• Title/Summary/Keyword: Genetic stability

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A Design of MGA-Pl Supplementary Controller in SVC for Power Oscillation Damping of HVDC Transmission System (초고압 직류송전 시스템의 전력 동요억제를 위한 정지형 무효전력 보상기에 MGA-PI 보조제어기 설계)

  • O, Tae-Gyu;Jeong, Hyeong-Hwan;Heo, Dong-Yeol;Lee, Jeong-Pil
    • The Transactions of the Korean Institute of Electrical Engineers A
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    • v.51 no.7
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    • pp.317-326
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    • 2002
  • In this paper, a methodology for optimal PI supplementary controller using the modified genetic algorithm has been proposed to the oscillation damping in HDVC transmission system. These study processes are summarized as the formulation for load flow calculation in HVDC transmission system with SVC, the investigations on the basic control in HVDC system, the mathematical modeling for dynamic characteristics analyses, and the optimal design of MGA based PI controller generation the supplementary control signal of SVC. Its properties were verified through a series of computer simulations including dynamic stability. It means that the application of MGA-PI controller in HVDC transmission system can contribute the propriety to the improvement of the stability in HVDC transmission system and the design of MGA-OI controller has been proved indispensible when applied to HVDC transmission system.

Shoot Induction and Genetic Stability of in vitro Cultured Pea

  • Kantayos, Vipada;Bae, Chang-Hyu
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.30-30
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    • 2019
  • Pea (Pisum sativum) is one of important legume crops in the world. It is commonly used as a protein source for animal and human diet, and also used as a natural nitrogen source which is produced by a symbiotic bacterium in their root nodule and helpful for terrestrial ecosystem. The successful in vitro manipulation is depended on three main factors including physiology of plant donor, in vitro manipulation approach, and stress physiology during plant cultivation. Moreover, genotype is an important for plant manipulation; different genotype gives the different response to regeneration efficiency. An efficient condition of shoot induction for pea (Pisum sativum cv. 'Sparkle') was developed by using optimum explant, plant growth regulator concentrations, and pretreatment of BA onto explant. The average shoot number per explant showed the highest on two kinds of shoot induction media (MSB5 media containing 2 mg/L BA and a combination of 2 mg/L BA and 1 mg/L TDZ) with cotyledonary node explants culture. Moreover, the pretreatment of explant in 200 mg/L BA solution was found to be more effective in shoot induction than that of non-pretreatment. The analysis of genetic stability of regenerants by using 13 ISSR markers presented that in vitro regenerated plants showed polymorphism with 8.3% compared with their mother plants.

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Stable Walking for an Inverted Pendulum Type Biped Robot (도립 진자형 이족보행로봇을 위한 안정보행)

  • Kang, Chan-Su;Noh, Kyung-Kon;Kim, Jin-Geol
    • Proceedings of the KIEE Conference
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    • 2003.11c
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    • pp.456-459
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    • 2003
  • This paper deal with the biped walking stability by inverted pendulum type balancing joints. This model is hard to interpretation for the nonlinearity caused by upper direction movement then conventional model which have roll and prismatic joints. We can interpret this model by a linear approximation or interpolation method. This paper use a linear approximation method that can decide a movement of upper direction. Inverted pendulum type balancing joints have a advantage of less movement for keep stability and similar with human than conventional model and this model can be used for humanoid robot. We can see a stability of biped by ZMP(Zero Moment Point). Genetic algorithm is used for trajectory planning that is important for stable walking of biped.

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Multi-objective optimization of double wishbone suspension of a kinestatic vehicle model for handling and stability improvement

  • Bagheri, Mohammad Reza;Mosayebi, Masoud;Mahdian, Asghar;Keshavarzi, Ahmad
    • Structural Engineering and Mechanics
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    • v.68 no.5
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    • pp.633-638
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    • 2018
  • One of the important problems in the vehicle design is vehicle handling and stability. Effective parameters which should be considered in the vehicle handling and stability are roll angle, camber angle and scrub radius. In this paper, a planar vehicle model is considered that two right and left suspensions are double wishbone suspension system. For a better analysis of the suspension geometry, a kinestatic model of vehicle is considered which instantaneous kinematic and statics relations are analyzed simultaneously. In this model, suspension geometry is considered completely. In order to optimum design of double wishbones suspension system, a multi-objective genetic algorithm is applied. Three important parameters of suspension including roll angle, camber angle and scrub radius are taken into account as objective functions. Coordinates of suspension hard points are design variables of optimization which optimum values of them, corresponding to each optimum point, are obtained in the optimization process. Pareto solutions for three objective functions are derived. There are important optimum points in these Pareto solutions which each point represents an optimum status in the model. In other words, corresponding to any optimal point, a specific geometric position is determined for the suspension hard points. Each of the obtained points in the Pareto optimization can be selected for a special design purpose by designer to create an optimum condition in the vehicle handling and stability.

