• Journal of Preventive Medicine and Public Health
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• v.43 no.4
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• pp.309-318
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• 2010

Objective: This study was performed to investigate the prevalence of impaired fasting glucose (IFG) and its related characteristics among healthy adults in some Korean rural areas. Methods: We conducted a cross-sectional study using the data from 1352 adults who were over the age 40 and under the age 70 and who were free of diabetes mellitus (DM), cardiovascular diseases and other diseases and who participated in a survey conducted as part of the Korean Rural Genomic Cohort Study. IFG was defined as a serum fasting glucose level between 100 and 125 mg/dL. Results: The prevalence of IFG was 20.4% in men, 15.5% in women and 12.7% overall. Multivariate logistic regression analysis demonstrated that the independent risk factors for IFG were male gender, having a family history of DM, the quartiles of gamma glutamyltransferase and high sensitive C-reactive protein and the waist circumference. The homeostatis model assessment for insulin resistance was very strongly associated with IFG. The prevalence of metabolic syndrome (MS) and MS components was higher in the subjects with IFG then in those with normal fasting glucose (NFG). Conclusions: The result of study could supply evidence to find the high risk population and to determine a strategy for treating IFG. Further research is needed to explain the causal relationship and mechanisms of IFG.

• The Korean Journal of Ecology
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• v.27 no.2
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• pp.79-86
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• 2004

An extensive study of the vegetation characteristics of the Hamersley Ranges, a mountainous desert area of north-west Australia, facilitated the comparison of plant species diversity measures with mountainous deserts of other parts of the world. Alpha diversity was defined as the number of species co-existing at local scales and was found to average 18 species per 0.1 ha for the Hamersley Ranges. This was found to be similar to seven other mountainous deserts in North and South America, and southern Africa. Variation in alpha diversity between these deserts was found to considerably lower than within deserts, suggesting that local processes control species richness at local scales. Beta diversity, defined here as turnover in species composition at various spatial scales, can be measured in many ways. For the Hamersley Ranges, Wilson's β ranged from 1.2 to 1.6 for five sites along a topographic gradient, whereas Whittaker's β between different plant communities was found to average 0.93. Comparable data was not found for other desert areas, but comparisons to non-desert areas suggest beta diversity within landscapes is relatively high and is likely to reflect the considerable landform heterogeneity of the Hamersley Ranges. 55∼70% of species were shared between different landscapes of the Hamersley Ranges; comparisons to other regions suggest beta diversity at this scale is relatively low. Gamma diversity, the number of species over large spatial extents, was successfully compared using regression analysis of the log-log species - area relationship. This revealed that the northern Sonoran desert has significantly less species than the Nama (inland) Karoo and Hamersley Ranges over medium spatial extents, but species numbers were similar at a regional scale. Several constraints to the valid comparison of species diversity were identified, including lack of standardisation of sampling techniques, the wide range of measures employed, general lack of published data, and the influence of the various components of spatial scale on most diversity measures. Recommendations on how to improve future comparative work are provided.

• The Korean Journal of Nuclear Medicine
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• v.21 no.2
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• pp.151-154
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• 1987

Total 114 patients were studied prospectively with radioiodine uptake (RAIU) and $^{99m}TcO_4^-$ thyroid scan to design a very simple, rapid and inexpensive method measuring the thyroid uptake on thyroid scan. After the RAIU was obtained at 24 hours after P.O. of $^{131}I$, Thyroid scan was performed at 20 minutes after LV. of $^{99m}TcO_4^-$ and the bilateral salivary glands were included in the scan field. Pinhole collimated and computer assisted gamma camera was used. Three regions of interest were set on each salivary gland and on the thyroid by automatic edge detection method. Mean counts per pixel were calculated for each ROI and the salivary-thyroid ratio (STR) was defined as; $$STR(%)=\frac{Mean\;counts\;per\;pixel\;of\;salivary\;glands\;(KC)}{Mean\;counts\;per\;pixel\;of\;thyroid\;gland\;(KC)}\times100$$ 114 cases consisted of 41 normal, 55 hyperthyroid and 18 hypothyroid patients and correlation between the STR and the RAID were evaluated in total and each group. The STR and the RAID showed reverse linear regression in 114 cases (r= -0.8, P=0) and closer correlation was shown in hyperthyroid group (r= -0_9, p=0). Mean STR in normal group was 47.6%. In predicting the RAID by STR, sensitivity and specificity were 88.3% and 64.9% in 114 cases and 95.3% and 83.3% in hyperthyroid group. It is recommended that the STR be used in place of the RAID giving same information at saving time, money and radiation exposure.

