.29-37
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• 1999

In general, the information processing capability of a neural network is determined by its architecture and efficient training patterns. However, there is no systematic method for designing neural network and selecting effective training patterns. Evolutionary Algorithms(EAs) are referred to as the methods of population-based optimization. Therefore, EAs are considered as very efficient methods of optimal system design because they can provide much opportunity for obtaining the global optimal solution. In this paper, we propose a new method for finding the optimal structure of neural networks based on competitive co-evolution, which has two different populations. Each population is called the primary population and the secondary population respectively. The former is composed of the architecture of neural network and the latter is composed of training patterns. These two populations co-evolve competitively each other, that is, the training patterns will evolve to become more difficult for learning of neural networks and the architecture of neural networks will evolve to learn this patterns. This method prevents the system from the limitation of the performance by random design of neural networks and inadequate selection of training patterns. In co-evolutionary method, it is difficult to monitor the progress of co-evolution because the fitness of individuals varies dynamically. So, we also introduce the measurement method. The validity and effectiveness of the proposed method are inspected by applying it to the visual servoing of robot manipulators.

• Korean Chemical Engineering Research
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• v.55 no.2
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• pp.141-155
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• 2017

In the present paper, we investigated the development status of precipitated calcium carbonate (PCC) production using steel slag, which is one of mineral carbonation (MC) technologies, from the standpoint of $CO_2$ utilization. Principle, feature, and global and domestic development status of the mineral carbonation technology were discussed together with the overview of the production method and market of PCC. Mineral carbonation is known as stable and environmentally-friendly technology enabling economical treatment of industrials wastes. Typically, PCC is produced by the reaction of $CO_2$ with supernatant solution after Ca extraction from steel slag followed by the separation of solid and liquid. The development status of MC using steel slag is at the pilot stage (Slag2PCC at Aalto University), and there remains the process economics improvement for commercialization. Key technologies for the further development are efficient extraction of Ca ions from steel slag including impurities removal, valorization of PCC via shape and size control, usage development and value-addition of residual slag, and optimization of reaction conditions for continuous process setup, etc.

• Journal of the Korean Society of Marine Environment & Safety
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• v.20 no.4
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• pp.419-425
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• 2014

The current work investigated the variation of numerical solutions according to the grid number, the distance of the first grid point off the ship surface, turbulence modeling and discretization. The subject vessel is KVLCC. A commercial code, Gridgen V15 and FLUENT were used the generation of the ship hull surface and spatial system and flow computation. The first part of examination, the effect of solutions were accessed depending on the grid number, turbulence modeling and discretization. The second part was focus on the suitable selection of the distance of the first grid point off the ship surface: $Y_P+$. When grid number and discretization were fixed the same value, the friction resistance showed differences within 1 % but the pressure resistance showed big differences 9 % depending on the turbulence modeling. When $Y_P+$ were set 30 and 50 for the same discretization, friction resistance showed almost same results within 1 % according to the turbulence modeling. However, when $Y_P+$ were fixed 100, friction resistance showed more differences of 3 % compared to $Y_P+$ of 30 and 50. Whereas pressure resistance showed big differences of 10 % regardless of turbulence modeling. When turbulence modeling and discretization were set the same value, friction, pressure and total resistance showed almost same result within 0.3 % depending on the grid number. Lastly, When turbulence modeling and discretization were fixed the same value, the friction resistance showed differences within 5~8 % but the pressure resistance showed small differences depending on the $Y_P+$.