• 제목/요약/키워드: Genetic enhancement

검색결과 142건 처리시간 0.03초

종묘방류에 따른 넙치, Paralichthys olivaceus 지역집단의 유전학적 구조 (Genetic Variability and Population Structure of Olive Flounder Paralichthys olivaceus from Stocked Areas Using Microsatellite DNA Markers)

  • 정달상;전창영
    • 한국어류학회지
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    • 제20권3호
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    • pp.156-162
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    • 2008
  • 넙치의 자원조성을 위해 인위적으로 생산된 넙치종묘를 방류함에 따라 이들 방류에 의해 그 지역에 서식하고 있는 자연집단에 미치는 영향을 파악하기 위하여 4개 지역 (YD, SC, GJ, WD)에서 어획된 넙치집단의 유전학적 구조와 다양성을 5개의 microsatellite DNA marker를 이용하여 조사하였다. 조사된 지역에서 방류넙치의 혼획율은 20.0~95.8%였다. 넙치집단의 평균 이형접합체(Ho)의 범위는 0.833~0.876이었으며, 지역집단별 평균대립유전자수는 YD 집단 15.0개, SC 집단 17.8개, GJ 집단 14.6개, WD 집단 12.4개였으며, 방류어의 혼획율이 20.0%이었던 SC 집단에서 높게 나타났고 방류어의 혼획율이 95.8%이었던 WD 집단에서 낮게 나타나 방류어의 혼획율이 높을수록 지역집단의 대립유전자의 수가 낮은 경향을 보였다. 집단간 유전학적 거리의 범위는 0.026~0.232로서 WD 집단과 GJ 집단간에서 가장 낮았고, SC-R 집단과 YD-W 집단간에서 가장 멀게 나타났다.

The Effect of γ-Aminobutyric Acid Intake on UVB- Induced Skin Damage in Hairless Mice

  • Hairu Zhao;Bomi Park;Min-Jung Kim;Seok-Hyun Hwang;Tae-Jong Kim;Seung-Un Kim;Iksun Kwon;Jae Sung Hwang
    • Biomolecules & Therapeutics
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    • 제31권6호
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    • pp.640-647
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    • 2023
  • The skin, the largest organ in the body, undergoes age-related changes influenced by both intrinsic and extrinsic factors. The primary external factor is photoaging which causes hyperpigmentation, uneven skin surface, deep wrinkles, and markedly enlarged capillaries. In the human dermis, it decreases fibroblast function, resulting in a lack of collagen structure and also decreases keratinocyte function, which compromises the strength of the protective barrier. In this study, we found that treatment with γ-aminobutyric acid (GABA) had no toxicity to skin fibroblasts and GABA enhanced their migration ability, which can accelerate skin wound healing. UVB radiation was found to significantly induce the production of matrix metalloproteinase 1 (MMP-1), but treatment with GABA resulted in the inhibition of MMP-1 production. We also investigated the enhancement of filaggrin and aquaporin 3 in keratinocytes after treatment with GABA, showing that GABA can effectively improve skin moisturization. In vivo experiments showed that oral administration of GABA significantly improved skin wrinkles and epidermal thickness. After the intake of GABA, there was a significant decrease observed in the increase of skin thickness measured by calipers and erythema. Additionally, the decrease in skin moisture and elasticity in hairless mice exposed to UVB radiation was also significantly restored. Overall, this study demonstrates the potential of GABA as functional food material for improving skin aging and moisturizing.

전력계통 안정도 향상을 위한 TCSC 안정화 장치의 GA-퍼지 전 보상기 설계 (Design of GA-Fuzzy Precompensator of TCSC-PSS for Enhancement of Power System Stability)

  • 정문규;왕용필;정형환;이창우;이정필;허동렬
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2004년도 하계학술대회 논문집 A
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    • pp.292-294
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    • 2004
  • In this paper, we design the GA-fuzzy precompensator of a Power System Stabilizer for Thyristor Controlled Series Capacitor(TCSC-PSS) for enhancement of power system stability. Here a fuzzy precompensator is designed as a fuzzy logic-based precompensation approach for TCSC-PSS. This scheme is easily implemented simply by adding a fuzzy precompensator to an existing TCSC-PSS. And we optimize the fuzzy precompensator with a genetic algorithm for complements the demerit such as the difficulty of the component selection of fuzzy controller, namely, scaling factor, membership Auction and control rules. Simulation results show that the proposed control technique is superior to a conventional PSS in dynamic responses over the wide range of operating conditions and is convinced robustness and reliableness in view of structure.

