• Communications for Statistical Applications and Methods
• /
• 제29권3호
• /
• pp.287-299
• /
• 2022

In radiation epidemiology, the excess relative risk (ERR) model is used to determine the dose-response relationship. In general, the dose-response relationship for the ERR model is assumed to be linear, linear-quadratic, linear-threshold, quadratic, and so on. However, since none of these functions dominate other functions for expressing the dose-response relationship, a Bayesian semiparametric method using splines has recently been proposed. Thus, we improve the Bayesian semiparametric method for the selection of the tuning parameters for splines as the number and location of knots using a Bayesian knot selection method. Equally spaced knots cannot capture the characteristic of radiation exposed dose distribution which is highly skewed in general. Therefore, we propose a nonparametric Bayesian knot selection method based on a Dirichlet process mixture model. Inference of the spline coefficients after obtaining the number and location of knots is performed in the Bayesian framework. We apply this approach to the life span study cohort data from the radiation effects research foundation in Japan, and the results illustrate that the proposed method provides competitive curve estimates for the dose-response curve and relatively stable credible intervals for the curve.

• 한국추진공학회:학술대회논문집
• /
• 한국추진공학회 1996년도 제7회 학술강연회논문집
• /
• pp.119-133
• /
• 1996

A wave equation and a comprehensive linear combustion model are developed for ramjet and afterburner combustion instability predictions. Modal analysis is used to develop general results for frequencies and damping factors and examples of their applications are given.

• 한국정밀공학회지
• /
• 제18권4호
• /
• pp.64-71
• /
• 2001

In general, precise linear actuators using piezoelectric element are driven by friction force. Exact understanding of friction plays an important role in analysis and control of a motor. In this research, we designed a precise linear actuator using piezoelectric elements and observed its dynamic characteristics. By varying phase angle difference and amplitudes of the sinusoidal waves that are driving inputs, we can know that it is possible to control moving direction and distance of the slider. As preload is increased, its moving distance is decreased. And also, we have modeled a precise linear actuator using stick slip friction models such as classical, Karnopp. and reset integrator. Finally, by comparing the results of simulation and experiment, it was verified that the model is well designed.

• 한국경영과학회지
• /
• 제25권3호
• /
• pp.91-107
• /
• 2000

The linear programming model is a special form of useful knowledge that is embedded in a database. Since formulating models from scratch requires knowledge-intensive efforts, knowledge-based formulation support systems have been proposed in the Decision Support Systems area. However, they rely on the assumption that sufficient domain knowledge should already be captured as a specific knowledge representation form. Hence, the purpose of this paper is to propose a methodology that finds useful knowledge on building linear programming models from a database. The methodology consists of two parts. The first part is to find s first-cut model based on a data dictionary. To do so, we applied the General Problem Solver(GPS) algorithm. The second part is to discover a second-cut model by applying neural network technique. An illustrative example is described to show the feasibility of the proposed methodology.

• 산업경영시스템학회지
• /
• 제38권1호
• /
• pp.118-123
• /
• 2015

There have been various studies on measurements of flood risk and forecasting models. For river and dam region, PDF and FVI has been proposed for measurement of flood risk and regression models have been applied for forecasting model. For Bo region unlikely river or dam region, flood risk would unexpectedly increase due to outgoing water to keep water amount under the designated risk level even the drain system could hardly manage the water amount. GFI and general linear model was proposed for flood risk measurement and forecasting model. In this paper, FVI with the consideration of duration on GFI was proposed for flood risk measurement at Bo region. General linear model was applied to the empirical data from Bo region of Nadong river to derive the forecasting model of FVI at three different values of Base High Level, 2m, 2.5m and 3m. The significant predictor variables on the target variable, FVI were as follows: ground water level based on sea level with negative effect, difference between ground altitude of ground water and river level with negative effect, and difference between ground water level and river level after Bo water being filled with positive sign for quantitative variables. And for qualitative variable, effective soil depth and ground soil type were significant for FVI.

• Journal of the Korean Data and Information Science Society
• /
• 제27권5호
• /
• pp.1215-1224
• /
• 2016

고해상도 격자 단위 기후정보는 농업, 관광학, 생태학, 질병학 등 다양한 분야의 현상을 설명하는 중요 요인이다. 고해상도 기후정보는 동적 모형과 통계적 모형을 통해 얻을 수 있다. 통계적 모형은 동적 모형에 비해 계산 시간이 저렴하여 시공간 해상도가 높은 기후자료 생성에 주로 이용한다. 본 연구에서는 2003년부터 2012년까지 1월에 관측된 일 평균기온자료를 토대로 통계적 모형의 일 평균 기온을 생성하였다. 통계적 모형으로 선형모형을 기반으로한 일반선형모형, 일반화가법모형, 공간선형모형, 베이지안공간선형모형을 고려하였다. 예측성능평가를 위해 60개소의 지상관측소에서 관측된 일 평균기온을 모형적합 자료로 사용하여 352개소의 자동기상관측의 일 평균기온을 검증하였다. 평균제곱오차와 상관계수를 보면 베이지안공간모형의 예측성능이 다른 모형에 비해 상대적으로 우수하였다. 최종적으로 $1km{\times}1km$ 격자 단위 일 평균기온 지도를 생성하였다.

