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Effect of Korean Medicine Treatment on Vancomycin-resistant Enterococci Colonization in a Stroke Patient: A Case Report (반코마이신 내성 장알균(Vancomycin Resistant Enterococci)이 검출된 뇌졸중 환자의 집락 해제에 대한 한방치료 1례 : 증례보고)

  • Seo, Hyung-bum;Lee, Chan;Cho, Im-hak;Heo, Gi-yoon;Kang, Hee-kyung;Han, Chang-woo;Kim, So-yeon;Choi, Jun-yong;Park, Seong-ha;Yun, Young-ju;Hong, Jin-woo;Kwon, Jung-nam;Lee, In
    • The Journal of Internal Korean Medicine
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    • v.41 no.6
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    • pp.1191-1199
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    • 2020
  • We studied the effect of Korean medicine treatment on the clearance of vancomycin-resistant enterococcus (VRE) colonization and on improvement in symptoms in a stroke patient. The patient was continuously followed up with stool VRE cultures while being treated with herbal medicine, Chunglijagam-tang, acupuncture, and oxygen therapy. We also checked the coccygeal pressure sore condition and the oxygen levels during therapy. No VRE colonization was found after treatment and the oxygen levels and pressure sores had improved. This study proved that Korean medicine treatment could be effective for the clearance of VRE colonization and improvement of symptoms.

Modern Interpretation of the Method of Learning Reflected in the Teacher-Student Relationship in On Haeng Lok by Toe-gye (퇴계 『언행록』의 사제관계에서 탐색한 학습법과 그 현대적 이해)

  • Shin, Chang-Ho;Chi, Chun-Ho;Lee, Seung-Chul;Sim, Seung-Woo
    • The Journal of Korean Philosophical History
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    • no.56
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    • pp.209-238
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    • 2018
  • The purpose of this research is to analyze characteristics of the method of education or learning reflected in the teacher-student relationship in On Haeng Lok By Toe-gye and explore their relevance to modern education. By writing various works and conversing with his students, Toe-gye devoted himself in the education of the traditional Confucian principles. Specially, he taught his students based on two Confucian educative principles, namely Shim Deuk(心得) and Goong Haeng(躬行). Judging from this, Toe-gye can be seen as someone who tries to fulfill the role of teacher as dictated in the educative principles of the Confucianism. In Confucianism, teacher is responsible for forming a well-rounded view on life in student, rather than simply transmitting knowledge. As such, the teacher was supposed to find a harmonious way to create something new based on what was inherited from the past generation and try to do his best in learning new things himself and teaching his students. These Toe-gye managed to do successfully, earning his students' trust and respect. Being moved and inspired by their teacher, the students continued their intellectual pursuit. This relationship between Toe-gye and his students can be analyzed from the perspective of education method and discussed in terms of cognitive learning and adult learning. In terms of cognitive learning, the education method reflected in the relationship is similar to potential learning, insight learning, and imitation learning. In terms of adult learning, it is similar to self-directed learning and communicative learning.!

Gu-am Kim Kyung Jang's Life and Learning (구암(龜巖) 김경장(金慶長)의 생애(生涯)와 학문(學問))

  • Yoo, Kwon Jong
    • (The)Study of the Eastern Classic
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    • no.33
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    • pp.57-96
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    • 2008
  • Kim, Kyung Jang(1597~1653) as a disciple of Jang Hyun Gwang was very famous for his virtuous conduct. But his collection of works has been published recently. There has never been any studies about his thoughts, learning and life. Therefore this study has a target to arrange the process of his life and events, and to introduce outlines of his learning. The items of this study will be as follows: The first category will be his lineage, his life, and writings. The second category will be his learning. This category has two lower categories. The first will be focused on his intention to morally accomplished self by the method of self cultivation and practise of Confucian proprieties. The second will be focused on his learning of the Change and of the Confucian proprieties. And giving attention to his 6 diagrams that have symbolized principles of the Change, this paper tries to compare these to the other scholars ones and so will explane the features of his diagrams. The most important thing in this paper is to define his learning as so called in the rhetoric of Confucianism Wi-gi-ji-hak(爲己之學), which means self organization of one's moral personality by the method of self cultivation and to distinguish the steps of his learning developed. This method has never been applied, but this is expected to become a effective method for explanation of the truth of the Confucian scholar's world of learning.

