• 방사선산업학회지
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• 제7권1호
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• pp.55-59
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• 2013

Ionizing radiation causes the massive generation of reactive oxygen species, resulting in cellular and tissue damage. The present study was performed to evaluate ${\gamma}$-irradiation induced cellular damage in ICR mice. The mice were divided into four groups with ten mice in each group. Group 1 served as an unexposed control group. Groups 2, 3, and 4 were exposed to 3, 5, and 7 Gy of ${\gamma}$-radiation, respectively. Five mice per group were sacrificed 1 and 7 days after ${\gamma}$-radiation. Exposure to ${\gamma}$-irradiation resulted in hematopoietic damage in a dose-dependent manner when compared with the unexposed control group, which featured a significantly decreased spleen index. However, the exposed mice showed no significant differences in their serum AST, ALT and in the histopathological change of their liver. These results suggest that ${\gamma}$-irradiation is a good tool to prepare a hematopoietic damage model. This animal model can be employed to study the hematopoietic efficacy of biologically active compounds.

• 대한방사선치료학회지
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• 제23권2호
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• pp.97-102
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• 2011

목 적: 2차원 배열 검출기를 이용하여 세기변조 방사선 치료 품질관리를 시행할 때 정량적 분석을 위한 감마(${\gamma}$) 함수의 적용은 일반적으로 연속적인 선량 분포에 대해 정의되어 있으나 임상적으로 불연속적인 지점에 대해 측정된 값이 이용되고 있으며 이는 감마(${\gamma}$) 지수법을 이용한 평가의 불확실성과 관련이 있을 것으로 사료된다. 본 논문은 두경부암 세기변조 방사선 치료 품질관리의 감마(${\gamma}$) 함수 적용에서 표본 추출 간격에 따른 감마(${\gamma}$) 지수 변화정도를 확인하고 불확실성을 평가하여 유효한 범위를 제시하고자 한다. 대상 및 방법: 본원에서 시행한 두경부 세기변조 방사선 치료 환자 10명을 대상으로 IBA Dosimetry사의 OmniPro I'mRT system software version 1.7b를 이용하여 동일한 두 선량 평가면(Plane)에 대해 분석을 시행하였다. 원점에 위치한 표본 추출 간격 0.1 cm의 선량 평가면을 기준으로 다른 하나의 선량 평가면 위치를 Y축 방향으로 0.0 cm, 0.2 cm, 0.5 cm, 1.0 cm씩 이동 시키면서 Gamma pass rate, Average signal, 측정값에 대한 표준편차의 변화를 관찰하였다. 이때 표본 추출 간격을 0.1 cm, 0.5 cm, 1.0 cm, 2.0 cm, 4.0 cm으로 변화시키면서 Y축 방향으로 동일한 거리를 이동했을 때 Gamma index의 변화를 실험하였다. 결 과: 각 표본추출 간격에 대해 Average signal의 차이는 0, -0.0019, -0.0004, -0.0460, -0.832로 나타났고 측정값에 대한 표준편차의 차이는 0, -0.0030, 0.0124, 0.0070, -0.0799로 나타났으며 Gamma pass rate의 차이는 0, 0.0027, -0.0143, 0.0532, 0.0560의 결과를 보였다. 표본추출 간격 0.1~1.0 cm 범위 내에서는 Average signal과 Gamma pass rate의 차이가 1.5% 이내로 나타났으며 2.0 cm 이상 범위에서는 5% 이상 차이를 보였다. 결 론: 감마(${\gamma}$) 함수의 적용에서 표본추출 간격이 1.0 cm 이하인 경우 실제 분석 값에 대해 1.5% 이내의 차이를 나타냈지만 2.0 cm 이상인 경우 Gamma pass rate이 실제 분석 값보다 5%이상 높게 나타났고 감마(${\gamma}$) 지수의 불확실성과 신뢰수준에 영향을 주었다. 세기변조 방사선 치료의 품질관리를 시행할 경우 표본추출 간격에 따른 감마(${\gamma}$) 지수의 불확실성을 고려하여 임상적으로 2.0 cm 미만의 표본 추출 간격이 적용되어야 할 것으로 사료된다.

