• 수산해양기술연구
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• 제59권2호
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• pp.145-154
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• 2023

In this study, to control the heading angle of a ship, which is constantly subjected to various internal and external disturbances during the voyage, an LADRC (linear active disturbance rejection control) design that focuses more on improving the disturbance removal performance was proposed. The speed rate of change of the ship's heading angle due to the turn of the rudder angle was selected as a significant factor, and the nonlinear model of the ship's maneuvering equation, including the steering gear, was treated as a total disturbance. It is the similar process with an LADRC design for the first-order transfer function model. At this time, the gains of the controller included in LADRC and the gains of the extended state observer were tuned to RCGAs (real-coded genetic algorithms) to minimize the integral time-weighted absolute error as an evaluation function. The simulation was performed by applying the proposed GA-LADRC controller to the heading angle control of the Mariner class vessel. In particular, it was confirmed that the proposed controller satisfactorily maintains and follows the set course even when the disturbances such as nonlinearity, modelling error, uncertainty and noise of the measurement sensor are considered.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.196-203
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• 2022

The resource constrained scheduling problem (RCSP) constitutes one of the most challenging problems in Project Management, as it combines multiple parameters, contradicting objectives (project completion within certain deadlines, resource allocation within resource availability margins and with reduced fluctuations), strict constraints (precedence constraints between activities), while its complexity grows with the increase in the number of activities being executed. Due to the large solution space size, this work investigates the application of Genetic Algorithms to approximate the optimal resource alolocation and obtain optimal trade-offs between different project goals. This analysis uses the cost of exceeding the daily resource availability, the cost from the day-by-day resource movement in and out of the site and the cost for using resources day-by-day, to form the objective cost function. The model is applied in different case studies: 1 project consisting of 10 activities, 4 repetitive projects consisting of 40 activities in total and 16 repetitive projects consisting of 160 activities in total, in order to evaluate the effectiveness of the algorithm in different-size solution spaces and under alternative optimization criteria by examining the quality of the solution and the required computational time. The case studies 2 & 3 have been developed by building upon the recurrence of the unit/sub-project (10 activities), meaning that the initial problem is multiplied four and sixteen times respectively. The evaluation results indicate that the proposed model can efficiently provide reliable solutions with respect to the individual goals assigned in every case study regardless of the project scale.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2022년도 추계학술대회
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• pp.68-68
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• 2022

The pepper mild mottle virus (PMMoV), belonging to the tobamovirus genus, is currently one of the most destructive pathogens in pepper production. Tobamoviruses have been classified in terms of increased pathogenicity as pathotypes P₀, P₁, P_1,2, P_1,2,3 and P_1,2,3,4, based on their ability to infect systemically Capsicum L⁰ , L¹ , L² , L³ and L⁴ resistant plants, respectively. Two hundred eighty pepper germplasms and 5 reference accessions known as resistant L alleles, were analyzed to select the resistance cultivars against PMMoV- P_1,2,3 (CV130614-2) using bioassay and genetic markers. The susceptible accessions showed systemic symptom when inoculated with PMMoV- P_1,2,3. However, accessions including IT223737, were resistant as they developed necrotic local lesions only on inoculated leaves, whereas no symptoms were observed on the upper leaves. Moreover, RT-PCR results for detecting the presence of virus were also negative. Thus, those accessions will be used as a novel source to facilitate introduction the resistant gene into commercial cultivars of pepper.

• Journal of Forest and Environmental Science
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• 제40권2호
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• pp.111-117
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• 2024

An evaluation was carried out on variability in morphology of fruits and seeds (number and weight) of Tetrapleura tetraptera (Schumach. and Thonn.) Taub. from different populations across its distribution range in Nigeria. Bulk fruit samples were collected and examined for variations in morphological characters. Differences in morphological character of fruits and seeds among the populations were determined using analysis of variance at 5% level of probability. The relationships among morphological characters were determined using Pearson correlation coefficient (r). Significant variations (p<0.05) existed among T. tetraptera populations for all the evaluated characters: fruit length, fruit width, number of seeds per fruit and seed weight. A positive significant strong correlation (r=0.96) was found between seed weight and number of seeds per fruit, while no correlation existed between fruit length, width and number of seeds. Seed weight was positively correlated with minimum altitude (r=0.97) and maximum altitude (r=0.99) of seed populations. Number of seeds was also significantly correlated with maximum altitude (r=0.965). There was no significant correlation between geo-climatic variables and fruit dimensions (length and width). Observed variations in morphological traits within and across populations of T. tetraptera may be used as proxy to estimate genetic diversity and selection of superior trees for improved productivity.

