• 종양간호연구
• /
• 제12권1호
• /
• pp.52-60
• /
• 2012

Purpose: This study is to determine knowledge about early detection and risk perception of cancer according to taking cancer screening tests in the general population. Methods: The participants were 151 people aged 40 years or older. A questionnaire consisted of knowledge about early detection (warning signs, cancer screening methods, general knowledge for early detection), cancer risk perception and history of cancer screening during past 2 years. Results: The percentages of correct answers were 64.7% in knowledge about warning signs, 73.7% in knowledge of cancer screening tests and 80.1% in general knowledge for early detection. Participants had the highest knowledge about screening methods for stomach cancer and the lowest for liver and colon cancer. The level of risk perception was medium. The participants who participated in cancer screening showed lower risk perception than those who did not. There was no significant relationship between knowledge and performance of cancer screening. The primary reason for not participating in cancer screening was patient's perception of their own health. Conclusion: These results suggest that cancer risk perception can affect the performance of cancer screening and we need to study how to handle this problem. Additionally screening programs should focus on liver cancer and colon cancer.

• 대한안전경영과학회지
• /
• 제17권4호
• /
• pp.105-112
• /
• 2015

Sawmilling industry remained a high risk with the average 4.73% of industrial accidents in 2010-2012 that was eight times that of general manufacturing. Sawmilling industry had 200 industrial accidents victim in average. Manufacturing process in sawmill industry contained dangerous machinery such as conveyors, roller, saw ( band saw, circular saw) etc. It may be effective to figure out the type of industrial accidents occurred in the past and extend risk assessment which can predict hazard such as near miss when implementing exposure or potential dangers in sawmill industry. This study conducted research on the actual condition on the place of industrial accident occurrence, detailed work and contact object when injured, and injured part targeting 643 businesses which had industrial accidents in 2010-2012. As the results, RPN of general sawmill industry was the highest 'ganglip saw' with 36,157. RPN of the following order were 'moving truck' with 25,454, 'special machining operations' with 22,283. Also, probability of general sawmill industry was a lots within 1 year, while risk appeared a lots within 5 years. So, risk assessment shall be needed to emphasis on accident prevention of sawmill industry. And additional work will be needed on the risk assessment in hazard prevention work of supervisors.

• 한국안전학회지
• /
• 제28권6호
• /
• pp.90-96
• /
• 2013

Since the last 50 years, the terminology 'risk' has been widely used in general and industrial applications, with different meanings. The different definitions of risk can lead to the different risk assessments and risk management process elements, and the misunderstandings. For the reasons, the ISO(International Standard Organization) has recently defined a new risk concept through the publication of IS0 31000:2009. Although the new concept of risk was globally accepted, it seem to be argued in its definition debate. Thus, this paper reviews the definition and meaning of the concept of risk in terms of risk origin, general and industrial applications, related domestic laws and risk management standards published to improve an understanding of risk concept.

• Environmental Analysis Health and Toxicology
• /
• 제14권4호
• /
• pp.175-187
• /
• 1999

To investigate the risk perception of environmental issues, two consequtive surveys were conducted to environmental professionals using a standardized questionnaire from September to October in 1999. The number of subjects were 72 for the first survey and 68 for the second one. The questionnaire was consisted of items such as the degree of environmental pollution in Korea, risk perception of some issues on human health and ecosystem, and seriousness of the problems in the real situation in Korea. For the degree of environmental pollution in Korea, the average risk rating in the second test (7.4 point) was significantly higher than that in the first test (7.2 point). The risk perception on the general human health and ecosystem, and the seriousness in Korea situation were analyzed in the order of ′air pollution′, ′water pollution′,′soil contamination′,′waste′,′toxic chemical pollutants′,′food contamination′,′ocean contamination′, ′odor pollution′, and ′noise pollution′. Also ′toxic chemical pollutants′ problem was perceived to be the highest risk on general human health or ecosystem, and on present situation in Korea. ′Automotive vehicle exhaust′ problem was perceived to be the most severe environmental problems among specific 30 items. ′Industrial source air pollution′,′toxic air pollutants′, and ′domestic and industrial source pollutants to surface water′ were relatively severe environmental problems comparing to other problems. The pollution issues were classified into four categories by two aspects of perception; risk in general setting and seriousness in Korea situation. If the issues were highly serious in Korea and low risk perception in general setting then it is named "the Korea-specific group". Those that were all high score in two aspects, named "the Common group". Those that were all low in two aspects, named "the Nonsignificant group". And the issues were high risk perception in general setting and low seriousness in Korean situation, named "the Latent group".