• Journal of Nutrition and Health
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• 제35권3호
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• pp.368-379
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• 2002

This study investigated the correlations among the health consciousness, nutrition knowledge, dietary habits and nutrition attitudes of school teachers. The subjects of this study were 75 male and 152 female leachers in elementary and middle schools in Masan city. The survey was conducted by using a questionnaire. Even though the average body mass index (BMI) and the obesity index were normal in both male and female subjects, 33.3% of the male subjects were overweight/obese, while 18.5% of the female subjects were underweight, according to the obesity index. The food components of most concern during mealtime were (in order of importance) salt, MSG and cholesterol by male subjects, and salt, fat and MSG by female subjects. The subjects considered self-relaxation as the most important factor in maintaining optimal health status, followed by resting, bathing or use ova sauna, moderation in diet, exercise, decreasing alcohol intake, and no smoking. Newspapers/magazines and TV/radio were the primary sources of nutrition and health information of the subjects. As the degree of health consciousness increased, scores of the dietary habits and nutrition attitudes increased. Nutrition knowledge scores and nutrition altitudes scores increased with subjects'increased level of perception of the importance of acquiring nutrition knowledge and nutrition information. There was a highly significant correlation between the degree of health consciousness and dietary habit score (${\gamma}$ : 0.3, p<0.001). The degree of health consciousness was also significantly correlated (${\gamma}$=0.6, p<0.001) with nutrition attitudes scores. But the correlation between the degree of health consciousness and nutrition knowledge was not statistically significant. The degree of the perception of the importance of nutrition knowledge showed a positive correlation with nutrition attitude (${\gamma}$:0.4, p<0.001) and dietary habit (${\gamma}$:0.3, p<0.001). The degree of perception about the importance of nutrition knowledge and nutrition information was positively correlated with nutrition knowledge (${\gamma}$:0.2, p<0.001) and nutrition attitudes (${\gamma}$:0.3, p<0.001).

• 천문학회보
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• 제37권1호
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• pp.95.2-95.2
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• 2012

We have compared the geoeffective parameters of halo coronal mass ejections (CMEs) to predict geomagnetic storms. For this we consider 50 front-side full halo CMEs whose asymmetric cone model parameters and earthward direction parameter were available. For each CME we use its projected velocity (Vp), radial velocity (Vr), angle between cone axis and sky plane (${\gamma}$) from the cone model, earthward direction parameter (D), source longitude (L), and magnetic field orientation (M) of the CME source region. We make a simple and multiple linear regression analysis to find out the relationship between CME parameters and Dst index. Major results are as follows. (1) $Vr{\times}{\gamma}$ has a higher correlation coefficient (cc = 0.70) with the Dst index than the others. When we make a multiple regression of Dst and two parameters ($Vr{\times}{\gamma}$, D), the correlation coefficient increases from 0.70 to 0.77. (2) Correlation coefficients between Dst index and $Vr{\times}{\gamma}$ have different values depending on M and L. (3) Super geomagnetic storms (Dst ${\leq}$ -200 nT) only appear in the western and southward events. Our results demonstrate that not only the cone model parameters together with the earthward direction parameter improve the relationship between CME parameters and Dst index but also the source longitude and its magnetic field orientation play a significant role in predicting geomagnetic storms.

• 대한방사선치료학회지
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• 제27권2호
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• pp.115-122
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• 2015

