• Journal of the Korean Society of Hazard Mitigation
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• v.9 no.6
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• pp.31-39
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• 2009

This study has found that there is a reverse phase with interdecadal variation in temporal variations of tropical cyclone (TC) genesis frequency (TCGF) between Northwest sector and Southeast sector, based on climatological mean tropical cyclone genesis location over the western North Pacific. The TCGF in the Northwest sector has been increased since the mid 1980s (1986-2005), while TCGF in the Southeast sector was higher until the early 1970s (1951-1970). The analysis of a difference between 1986-2005 and 1951-1970 showed results as follows: i) Through the analysis of vertical wind shear (VWS) and sea surface temperature (SST), less VWS and higher SST in the former (latter) period was located in the Northwest (Southeast) sector. ii) In the analysis of TC passage frequency (TCPF), TCs occurred in the Northwest sector frequently passed from east sea of the Philippines, through East China Sea, to Korea and Japan in the latter period, while TCs in the former period frequently has a lot of influences on South China Sea (SCS). In the case of TCs occurred in the Southeast sector, TCs in the west (east), based on $150^{\circ}E$ had a high passage frequency in the latter (former) period. In particular, TCs during the latter period frequently moved toward from the east sea of the Philippines to SCS and southern China. iii) This difference of TCPF between the two periods was characterized by 500 hPa anomalous pressure pattern. Particularly, anomalous cyclonic circulation strengthened over the East Asian continent caused anomalous southerlies along the East Asian coast line from the east sea of the Philippines to be predominate. These anomalous winds served as steering flows that TC can easily move toward same regions.

• Journal of the Korean earth science society
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• v.37 no.6
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• pp.359-372
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• 2016

The time-series of Walker circulation index (WCI) in this study shows the strengthening of the Walker circulation in recent years. To further understand the large-scale features related to the WCI strengthening, a difference between the averaged meteorological variables in two time periods 1999-2013 and 1984-1998 is analyzed. The difference in 850 hPa stream flows between the two periods shows that the anomalous easterlies (anomalous trade wind) are dominant due to the strengthening of anomalous anticyclonic circulations at the subtropical Pacific of both hemispheres. The difference between the averaged zonal atmospheric circulations over $5^oS-5^oN$ in the two periods confirms that upward flows are strengthened at the tropical western Pacific and downward flows are strengthened at the tropical central and eastern Pacific in recent years. It matches the WCI strengthening in recent years. The time-series of tropical cyclone (TC) genesis frequency from July to September shows that a mean TC genesis frequency from 1999-2013 decreases compared to that of the time period 1984-1998. The monsoon trough in the period 1984-1998 was located in the further east direction and stronger than that in the period 1999-2013. TCs in the recent period that are generated in further west than TCs in the past period moved from the west. Thus, the TC intensity along the coasts in East Asia becomes weaker in recent period. The intensification of Walker circulation in recent years is related to the weaker TC intensity in East Asia through strengthened anomalous anticyclones at the subtropical western Pacific.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.11
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• pp.4813-4818
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• 2016

Objective: The objective of the study was to determine the Knowledge, Attitude and Practice of chewing gutka,areca nut, snuff and tobacco smoking among the young population in the Northern India Population between the age of 15 to 22 years. Methods: The study was approved by the ethical committee. A total of 10 school and colleges located in the rural and urban areas was selected. A total of 1500 young individuals aged between 15 to 22 years were selected. A self-administered questionnaire was designed comprised of 14 closed ended questions about Knowledge, Attitude and Practice towards consumption of areca nut, gutka and tobacco smoking that were filled by the participants. Descriptive statistics were obtained and mean, standard deviation, frequency and percentages were calculated. Data was analyzed by using SPSS. Result: A total of 1050 out of 1500 students responded to the questionnaire. A total of 227 subjects agreed that they are consuming the tobacco. Out of this, 196 (86.34%) were boys and 31 (13.65%) were girls who agreed in consumption of tobacco product. Out of 196, 150 boys (76.5%) practices the habit of smoking 1 -5 times a day and 46 (23.4% ) practice the habit of chewing areca nut and gutkha 1 - 5 times a day. Out of 31 girls, 25 girls (80.6%) practices the habit of smoking 1 -5 times a day and 6 (19.4%) practice the habit of chewing areca nut and gutkha 1 - 5 times a day. Out of 740 subjects, 530 were boys and 210 girls have full knowledge of deleterious long term effects of tobacco consumption. Conclusion:The present study concluded that young population of North India lack Knowledge, Attitude and Practice regarding consumption of areca nut, gutka and tobacco smoking. Here is an urgent need to take effective steps, especially on launching community awareness programs for the school children and public to educate them about the consequences of tobacco use, and on assessing their effectiveness in curbing the problem.