• Journal of Korean Neurosurgical Society
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• v.43 no.2
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• pp.90-96
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• 2008

Objective: Delayed ischemic deficit or cerebral infarction is the leading cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage (SAH). The purpose of this study is to reassess the prognostic impact of intraoperative elements, including factors related to surgery and anesthesia, on the development of cerebral infarction in patients with ruptured cerebral aneurysms. Methods: Variables related to surgery and anesthesia as well as predetermined factors were all evaluated via a retrospective study on 398 consecutive patients who underwent early microsurgery for ruptured cerebral aneurysms in the last 7 years. Patients were dichotomized as following; good clinical grade (Hunt-Hess grade I to III) and poor clinical grade (IV and V). The end-point events were cerebral infarctions and the clinical outcomes were measured at postoperative 6 months. Results: The occurrence of cerebral infarction was eminent when there was an intraoperative rupture, prolonged temporary clipping and retraction time, intraoperative hypotension, or decreased $O_2$ saturation, but there was no statistical significance between the two different clinical groups. Besides the Fisher Grade, multiple logistic regression analyses showed that temporary clipping time, hypotension, and low $O_2$ saturation had odds ratios of 1.574, 3.016, and 1.528, respectively. Cerebral infarction and outcome had a meaningful correlation (${\gamma}$=0.147, p=0.038). Conclusion: This study results indicate that early surgery for poor grade SAH patients carries a significant risk of ongoing ischemic complication due to the brain's vulnerability or accompanying cardio-pulmonary dysfunction. Thus, these patients should be approached very cautiously to overcome any anticipated intraoperative threat by concerted efforts with neuro-anesthesiologist in point to point manner.

• Journal of radiological science and technology
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• v.45 no.6
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• pp.491-502
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• 2022

The purpose of this study was to retrospectively investigate the upper and lower control limits of treatment planning parameters using EBT film based delivery quality assurance (DQA) results and to analyze the results of statistical process control (SPC) in helical tomotherapy (HT). A total of 152 patients who passed or failed DQA results were retrospectively included in this study. Prostate (n = 66), rectal (n = 51), and large-field cancer patients, including lymph nodes (n = 35), were randomly selected. The absolute point dose difference (DD) and global gamma passing rate (GPR) were analyzed for all patients. Control charts were used to evaluate the upper and lower control limits (UCL and LCL) for all the assessed treatment planning parameters. Treatment planning parameters such as gantry period, leaf open time (LOT), pitch, field width, actual and planning modulation factor, treatment time, couch speed, and couch travel were analyzed to provide the optimal range using the DQA results. The classification and regression tree (CART) was used to predict the relative importance of variables in the DQA results from various treatment planning parameters. We confirmed that the proportion of patients with an LOT below 100 ms in the failure group was relatively higher than that in the passing group. SPC can detect QA failure prior to over dosimetric QA tolerance levels. The acceptable tolerance range of each planning parameter may assist in the prediction of DQA failures using the SPC tool in the future.

