• Title/Summary/Keyword: Gender factor

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Affecting Factors of Insulin Resistance in Obese Children and Adolescents (소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인)

  • Kim, Duk Hee;Eun, Ho Seon;Choi, In Kyung;Kim, Ho Seung;Cha, Bong Soo;Kim, Dong Kee
    • Clinical and Experimental Pediatrics
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    • v.48 no.10
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    • pp.1076-1081
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    • 2005
  • Purpose : Insulin resistance is the most important risk factor linked to the development of impaired glucose tolerance(IGT), diabetes mellitus and cardiovascular diseases in childhood and adolescent obesity, The purpose of this study was to see whether insulin resistance of obese adolescent is higher than that of obese children. and to analyze gender difference and affecting factors of insulin resistance. Methods : Of the 9,837 school children from 5 to 16 tears old, 92 obese children and 187 adolescent, underwent a two-hour oral glucose tolerance test and plasma glucose, insulin, lipid profiles, leptin and high sensitive C-reactive protein(hs-CRP) were measure. Results : Plasma insulin levels of female were higher compared to those of males during oral glucose tolerance test(P<0.05). Four(4.3%) in obese children and twenty five(13.3%) in obese adolescents met the criteria of IGT. Female, leptin, adiponectin and triglyceride concentrations were strongly correlated with homeostatic model assessment insulin-resistance(HOMA-IR) by multiple linear regression analysis(P<0.05). Conclusion : Obese adolescents might have higher insulin concentrations compared to obese children and obese girls higher insulin concentrations than obese boys. Obese boys and children with impaired glucose tolerance have higher insulin concentrations than those with normal glucose tolerance. HOMA-IR was significantly correlated with female, plasma leptin, adiponectin and triglyceride concentrations.

Assessment of Relationship between Fyn-related Kinase Gene Polymorphisms and Overweight/Obesity in Korean Population

  • Jung, Mi-Young;Kim, Bum-Shik;Kim, Youn-Jung;Koh, In-Song;Chung, Joo-Ho
    • The Korean Journal of Physiology and Pharmacology
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    • v.12 no.2
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    • pp.83-87
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    • 2008
  • The fyn-related kinase (FRK) belongs to the tyrosine kinase family of protein kinases. Recent studies have shown that Frk affects pancreatic beta cell number during embryogenesis and promotes beta cell cytotoxic signals in response to streptozotocin. To investigate the genetic association between FRK polymorphisms and the risk of obesity in Korean population, single nucleotide polymorphisms (SNPs) in the FRK gene region were selected and analyzed. The body mass index (BMI) was calculated, and biochemical data (systolic blood pressure, diastolic blood pressure, hemoglobin A1C, triglyceride, total cholesterol, high density lipoprotein, and low density lipoprotein) of blood sample from each subject were also measured. One hundred fifty five healthy control and 204 overweight/obesity subjects were recruited. Genotype frequencies of six SNPs [rs6568920 (+8391G>A), rs3756772 (+56780A>G), rs3798234 (+75687C>T), rs9384970 (+68506G>A), rs1933739 (+72978G>A), and rs9400883 (+75809A>G)] in the FRK gene were determined by Affymetrix Targeted Genotyping Chip data. According to the classification of Korean Society for the Study of Obesity, control (BMI 18 to < 23) and overweight/obesity (BMI$\geq$23) subjects were recruited. For the analysis of genetic data, EM algorithm, SNPStats, Haploview, HapAnalyzer, SNPAnalyzer, and Helixtree programs were used. Multiple logistic regression analysis (codominant, dominant, and recessive models) was performed. Age and gender as covariates were adjusted. For biochemical data, Student's t test was used. The mean value of BMI in the control and overweigh/obesity groups was 21.1${\pm}$1.2 (mean${\pm}$SD) and 25.6${\pm}$2.0, respectively. All biochemical data of the overweight/obesity group were statistically significance, compared with the control group. Among six SNPs, two linkage disequilibrium (LD) blocks were discovered. One block consisted of rs1933739 and rs9400883, and the other comprised rs3756772 and rs3798234. One SNP (rs9384970, +68506G>A) showed an association with overweight/obesity in the codominant model (p=0.03). Interestingly, the AA genotype distribution in the overweight/obesity group (n=7, 3.5%) was higher than those in the control group (n=1, 0.6%), which is not found in either Japanese or Chinese subjects. Therefore, the AA genotype of rs9384970 may be a risk factor for development of obesity in Korean population. The results suggest that FRK may be associated with overweight/obesity in Korean population.