• Journal of Korea Water Resources Association
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• v.47 no.4
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• pp.385-396
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• 2014

Lately, more frequent typhoons cause extensive flood and wind damage throughout the summer season. In this respect, this study aims to develop a probabilistic clustering model that uses both typhoon genesis location and trajectories. The proposed model was applied to the 197 typhoon events that made landfall in the Korean peninsula from 1951 to 2012. We evaluate the performance of the proposed clustering model through a simulation study based on synthetic typhoon trajectories. The seven distinguished clusters for typhoons affecting Korean peninsula were identified. It was found that most of typhoon genesis originated from a remote position ($10^{\circ}{\sim}20^{\circ}N$, $120^{\circ}{\sim}150^{\circ}E$) near the Equator. Cluster, type B can be regarded as a major track due to the fact that its frequency is approximately about 25.4% out of 197 events and its direct association with strong positive rainfall anomalies.

• Korean Journal of Biological Psychiatry
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• v.20 no.4
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• pp.166-178
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• 2013

Objectives Alteration of epigenetic effects of testosterone during early development was suggested as an ancillary mechanism for the genesis of schizophrenia. EEG coherence was thought to be a marker for cerebral laterality of which important determinant was testosterone during early development. We studied sex-related differences of EEG coherences between patients with schizophrenia and controls to examine the sex effects in the genesis of schizophrenia. Methods EEG was recorded in 35 patients with schizophrenia and 46 healthy controls in the eyes closed resting state. Pair-wise EEG coherences were calculated over delta, theta, alpha, beta and gamma frequency bands. To examine the differences of EEG coherence according to sex in each group, ANCOVA was performed using Statistical Analysis system (SAS, Ver 9.3) and R (Ver 2.15.2). Results Healthy control males showed more increased right intrahemispheric coherences than healthy control females in delta, theta, alpha and beta frequency bands. In patients with schizophrenia, this male dominant pattern in right intrahemispheric coherences was attenuated especially in alpha and beta bands. Healthy control females showed more increased interhemispheric coherences than healthy control males in delta, theta, beta and gamma frequency bands. In patients with schizophrenia, these female dominant patterns in interhemispheric coherences were attenuated especially in delta, theta, and beta bands, which were commonly observed in frontal to central areas. Conclusion Sex differences in resting EEG coherences were attenuated in schizophrenia patients. These results imply that sex-related aberrant cerebral lateralization might exist in patients with schizophrenia, which are partly due to sex hormones via epigenetic mechanisms.

• Atmosphere
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• v.18 no.4
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• pp.279-286
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• 2008

In the tropical western Pacific (especially, west of 135oE, including South China Sea and the Philippines), during boreal summer, it was found that a strong correlation exists between the tropical cyclone activity and the drought conditions in Korea. During the summer drought, firstly, there were strong ascending flows over the tropical western Pacific with more tropical cyclone genesis, and to compensate for this, descending flows develop in the mid-latitudes, thereby causing drought; in other words, a secondary circulation is formed between the tropical western Pacific and mid-latitudes of East Asia. Secondly, the developments of both the subtropical western Pacific high and the Manchurian low are suppressed. As a result, both the land-sea pressure gradient and the southerly flow from low-latitudes to Korean area are also weakened, which reduces approaches of tropical cyclones to this area despite the high frequency of their geneses.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.4
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• pp.2521-2523
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• 2013

Background: Papillary thyroid cancer or papillary thyroid carcinoma (PTC) is the most common thyroid cancer. The fact that it occasionally occurs in women aged 30-40 years old suggests that genetic alterations are involved its genesis. Recently, activator mutations in BRAF gene have been relatively frequently discovered. Materials and Methods: In this study, we tested 63 DNA samples from PTC patients to identify the V600E mutation frequency in the Ahvaz population. DNA was isolated from formalin fixed paraffin-embedded (FFPE) PTC tumor tissues. Genotyping was performed by PCR-RFLP and confirmed by direct DNA sequencing of a subset of PCR products. PCR-RFLP data were reported as genotype frequencies and percentages. Results: Forty nine out of 63 patients (77.8%) had a mutated heterozygote form while 14 (22.2%) showed normal genotype but none demonstrated a mutant homozygote genotype. The frequency of V600E mutation was significantly high in PTC patients. Conclusions: These findings support involvement of V600E mutations in PTC occurrence in Iran. Assessment of correlations between BRAF V600E mutations and papillary thyroid cancer progression needs to be performed.

