• The Journal of Pediatrics of Korean Medicine
• /
• v.19 no.1
• /
• pp.35-52
• /
• 2005

Objectives : Conclusion : The purpose of this study is to examine effect that KDKEJ used to atopic dermatitis disease patient get in atopy eruption control experimentally. Methods : We analyzed the expression of IgE, IL-6, II-4, IL-5 and IL-13's level in serum, and $IFN-{\gamma}'$ production by KDKEJ extract. We also analyzed KDKEJ extract get to NC/Nga mine's skin establishment analyzes neck-back skin after biopsy, and H&E method measured about epidermis and dermis part in comparison with control group. Results : In this research KDKEJ extract as treatment result to a NC/Nga mice, IgE and IL-6 content in serum decreased remarkably than control group. And decreased than result control group which measure II-4, IL-5 and IL-13's level in serum and $IFN-{\gamma}'$ production secreted in Th1 cell displayed increase by KDKEJ extract. IL-4 and $IFN-{\gamma}'$ gene revelation amount displayed marked decrease than control group in result that observe effect that get in skin of a NC/Nga mice's skin establishment analyzes neck-back skin after biposy, and dye by H&E method decreased about epidermis and inflammation of dermis part remarkable than control group. Conclusions : These results suggest that Th1 cell and Th2 cell observe to be shifted by secretion amount of IL-4 and $IFN-{\gamma}$ by KDKEJ extract could know that KDKEJ extract can use usefully in allergy autoimmune disease.

• Applied Chemistry for Engineering
• /
• v.28 no.3
• /
• pp.351-354
• /
• 2017

An experimental design method was used to optimize the synthesis of gamma-alumina with a superior thermal stability using the reverse micelle method. First, twelve experimental conditions were derived by using the mixture design method to optimize conditions for the ratio of surfactant, water and oil, which are main factors in the synthesis process. When the particles synthesized by reverse micelle method were calcined at $900^{\circ}C$ under the designed condition, they all had gamma-alumina crystal structure although there were differences in particle sizes. The coefficient of determination of the second-order regression model using the derived experimental results was 93.68% and the P-value was 0.002. The synthesis conditions forgamma-alumina with various particle sizes were presented using surface and contour lines. As a result, it was calculated that the smallest particle size of about 2.8 nm was synthesized when the ratio of surfactant/water/oil was 0.3450/0.0729/0.5821.

• The Korea Journal of Herbology
• /
• v.21 no.1
• /
• pp.51-56
• /
• 2006

Objectives : To clarify the effects of Actinidia polygama and CsA on OVA-induced asthma model, we examined the influence of Actinidia polygama fructus extract (APF) and CsA on the number of regulatory T cells, NKT cells and ${\gamma}{\delta}$ T cells in murine model of asthma. Methods : All mice were immunized on two different days (21 days and 7 days before inhalational exposure) by i.p. injections of OVA in PBS. Seven days after the second sensitization, mice were exposed to aerosolized ovalbumin for 30 min/day on 3 days/week for 12 weeks and APF (400, 40 mg/kg) were orally administered 3 times a week for 8 weeks. Results : The suppressive effects of APF on asthma model were demonstrated by the increase the number of regulatory T cells, ${\gamma}{\delta}$ T cells and by reducing the number of NK T cells. Conclusion : These results indicate that APF has a deep inhibitory effect on airway inflammation and hyperresponsiveness in murine model of asthma by increase the number of regulatory T cells, and ${\gamma}{\delta}$ T cells and by reducing the number of NK T cells.