Study of the Influence of Service Quality on Customer Satisfaction and Repurchase Intention Activation in the Performing Arts (공연예술서비스가 고객만족과 재구매 활성화 의도에 미치는 요인에 관한 연구)

  • Jeong, Je-Yoon;Park, Hyeon-Suk
    • Journal of Distribution Science
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    • v.10 no.10
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    • pp.45-57
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    • 2012
  • Purpose - This study was conducted to evaluate service quality, perceived value, and satisfaction in the performing arts in order to establish a system of relationships that predicts repurchase intention, which increasingly needs to be studied as the domestic performing arts market grows. Research design, data, and methodology - Another purpose of this study is to identify 'work-related factors' and 'performing-arts-related factors' in the performing arts industry, and to observe the influence of the core SQ factors expected to influence audiences' purchase intentions through perceived value and customer satisfaction. The empirical study to test the hypothesis was based on a review of the literature and employed the survey method; data were collected from a total of 500 audience members. Results - The major results of the analysis are as follows. First, in terms of quality factors affecting perceived value, literary quality, level, professionalism, and musical quality were shown to have a significant influence as key factors from the performing arts perspective, while reliability, convenience, and related costs were indicated to exert a significant influence as additional factors related to work. Secondly, the quality factors with a significant influence on customer satisfaction were literary quality, professionalism, and musical quality, which were shown to have a significant influence from the performing arts perspective, while only reliability was indicated to exert a significant influence on work-related factors. Third, perceived value was shown to have a strong positive (+) influence on customer satisfaction, with both perceived value and customer satisfaction exerting a significant influence on the revisit intention. Finally, according to the results a difference analysis with demographic variables, viewing variables as moderating variables, differences according to gender were indicated in the influence of literary value and lel on perceived value, and in the influence of convenience and professionalism on customer satisfaction as well. Also, in terms of the influence of perceived value on customer satisfaction, males were found to be more influenced than females. Conclusions - Based on the above results, the suggested implications of the present study are as follows. First, through the consideration of not only the crucial work perspective in performing arts services, which has been inadequate in the past, but the additional performance-related level, the previously unevenly distributed viewpoints were expanded for application. Second, in verifying the relationship between expanded quality factors and the factors that determine consumer behavior while simultaneously considering key factors and additional related factors, work-related service quality factors were shown to exert a stronger influence on perceived value and customer satisfaction than performance-related factors. Third, for service factors related to performance, the reliability factor exerts an influence on perceived value and customer satisfaction, requiring that a performance planner secure and manage diverse channels to immediately support customer requests in providing performance theater services.

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The Effect of Perceived Family Resilience on Family Strengths among University Students (대학생이 지각하는 가족탄력성이 가족건강성에 미치는 영향)

  • Hyun, Eun Min
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.3
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    • pp.165-174
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    • 2017
  • The purpose of this study was to investigate the effect of three sub-factors of family resilience on family strength as perceived by university students. The subjects were 409 university students in G area. This study investigated the perception level of family resilience and family strength, the difference in the family strength between the resilient group and non-resilient group and the effect of family resilience on family strength. The study results were as follows: First, the students' perceptions of family resilience and family strength were moderately high. Second, the students with positive perceptions of all three family resilience sub-factors (resilient group) also had a higher perceived family strength than the non-resilient group. Third, gender was found to have an influence on family strength, with the male students having a higher perceived family strength. All three sub-factors of family resilience were statistically significant and the belief system and organizational pattern had a strong influence on the family strength. In particular, the belief system was the most powerful factor affecting the family strength. The role clarity, family cohesion and family resource of the family organizational pattern were significant factors. Moreover, collaborative problem solving and open emotional communication also had a significant influence on family strength.

A Study on the Dietary Behavior and Health-Related Lifestyles of High School Students according to the Living Area in Chonbuk Province (전북지역 일부 고등학생의 거주지에 따른 식행동 및 건강관련 생활습관에 관한 연구)

  • Cha, Youn-Soo;Kim, Jong-Sun;Rho, Jeong-Ok
    • Korean Journal of Human Ecology
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    • v.10 no.2
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    • pp.89-99
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    • 2007
  • This study was conducted to investigate the dietary behavior and health-related lifestyles of high school students according to the living area in Chonbuk province, Self administered questionnaires were collected from 489 students. Statistical data analysis was completed using a SPSS v. 10.0 program. The results are summarized as follows: The average weight and height of male students in urban and rural area were 173.52cm, 65.26kg; 172.89cm, 64.02kg. The female students were 161.18cm, 52.48kg: 160.96cm, 52.82kg. The breakfast skipping ratio of students urban area were higher than the students in rural area, About 85% of students responded to have a lunch at school foodservice canteens. About 30% of students responded to have a dinner irregularly, which mainly caused by the reasons 'irregularity of life style' and 'weight control'. The ratio of snacks intake of the students were high, but female students eaten more fruits, cookies and coffee than male students. More than 50% of the students responded that one of the important influencing factor for health was 'a good eating habits'. About 44% of students in urban area and 40% of in rural area responded to take exercise one or three times a week. Students in urban area(37.3%) have more experiences of taking nutrient supplements than those in rural area(15.8%). TV/Radio (48.7%), clinic/apothec(19.0%), and family(16.0%) were essential sources of pertinent information about nutrition. The dietary behavior and health related lifestyle between the students in urban and rural area were very similar, but the female students showed more bad dietary behaviors in comparison with the male students. Therefore, they should have a gender oriented nutritional education program to correct their dietary behaviors and health-related lifestyle for health.