A Case Report of Korean Medicine Treatment of a Lung Cancer Patient with Chemotherapy-induced Peripheral Neuropathy (편평상피세포 폐암 환자의 항암화학요법에 의해 유발된 말초신경병증에 대한 한방치험 1례)

  • Kim, Kyun Ha;Kim, Min-hwa;Heo, Gi-yoon;Lee, Chan;Cho, Im-hak;Kang, Hee-kyung;Kim, So-yeon;Park, Seong-ha;Yun, Young-ju;Lee, In;Han, Chang-woo;Hong, Jin-woo;Kwon, Jung-nam;Choi, Jun-Yong
    • The Journal of Internal Korean Medicine
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    • v.42 no.6
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    • pp.1341-1348
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    • 2021
  • The purpose of this study is to report the effect of Korean medicine on a squamous cell lung cancer patient with chemotherapy induction peripheral neuropathy (CIPN). A 61-year old male patient, who had received 4 cycles of chemotherapy after lung surgery from squamous cell lung cancer, was treated with acupuncture and herbal medicines, including Uchasingi-hwan and Samchilchoongcho-capsule, to control CIPN and dyspnea on exertion. The degree of pain was assessed by a numeric rating scale (NRS). After receiving acupuncture and herbal medicines, the NRS score for CIPN symptoms was reduced from 4 to 1 and the NRS score for dyspnea on exertion decreased from 3 to less than 1. Korean medicine could therefore be useful in reducing peripheral neuropathy occurring after chemotherapy and dyspnea after lobectomy.

Analysis of mercury and methylmercury in river sediment samples (하천퇴적물 중의 수은 및 메틸수은 분석 연구)

  • Lee, Jung-Sub;Park, Jae-Sung;Kang, Hak-Gu;Cho, Jae-Seok;Hong, Eun-Jin;Jeong, Gi-Taeg;Cha, Jun-Seok;Jung, Kwang-Yong;Kim, Young-Hee
    • Analytical Science and Technology
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    • v.22 no.1
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    • pp.44-50
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    • 2009
  • In this study, the use of purge & trap GC-MS technique for determination of methylmercury in sediment samples was described. The method detection limit of the method was determined as 0.06 ng/g and the recovery of the method was $102{\pm}11.4%$, with precisions better than 11.2%. The method was validated by analysis of CRMs such as ERM CC580 (estuarine sediment) and IAEA 405 (sediment). Additionally, the performance of the method was tested on river sediment samples and the analytical results were compared with those of the GC-CVAFS, which has been widely used for methylmercury analysis.

Hypoglycemic Effect of Smallanthus sonchifolius (Yacon) Extracts on Animals with Streptozotocin-induced Diabetes (야콘 추출물이 Streptozotocin으로 유도된 당뇨 동물모델에서 혈당강하에 미치는 효과)

  • Oh, Hong-Geun;Kang, Young-Rye;Kim, Jung-Hoon;Moon, Dea-In;Seo, Min-Young;Park, Sang-Hoon;Choi, Kwang-Ho;Kim, Chang-Ryong;Kim, Sang-Hyun;Oh, Ji-Hyun;Kim, Sun-Young;Kim, Min-Gul;Chae, Soo-Wan;Kim, Ok-Jin;Lee, Hak-Yong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.6
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    • pp.759-765
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    • 2012
  • This study was performed to investigate improvements in diabetes mellitus by extracts of yacon in streptozotocin (STZ)-induced diabetic rats. Fifty rats were divided into a normal group and four experimental groups. STZ (45 mg/kg) was injected intraperitoneally to induce type I diabetes in the four experimental groups. Yacon extracts were administered for 5 weeks. Forty-five ICR mice were also divided into one positive control group and four experimental groups for the oral glucose tolerance test (OGTT) after fed yacon extract. The control group did not eat any yacon extracts, while Group 1 (GI) was fed 125 mg/kg of yacon extracts, Group 2 (GII) was fed 250 mg/kg of yacon extracts, and Group 3 (GIII) was fed 500 mg/kg of yacon extracts. After treatment for 5 weeks, blood glucose in GIII group showed decreased tendency at the 5 week. In OGTT by glucose, the glucose level of yacon treatment group in diabetic rats was significantly decreased compared to the glucose level of the control group, but there was no difference in OGTT by maltose. In ICR mice, the glucose level of the experimental group in OGTT by maltose was significantly decreased compared to the control group. The area of the islets of Langerhans was increased by yacon treatment in a dose-dependent manner on diabetic rats. Insulin concentration of the GIII group was also decreased compared to the control group, while the concentration of fructosamine, total cholesterol, and triglycerides in serum showed no difference. OGTT by glucose or maltose in ICR mice or diabetic rats, area of the Islets of Langerhans, and insulin concentration improved. Yacon treatment may be a useful therapeutic and preventive strategy for diabetes mellitus.