• Journal of the Korean earth science society
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• v.34 no.3
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• pp.224-234
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• 2013

This study examined a strong positive correlation between the North Atlantic Oscillation (NAO) index during June and the total tropical cyclone (TC) genesis frequency in the western North Pacific during July and August. To investigate a possible cause for this relationship, the mean difference between the highest positive NAO years and the lowest negative NAO years was analyzed by dividing into when the El Ni$\tilde{n}$o and La Ni$\tilde{n}$a years were included and when the El Ni$\tilde{n}$o and La Ni$\tilde{n}$a years were not included. When the El Ni$\tilde{n}$o and La Ni$\tilde{n}$a years were included, for the positive NAO years, the TCs mostly occurred in the northwestern region of tropical and subtropical western Pacific, and showed a pattern that migrate from the sea northeast of the Philippines, pass the East China Sea, and move toward the mid-latitudes of East Asia. In contrast, for the negative NAO years, the TCs mostly occurred in the southeastern region of tropical and subtropical western Pacific, and showed a pattern that migrate westward from the sea southeast of the Philippines, pass the South China Sea, and move toward the southern coast of China and Indochinese peninsula. These two different TC migration patterns affect the recurving location of TC, and for the positive NAO years, the recurving of TC was averagely found to take place in the further northeast. In addition, the migration patterns also affect the TC intensity, and the TCs of positive NAO years had stronger intensity than the TCs of negative NAO years as sufficient energy can be absorbed from the ocean while moving north in the mid-latitudes of East Asia. The TCs of negative NAO years showed weak intensity as they get weaken or disappear shortly while landing on the southern coast of China and the Indochinese peninsula. On the other hand, the above result of analysis is also similarly observed when the El Ni$\tilde{n}$o and La Ni$\tilde{n}$a years were not included.

• Journal of the Korean earth science society
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• v.27 no.6
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• pp.653-658
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• 2006

The seasonal predictability of typhoon activity over the western North Pacific is investigated using an atmospheric general circulation model GCPS. A ten-member ensemble with different initial conditions is integrated for five months using observed sea surface temperature data for each year from 1979 to 2003. It is shown that the monthly variation of occurrence frequency of simulated tropical storms and the distribution of tropical storm genesis location are similar to those of observed tropical storms, but the model is unable to reliably predict the interannual variation of the occurrence frequency of tropical storms. This is largely because the observed relationship between tropical storm occurrence frequency and ENSO is different from the simulated one. Unlike the observation, in which the tropical storm occurrence frequency has no relation to ENSO, the model has a tendency to generate more (less) tropical storms than normal during El Nino (La Nina). On the other hand, the interannual variation of the mean longitude of tropical storms that shows a close connection with ENSO in both observations and simulations is simulated similar to the observation.

• The Korean Journal of Physiology
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• v.20 no.1
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• pp.9-15
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• 1986

The effect of dopamine on the propagation and the frequency electrical activities (slow wave) of the stomach was studied in isolated stomach muscle strips of 145 cats, The gastric slow wave monopolarly recorded by four capillary electrodes (Ag-AgCl) in Krebs-Ringer solution $(ph\;7.4,\;temperature\;36{\pm}0.5^{\circ}C)$ bubbled with 5% $CO_2$ in $O_2$. Dopamine caused concentration-dependent changes of direction of slow wave propagation with decline in development of irregular propagation by domperidone pretreatment. Dopamine also increased the variation of slow wave frequency concentration-dependently. The variation of slow wave frequency induced by dopamine was significantly inhibited by pretreatment with domperidone and phentolamine but not with propranolol, hexamethonium and tetrodotoxin. It is therefore suggested that dopamine plays a role in the genesis of gastric electrical abnormality acting on dopamine receptors and partly on ${\alpha}-adrenergic$ receptors in cats.