목 적 : 폐암환자의 비동일면 선속 빔(Non-coplanar beam) 을 이용한 방사선치료 시 HeaxPOD evo RT system(6D couch)의 정확성을 평가 하고자 한다. 대상 및 방법 : 본원에서 SBRT 환자 중 비동일면 선속 빔을 사용한 폐암환자 13명과, 동일면 선속 빔을 사용하는 폐암환자 10명을 대상으로 하였다. 대상 환자의 자세보정에 있어 Pitch, Roll, Yaw 방향에 대한 보정을 적용, 미적용으로 구분하고, 레이저(Laser)를 Arccheck(Helical grid diode detectors)의 동 중심점에 정렬시킨 후 Arccheck으로 ${\gamma}$값과 전리함(Pinpoint type chamber)을 이용하여 점 선량을 측정하였다. 평가를 위해 점 선량 측정값과 ${\gamma}$-Index(3% / 3 mm, 2% / 2 mm)를 지표로 비교분석 하였다. 결 과 : HexaPOD 미적용 시 치료계획과 비교하여 동일평면 선속 빔의 경우 ${\gamma}$-Index<1(${\gamma}=1$, 3% / 3 mm) 비율은 97.3%, 점 선량은 0.8% 의 차이를 보였다. 비 동일평면 선속 빔의 경우 각각 90.8%, 0.7%로 나타났다. HexaPOD 적용 시, 같은 조건에서 동일평면 선속 빔의 경우 각각 99.5%, 0.6%를 나타냈으며, 비 동일평면 선속 빔의 경우 각각 97.8%, 0.5%의 결과를 나타냈다. ${\gamma}$-Index<1(2% / 2 mm)의 경우, HexaPOD 미적용 시 동일평면 선속 빔의 경우 82%, 비 동일평면 선속 빔의 경우 78.3%를 나타냈으며 HexaPOD 적용 시 각각 91.2%, 93.4%의 결과가 나타났다. 결 론 : HexaPOD를 적용한 경우가 더욱 정확성이 향상되는 것을 확인할 수 있어, 고 정밀 방사선치료의 비 동일평면 선속 빔 사용 시 HexaPOD 사용이 필요할 것으로 사료된다.

• Journal of Acupuncture Research
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• 제25권6호
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• pp.47-54
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• 2008

Objectives : This study was aimed to figure out how effectively acupuncture treatment and herb-medicine work on patients with elevation of LFT value and lipid-obesity index. Methods : The subject were 23 patients visited to Dept. of Acupuncture and Moxibustion, Kwangdong Oriental Medicine Hospital, who complained chronic fatigue and wandering pain from Oct. 2007. to Oct. 2008. Before treatments, they were tested for LFT, total cholesterol, triglyceride, body fat ratio and obesity index. They were treated with Ganjeonggyeok acupuncture weekly for 1 month. During acupuncture treatments, we applied Sangkankunbi-tang to all patients twice a day. After 1 month, they were retested for LFT, total cholesterol, triglyceride, body fat ratio and obesity index. Results : 1. After treatments, we could get the result of dropping means of AST, ALT and $\gamma$-GTP value. Statistical significance of ALT and $\gamma$-GTP were recognized before and after treatments, but AST was not recognized. 2. After treatments, we also could get the result of dropping means of total cholesterol, triglyceride, body fat ratio and obesity index. Statistical significance of all values were recognized before and after treatments. 3. Among 23 patients, 10 cases were reported that they were not within normal limits at least one in AST, ALT and $\gamma$-GTP. After treatments of those patients, we could get the result of dropping means of AST, ALT and $\gamma$-GTP value. Statistical significance of all values were recognized before and after treatments. 4. Among 23 patients, 19 cases were reported that they were not within normal limits at least one in total cholesterol, triglyceride, body fat ratio and obesity index. After treatments of those patients, we could get the result of dropping means of total cholesterol, triglyceride, body fat ratio and obesity index. Statistical significance of all values were recognized before and after treatments. Conclusions : Though further study is necessary, our finding suggest that the conduction of Ganjeonggyeok acupuncture and Sangkankunbi-tang treatments have helped to decrease the figures of LFT and lipid-obesity index in patients.

