• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.11 no.1
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• pp.240-250
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• 1998

Background: Ginkgo biloba extract is used in disorser of cerebral and peripheral blood circulation, dysfunction of brain, atherosclerosis etc., but there are little study about GbE in oriental medicine. We wished to assessthe efficacy of GbE for the treatment of cerebral infarction Method : The study group comprised 40 patients who arrived at hospital during 48 hours after attack. All patient were devided into two group. The control group was treated with Uhuangcheongsimhuan, Seonghyangjeonggisan, acupuncture therapy only, while the GbE group was treated with above therapy plus 5 days of administration of GbE(40mg three times per day). Result: 1. Symptom improve scores did not showed significant difference between control and GbE group. 2. Vasoreactivity of carotid siphon increased significantly in GbE group after treatment (in the left only : p<0.05). 3. Vasorcactivity of radial artery increased significantly in GbE group after treatment(in the right only ; p<0.05). 4. PT, a-PTT, Fibrinogen did not showed significant changes between before and after treatment in both group. Conclusion: These findings suggest that vasoreactivity increasing effect of GbE may be useful in the prevention and treatment of cerebral infarction. But the vasoreactivity increasing effect of GbE may be different from symptom imroving.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.12A
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• pp.945-950
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• 2003

The link aggregation between 10GbE switches requires an advanced frame distribution method to be properly and efficiently applied. The fixed or dynamic frame distribution methods, formerly proposed, cannot fully utilize the aggregated links, where the receiving terminal only attaches to a pre-specified link among multiple physical links. A frame distribution method using tagging is proposed for the link aggregation between 10GbE switches to solve this problem. We compared the performance of the proposed method with those of the fixed and dynamic frame distribution methods. As a result, the proposed method shows a better performance when the applied load is below 0.7 and the average length of the frames is longer than 954 bytes.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.5B
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• pp.809-815
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• 2010

This paper proposes the structures and algorithms for the adaptive equalizer that are required to allow high speed signaling over 40 Gb/s across a backplane channel. The proposed adaptive DFE has a fast convergence and low computational complexity. Simulations with a 40 Gb/s show that our adaptive equalizer can meet the IEEE 802.3ba requirement for backplane strip line up to 40 inches.

• Korean Journal of Veterinary Research
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• v.44 no.2
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• pp.233-239
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• 2004

This study was designed to quantitative assay of cellular receptor globotriosyl ceramide($Gb_3$) and globotetraosyl ceramide($Gb_4$) and to determine binding affinity of the receptors for Shigatoxin 2e in difference with day olds of pig. The amount of $Gb_3$ and $Gb_4$ extracted from each swine tissue were detected in order of spleen, ileocecum, kidney, and jejunum. The amount of $Gb_3$ and $Gb_4$ extracted from each swine ileocecum and jejunum in different day old swine were detected in order of 24, 6, 98, 12 and 35, but the difference of amount was not significant. The binding affinity of $Gb_4$ extracted from ileocecum and jejunum with different day old swine for Stx2e were shown that the extracts of 24, 12, and 35 days old swine were higher significantly than that of 6 and 98 days old swine.

• Clinical and Experimental Pediatrics
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• v.46 no.2
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• pp.143-153
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• 2003

Purpose : Infection with Shiga-like toxin (SLT)-producing Escherichia coli, an emerging human pathogen found particularly in young children under 5 years of age, causes a spectrum of illnesses with high morbidity and mortality, ranging from diarrhea to hemorrhagic colitis and hemolytic uremic syndrome. Host mediators play an important role in the pathogenesis of SLT-I toxicity. The experiments described here were designed to investigate the effect of SLT-I on TNF-${\alpha}$ production and to understand the effect of TNF-${\alpha}$ on GB3 expression. We also further examine the relationship between the Gb3 level and the differential susceptibility of cells to the cytotoxic action of SLT-I. Methods : The effect of purified SLT-1 from E. coli O157 : H7 (ATCC 43890) on tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) production in Raw264.7 cells was investigated. Many mediators regulate endothelial cell membrane expression of the glycolipid globotriaosyleramide (Gb3), which serves as the toxin receptor, suggesting that the host response to the toxin or other bacterial products may contribute to pathogenesis by regulating target cell sensitivity to the toxins. Therefore, the relationships between Gb3 expression and cytotoxicity against SLT-I on three types of cells were evaluated. Results : Detectable levels of TNF-${\alpha}$ were produced as early as six hours after induction and continued to increase during 48 hours by SLT-I. It was also found that Vero cells and dendritic cells (DC2.4 cells) expressed high levels of Gb3, 83% and 68%, respectively, and that Raw264.7 cells had a low level of Gb3 (29%) and appeared refractory to cytotoxicity against SLT-I. Vero cells and DC2.4 cells expressing high levels of Gb3 were highly susceptible to SLT-I. Furthermore, macrophages showed a resistance to SLT-I cytotoxicity, despite the fact that Gb3 expression was enhanced. Conclusion : These results strongly suggest that the expression of Gb3 is necessary but not sufficient to confer sensitivity of macrophages to SLT-I and further underpin the important role of SLT-I and its Gb3 receptors in the pathogenesis of E. coli O157 infection.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.23 no.5
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• pp.368-373
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• 2010

