• Journal of the Optical Society of Korea
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• v.18 no.2
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• pp.174-179
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• 2014

Since in vitro neural recording and imaging applications based on a surface plasmon resonance (SPR) technique have expanded dramatically in recent years, cytotoxicity assessment to ensure the biosafety and biocompatibility for those applications is crucial. Here, we report the cytotoxicity of the SPR substrate incorporating a flint glass whose refractive index is larger than that of a conventional crown glass. A high refractive index glass substrate is essential in neural signal detection due to the advantages such as high sensitivity and wide dynamic range. From experimental data using primary hippocampal neurons, it is found that a lead-based flint glass is not appropriate as a neural recording template although the neuron cells are not directly attached to the toxic glass. We also demonstrate that the adhesion layer between the glass substrate and the gold film plays an important role in achieving the substrate stability and the cell viability.

• IEMEK Journal of Embedded Systems and Applications
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• v.12 no.1
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• pp.35-41
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• 2017

We propose a face recognition and notification system that can transform visual face information into tactile signals in order to help visually impaired people. The proposed system consists of a glasses type camera, a mobile computer and an electronic cane. The glasses type camera captures the frontal view of the user, and sends this image to mobile computer. The mobile computer starts to search for human's face in the image when obstacles are detected by ultrasonic sensors. In a case that human's face is detected, the mobile computer identifies detected face. At this time, Adaboost and compressive sensing are used as a detector and a classifier, respectively. After the identification procedures of the detected face, the identified face information is sent to controller attached to a cane using a Bluetooth communication. The controller generates motor control signals using Pulse Width Modulation (PWM) according to the recognized face labels. The vibration motor generates vibration patterns to inform the visually impaired person of the face recognition result. The experimental results of face recognition and notification system show that proposed system is helpful for visually impaired people by providing person identification results in front of him/her.

• Restorative Dentistry and Endodontics
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• v.42 no.1
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• pp.48-53
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• 2017

Objectives: The aim of this study was to investigate the ability of the fluorescence-aided caries excavation (FACE) device to detect residual caries by comparing conventional methods in vivo. Materials and Methods: A total of 301 females and 202 males with carious teeth participated in this study. The cavity preparations were done by grade 4 (Group 1, 154 teeth), grade 5 (Group 2, 176 teeth), and postgraduate (Group 3, 173 teeth) students. After caries excavation using a handpiece and hand instruments, the presence of residual caries was evaluated by 2 investigators who were previously calibrated for visual-tactile assessment with and without magnifying glasses and trained in the use of a FACE device. The tooth number, cavity type, and presence or absence of residual caries were recorded. The data were analyzed using the Chi-square test, the Fisher's Exact test, or the McNemar test as appropriate. Kappa statistics was used for calibration. In all tests, the level of significance was set at p = 0.05. Results: Almost half of the cavities prepared were Class II (Class I, 20.9%; Class II, 48.9%; Class III, 20.1%; Class IV, 3.4%; Class V, 6.8%). Higher numbers of cavities left with caries were observed in Groups 1 and 2 than in Group 3 for all examination methods. Significant differences were found between visual inspection with or without magnifying glasses and inspection with a FACE device for all groups (p < 0.001). More residual caries were detected through inspection with a FACE device (46.5%) than through either visual inspection (31.8%) or inspection with a magnifying glass (37.6%). Conclusions: Within the limitations of this study, the FACE device may be an effective method for the detection of residual caries.

• Journal of Broadcast Engineering
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• v.25 no.6
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• pp.973-979
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• 2020

This study aims to objectively and quantitatively determine the social emotion of empathy by collecting pupillary response. 52 subjects (26 men and 26 women) voluntarily participated in the experiment. After the measurement of the reference of 30 seconds, the experiment was divided into the task of imitation and spontaneously self-expression. The two subjects were interacted through facial expressions, and the pupil images were recorded. The pupil data was processed through binarization and circular edge detection algorithm, and outlier detection and removal technique was used to reject eye-blinking. The pupil size according to the empathy was confirmed for statistical significance with test of normality and independent sample t-test. Statistical analysis results, the pupil size was significantly different between empathy (M ± SD = 0.050 ± 1.817)) and non-empathy (M ± SD = 1.659 ± 1.514) condition (t(92) = -4.629, p = 0.000). The rule of empathy according to the pupil size was defined through discriminant analysis, and the rule was verified (Estimation accuracy: 75%) new 12 subjects (6 men and 6 women, mean age ± SD = 22.84 ± 1.57 years). The method proposed in this study is non-contact camera technology and is expected to be utilized in various virtual reality with smart glasses.

• Proceedings of the KIEE Conference
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• 2002.11a
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• pp.60-63
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• 2002

This paper presents bead-based microbiocihps to detect and separate target proteins. Micro beads coated with capture proteins were introduced into a microchamber, and target proteins flowing across the chamber were bound and concentrated. The chip was connected with an external fluid system. Bead surfaces were double-coated with photo-cleavable linkers and capture proteins. The proteins bound on the beads were photo-separated under UV irradiation, and excited to be measured in fluorescence. $38{\sim}50{\mu}m$ sized polystyrene beads were used. SOGs(silicon-on-glass) were used to fabricate the microchip having glasses bonded on both sides. 100 ${\mu}m$ thick silicon channel was formed through silicon deep RIE process. The upper glass cover had holed through to have inlets and outlets fabricated by powder-blastings. In this study, biotin and streptavidin were used as capture proteins and detection proteins, respectively. The protein mixtures of streptavidin, HSA(human serum albumin) and ovalbumin were applied for selective detection test.