• The Korean Journal of Pain
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• v.36 no.4
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• pp.425-440
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• 2023

Background: Muscimol's quick onset and GABAergic properties make it a promising candidate for the treatment of pain. This systematic review and meta-analysis of preclinical studies aimed at summarizing the evidence regarding the efficacy of muscimol administration in the amelioration of nerve injury-related neuropathic pain. Methods: Two independent researchers performed the screening process in Medline, Embase, Scopus and Web of Science extracting data were extracted into a checklist designed according to the PRISMA guideline. A standardized mean difference (SMD [95% confidence interval]) was calculated for each. To assess the heterogeneity between studies, ² and chi-square tests were utilized. In the case of heterogeneity, meta-regression and subgroup analyses were performed to identify the potential source. Results: Twenty-two articles met the inclusion criteria. Pooled data analysis showed that the administration of muscimol during the peak effect causes a significant reduction in mechanical allodynia (SMD = 1.78 [1.45-2.11]; P < 0.0001; I² = 72.70%), mechanical hyperalgesia (SMD = 1.62 [1.28-1.96]; P < 0.0001; I² = 40.66%), and thermal hyperalgesia (SMD = 2.59 [1.79-3.39]; P < 0.0001; I² = 80.33%). This significant amendment of pain was observed at a declining rate from 15 minutes to at least 180 minutes post-treatment in mechanical allodynia and mechanical hyperalgesia, and up to 30 minutes in thermal hyperalgesia (P < 0 .0001). Conclusions: Muscimol is effective in the amelioration of mechanical allodynia, mechanical hyperalgesia, and thermal hyperalgesia, exerting its analgesic effects 15 minutes after administration for up to at least 3 hours.

• Journal of the Korean Society of Groundwater Environment
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• v.1 no.1
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• pp.23-32
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• 1994

To determine the apparent equilibrium constants, K$_{ad,app}$, for the adsorption reactions of trace metals on amorphous iron oxyhydroxide (AIO) in the Taebag coal mine area, time-adsorption and pH-adsorption experiments were performed for a selected bottom sediment mainly comprised of AIO from the study area. The results from the adsorption experiments indicate that most of the trace metals, except Pb, achieve equilibrium states with AIO and thus, the calculated K$_{ad,app}$ may represent the true apparent equilibrium constants. K$_{ad,app}$ and the stoichiometric coefficients of proton, x, of the adsorption reactions between the trace metals and AIO were respectively calculated from the intercepts and slopes of the regression lines of log($\Gamma$/ ［M］$_{aq}$)against pH provided by pH-adsorption experiments. The calculated K$_{ad,app}$ this study has the values of the range from 10$^{－4.5}$ to 10$^{2.75}$ , which is much different from the reported values by other investigators for simple experimental systems. K$_{ad,app}$ of this study is more or less close but not exactly pertinent to the estimated values for the other natural systems. It indicates that K$_{ad,app}$ for the adsorption reactions in the aquatic system in the study area is unique and thus should be determined befor the adsorption modelling. The calculated x of this study has the values of the range from -0.3 to 0.7, which is also much different from what most geochemists generally accept. The discrepancy in x may be due to the competition among different kinds of ionic species on the adsorption site or simulataneous occurrence of different kinds of adsorption reactions. The results from this study should help construct an appropriate adsorption model for the aquatic systems polluted by the coal mine drainage in the Taebag area. With the constructed model, one can describe the concentration variations of trace metals due to the adsorption in the system, which is an essential part of the investigation on the water quality affected by coal mine drainage in the Taebag coal field.

• Tuberculosis and Respiratory Diseases
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• v.44 no.3
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• pp.611-620
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• 1997

