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Chromosome Configurations of Human Oocytes Matured in vitro following Cryopreservation at the Germinal Vesicle Stage (인간 미성숙난자의 동결.융해후 체외 배양된 난자에 대한 염색체 분석)

  • Park, S.E.;Chung, C.J.;Son, W.Y.;Chung, H.M.;Lee, S.H.;Lee, W.S.;Ko, J.J.;Yoon, T.K.;Cha, K.Y.
    • Clinical and Experimental Reproductive Medicine
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    • v.24 no.2
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    • pp.253-259
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    • 1997

  • Objective: To investigate effects of cryoprotectant and cryopreservation on the chromosome of the human immature oocytes. Design: Intact cumulus-enclosed immature oocytes were collected from unstimulated ovaries and divided into three groups, such as no treatment as control (group 1), only 1,2-propanediol (PROH)-treated (group 2), and cryopreserved oocytes (group 3). Oocytes in group 1, 2, and survived oocytes after cryopreservation in group 3 were cultured for 48 hours. Setting: Infertility Medical Center at the CHA General Hospital, Seoul, Korea. Patients: Oocytes were obtained from Patients undergoing gynecological surgery. Main Outcome Measures: Maturation rate, abnormality in chromosomes by fluorescence in situ hybridization (FISH). Results: There was no effect of PROH only treatment on the chromosomal abnormalities in group 2 compared to control oocytes (41.4% and 31.8%, respectively). Whereas significantly increased abnormalities in chromosome (77.8%) were found in group 3. Conclusions: Human oocytes matured in vitro after cryopreservation at the germinal vesicle (GV) stage showed increased incidence of chromosomal abnormalities. These abnormalities may impair the capacity for further development of the embryos derived from frozen-thawed oocytes.

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A SURVEY OF DENTAL TREATMENT UNDER OUTPATIENT GENERAL ANESTHESIA AT CHONBUK NATIONAL UNIVERSITY DENTAL HOSPITAL BETWEEN 2014~2017 (2014년부터 2017년까지 전북대학교 치과병원에서 외래 전신마취 하에 치과치료를 받은 증례에 관한 연구)

  • Ahn, Na Hyun;Lee, Daewoo;Kim, Jaegon;Yang, Yeon Mi
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.15 no.1
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    • pp.1-6
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    • 2019

  • There are increasing number of patients having dental treatment under outpatient general anesthesia. There were researches that studied patients treated under outpatient general anesthesia in Chonbuk National University Dental hospital between 2005~2013. However, there has been an absence of research since 2013. Therefore, the aim of this research is to study cases regarding outpatient general anesthesia visiting Chonbuk National University hospital between 2014~2017 and analyze the trends of these patients. The medical records of 409 cases from January, 2014 to December, 2017 were reviewed. From the patients' charts, data on sex, residence, visiting dates, disability status, and types and number of treatments was collected and investigated. The number of cases has increased from 86 in 2014 to 140 in 2017. Among 409 cases, 275 cases(67.2%) had disabilities, with mental disabilities consisting most of the disabilities. 192 cases were aged under 20 years old mostly with no disabilities, 142 cases were 20~39 years old mostly with mental disabilities, and 75 cases were 40 years old or more mostly with physical disabilities. The conservative treatment was performed most frequently in both disabled and non-disabled patient groups. There was an increasing trend in the number of patients treated under outpatient general anesthesia, and more than half were disabled patients. In order to meet this demand, Chonbuk National University Dental Hospital increased the number of general anesthesia pracrice. To follow this trends, the implementation of safe outpatient general anesthesia system and cooperation among teams is needed to improve the quality of treatments.

  • https://doi.org/10.12655/KADH.2019.15.1.1 인용 PDF KSCI HTML

MIXED QUASI VARIATIONAL INEQUALITIES INVOLVING FOUR NONLINEAR OPERATORS

  • Pervez, Amjad;Khan, Awais Gul;Noor, Muhammad Aslam;Noor, Khalida Inayat
    • Honam Mathematical Journal
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    • v.42 no.1
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    • pp.17-35
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    • 2020

  • In this paper we introduce and consider a new class of variational inequalities with four operators. This class is called the extended general mixed quasi variational inequality. We show that the extended general mixed quasi variational inequality is equivalent to the fixed point problem. We use this alternative equivalent formulation to discuss the existence of a solution of extended general mixed quasi variational inequality and also develop several iterative methods for solving extended general mixed quasi variational inequality and its variant forms. We consider the convergence analysis of the proposed iterative methods under appropriate conditions. We also introduce a new class of resolvent equation, which is called the extended general implicit resolvent equation and establish an equivalent relation between the extended general implicit resolvent equation and the extended general mixed quasi variational inequality. Some special cases are also discussed.

  • https://doi.org/10.5831/HMJ.2020.42.1.17 인용 PDF KSCI