• Molecules and Cells
• /
• 제45권7호
• /
• pp.444-453
• /
• 2022

Multivalent macromolecular interactions underlie dynamic regulation of diverse biological processes in ever-changing cellular states. These interactions often involve binding of multiple proteins to a linear lattice including intrinsically disordered proteins and the chromosomal DNA with many repeating recognition motifs. Quantitative understanding of such multivalent interactions on a linear lattice is crucial for exploring their unique regulatory potentials in the cellular processes. In this review, the distinctive molecular features of the linear lattice system are first discussed with a particular focus on the overlapping nature of potential protein binding sites within a lattice. Then, we introduce two general quantitative frameworks, combinatorial and conditional probability models, dealing with the overlap problem and relating the binding parameters to the experimentally measurable properties of the linear lattice-protein interactions. To this end, we present two specific examples where the quantitative models have been applied and further extended to provide biological insights into specific cellular processes. In the first case, the conditional probability model was extended to highlight the significant impact of nonspecific binding of transcription factors to the chromosomal DNA on gene-specific transcriptional activities. The second case presents the recently developed combinatorial models to unravel the complex organization of target protein binding sites within an intrinsically disordered region (IDR) of a nucleoporin. In particular, these models have suggested a unique function of IDRs as a molecular switch coupling distinct cellular processes. The quantitative models reviewed here are envisioned to further advance for dissection and functional studies of more complex systems including phase-separated biomolecular condensates.

• 한국지구과학회지
• /
• 제28권2호
• /
• pp.214-226
• /
• 2007

강수는 다양한 대기 변수들의 영향으로 나타나기 때문에 비선형성이 매우 강하다. 따라서 역학 모형을 통해 예측된 강수의 보정은 비선형 모형인 인공 신경망 등을 통해 가능할 것이지만, 인공 신경망의 경우 초기 가중치 선택, 지역 최소화 문제, 뉴런의 수 결정 등의 문제로 인한 한계가 있다. 그러므로 본 연구에서는 가장 보편적으로 사용되는 다중 선형 회귀 모형을 이용하여 CGCM에 의해 모사된 강수를 보정하였으며, 예측성을 살펴보았다. 이를 위하여 우선 PNU/CME 접합 대순환 모형(Coupled General Circulation model, CGCM)(박혜선과 안중배, 2004)을 이용하여 1979년부터 2005년까지 매해 4월부터 8월까지 5개월간 앙상블 적분을 하였다. 적분 결과 중 한반도를 포함한 동북아시아 지역$(110^{\circ}E-145^{\circ}E,\;25^{\circ}N-55^{\circ}N)$의 여름철인 6월(리드 2), 7월(리드 3), 8월(리드 4) 및 여름철 평균인 JJA(from June to August) 기간의 PNU/CME CGCM에 의해 모사된 강수를 보정하기 위해 다중 선형 회귀(Multiple Linear Regression, MLR)를 이용하였다. PNU/CME 접합 대순환 모형의 결과 중 강수, 500 hPa 연직 속도, 200 hPa 발산장, 지상 기온 등의 예측 인자와 관측 강수와의 선형적인 관계를 이용하여 MLR 모형을 구축하였다. 그리고 교차 검증(cross- validation)을 수행하여 PNU/CME 접합 대순환 모형의 결과와 교차 검증 결과를 비교하였다. 상관계수, 적중률 (hit rate), 오보율(false alarm rate) 그리고 Heidke 기술 점수(Heidke skill score) 등을 살펴본 바, 보정하지 않은 모형의 결과에 비해 MLR 모형을 이용하여 보정한 결과의 강수에 대한 예측성이 뛰어난 것을 알 수 있었다.

• Structural Engineering and Mechanics
• /
• 제54권3호
• /
• pp.579-595
• /
• 2015

A general geometrically non-linear model for lateral-torsional buckling of thick and thin-walled FGM box beams is presented. In this model primary and secondary torsional warping and shear effects are taken into account. The coupled equilibrium equations obtained from Galerkin's method are derived and the corresponding tangent matrix is used to compute the critical moments. General expression is derived for the lateral-torsional buckling load of unshearable FGM beams. The results are validated by comparison with a 3D finite element simulation using the code ABAQUS. The influences of the geometrical characteristics and the shear effects on the buckling loads are demonstrated through several case studies.

• Bulletin of the Korean Chemical Society
• /
• 제9권1호
• /
• pp.36-40
• /
• 1988

The time correlation functions of concentration fluctuations due to the random forces near the steady state are evaluated for a general two-component nonlinear chemical system by solving the corresponding two dimensional Fokker-Planck equation. The approximate method of solving the Fokker-Planck equation is based on the eigenfunction expansion and the corresponding eigenvalues for both the linear and nonlinear Fokker-Planck operators are obtained near the steady state. The general results are applied to the Lotka model near the oscillatory marginal steady state and the comparison is made between linear and nonlinear cases.