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Feeding the extra billions: strategies to improve crops and enhance future food security

  • Stamm, Petra;Ramamoorthy, Rengasamy;Kumar, Prakash P.
    • Plant Biotechnology Reports
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    • 제5권2호
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    • pp.107-120
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    • 2011
  • The ability to feed an expanding world population poses one of the greatest challenges to mankind in the future. Accompanying the increased demand for food by the expected nine billion inhabitants of Earth in 2050 will be a continual decrease in arable land area, together with a decline in crop yield due to a variety of stresses. For these formidable challenges to be met, future crops should not only by high-yielding, but also stress-tolerant and disease-resistant. In this review, we highlight the importance of genetic engineering as an indispensable tool to generate just such future crops. We briefly discuss strategies and available tools for biotechnological crop improvement and identify selected examples of candidate genes that may be manipulated so that current biological maxima in yield may be surpassed by comfortable margins. Future prospects and the necessity for basic research aimed at identifying novel target genes are also discussed.

Potential Anomaly Separation and Archeological Site Localization Using Genetically Trained Multi-level Cellular Neural Networks

  • Bilgili, Erdem;Goknar, I. Cem;Albora, Ali Muhittin;Ucan, Osman Nuri
    • ETRI Journal
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    • 제27권3호
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    • pp.294-303
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    • 2005
  • In this paper, a supervised algorithm for the evaluation of geophysical sites using a multi-level cellular neural network (ML-CNN) is introduced, developed, and applied to real data. ML-CNN is a stochastic image processing technique based on template optimization using neighborhood relationships of the pixels. The separation/enhancement and border detection performance of the proposed method is evaluated by various interesting real applications. A genetic algorithm is used in the optimization of CNN templates. The first application is concerned with the separation of potential field data of the Dumluca chromite region, which is one of the rich reserves of Turkey; in this context, the classical approach to the gravity anomaly separation method is one of the main problems in geophysics. The other application is the border detection of archeological ruins of the Hittite Empire in Turkey. The Hittite civilization sites located at the Sivas-Altinyayla region of Turkey are among the most important archeological sites in history, one reason among others being that written documentation was first produced by this civilization.

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A Study on Performance Enhancement for Remote Operation of Industrial Equipments

  • Lho, Tae-Jung;Joo, Hyun-Woo;Kang, Dong-Jung;Song, Se-Hoon;Park, Ki-Tae
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2003년도 ICCAS
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    • pp.813-817
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    • 2003
  • By increasing trades between countries, importance of harbors is becoming serious, including our country. When it comes to Container Crane Operation, the most important matter is how many containers are loaded in a truck or a ship by given time. This can be a crucial matter of harbors in taking care of materials. The present harbors' crane uses a wire-rope conveyance materials are transported in the air and have high free-angle of location. The sway can cause the delay of time, wrong position of Trolley and the damage of materials. In this study, we obtain the optimal PID parameters with GA(Genetic Algorithm) and apply those parameters to the PID Controller. In the result of the experimentation, we can see how effectively the PID controller, applied with the optimal parameters obtained by GA, can control the sway angle.

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전 영역 그레이코드 유전자 알고리듬의 효율성 증대에 관한 연구 (A Study on Computational Efficiency Enhancement by Using Full Gray Code Genetic Algorithm)

  • 이원창;성활경
    • 한국정밀공학회지
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    • 제20권10호
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    • pp.169-176
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    • 2003
  • Genetic algorithm (GA), which has a powerful searching ability and is comparatively easy to use and also to apply, is in the spotlight in the field of the optimization for mechanical systems these days. However, it also contains some problems of slow convergence and low efficiency caused by a huge amount of repetitive computation. To improve the processing efficiency of repetitive computation, some papers have proposed paralleled GA these days. There are some cases that mention the use of gray code or suggest using gray code partially in GA to raise its slow convergence. Gray code is an encoding of numbers so that adjacent numbers have a single digit differing by 1. A binary gray code with n digits corresponds to a hamiltonian path on an n-dimensional hypercube (including direction reversals). The term gray code is open used to refer to a reflected code, or more specifically still, the binary reflected gray code. However, according to proposed reports, gray code GA has lower convergence about 10-20% comparing with binary code GA without presenting any results. This study proposes new Full gray code GA (FGGA) applying a gray code throughout all basic operation fields of GA, which has a good data processing ability to improve the slow convergence of binary code GA.

