• Journal of Chest Surgery
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• 제20권3호
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• pp.582-587
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• 1987

Castleman`s disease, giant lymph node hyperplasia, is a rare benign disease. The lesion usually consists of a single node, unassociated with any abnormality of the adjacent lymph nodes or other organs. In the first accounts of giant lymph node hyperplasia of Castleman, the lesion was described as solitary and localized to the mediastinum, which is still the most frequent site of involvement. The disease occurs in all age groups and there is no particular sex preference. It is symptomless and is usually detected on chest films as an incidental finding. On a single involvement, it does not recur after excision, whether total or partial, and the main indication of operation is to rule out more serious tumors. Recently multicentric form appears to be a variant of classic giant lymph node hyperplasia and is associated with significant morbidity and mortality. Histologically, two distinct types have been reported; hyaline-vascular and plasma cell. The hyaline-vascular type of lesion is much more common than the plasma cell type. We report two cases of the hyaline-vascular type of Castleman`s disease.

• Journal of Korean Neurosurgical Society
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• 제43권3호
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• pp.169-171
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• 2008

Giant lymph node hyperplasia (Castleman's disease) is a nonneoplastic lymphoproliferative disorder of unknown etiology that usually occurs in the chest. Its morphological recognition is based on a composition of various histological features. The mass is often asymptomatic, but it can cause nonspecific thoracic symptoms, such as regional pain. This disease can be found wherever lymph nodes are present, but two-thirds of these tumors are found in the chest, along the tracheobronchial tree in the mediastinum or lung hilus. However, we experienced an unusual case of Castleman's disease as a cause of back pain that was localized in the posterior mediastinum bordering the chest wall.

• Journal of Yeungnam Medical Science
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• 제9권1호
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• pp.175-180
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• 1992

저자들은 multicenteric form의 거대 림프양 증식증 1례를 치험하였기에 그 희귀성에 비추어 문헌 고찰과 함께 보고하는 바이다.

• 대한두경부종양학회지
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• 제32권2호
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• pp.35-39
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• 2016

Castleman's disease (CD) is an uncommon lymphoproliferative disorder. The disease entity is classified into 2 clinical subtypes, unicentric and multicentric type. Prevalence of lymphoid malignancy in multicentric CD (MCD) is very low. In this case, we report a case of 77 years old woman who developed high fever and swelling in both side of her neck. Neck lymph node biopsy revealed plasma cell hyperplasia. Patient's symptom was subsided after treatment with Dexamethasone. Three months later, multiple lymph node enlargement was developed in abdomen and neck area again. Repeated neck lymph node biopsy confirmed diffuse large B cell lymphoma. The patient started chemotherapy.

• Tuberculosis and Respiratory Diseases
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• 제44권3호
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• pp.669-676
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• 1997

Castleman's disease is uncommon lymphoproliferative disorder as giant lymph node hyperplasia and angiofollicular lymph node hyperplasia. Multicentric variant of Castleman's disease, plasma cell type has been described that has more generalized lymph node involvement as well as involvement of other organ systems than localized type. Multicentric plasma cell type is frequently accompanied by systemic manifestations, such as weight loss, lowgrade fever and weakness. But the reported cases of pulmonary parenchymal involvement are rare and have almost consisted of hyalinized granuloma adjacent to a bronchus. We report a patient with Castleman's disease of the lung, pathologically proven interstitial pulmonary involvement.

• 대한두경부종양학회지
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• 제20권2호
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• pp.194-197
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• 2004

Castleman's disease was first described from Benjamin Castleman in 1956. The disease today is enumerated among lymphoproliferative disorders and has unknown etiology. Although the mediastinum is a their most common location, they also occurs in other areas of the body, usually where lymph nodes are normally found. Castleman's disease of the neck is very rare. We describe a case of Castleman's disease of the neck in a middle aged man, and discuss the clinical presentation, radiological findings, and pathological features.

• 대한두개안면성형외과학회지
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• 제18권2호
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• pp.122-127
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• 2017

Castleman's disease (CD) is an uncommon benign lymphoproliferative disorder of unknown etiology. Histopathologically, it is divided into three types: hyaline-vascular, plasma cellular, and multicentric CD. The mass usually presents asymptomatically; however, it can cause non-specific symptoms such as fever and fatigue. Although CD can be found wherever lymph nodes are present, 75% of cases are reported in the mediastinum, and occurrence in the head and neck is rare. Herein, we report a rare case of CD presenting as a superficial mass in the temporal region. To the best of our knowledge, this is the first report of temporal CD in Korea involving a young patient.

• Clinical and Experimental Pediatrics
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• 제52권9호
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• pp.1029-1034
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• 2009

가와사끼병은 주로 소아기에 발생하는 급성 전신 혈관염으로, 원인은 아직 명확히 알려져 있지 않다. EBV는 전염성 단핵구증의 원인으로 잘 알려져 있으며, 또한 가와사키병의 원인으로도 보고된 바 있다. 가와사끼병으로 인한 합병증은 관상동맥류를 포함한 심혈관계 합병증이 주를 이루지만, 다양한 종류의 합병증들이 보고 되고 있다. 저자들은 EBV 감염과 연관된 전염성 단핵구증, 거대 관상동맥류, 심낭삼출, 비경색증이 동반된 난치성 가와사끼병 환자 1예를 경험하였기에 보고하는 바이다. 환자는 3번의 면역글로불린 치료에도 반응이 없었지만, pulse methylprednisolone 치료 후에 임상 증상은 급격히 호전되었고, 거대 관상동맥류만 지금까지 지속되고 있다.