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Indications for Computed Tomography (CT) to Detect Renal Injury in Pediatric Blunt Abdominal Trauma Patients with Microscopic Hematuria (미세혈뇨가 있는 소아 둔상 환자에서 콩팥 손상을 감별하기 위한 전산화단층촬영의 기준)

  • Go, Cheol-Gon;Kim, Hye-Jin;Cho, Suk-Jin;Oh, Sung-Chan;Lee, Sang-Lae;Ryu, Seok-Yong
    • Journal of Trauma and Injury
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    • v.23 no.1
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    • pp.29-37
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    • 2010
  • Purpose: Controversy exists regarding whether pediatric blunt abdominal trauma patients with microscopic hematuria should undergo radiographic evaluation. Adult patients have indications such as shock and deceleration injury. This study was conducted to suggest indications for the use of CT to detect significant renal injury in pediatric blunt abdominal trauma patients with microscopic hematuria. Methods: From January 2005 to December 2009, patients less than 18 years of age with blunt abdominal trauma and microscopic hematuria who had undergone CT were included in this retrospective study. We analyzed the correlation between microscopic hematuria, shock, deceleration injury, and American Association for the Surgery of Trauma (AAST) renal injury grade. Patients were divided into two groups: the insignificant renal injury group (AAST grade 1) and the significant renal injury group (AAST grades 2-5). We compared age, gender, mechanism of injury, degree of microscopic hematuria, evidence of shock, presence of deceleration injury, and associated injuries between the two groups. We analyzed the effect of each of the above each factors on renal injury by using a logistic regression analysis. Results: Forty-three children were included, and the median age was 15 years. Five children had a significant renal injury. No significant differences, except age and microscopic hematuria (more than 30 red blood cells per high power field (RBC/HPF), p = 0.005) existed between the insignificant and the significant injury groups. A positive correlation existed between renal injury and microscopic hematuria (rho = 0.406, p = 0.007), but renal injury was not correlated with shock and deceleration injury. In the multivariate regression analysis, microscopic hematuria was the only factor correlated with renal injury (p = 0.042). Conclusion: If a microscopic hematuria of more than 30 RBC/HPF exists, the use of CT should be considerd, regardless of shock and deceleration injury to detect significant renal injury in pediatric blunt abdominal trauma patients.

Significance of HPV Infection and Genic Mutation of APC and K-ras in Patients with Rectal Cancer

  • Sun, Zhen-Qiang;Wang, Hai-Jiang;Zhao, Ze-Liang;Wang, Qi-San;Fan, Chuan-Wen;Kureshi, Kureshi;Fang, Fa
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.121-126
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    • 2013
  • Background: Significance of HPV infection and genic mutation of APC and K-ras in rectal cancer has been investigated but not clarified. The objective of our study was to investigate these parameters in patients with rectal cancer to analyze correlations with biological behaviour, to determine relationships among the three, and also to demonstrate survival prognosis effects. Methods: From December 2007 to September 2008, 75 rectal cancer cases confirmed by histopathology in the Tumor Hospital of Xinjiang Medical University were enrolled. The control group consisted of normal rectal mucous membrane taken simultaneously, a least 10 cm distant from the carcinoma fringe. HPV DNA, the MCR of APC and exon-1 of K-ras were detected by PCR and PCR-SSCP. All results were analyzed in relation to clinical pathological material, using chi-square and correlation analysis via SPSS.13 and Fisher's Exact Probability via STATA. 9.0. All 75 patients were followed up for survival analysis using Kaplan-Meier and Log-rank tests. Results: 55 out of 75 cases demonstrated gene HPV L1 while it was notdetected in normal rectal mucosa tissue. HPV infection was correlated with age and lymphatic metastasis (P<0.05) but not other characteristics, such as ethnicity, tumor size, histological type, tumor type, Duke's stage and infiltration depth. Some 43 cases exhibited APC genic mutation (57.3%) and 34 K-ras genic mutation (45.3%). APC genic mutation was correlated with gender(P<0.05), but not age, histological type, infiltration depth, lymphatic metastasis and Duke's stage. In 55 cases of rectal cancer with HPV infection, there were 31 cases with genic mutation of APC (56.4%) and 24 with genic mutation of K-ras (43.6%). For the 20 cases of rectal cancer with non-HPV infection, the figures were 12 cases (60%) and 10 (50.0%), respectively, with no significant relation. Survival analysis showed no statistical significance for K-ras genic mutation, APC genic mutation or HPV infection (P>0.05). However, the survival time of the patients with HPV infection was a little shorter than in cases without HPV infection. Conclusions: Our results suggest that HPV infection might be an important factor to bring about malignant phenotype of rectal cancer and influence prognosis. Genic mutation of APC and K-ras might be common early molecular events of rectal cancer, but without prognostic effects on medium-term or early stage patients with rectal cancer.