In the Treatment I-131, the Significance of the Research that the Patient's Discharge Dose and Treatment Ward can Affect a Patient's Kidney Function on the Significance of Various Factors (I-131 치료시 환자의 신장기능과 다양한 요인으로 의한 퇴원선량 및 치료병실 오염도의 유의성에 관한 연구)

  • Im, Kwang Seok;Choi, Hak Gi;Lee, Gi Hyun
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.1
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    • pp.62-66
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    • 2013
  • Purpose: I-131 is a radioisotope widely used for thyroid gland treatments. The physical half life is 8.01 and characterized by emitting beta and gamma rays which is used in clinical practice for the purpose of acquiring treatment and images. In order to reduce the recurrence rate after surgery in high-risk thyroid cancer patients, the remaining thyroid tissue is either removed or the I-131 is used for treatment during relapse. In cases of using a high dosage of radioactive iodine requiring hospitalization, the patient is administered dosage in the hospital isolation ward over a certain period of time preventing I-131 exposure to others. By checking the radiation amount emitted from patients before discharge, the patients are discharged after checking whether they meet the legal standards (50 uSv/h). After patients are discharged from the hospital, the contamination level is checked in many parts of the ward before the next patients are hospitalized and when necessary, decontamination operations are performed. It is expected that there is exposure to radiation when measuring the ward contamination level and dose check emitted from patients at the time of discharge whereby the radiation exposure by health workers that come from the patients in this process is the main factor. This study analyzed the correlation between discharge dose of patients and ward contamination level through a variety of factors such as renal functions, gender, age, dosage, etc.). Materials and Method: The study was conducted on 151 patients who received high-dosage radioactive iodine treatment at Soon Chun Hyang University Hospital during the period between 8/1/2011~5/31/2012 (Male: Female: 31:120, $47.5{\pm}11.9$, average dosage of $138{\pm}22.4$ mCi). As various factors expected to influence the patient discharge dose & ward contamination such as the beds, floors, bathroom floors, and washbasins, the patient renal function (GFR), age, gender, dosage, and the correlation between the expected Tg & Tg-Tb expected to reflect the remaining tissue in patients were analyzed. Results: In terms of the discharge dose and GFR, a low correlation was shown in the patient discharge dose as the GFR was higher (p < 0.0001). When comparing the group with a dosage of over 150mCi and the group with a lower dosage, the lower dosage group showed a significantly lower discharge dose ($24{\pm}10.4uSv/h$ vs $28.7{\pm}11.8uSv/h$, p<0.05). Age, gender, Tg, Tg-Tb did not show a significant relationship with discharge dose (p> 0.05). The contamination level in each spot of the treatment ward showed no significant relationship with GFR, Tg, Tg-Tb, age, gender, and dosage (p>0.05 ). Conclusion: This study says that discharge of the dose in the patient's body is low in GFR higher and Dosage 150mCi under lower. There was no case of contamination of the treatment ward, depending on the dose and renal association. This suggests that patients' lifestyles or be affected by a variety of other factors.

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Effects of Supplementation of Trace Nutrients on Hanwoo Heifers (Bos taurus coreanae) under Hilly Pasture Grazing System (산지 방목기간 중 미량영양소 급여가 한우 암소의 생산성에 미치는 영향)

  • Yang, Seung Hak;Yang, Byoung Chul;Chung, Ki Yong;Jang, Sun Sik;Lee, Eun Mee;Cho, Sang Rae;Lee, Suk Dong;Park, Hyung Soo;Kwon, Eung Gi
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.36 no.4
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    • pp.387-392
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    • 2016
  • This study was conducted to ameliorate the productive performance of Hanwoo cow using hill pasture grazing system. Twenty seven animals aged 9 were designed to divide with 3 groups which were Control (restricted concentrate and hay for 5 months), T1 (restricted concentrate and pasture grazing ad libitum for 5 months) and T2 (restricted concentrate, 30 g/head of mineral nutrients and pasture grazing ad libitum for 5 months). Average daily gains increased higher in the order of T2, Control and T1. The conception rate of Control, T1 and T2 after artificial insemination during post-grazing period were 88.9%, 100%, 100%, respectively. In conclusion, the results indicated that hill pasture grazing system might enhance not only the productive performance of Hanwoo cow but also profit for conventional feeding system.