• 생명과학회지
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• 제32권4호
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• pp.279-284
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• 2022

본 연구는 일반농가에서 적용 가능한 유전평가시스템을 구축을 위해 경기 지역에서 사육중인 암소 619두를 BLUP (Best Linear Unbiased Prediction)과 GBLUP (Genomic Best Linear Unbiased Prediction)을 사용하여 각 형질(도체중, 등심단면적, 등지방두께, 근내지방도) 별 추정 육종가의 정확도를 비교분석 하였다. GBLUP의 경우 참조집단의 크기를 다르게 그룹을 나누어 분석하였다. 분석결과 GBLUP 참조집단의 크기가 커질수록 각 형질의 육종가의 정확도도 상승하는 것을 확인 하였다. BLUP과 GBLUP 방법을 사용하여 추정한 육종가의 정확도를 비교하면, GBLUP 방법을 사용하여 육종가를 추정하였을 때 도체중, 등심단면적, 등지방두께 근내지방도순으로 각각 0.10, 0.09, 0.09, 0.11 이상 상승한 것을 확인할 수 있었다. 따라서, GBLUP 방법을 암소 평가 및 선발에 적용한다면, 정밀하고 정확한 개체 선발이 가능하고 참조집단의 크기를 더욱 키운다면 보다 정확한 개체 선발을 할 수 있기 때문에 선발의 효율성이 증가할 것으로 사료된다.

• Archives of Pharmacal Research
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• 제19권4호
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• pp.251-257
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• 1996

The detection of many synthetic chemicals used in industry that may pose a genetic hazard in our environment is subject of great concern at present. In this respect, the genetic toxicity of fenpropathrin ((RS)-.alpha.-cyano-3-phenoxybenzyl-2,2,3,3-tetramethyl cyclopropane carboxylate, CAS No.:39514-41-8), a pyrethroid insecticide, was evaluated in bacterial gene mutation system, chromosome aberration in mammalian cell system and in vivo micronucleus assay with rodents. In bacterial gene mutation assay, no mutagenicity of fenpropathrin (62-$5000\mug/plate$) was observed in Salmonella typhimurium TA 98, 100, 1535 and 1537 both in the absence and in the presence of S-9 metabolic activaton system. In mammalian cell system using chinese hamster lung fibroblast, no clastogenicity of fenpropathrin was also observed both in the absence and in the presence of metabolic activation system in the concentration range of $7-28\mug/ml$. And also, in vivo micronucleus assay using mouse bone marrow cells, fenpropathrin also revealed no mutagenic potential in the dose range of 27-105 mg/kg body weight of fenpropathrin (i.p.). Consequently, no mutagenic potential of fenpropathrin was observed in vitro bacterial, mammalian mutagenicity systems and in vivo micronucleus assay in the dose ranges used in this experiment.

• 산업경영시스템학회지
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• 제36권4호
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• pp.116-122
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• 2013

This study develops a dynamic scheduling model for parallel machine scheduling problem based on genetic algorithm (GA). GA combined with discrete event simulation to minimize the makespan and verifies the effectiveness of the developed model. This research consists of two stages. In the first stage, work sequence will be generated using GA, and the second stage developed work schedule applied to a real work area to verify that it could be executed in real work environment and remove the overlapping work, which causes bottleneck and long lead time. If not, go back to the first stage and develop another schedule until satisfied. Small size problem was experimented and suggested a reasonable schedule within limited resources. As a result of this research, work efficiency is increased, cycle time is decreased, and due date is satisfied within existed resources.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권8호
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• pp.3474-3497
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• 2016