A study of the effects of dance themed movies on the dance passion and affect of dance students (춤을 소재로 한 영화가 무용전공생의 무용열정과 정서에 미치는 영향에 관한 연구)

  • Park, Juhee
    • Trans-
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    • v.6
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    • pp.97-127
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    • 2019
  • This study investigated the specific effects of dance themed movies on dance students in their passion for dance and affect. The related data is generated by choosing a method of Convenience Sampling and used a sample of 112 dance students in high school of arts which located in Seongnam-si, South Korea. The dance students divided into 3 group of school year and also 2 group of gender. The dance themed movies which are used in this research are First Position, Billy Elliot and Mao's Last Dancer. Also, the dance students were asked to answer the survey which are based on the Self-administration. In order to obtain several findings below, Frequency analysis, Exploratory factor analysis, Reliability analysis, t-test, ANOVA, Correlation analysis and Linear structural relation model were applied to the gathered data using statistics utility SAS 9.4. First, there was a significant difference between the school years in the passion for dance and affect of students after watching movies. Second, there was a significant difference in students' affect depended on their majors (dance major is divided into three specialized major which are ballet, korean dance and modern dance). Third, there was a significant difference in the passion for dance and students' affect which is irreverent to their dance career (such as years they have learned dance). Forth, there was a significant difference in the passion for dance and negative affect of 'dance' students after watching movies. To summarize, the findings demonstrate that there is a partial difference, specially significant effects on their negative affect in the dance passion and affect of dance students depended on their characteristics after watching dance themed movies.

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A Study on Determinants of Trade Show's Participation Fees (무역전시회 참가비용의 결정요인에 관한 연구)

  • Cho, Yun-Sil
    • Management & Information Systems Review
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    • v.28 no.3
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    • pp.99-115
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    • 2009
  • This research analyzed determining factors of expenditure for processing fee by targeting trade show participants under a microeconomic approach in order to analyze determining factors of the participations of trade shows. As a result, with regard to the participation fees, income and the level of education seemed to be the socioeconomic factors that positively affected visitors in paying admission fees: and age and gender were negative elements. With regard to the participating businesses, the sales and the corporate history of the businesses were the positive elements to their willingness to pay the participation fees: however, the ratio of male and female personnel turned out to be a negative element in incurring the participation fees. The purchase of ticket was a positive mode-of participation factor to the visitors: however, distance tended to be a negative element for the visitors. For the participating businesses, the number of participation tended to be a positive element: however, distance was a negative one. The positive satisfaction factors that affected visitors' willingness to pay the participation fees included exhibited items, location, and schedules for events of the convention: for the participating businesses, the actual sales at the convention, the effects of advertisement and the level of satisfaction for location tended to play positive parts.

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An Analysis of Middle School Students' Perceptions and Learning Satisfaction in SMART Learning-based Science Instruction (스마트러닝 기반 과학수업에 대한 중학생들의 인식과 학습만족도 분석)

  • Park, Su-Kyeong
    • Journal of the Korean earth science society
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    • v.34 no.7
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    • pp.727-737
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    • 2013
  • The purpose of this study was to investigate the middle school students' perception and their learning satisfaction in SMART learning based science instruction. Three types of modules on the solar system and lunar phases unit at the middle school level were developed and lessons on each module were taught to 207 student participants. All participants were provided with tabletPC(iPad2) with iOS5 installed, and using astronomy app Solar Walk, mirroring function, QR code, and Google Presentation, the lessons were carried out both in classroom and at home. The instrument for assessing students' perception on the SMART learning-based instruction was developed based on 4 factors including Self-directed, Motivation, Adaptiveness, and Technology Embedded, with a Likert scale from 1-5 on 20 items. The learning satisfaction survey instrument was originally from Keller's work (1987), and its test items were adapted and modified. To reveal the perception and learning satisfaction about SMART learning-based science lessons, the participants were comparatively analyzed by gender and science achievement levels. Results indicated that male students showed positive perception for the SMART learning-based instruction. Group with higher science achievement scores showed more positive perception of the SMART learning-based instruction in terms of Self-directed and Motivation factor. Also, the learning satisfaction of male students was higher than female students and group with higher academic ability more satisfied with the SMART learning-based instruction than the low group. The results provide implications for future development of programs and help set a direction of increasing the use of a SMART learning-based science in school.