Evaluation on Heavy Metal Contents in Agricultural Soils around Industrial Complexes in Korea (공단 인근 농경지 토양 중 중금속 함량 평가)

  • Yun, Sun-Gang;Chae, Mi-Jin;Kim, Yoo-Hak;Kong, Myung-Suk;Jung, Ha-il;Kim, Suk-Cheol;Kim, Myoung-Suk;Park, Seong-Jin;Lee, Chang-Hoon;Yang, Jae-E;Kim, Sung-Chul;Kim, Gi-In;Kim, Gwon-Rae;Jung, Goo-Bok
    • Korean Journal of Environmental Agriculture
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    • v.37 no.2
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    • pp.141-145
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    • 2018
  • BACKGROUND: Agricultural soils are vulnerable from contamination of heavy metal derived from industrial waste. Monitoring on heavy metals on agricultural soils around industrial complexes and evaluation on distributional state on the concentrations of heavy metals in soil have been carried out for problem assessment on soil condition. METHODS AND RESULTS: Soil samples of 1,200, were collected from sixty site of industrial complexes located Gyounggi, Chungbuk, Cheonbuk, and Gyoungnam provinces. Total concentration of Cu, Pb, Zn, Ni, and As were analyzed. Heavy metal concentrations in most soil samples were below warning criteria, except 1 site of Pb, Ni, and As, separately. The comparison of mean values of heavy metal concentrations between soils around industrial complexes and paddy soils, showed similar levels of heavy metals, except Pb. The concentrations of lots of heavy metals were distributed between from warning criteria to one fifth level of warning criteria. However, in the case of Cu and Pb, more than 30% were distributed below one twenties level of warning criteria. These results were very similar with the distribution state of heavy metals in upland soils. The concentrations of heavy metals in surface soil and subsoil were similar among the heavy metals in soils around industrial complexes. CONCLUSION: The concentrations of heavy metals in soils around industrial complexes were distributed close to warning criteria. Long term and continous monitoring and evaluation on heavy metals in agricultural soils are required for food safety and sustainable soil management.

Antifungal Activity of Bacillus sp. AM-651 Against Phytophthora capsici (고추역병 유발병원균 Phytophthora capsici에 대한 Bacillus sp. AM-651의 항진균활성)

  • Lee, Jung-Bok;Shin, Jeong-Hak;Jang, Jong-Ok;Shin, Kee-Sun;Choi, Chung-Sik;Kim, Kun-Woo;Jo, Min-Sub;Jeon, Chun-Pyo;Kim, Yun-Hoi;Kwon, Gi-Seok
    • Microbiology and Biotechnology Letters
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    • v.36 no.3
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    • pp.227-232
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    • 2008
  • Biological antagonists of Phytophthora capsici were isolated from soil in Gyeongbuk, Korea. Among the isolated bacteria, a Bacillus sp. was identified from l6S rDNA sequence analysis and named Bacillus sp. AM-651. Bacillus sp. AM-65l strain which can strongly a antifungal activity against Phytophthora capsici. Culture conditions for the maximum production of the antagonistic substance were optimized. The production of antibiotic were high on modified Davis mineral medium pH 7 at $30^{\circ}C$. The medium for highest production of the agonistic substance optimized. It is composed the best activity on glucose, $(NH_4)_2SO_4$ and $K_2HPO_4$ at 0.5%, 0.1%, and 0.7%, respectively. By time course of culture solution selected Bacillus sp. AM-65l, the culture solution after 48hrs had strongly growth inhibition rate against P. capsici. And culture solution of Bacillus sp. AM-651 was stable within a pH range $5{\sim}11$ and temperature range $4{\sim}70^{\circ}C$. Bacillus sp. AM-651 cultured broth shown fungal growth inhibitory activity against B. sorokiniana, B. cinerea, R. solani avove and beyond P. capsici and comparatively showed a high activity against C. gloeosporioides, B. dothidea, B. cinerea and F. graminearum by agar diffusion method.