A Study of the Potential Shelters in the Lunar Lava Tubes (달 동굴의 잠재적 주거환경에 관한 연구)

  • Oh, Jongwoo
    • Journal of Satellite, Information and Communications
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    • v.12 no.3
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    • pp.41-49
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    • 2017
  • This paper will describe lunar lava tubes' five analyzed fields, such as geology, geomorphology, internal configuration, stability, communication and habitats requirements. This research gets through qualitative and qualitative data analysis as following results. A huge size and configuration differences between lunar lava tubes and earth one on geology and landform environments. Exo-genetics activities, such as meteorites, radiation, and sudden temperature bigger affect than Endo-genetic activities, such as effusion and earthquake of the lunar lava tubes. Landform and internal configuration of the lunar lava tubes due to the huge cave perilous landform that gravity difference have a technical limitation from internal approach and data obtain of the huge skylights and sinuous rilles. Stability of the lunar lava tubes deals with geology and landform. It was obvious geo-structural stability elements results generated on low rate of collapsed halls(skylights), low gravity, and relatively thick covers. In terms of the communication capability on the external and internal lunar lava tubes cordless communication techniques will overcome limitations of the sun-power generates supporting communication systems. Through this research it realized obvious differs between potential habitats possibility by accumulative theories by scholars and techniques of the lunar lava tubes. Especially, it is a favorable expectation throughout overcoming attempt on zero gravity, cosmo radiation, lunar dust of the exo-genetic limitations to the steep escarpment of skylights to approach and achieve techniques by the civil engineering, networking and GIS techniques as the endo-genetic environment treatment.

Immobilization and Characterization of Rifamycin B Oxidase in Cellulose Acetate Beads (셀룰로오스 아세테이트에 고정화된 리파마이신 B 산화효소의 특성)

  • Chung, Bong-Hyun;Chang, Ho-Nam;Han, Moon-Hi
    • Microbiology and Biotechnology Letters
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    • v.13 no.2
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    • pp.115-118
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    • 1985
  • Rifamycin B oxidase converts rifamycin B to rifamycin S using oxygen as cosubstrate. Humnicola spp. (ATCC 20620) was treated with acetone and the cell powder was immobilized with cellulose acetate. The properties of the immobilized enzyme was examined. The optimum pHs of the immobilized and the free enzymes were 7.2. The optimum temperature of the immobilized enzyme was at 50-55$^{\circ}C$, which was 5$^{\circ}C$ higher than that of the free enzyme. The activities of the immobilized enzyme appeared less sensistive with respect to the changes of temperature and pH as compared to those of the free enzyme. Twenty percent of the enzyme activity was recovered when the enzyme was immobilized in 3mm beads. The storage stability was good below 4$0^{\circ}C$, but the activity decreased very rapidly above 5$0^{\circ}C$. The physical strength of the beads was good and was suitable as packing material in a three-phase enzyme reactor.

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Performance of Heritabilities, Genetic Correlations and Path Coefficients of Some Agronomic Traits at Different Cultural Environment in Sesame

  • Shim, Kang-Bo;Kang, Chul-Whan;Lee, Sung-Woo;Kim, Dong-Hee;Lee, Bong-Ho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.45 no.4
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    • pp.245-250
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    • 2000
  • This study was conducted to analyze the responses of some agronomic traits to the different cultural environments and relations among the agronomic traits for selecting sesame varieties with higher cultural stabilities. The indexes for stability parameters measured were coefficient of variability, heritabilities, genetic correlations and path coefficients of agronomic traits according to locations and years in Korea. The heritabilities of agronomic traits showed different by locations and years. Number of seeds per capsule and 1000 seeds weight showed higher heritabilities, but stem length and seed weight per plant showed relatively lower heritabilities. Average heritabilities of some agronomic traits in 1998 were comparatively higher than those of 1999. Of six areas, Jinju area showed biggest coefficient of yield variability in 1998-1999. Iksan and Taegu areas showed higher heritabilities in 1998, but Iksan and Jinju areas showed lower heritabilities in 1999. Genetic correlations were slightly higher than corresponding phenotypic correlations. Stem length showed positive genetic correlation with the number of capsules per plant, and seed weight per plant and the number of capsule per plant showed positive genetic correlation with seed weight per plant. On the analysis of path coefficients, stem length and number of capsules effected highly on grain yield. Great regional variations were observed on the effects of agronomic traits on grain yield. Higher direct effects of stem length on grain yield were observed at Suwon, Chungwon, Taegu, Jinju and Naju areas, but in Iksan area was observed higher direct effect of the number of capsules per plant on grain yield in 1998. In 1999, higher direct effect of stem length on grain yield was observed at Chungwon and Suwon areas. Iksan and Taegu areas were also observed higher direct effect of the number of capsule per plant on grain yield.