In this study, we have investigated the effects of Cr dopant on the bulk trap levels and grain boundary characteristics of $Bi_2O_3$-based ZnO (ZB) varistor using admittance spectroscopy and dielectric functions (such as $Z^*,\;Y^*,\;M^*,\;{\varepsilon}^*$, and $tan{\delta}$). Admittance spectra show more than two bulk traps of $Zn_i$ and $V_o$ probably in different ionization states in ZnO-$Bi_2O_3-Cr_2O_3$ (ZBCr) system. Three kinds of temperature-dependant activation energies ($E_{bt}'s$) were calculated as 0.11~0.14 eV of attractive coulombic center, 0.16~0.17 eV of $Zn_{\ddot{i}}$, and 0.33 eV of $V_o^{\cdot}$ as dominant bulk defects. The grain boundaries of ZBCr could be electrochemically divided into two types as a sensitive to ambient oxygen i.e. electrically active one and an oxygen-insensitive i.e. electrically inactive one. The grain boundaries were electrically single type under 460 K (equivalent circuit as parallel $R_{gb1}C_{gb1}$) but separated as double one ($R_{gb1}C_{gb1}-R_{gb2}C_{gb2}$) over 480 K. It is revealed that the dielectric functions are very useful tool to separate the overlapped bulk defect levels and to characterize the electrical properties of grain boundaries.

• Journal of Life Science
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• v.17 no.4 s.84
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• pp.482-492
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• 2007

Infection with Shiga-like toxin (SLT)-producing Escherichia coli causes a spectrum of illnesses with high morbidity and mortality. Host mediators play an important role in the pathogenesis of SLT-I toxicity. We here investigated the effect of SLT-I on tumor necrosis $factor-{\alpha}\;(TNF-{\alpha})$ production, effect of $TNF-{\alpha}$ on glycolipid globotriaosyleramide (Gb3) expression, and relationship between Gb3 level and differential susceptibility of cells to SLT-I. In this study, we observed that detectable levels of $TNF-{\alpha}$ are produced 6 hrs after induction and continued to increase during 48 hrs by SLT-I. It was also found that Vero cells and dendritic cells expressed high levels of Gb3, 83% and 68%, respectively, and that macrophages had a low level of Gb3 (29%) and showed refractory to cytotoxicity against SLT-I. Vero cells and dendritic cells expressing high levels of Gb3 were highly susceptible to SLT-I. furthermore, macrophages showed a resistance to SLT-I cytotoxicity, despite the fact that Gb3 expression was enhanced. These results suggest that the expression of Gb3 is necessary, but not sufficient to confer sensitivity of macrophages to SLT-I and further underpin the important role of SLT-I and its receptor, Gb3, in the pathogenesis of E. coli O157 infection.

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 2004.11a
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• pp.90-90
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• 2004

• Journal of information and communication convergence engineering
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• v.3 no.1
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• pp.13-17
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• 2005

The link e daggregation between 10GbE switches requires an advanced framistribution method to be properly and efficiently applied. The fixed or dynamic frame distribution methods, formerly proposed, cannot fully utilize the aggregated links, where the receiving terminal only attaches to a pre-specified link among multiple physical links. A frame distribution method using padding is proposed for the link aggregation between 10GbE switches to solve this problem. We compared the performance of the proposed method with those of the static and dynamic frame distribution methods. As a result, the proposed method shows a better performance when the offered load is below 0.7 and the average length of the frames is longer than 954 bytes.

• Proceedings of the Korean Information Science Society Conference
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• 2003.04d
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• pp.25-27
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• 2003

본 논문은 10GbE로의 망 전개에 따라 구현될 l0Gb 스위치에 필요한 계층2 부가서비스들 중에서 여러개의 물리적인 링크를 하나의 논리적인 링크로 집합하여 대역폭의 증가를 가져오는 링크 집합(Link Aggregation) 기술에 필요한 프레임 분배방식에 대한 것이다. 링크 집합 기술은 분배 알고리즘의 설계에 따라 스위치에서 성능의 차이를 가져오므로 링크 집합의 장정을 살리려면 종은 성능을 가지는 분배 알고리즘이 필요하다. 우선 링크 집합의 간단한 구현 방법을 살펴보고 기존에 제시된 스위치와 스위치 사이에서의 프레임 분배방식인 정적/동적 프레임 분배 방식과 우리가 새로이 제안한 패딩을 이용한 분배방식을 비교한 후, 정적/동적 프레임 분배 방식과 패딩을 이용한 분배방식을 컴퓨터 시뮬레이션을 통해 성능을 비교하였다.