• Korean Chemical Engineering Research
• /
• v.45 no.3
• /
• pp.215-218
• /
• 2007

The aim of this study is to test the feasibility of Pt/Al-MCM-41 for the dioxin decomposition reaction. For model reaction, 1,2-dichlorobenzene was decomposed instead of dioxin. $Pt/{\gamma}-Al_2O_3$ was compared with Pt/Al-MCM-41. Al-MCM-41 catlaysts were prepared by post grafting method and the Pt/Al-MCM-41 catalysts with Si/Al = 15, 30 showed higher catalytic activity than $Pt/{\gamma}-Al_2O_3$. Their higher catalytic activities were related with acid amounts. Especially Al-MCM-41 with ion exchanged with $H^+$ enhanced catalytic activity.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.20 no.1
• /
• pp.58-64
• /
• 2006

The purpose of this study is to examine closely effect that YKS used to atopic dermatitis disease patient get in atopy eruption control experimentally. We analyzed the expression of IgE, IL-6, IL-4, IL-5 and IL-13's level in serum, and IFN-${\gamma}'$ production by YKS extract. We also analyzed YKS extract get to NC/Nga mice's skin establishment analyzes neck-back skin after biopsy, and H&E method measured about epidermis and dermis part in comparison with control group. In this research YKS extract as treatment result to a NC/Nga mice, IgE and IL-6 content in serum decreased remarkably than control group. And decreased than result control group which measure IL-4, IL-5, IL-13's level in serum, and IFN-${\gamma}'$ production secreted in Th1 cell displayed increase by YKS extract. IL-4 and IFN-${\gamma}'s$ gene revelation amount displayed marked decrease than control group in result that observe effect that get in skin of a NC/Nga mice. Also, In culture supernatant which cultivate for 14 day after separate skin cell, IL-13 and IL-6 production decreased than control group. YKS extract get to NC/Nga mice's skin establishment analyzes neck-back skin after biopsy, and dye by H&E method decreased about epidermis and inflammation of dermis part remarkably than control group. These results suggest that Th1 cell and Th2 cell observe to be shifted by secretion amount of IL-4 and IFN-$\gamma$ by YKS extract could know that YKS extract can use usefully in allergy autoimmune disease.

• Journal of Radiation Industry
• /
• v.6 no.1
• /
• pp.23-29
• /
• 2012

In this study, we investigated the genetic variation in the general of monocot model plant (rice) in response to various ionizing irradiations including gamma-ray, ion beam and cosmic-ray. The non-irradiated and three irradiated (200 Gy of gamma-ray and 40 Gy of ion beam and cosmic-ray) plants were analyzed by AFLP technique using capillary electrophoresis with ABI3130xl genetic analyzer. The 29 primer combinations tested produced polymorphism results showing a total of 2,238 bands with fragments sizes ranged from 30 bp to 600 bp. The number of polymorphism generated by each primer combinations was varied significantly, ranging from 2 (M-CAC/E-ACG) to 158 (M-CAT/E-AGG) with an average of 77 bands. Polymorphic peaks were detected as 1,269 with an average of 44 per primer combinations. By UPGMA (Unweighted Pair Group Method using Arithmetic clustering) analysis method, the clusters were divided into non-irradiated sample and three irradiated samples at a similarity coefficient of 0.41 and three irradiation samples was subdivided into cosmic-ray and two irradiation samples (200 Gy of gamma-ray and 40 Gy of ion beam) at similarity coefficient of 0.48. Similarity coefficient values ranged from 0.41 to 0.55.

• Journal of the Korean Society of Propulsion Engineers
• /
• v.16 no.4
• /
• pp.33-41
• /
• 2012

The aim of the study is to investigate the method to estimate a shelf life of KM6 single base propellant by stochastic gamma process model. The state failure level is assumed that the degradation content of stabilizer is below 0.8%. The constant of time dependent shape function and the scale parameter of stationary gamma process are estimated by moment method. The state distribution at each storage time can be shown from probability density function of deterioration. It is estimated that the $B_{10}$ life, a time at which the cumulative failure probability is 10%, is 25 years and the $B_{50}$ life is 36 years from cumulative failure distribution function curve. The $B_{50}$ life can be treated as the average shelf life from the practical viewpoint and the lifetime can be expressed as distribution curve by using stochastic process theory.

