• Title/Summary/Keyword: Gallic Acid

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Free Radical Scavengers from the Fruits of Paeonia suffruticosa

  • Lee, Sa-Im;Yang, Jae-Heon;Baek, Nam-In;Kim, Sung-Hoon;Cho, Chong-Hyeon;Park, Byung-Hyun;Chae, Byeong-Suk;Kim, Dae-Keun
    • Natural Product Sciences
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    • v.14 no.3
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    • pp.202-205
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    • 2008
  • The antioxidant activity of Paeonia suffruticosa (Paeoniaceae) was determined by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl). The methanolic extract of P. suffruticosa showed the strong antioxidant activity. The antioxidant activity of ethyl acetate soluble fraction was stronger than that of the others ($IC_{50}$, $1.2\;{\mu}g/mL$), and the fraction was subjected to purification by repeated silica gel and Sephadex LH-20 column chromatography. Suffruticosol A, suffruticosol B, methyl gallate, and gallic acid, were isolated from the ethyl acetate soluble fraction. Their structures were elucidated by physico-chemical and spectroscopic studies.

Hydrolyzable Tannins from the Fruits of Rubus coreanum (복분자 딸기 열매의 가수분해성 탄닌)

  • Pang, Keun-Cheol;Kim, Min-Son;Lee, Min-Won
    • Korean Journal of Pharmacognosy
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    • v.27 no.4
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    • pp.366-370
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    • 1996
  • Fruits of Rubus coreanum (Korean name: Bog-bun-ja) have been used in oriental traditional medicine as the remedies for impotence, pollution, premature ejaculation and frequency of urination etc. It is known to have phenolic compounds as an astringent. By means of chromatographic methods, four hydrolyzable tannins were isolated from the fruits of R. coreanum. The structures of these compounds were established as gallic acid, 2,3(S)-HHDP-D-glucopyranose, sanguiin H-4 and sanguiin H-6 on the basis of physicochemical and spectroscopic evidences.

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Phenolic Compounds from Stems of Securinega suffruticosa (광대싸리 줄기의 페놀성 화합물)

  • Lee, Sang-Cheol;Ahn, Byung-Tae;Park, Woong-Yang;Lee, Seung-Ho;Ro, Jai-Seup;Lee, Kyong-Soon
    • Korean Journal of Pharmacognosy
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    • v.27 no.1
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    • pp.1-5
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    • 1996
  • Twelve compounds were isolated from stems of Securinega suffruticosa. On the basis of chemical and spectroscopic evidence, they were identified as gallic acid, corilagin, tercatain, geraniin, bergenin, norbergenin, 4-O-galloylnorberg-enin, 11-O-galloylnorbergenin, (+)-catechin, gallocatechin, isoquercitrin and rutin.

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Ingredients of Antioxidant Activity from Calyx of Diospyros kaki Thunberg (감꼭지의 항산화 활성 성분)

  • Cha, Bae Cheon
    • Korean Journal of Pharmacognosy
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    • v.45 no.1
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    • pp.35-40
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    • 2014
  • In this study, in order to search for new functional materials from natural products, was carried out the study of antioxidant active ingredients in persimmon calyx(calyx of Diospyros kaki Thunberg). I have experimented with the effect of antioxidant activity of five different extract(MeOH, n-hexane, EtOAc, n-BuOH and $H_2O$ extract) obtained from persimmon calyx. As a result, the butanol extract, that is the main component fraction of antioxidant activity was found. Three compounds were isolated by silica gel column chromatography from the n-BuOH extract of persimmon calyx. Their structures of compound 1, 2 and 3 isolated from n-BuOH extract of persimmon calyx were identified as quercetin, (+)-catechin and gallic acid by using the TLC, $^1H$-NMR and $^{13}C$-NMR.

Phenolic Components from the Leaves of Cornus controversa H. (층층나무 잎의 Phenol성 성분 (I))

  • Lee, Dong-Ho;Lee, Seung-Ho;Chung, See-Ryun;Ro, Jai-Seup;Lee, Kyong-Soon
    • Korean Journal of Pharmacognosy
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    • v.26 no.4
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    • pp.327-336
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    • 1995
  • Twelve phenolic components were isolated from the aqueous acetone extract of the leaf of Cornus controversa H. (Cornaceae). On the basis of chemical and spectroscopic evidence, the structures of these components were established as gallic acid, $1-O-galloyl-{\beta}-{_D}-glucose$, $1,6-di-O-galloyl-{\beta}-{_D}-glucose$, $1,2,3-tri-O-galloyl-{\beta}-{_D}-glucose$, $1,2,6-tri-O-galloyl-{\beta}-{_D}-glucose$, 3,4,6-tri-O-galloyl ${_D}-glucose$, eugeniin, gemine D, quercetin, quercitrin, hyperoside and rutin.