GA를 이용한 4족 보행로봇의 걸음새 자동 생성 및 성능향상 (Automatic Gait Generation for Quadruped Robot Using GA with an Enhancement of Performance)

  • 서기성;최준석;조영완
    • 한국지능시스템학회논문지
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    • 제18권4호
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    • pp.555-561
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    • 2008
  • GA 기반의 4족 보행로봇의 걸음새의 속도와 안정성을 최적화하는 걸음새의 자동 생성 방법을 구현한다. 기존에 사용된 걸음새 파라미터 집합에서 중요 파라미터의 영향을 분석하였고, 이를 통해 효율적인 탐색 방향을 설정하였다. 또한 속도 위주의 기존 연구와는 달리 반 정확도가 수반된 결과를 얻도록 하였다. 제안된 기법의 검증을 위하여 SONY Aibo 4족 보행 로봇에 대해서 ODE 기반의 물리적 특성을 포함한 정교한 시뮬레이션이 가능한 Webots 을 이용하여 실험을 수행하였고, 속도와 안정성 면에서 향상된 결과를 얻었다.

UPFC Device: Optimal Location and Parameter Setting to Reduce Losses in Electric-Power Systems Using a Genetic-algorithm Method

  • Mezaache, Mohamed;Chikhi, Khaled;Fetha, Cherif
    • Transactions on Electrical and Electronic Materials
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    • 제17권1호
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    • pp.1-6
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    • 2016
  • Ensuring the secure operation of power systems has become an important and critical matter during the present time, along with the development of large, complex and load-increasing systems. Security constraints such as the thermal limits of transmission lines and bus-voltage limits must be satisfied under all of a system’s operational conditions. An alternative solution to improve the security of a power system is the employment of Flexible Alternating-Current Transmission Systems (FACTS). FACTS devices can reduce the flows of heavily loaded lines, maintain the bus voltages at desired levels, and improve the stability of a power network. The Unified Power Flow Controller (UPFC) is a versatile FACTS device that can independently or simultaneously control the active power, the reactive power and the bus voltage; however, to achieve such functionality, it is very important to determine the optimal location of the UPFC device, with the appropriate parameter setting, in the power system. In this paper, a genetic algorithm (GA) method is applied to determine the optimal location of the UPFC device in a network for the enhancement of the power-system loadability and the minimization of the active power loss in the transmission line. To verify our approach, simulations were performed on the IEEE 14 Bus, 30 Bus, and 57 Bus test systems. The proposed work was implemented in the MATLAB platform.

Seismic behavior enhancement of frame structure considering parameter sensitivity of self-centering braces

  • Xu, Longhe;Xie, Xingsi;Yan, Xintong;Li, Zhongxian
    • Structural Engineering and Mechanics
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    • 제71권1호
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    • pp.45-56
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    • 2019
  • A modified mechanical model of pre-pressed spring self-centering energy dissipation (PS-SCED) brace is proposed, and the hysteresis band is distinguished by the indication of relevant state variables. The MDOF frame system equipped with the braces is formulated in an incremental form of linear acceleration method. A multi-objective genetic algorithm (GA) based brace parameter optimization method is developed to obtain an optimal solution from the primary design scheme. Parameter sensitivities derived by the direct differentiation method are used to modify the change rate of parameters in the GA operator. A case study is conducted on a steel braced frame to illustrate the effect of brace parameters on node displacements, and validate the feasibility of the modified mechanical model. The optimization results and computational process information are compared among three cases of different strategies of parameter change as well. The accuracy is also verified by the calculation results of finite element model. This work can help the applications of PS-SCED brace optimization related to parameter sensitivity, and fulfill the systematic design procedure of PS-SCED brace-structure system with completed and prospective consequences.