Network Function Virtualization (NFV) and Software Defined Networking (SDN) are recently considered as very promising drivers of the evolution of existing middlebox services, which play intrinsic and fundamental roles in today's networks. To address the virtual service deployment issues that caused by introducing NFV or SDN to networks, this paper proposes an optimal solution by combining quantum genetic algorithm with cooperative game theory. Specifically, we first state the concrete content of the service deployment problem and describe the system framework based on the architecture of SDN. Second, for the service location placement sub-problem, an integer linear programming model is built, which aims at minimizing the network transport delay by selecting suitable service locations, and then a heuristic solution is designed based on the improved quantum genetic algorithm. Third, for the service amount placement sub-problem, we apply the rigorous cooperative game-theoretic approach to build the mathematical model, and implement a distributed algorithm corresponding to Nash bargaining solution. Finally, experimental results show that our proposed method can calculate automatically the optimized placement locations, which reduces 30% of the average traffic delay compared to that of the random placement scheme. Meanwhile, the service amount placement approach can achieve the performance that the average metric values of satisfaction degree and fairness index reach above 90%. And evaluation results demonstrate that our proposed mechanism has a comprehensive advantage for network application.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제20권1호
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• pp.3-9
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• 2009

Objectives : Tourette disorder is known to be a disease with a strong genetic trait. There has been some recent research on the relationship between the allelic frequency distribution and Tourette disorder. In Korea, the relationship between the genetic type and the alleles for the COMT gene has been studied in Tourette patients. Methods : Seventy two patients who were diagnosed with Tourette disorder according to the DSM-IV diagnostic criteria were selected for this study. The diagnosis and clinical features were confirmed by the Yale Global Tic Severity Scale. For the control group, the parents of the patients were chosen. Blood samples were taken from the 289 subjects. DNA was extracted from the blood lymphocytes and PCR was performed for assessing COMT gene. Results : On comparing the Tourette disorder transmitted group and the not-transmitted group, no significant difference was seen between the COMT genetic type and the allelic distribution. Conclusion : Even though this result is viewed that there is no relationship between Tourette disorder and the COMT gene, it is difficult to firmly accept this negative result. Follow up studies with a larger patient population or pure subgroups are expected in the future.

• 한국지반공학회논문집
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• 제20권5호
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• pp.37-48
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• 2004

본 연구에서는 사질토의 취성적 응력-변형률 관계와 전단시 체적팽창을 고려할 수 있는 구성모델에 대한 연구를 수행하였다. 제안된 모델은 일반등방경화규칙에 의거한 비등방 경화규칙을 적용하였으며, 미소변형에서 대변형에 이르는 전체변형률 영역의 거동을 모델할 수 있도록 적합한 경화함수를 이용하였다. 항복면의 형태는 응력공간에서 원통형으로 나타나는 단순한 형태로 실용적으로 적용하기 편리하도록 하였다. 또한 유동규칙을 단순화하여 소성 체적 변형률을 팽창률을 이용하여 정의하였다. 이로 인하여 사질토에서 나타나는 전단시 팽창을 모델하는 것이 가능하였다. 또한 가상적인 첨두응력비를 정의하여 취성적 응력-변형률 관계를 모델하는 것이 가능하였다. 이 때 제안된 모델의 계수를 체계적으로 결정하기 위하여 실수형 유전자 알고리즘이 적용된 최적화 기법이 적용되었다. 이를 통하여 구성 모델에 필요한 계수를 결정할 수 있었다. 제안된 모델을 검증하기 위하여 풍화토시료에 대한 $K_0$ 압밀 삼축시험을 수행하였다. 이러한 시험결과를 제안된 모델과 비교한 결과 $K_0$ 압밀 시험에서 나타나는 취성적 응력-변형률 관계 및 체적의 팽창과 같은 실제 유효응력 거동을 합리적으로 모델하는 것이 가능하였다.