• Journal of Sensor Science and Technology
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• v.12 no.3
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• pp.139-148
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• 2003

$LiPO_3$ glass scintillators were fabricated, and lanthanides(except Pm) oxides or chlorides were used as an activator. For the fabrication of $LiPO_3$ glasses, optimum heating conditions were obtained, and the photoluminescence of the glasses was measured by the monochromator. For the best transparency of the glass samples, optimum heating temperature and time are $950^{\circ}C$ and 90 min, respectively. It was found that Pr, Nd, Gd, Ho, Er, Tm, Yb and Lu do not work as activator; emission spectrums of samples with them were equal to those of samples without activators. In the case of samples with Europium, the peaks of emission spectrum of $Eu^{2+}$ and $Eu^{3+}$ were 420 nm and 620 nm respectively. And samples with $Ce^{3+}$ were about 380 nm, and $Tb^{3+}$ were about 550 nm. Glass scintillators with $Be^{3+}$, $Eu^{2+}$, and $Ce^{3+}$ were found to be more applicable to neutron detection. The result of neutron detection by Ra-Be sources showed that $Ce^{3+}$ was found to be the best activator of $LiPO_3$.

• Nuclear Engineering and Technology
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• v.56 no.6
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• pp.2113-2119
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• 2024

This study presents the development and characterization of a prototype TL/OSL reader for the retrospective dose assessment of individuals in radiological emergencies. The reader is portable, semi-automatic, and capable of accurate measurements. The dimension of the reader is 25 × 25 × 37 cm³ and the weight is about 15 kg. The reader consists of a sample moving stage, a heating module, an optical stimulation module, a detection module, a data acquisition (DAQ) unit, a nitrogen gas control module, and a PC with a GUI program. The reader has three measurement modes: TL, CW_OSL, and custom mode. The reader was characterized using commercial thermal luminescence dosimeters (TLD, LiF:Mg,Cu,Si) and optically stimulated dosimeters (OSLD, Al₂O₃:C), as well as fortuitous materials, such as display glasses and resistors of mobile phone. The results showed that the reader is capable of measuring signals with a detection limit of up to 0.02 mGy using a commercial dosimeter. In the dose recovery test using fortuitous materials, the reconstructed doses obtained three days post-irradiation closely aligned with the initially administered doses. As a result, this study suggests that the developed TL/OSL reader is a promising instrument for emergency dose assessment at accident sites.

• The KIPS Transactions:PartB
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• v.9B no.6
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• pp.853-862
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• 2002

Face Detection can be defined as follows : Given a digitalized arbitrary or image sequence, the goal of face detection is to determine whether or not there is any human face in the image, and if present, return its location, direction, size, and so on. This technique is based on many applications such face recognition facial expression, head gesture and so on, and is one of important qualify factors. But face in an given image is considerably difficult because facial expression, pose, facial size, light conditions and so on change the overall appearance of faces, thereby making it difficult to detect them rapidly and exactly. Therefore, this paper proposes fast and exact face detection which overcomes some restrictions by using neural network. The proposed system can be face detection irrelevant to facial expression, background and pose rapidily. For this. face detection is performed by neural network and detection response time is shortened by reducing search region and decreasing calculation time of neural network. Reduced search region is accomplished by using skin color segment and frame difference. And neural network calculation time is decreased by reducing input vector sire of neural network. Principle Component Analysis (PCA) can reduce the dimension of data. Also, pose estimates in extracted facial image and eye region is located. This result enables to us more informations about face. The experiment measured success rate and process time using the Squared Mahalanobis distance. Both of still images and sequence images was experimented and in case of skin color segment, the result shows different success rate whether or not camera setting. Pose estimation experiments was carried out under same conditions and existence or nonexistence glasses shows different result in eye region detection. The experiment results show satisfactory detection rate and process time for real time system.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2007.11a
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• pp.439-442
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• 2007

강인한 얼굴 인식 시스템을 만들기 위해서는 안경의 제거가 중요한 요소이다. 이를 위해서는 뛰어난 성능의 안경 검출 방법이 필수적이다. 본 논문에서는 안경의 유무 판단에 관한 새로운 방법을 제안한다. 영상은 조명 부분과 반사부분의 곱으로 이루어져 있다. 얼굴의 경우 안경 고유의 반사계수와 얼굴 고유의 반사계수가 다른 점에 착안하여 anisotropic smoothing 방법을 이용하여 입력 얼굴 영상에서의 반사 부분을 얻고, 이를 이용하여 안경의 반사 부분을 얼굴의 반사부분에서 검출한 뒤 이진화한다. 이후, 이진화 된 안경 픽셀 수를 이용하여 안경의 유무를 판단한다.

• Biomedical Science Letters
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• v.10 no.2
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• pp.75-84
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• 2004

Massive identification of differentially expressed patterns has been used as a tool to detect genes that are involved in disease related process. We employed circular single stranded sense molecules as probe DNA for a DNA chip. The circular single stranded DNAs derived from 1,152 unigene cDNA clones were purified in a high throughput mode from the culture supernatant of bacterial transformants containing recombinant phagemids and arrayed onto silanized slide glasses. The DNA chip was examined for its utility in detection of differential expression profile by using cDNA hybridization. Hybridization of the single stranded probe DNA were performed with Cy3- or Cy5-labeled target cDNA preparations at $60^\circ$C. Dot scanning performed with the hybridized slide showed 29 up-regulated and 6 down-regulated genes in a cancerous liver tissue when compared to those of adjacent noncancerous liver tissue. These results indicate that the circular single stranded sense molecules can be employed as probe DNA of arrays in order to obtain a precious panel of differentially expressed genes.