Objectives : The differentiation of tuberculous effusion from the other causes of exudative pleural effusion remained difficult even with aids of biochemical analyses and pleural biopsy. As the pathophysiology of tuberculous pleural effusion is an enhanced cell mediated immunity, Adenosine deaminase(ADA) and various eytokines including Inteferon-$\gamma$, tumor necrosis factor alpha(TNF-$\alpha$) are considered as useful diagnostic tools in differentiating exudative pleural effusion. The author would like to demonstrate the diagnostic usefulness of TNF-$\alpha$ in the differentiation of exudative pleural effusion, and compared the discriminating ability of TNF-$\alpha$ with ADA. Methods : Pleural fluids obtained from 80 patients (tuberculous : 39, malignant : 31, parapneumonic : 10) with exudate pleural effusions were processed for cell counts and biochemical analysis including ADA and TNF-$\alpha$. Results : Tuberculous pleural fluid showed higher levels of ADA and TNF-$\alpha$, $48.7{\pm}32.7U/L$ and $184.1{\pm}214.2pg/mL$ than that of non-tuberculous effusion $26.0{\pm}41.3U/L$ and $44.1{\pm}114.2pg/mL$, respectively (ADA, TNF-$\alpha$, p < 0.05, p < 0.01). Receiver operating characteristics(ROC) curves were generated for ADA and TNF-$\alpha$ and the best cut-off value for adenosine deaminase and TNF-$\alpha$were considered as 30U/L and 15pg/ml, respectively. Comparing the area under the ROC curves, there was no significant difference between ADA and TNF-$\alpha$. Conclusion : For the differential diagnosis of tuberculous pleural effusion from the other causes of exudative pleural effusions, TNF-$\alpha$ as well as ADA was considered as useful diagnostic method. However adding TNF-$\alpha$ to ADA has no further diagnotic benefit than ADA alone.

• Journal of the Korean Association of Geographic Information Studies
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• v.25 no.1
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• pp.133-149
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• 2022

Existing domestic studies on estimating rice yield were mainly implemented at the level of cities and counties in the entire nation using MODIS satellite images with low spatial resolution. Unlike previous studies, this study tried to estimate rice yield at the level of eup-myon-dong in Gimje-si, Jeollabuk-do using Sentinel-2 satellite images with medium spatial resolution, rainfall and soil data, and then to evaluate its accuracy. Five vegetation indices such as NDVI, LAI, EVI2, MCARI1 and MCARI2 derived from Sentinel-2 images of August 1, 2018 for Gimje-si, Jeollabuk-do, rainfall and paddy soil-type data were aggregated by the level of eup-myon-dong and then rice yield was estimated with gamma generalized linear model, an expanded variant of multi-variate regression analysis to solve the non-normality problem of dependent variable. In the rice yield model finally developed, EVI2, rainfall days in September, and saline soils ratio were used as significant independent variables. The coefficient of determination representing the model fit was 0.68 and the RMSE for showing the model accuracy was 62.29kg/10a. This model estimated the total rice production in Gimje-si in 2018 to be 96,914.6M/T, which was very close to 94,470.3M/T the actual amount specified in the Statistical Yearbook with an error of 0.46%. Also, the rice production per unit area of Gimje-si was amounted to 552kg/10a, which was almost consistent with 550kg/10a of the statistical data. This result is similar to that of the previous studies and it demonstrated that the rice yield can be estimated using Sentinel-2 satellite images at the level of cities and counties or smaller districts in Korea.

• Journal of Sericultural and Entomological Science
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• v.18 no.1
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• pp.21-26
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• 1976

The study was carried out to investigate the variations in the fibroin hydrolysis of different cocoon shell layers, and the relationship between the hydrolysis and silk physical property. The obtained results are as follows: 1. The fibroin hydrolyzing ratio was highest at the inner layer of cocoon shell and. next in order. at the middle layer and at the outer layer. 2. The fibroin hydrolyzing ratio of abnormal cocoons was higher than normal cocoon and it was different among them, tile highest was double coroon, thin shell cocoon and perforated cocoon in order. 3. The sericin content and fibroin hydrolyzing ratio of Jam 111 and Jam 112 was higher than that of Jam 111 $\times$ Jam 112. 4. The fibroin hydroiyzing ratio of the cocoons fed with the artificial diets was increased at the inner layer. The sericin content of those lessened at the inner layer, however, it slightly increased at the most inner layer more than at the inner layer. 5. The breaking strength of the degummed silk fiber of different cocoon layers was reduced at the inner layer. The breaking Strength of abnormal silk fiber was less than that of normal silk fiber. 6. A negative correlation (r= －0.8) )was approved between fibroin hydrolyzing ratio and breaking strength of silk fiber, and the regression line was Y=－0.29x＋5.07.