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권7호
• /
• pp.4239-4242
• /
• 2013

It is reported that the expression level of MLL3 in gastric cancer tissue highly correlates with tumor progression. However, whether MLL3 genetic variants are associated with the risk of gastric cancer remains unclear. In this study, we conducted a genotyping analysis for MLL3 in 314 cases of gastric cancer and 322 controls from the Chinese Han population. 4 SNPs (rs6943984, rs4725443, rs3800836, rs6464211) were selected for the present analysis. We found 2 SNPs (rs6943984, rs4725443) of MLL3 gene were significantly associated with the risk of gastric cancer : the rs6943984 with the minor allele A and rs4725443 with the minor allele C revealed strong associations with increased gastric cancer risk [P < 0.001, OR=1.97, 95% CI=1.48~2.64 and P <0.001, OR=2.23, 95% CI=1.54~3.24]. Haplotype analysis of the four SNPs showed that haplotype A-T-A-C, G-T-G-C, and G-C-A-C increased the risk of gastric cancer (P <0.001, P=0.18, and P<0.001, respectively), while haplotype G-T-A-C significantly reduced the risk of gastric cancer (P <0.001). We concluded that MLL3 variants are significantly associated with gastric cancer risk. Our results for the first time provided new insight into susceptibility factors of MLL3 gene variants in carcinogenesis of gastric cancer of the Chinese Han population.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권7호
• /
• pp.3325-3328
• /
• 2012

Aim: To evaluate the association of glutathione S-transferases gene polymorphisms with the risk of gastric cancer, with reference to smoking and Helicobacter pylori infection. Methods: We conducted a 1:1 matched case-control study with 410 gastric cancer cases and 410 cancer-free controls. Polymorphisms of GSTM1, GSTT1 and GSTP1 were determined using PCR-CTPP. Results: The GSTM1 and GSTT1 null genotypes were significantly associated with the risk of gastric cancer after adjusting for potential confounding factors (OR=1.68, 95% CI=1.32-2.23 for null GSTM1, OR=1.73; 95% CI=1.24-2.13 for null GSTT1). The combination of null GSTM1 and null GSTT1 conferred an elevated risk (OR=2.54, 95% CI=1.55-3.39). However, no association was found for GSTP1 polymorphism The smoking modified the association of GSTM1 and GSTT1 null genotypes with the risk of gastric cancer. Conclusion: GSTM1 and GSTT1 null genotypes are associated with increased risk of gastric cancer, and smoking modifies the association.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권8호
• /
• pp.3601-3604
• /
• 2012

Purpose: Numerous studies have evaluated the association between XRCC1 Arg399Gln gene polymorphism and hepatocellular carcinoma risk in the Chinese Han population. However, the results have been inconsistent. We therefore here examined whether the XRCC1 Arg399Gln gene polymorphism confers hepatocellular carcinoma risk by conducting a meta-analysis. Methods: PubMed, Google scholar and China National Knowledge Infrastructure databases were searched for eligible articles in English and Chinese that were published before April 2012. Results: 6 studies involving 1,246 patients with hepatocellular carcinoma and 1,953 controls were included. The association between XRCC1 Arg399Gln gene polymorphism and hepatocellular carcinoma in the Chinese Han population was significant under GG vs AA (OR = 1.48, 95% CI = 1.13 to 1.94). Limiting the analysis to the studies with controls in the Hardy-Weinberg equilibrium, the results were persistent and robust. Conclusions: In the Chinese Han population, the XRCC1 Arg399Gln gene polymorphism is associated with an increased hepatocellular carcinoma risk.

• 한국건설관리학회논문집
• /
• 제6권5호
• /
• pp.177-185
• /
• 2005

건설공사의 불확실성은 빈번히 클레임에 노출된다. 대부분의 경우 이러한 클레임에 대한 기본적인 해석은 공사계약서를 기준으로 하게 된다. 이러한 계약서 작성시의 문제는 발주자나 시공자가 부담하여야 하는 계약적 위험(risk)이 어떻게 규정되어 있어야 합리적인 수준인가를 판단하는 것인데 이러한 판단을 위해서는 FIDIC 계약조건과 같이 국제적으로 합리성을 인정받는 표준계약조건을 참고하는 것이 합리적이라 하겠다. 이에 본 연구는 FIDIC 계약조건을 기준으로 국내 공공공사에서 일반적으로 사용하는 공사계약일반조건에 내재되어 있는 불공정, 불합리 조항을 분석하여 세계적 수준에 맞는 공사계약조건을 제시하고자 위험관리의 관점에서 공사 계약조건을 분석하고, 여기서 도출되는 위험요인을 검증하며, 이에 대한 대응방안을 모색함으로써 공사계약일반조건의 위험요인 감소방안을 제시하고자 한다.

• 한국독성학회:학술대회논문집
• /
• 한국독성학회 2005년도 춘계 국제심포지엄 및 학술대회
• /
• pp.207-207
• /
• 2005

• 한국항해항만학회지
• /
• 제35권1호
• /
• pp.23-30
• /
• 2011

본 논문은, 국적일반화물선 공식안전성평가(Formal Safety Assessment, 이하 FSA) 연구의 1, 2 단계에 해당하는 위험요소 식별(Hazard identification) 및 식별된 사고 시나리오에 대한 위험도 분석(Risk analysis) 결과를 소개한 "국적일반화물선 초기안전성평가 연구(1)"에 이어 FSA 연구의 3, 4 그리고 5단계를 수행한 내용으로, 국적일반화물선의 운용 중 발생 가능한 위험을 저감할 수 있는 위험도제어방안들(Risk Control Options)을 식별하는 단계(Step 3)와 식별된 위험도제어방안들 중 전문가 의견수렴을 통하여 선별된 위험도제어방안들을 대상으로 한 비용-효과 평가 단계(Step 4: Cost-Benefit Assessment) 그리고 비용-효과 평가의 결과를 정리하여 국적일반화물선의 안전성 제고를 위한 구체적인 방안을 제안하는 단계(Step 5: Recommendation for Decision Making)의 결과를 소개하였다.