• Proceedings of the Korean Society of Broadcast Engineers Conference
• /
• 2015.07a
• /
• pp.78-80
• /
• 2015

광적응(Luminance Adaptation; LA) 효과는 영상의 배경 밝기에 따른 왜곡에 대한 시각 인지 민감도가 달라지는 특성을 의미한다. 기존 영상 화질 측정(Image Quality Assessment; IQA) 방법들은 베버의 법칙(Weber' s law) 모델을 이용하여 LA 효과를 IQA 방법에 반영해왔다. 그러나, 이러한 IQA 방법들에 있어서 베버의 법칙 기반 LA 효과 모델은 다음 두 가지 이유로 부정확하게 동작한다: (i) 전통적인 베버의 법칙 모델은 실제 광도(luminance)에 대한 인지 민감도 응답값을 정확히 반영할 수 없다는 것이 밝혀졌다, (ii) 대부분 IQA 방법들은 픽셀 강도 영역에서 계산되지만, 베버의 법칙과 같은 LA 효과 모델들은 광도 영역에서 개발되었다. 따라서 광도와 픽셀 강도간 비선형 관계로 인해 IQA 방법에 반영된 베버의 법칙 기반 LA 효과 모델들은 부정확하게 동작한다. 이 문제를 해결하기 위해, 본 논문에서 처음으로 픽셀 강도 영역에서의 LA 모델을 이론적으로 유도한다. 본 논문에서 제안하는 픽셀 강도 영역에서의 LA 효과 모델은 감마 교정 함수(Gamma correction function)와 광도 영역에서의 LA 효과 모델인 제곱-법칙(power-law) 모델을 기반으로 하는 테일러 급수 확장 근사화를 통해 유도된다. 제안하는 픽셀 강도 영역 LA 효과 모델의 효과를 검증하기 위해, 제안하는 LA 효과 모델을 PSNR 에 도입하여 광범위한 실험을 수행한다. 실험 결과, 제안하는 LA 효과 모델 기반 PSNR 은 PSNR 및 베버의 법칙 기반 PSNR 대비 괄목할 만한 주관적 화질 예측 성능 향상을 보였다.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.16 no.4
• /
• pp.416-422
• /
• 2006

Most of the existing statistical models of software manpower profile are based on the assumptions of the usage and development process. Therefore, there is no universally applicable estimation and prediction model. To develop a prediction model, this paper suggests the predictive filter as a prediction model for software manpower profile. Firs of all, we investigate the software manpower profile and we suggest the input-output of predictive filter and method for parameter determination. Then, its usefulness is empirically verified by analyzing the actual data obtained from the software projects. Based on the average relative prediction error and Pred(0.25), the suggested predictive filter is compared with other well-known statistical estimation models. As a result, the predictive filter generally has a simple structure and on the other hand, it adapts the software manpower profile very well.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2022.05a
• /
• pp.200-200
• /
• 2022

본 연구에서는 총 강우량과 강우강도을 고려한 이변수 분석으로 연최대 호우사상을 선별하고, 두 변수를 Copula 함수로 결합하여 최적의 모델조합을 찾는 확률호우사상 산정 방법론을 제시하였다. 국내 69개 관측소의 2020년까지의 관측 자료를 대상으로 1mm 이하의 강우는 제거한 뒤, IETD(Inter-Event Time Definition) 12시간을 기준으로 강우자료를 독립적인 호우사상으로 분리하였다. 호우사상의 여러 특성 중 양의 상관관계를 갖는 총 강우량과 강우강도를 변수로 선택해 이변수 지수분포에 대입하였고, 각 지점의 연최대 호우사상 시계열을 생성하였다. 2변수 지수분포의 매개변수는 전체 기간과 연도별로 나누어 추정해 본 결과 연도별 변동성이 큰 것을 확인해 연도별 추정 방식을 선택하였다. 연최대 강우사상 시계열의 총 강우량과 강우강도는 극한 강우에 적용하는 확률분포형 중 Lognarmal, Gamma, Gumbel, GEV(Generalized Extreme Value), GPD(Generalized Pareto Distribution) 5가지를 사용하여 각각 CDF(Cumulative distribution Function) 값을 추정하였다. 계산된 CDF 값은 3가지 Copula 모형으로 결합해 joint CDF 값을 산출하였다. 총 75개의 모델조합 중 최적 모델을 찾기 위해 CVM(Cramer-von-Mises) 적합도 검정을 시행하였다. CVM의 통계량 Sn 값이 가장 작은 모델조합을 해당 지점의 최적 모델조합으로 선정하였다.