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Multi-epitope vaccine against drug-resistant strains of Mycobacterium tuberculosis: a proteome-wide subtraction and immunoinformatics approach

  • Md Tahsin Khan;Araf Mahmud;Md. Muzahidul Islam;Mst. Sayedatun Nessa Sumaia;Zeaur Rahim;Kamrul Islam;Asif Iqbal
    • Genomics & Informatics
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    • v.21 no.3
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    • pp.42.1-42.23
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    • 2023
  • Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, one of the most deadly infections in humans. The emergence of multidrug-resistant and extensively drug-resistant Mtb strains presents a global challenge. Mtb has shown resistance to many frontline antibiotics, including rifampicin, kanamycin, isoniazid, and capreomycin. The only licensed vaccine, Bacille Calmette-Guerin, does not efficiently protect against adult pulmonary tuberculosis. Therefore, it is urgently necessary to develop new vaccines to prevent infections caused by these strains. We used a subtractive proteomics approach on 23 virulent Mtb strains and identified a conserved membrane protein (MmpL4, NP_214964.1) as both a potential drug target and vaccine candidate. MmpL4 is a non-homologous essential protein in the host and is involved in the pathogen-specific pathway. Furthermore, MmpL4 shows no homology with anti-targets and has limited homology to human gut microflora, potentially reducing the likelihood of adverse effects and cross-reactivity if therapeutics specific to this protein are developed. Subsequently, we constructed a highly soluble, safe, antigenic, and stable multi-subunit vaccine from the MmpL4 protein using immunoinformatics. Molecular dynamics simulations revealed the stability of the vaccine-bound Tolllike receptor-4 complex on a nanosecond scale, and immune simulations indicated strong primary and secondary immune responses in the host. Therefore, our study identifies a new target that could expedite the design of effective therapeutics, and the designed vaccine should be validated. Future directions include an extensive molecular interaction analysis, in silico cloning, wet-lab experiments, and evaluation and comparison of the designed candidate as both a DNA vaccine and protein vaccine.

In vitro Regeneration and Genetic Stability Analysis of the Regenerated Green Plants in Japanese Blood Grass (Imperata cylindrica 'Rubra') (홍띠 기내 재생과 재생 녹색식물체의 유전적 안정성)

  • Kang, In-Jin;Lee, Ye-Jin;Bae, Chang-Hyu
    • Korean Journal of Plant Resources
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    • v.34 no.2
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    • pp.156-165
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    • 2021
  • The in vitro regeneration was established, and the genetic stability among the mother plants (control) and the micropropagated green plants was evaluated using ISSR markers in Imperata cylindrica 'Rubra', Poaceae which containing important bioenergy plants. Green shoots were multiply induced from growing point culture via callus on MS medium supplemented with 0.01 mg/L NAA and 2 mg/L BA, and the shoots were proliferated on the MS medium with rooting. Rooted plantlets were transplanted to the pot with 100% survival rate. Using ISSR markers, somaclonal variation was analyzed in eight mother plants (control), ten green-regenerant cultivated at culture room (ReR) and ten green-regenerant cultivated at field condition (ReF). All ISSRs produced a total of 97 bands, and the scorable bands varied from one to seven with an average of 4.4 bands per primer. The polymorphism rate of ReRs and ReFs was 4.1% and 3.1% respectively, showing higher rate than that of control (0%). The genetic similarity matrix (GSM) among all accessions ranged from 0.919 to 1.0 with a mean of 0.972. According to the clustering analysis, ReFs and mother plants were divided into two independent groups. The results indicate that no clear genetic diversity was detected among regenerated plants, and ISSR markers were useful tool for identification of somaclonal variation of regenerants.

Structural and Functional Stability of the Genetic Recombinant Plasmid pCU103 in Different Water Environments

  • Kim, Chi-Kyung;Kwak, Myoung-Ja;Lee, Sung-Gie
    • Journal of Microbiology
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    • v.34 no.3
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    • pp.241-247
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    • 1996
  • The stability of the genetically engineered microorganisms and their recombinant plasmids released in natural environments has been regarded as one of the molecular ecological topics. In this study, the recombinant plasmids pCU103 in which the pcbCD genes involved in biodegradation of biphenyl and 4-chlorobiphenyl were cloned in pBluescript SK(+) vector, were examined for their structural and functional stability in different waters at 15 $^{\circ}C$ by the methods of electrophoresis, Southern hybridization, quantification with fluorescent dye, and transformation. The recombinant plamids maintained their stabilities for about 30 days in sterilized distilled water (SDW), 15 days in autoclaved creek water (AW), 25 days in filtered and autoclaved non-sterile creek water (FAW), 4 days in Luria-Bertani (LB) broth, and less than one day in filtered non-sterile creek water (FW). The covalently closed circular (CCC) form of the plasmid was decreased and open circular (OC) form was increased as a function of incubation time, and then linear (L) form was produced to be ultimately degraded out. The degradation rates of the plasmid were proportionally correlated to trophic level of the water, and the biological factor such as DNases was found to be one of the most critical factors affecting structural and functional stability of the plasmid in non-sterile natural water.

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