• Preventive Nutrition and Food Science
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• 제13권4호
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• pp.354-361
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• 2008

A novel bacterium isolated from Cheonggukjang was identified as a glutamate-dependent Bacillus subtilis HA with 98.3% similarity to Bacillus subtilis Z99104. Optimization of poly-$\gamma$-glutamic acid ($\gamma$-PGA) production by modulating fermentation factors including carbon sources, nitrogen sources, inorganic salts and fermentation time was investigated. Optimum culture broth for $\gamma$-PGA production consisted of 3% glutamate, 3% glucose and various salts, resulting in the PGA production of 22.5 g/L by shaking culture for 72 hr at $37^{\circ}C$. Average molecular weight of $\gamma$-PGA was determined to be 1,220 kDa through MALLS analysis. The $\gamma$-PGA solution showed a typical pseudoplastic flow behavior, and a great decrease in consistency below pH 6.0 regardless of the same molecular weight of $\gamma$-PGA. The molecular weights of isolated $\gamma$-PGA were drastically decreased by heat treatment in various acidic conditions, resulting in different hydrolysis of $\gamma$-PGA. The consistency of $\gamma$-PGA solution was greatly decreased with increase heating time in acidic conditions.

• 천문학회보
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• 제40권1호
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• pp.49.3-50
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• 2015

Synchrotron radiation of relativistic electrons is an important radiation mechanism in many astrophysical sources. In the sources where the synchrotron cooling timescale is shorter than the dynamical timescale, electrons are cooled down below the minimum injection energy. It has been believed that such fast-cooling electrons have a power-law distribution in energy with an index -2, and their synchrotron radiation has a photon spectral index -1.5. On the other hand, in a transient expanding astrophysical source, such as a gamma-ray burst (GRB), the magnetic field strength in the emission region continuously decreases with radius. Here we study such a system, and find that in a certain parameter regime, the fast-cooling electrons can have a harder energy spectrum. We apply this new physical regime to GRBs, and suggest that the GRB prompt emission spectra whose low-energy photon spectral index has a typical value -1 could be due to synchrotron radiation in this moderately fast-cooling regime.

• 응용통계연구
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• 제27권1호
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• pp.103-114
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• 2014

계층적 의사결정론(AHP)에서 응답자의 신뢰성을 평가하기 위해 일관성 지수가 활용된다. 일반적으로 일관성 지수값이 0에 근접할 수록 신뢰성이 있다고 판단되나, 신뢰성에 대한 임계값은 9점 척도의 비교행렬로 부터 모의실험 된 무작위 지수의 평균에 의존한다. 본 연구에서는 9점 척도 비교행렬에 의한 모의실험 분포가 차원별로 치우침이 심한 분포라는 점에 기초하여, 차원별 일관성 지수의 분위수에 기초한 통계적 가설검정 방법을 소개하기로 한다. 그리고, 모의실험으로 계산된 일관성 지수의 분포에 따라 적절한 임계 분위값을 제공하였다. 또한, 쌍대비교행렬의 각 원소에 오차를 고려한 모형을 적용하여, 일관성 지수의 분포를 감마분포로 특수한 경우 근사시킬 수 있음을 제시하였다.

• 폴리머
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• 제30권1호
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• pp.10-13
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• 2006

의료용 등급의 폴리프로필렌 수지에 감마선을 조사한 후 내방사선성에 대한 산화방지제와 열처리의 효과에 대해 연구하였다. 폴리프로필렌과 여러 종류의 산화방지제를 혼합하고 이를 시이트 형태로 제작하여 질소분위기에서 25 kGy로 감마선 조사하였다. 감마선을 조사한 폴리프로필렌 시이트에 대해 산화방지제 종류 및 함량에 따른 색도 변화와 기계적 강도 변화를 조사하였으며 감마선 조사 후의 열처리 조건에 따른 라디칼 잔존량과 산화지수의 변화를 측정하였다. 페놀계 및 아민계 산화방지제보다는 인계 산화방지제를 폴리프로필렌에 혼합하였을 때 감마선 조사 후 색도 변화를 최소화할 수 있었다. $130\;^{\circ}C$에서 30분 동안의 열처리에 의해 산화의 원인이 되는 자유라디칼을 충분히 제거할 수 있어 열처리하지 않은 폴리프로필렌보다 낮은 산화지수를 얻을 수 있었다.