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The Phenolic Constituents of Phyllanthus ussuriensis Leaves(I) (여우주머니 잎의 Phenol성 성분(I))

  • Whang, Wan-Kyunn;Oh, In-Se;Ham, In-Hye;Hahn, Dug-Ryong
    • Korean Journal of Pharmacognosy
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    • v.25 no.2
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    • pp.113-116
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    • 1994
  • For the investigation of medicinal resource in Phyllanthus ussuriensis, the studies were conducted to evaluate the pharmaco-constituents in Phyllanthus ussuriensis, which is used as folk medicine in China. From the hot water extract of leaves, three phenolic compounds were isolated and identified as phloroglucinol, gallic acid and rutin by physico-chemical properties and spectroscopic evidences$(IR,{\;}^1H-NMR,{\;}^{13}C-NMR{\;}and{\;}Mass,{\;}etc.)$.

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Chemical Components from the Stem Bark of Cornus controversa $H_{EMSL}$ (층층나무 수피의 성분)

  • Jang, Hyun-Min;Hwang, Bang-Yeon;Kim, Min-Soo;Lee, Dong-Ho;Kang, Shin-Jung;Ro, Jai-Seup;Lee, Kyong-Soon
    • Korean Journal of Pharmacognosy
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    • v.29 no.3
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    • pp.225-230
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    • 1998
  • Cornus controversa $H_{EMSL}$. (Cornaceae) is distributed widely in Korea and has been used for the treatment of diarrhea and a tonic medicine. Six compounds were isolated from the MeOH extract of the dried stem bark of Cornus controversa. Their structures were identified as gallic acid(1), scopoletin(2), arjunglucoside II(3), isoquercitrin(4), quercitrin(5) and rutin(6) by comparisons of the physicochemical and spectroscopic evidences. Among these compounds, scopoletin and arjunglucoside II were the first time isolation from this plant.

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Phenolic Compounds from the Stem Bark of Cornus walteri Wanger (말채나무 수피의 페놀성 화합물)

  • Choi, Woo-Hoi;Park, Woong-Yang;Hwang, Bang-Yeon;Oh, Gap-Jin;Kang, Shin-Jung;Lee, Kyong-Soon;Ro, Jai-Seup
    • Korean Journal of Pharmacognosy
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    • v.29 no.3
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    • pp.217-224
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    • 1998
  • Eight compounds were isolated from the stem bark of Cornus walteri. On the basis of chemical and spectroscopic evidences, the structures of these compounds were identified as gallic acid, (+)-gallocatechin, (+)-catechin, quercetin, quercitrin, rutin, isoquercitrin and hyperoside respectively.

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Electron Donating Ability of MeOH Extracts from Three Korean Mistletoes

  • Choi, Won-Sil;Ahn, Won-Yung
    • Journal of the Korean Wood Science and Technology
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    • v.28 no.4
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    • pp.1-9
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    • 2000
  • This experiment was accomplished to investigate antioxidative activity of Korean mistletoe by organic solvents partitioning of methanol extact of 3 Korean mistletoes, fractionationing on column chromatography, and evaluation the reduction of a free radical ${\alpha}$,${\alpha}$-diphenyl-${\beta}$-picrylhydrazyl. Butanol partition of Loranthus yadoriki MeOH extract showed higher electron donating ability than ${\alpha}$-tocopherol. It was thought phenolic compounds including gallic acid account for antioxidative activity, on execution sub-fractionation, electron donating ability evaluation, and GC/MS analysis, but further studies on what are major actives must be investigated exactly.

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Antioxidant and Acetylcholinesterase Inhibition Activity of Mulberry Fruit Extracts

  • Lee, Young-Ju;Lee, Ka-Hwa;Ahn, Chang-Bum;Chun, Soon-Sil;Je, Jae-Young
    • Food Science and Biotechnology
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    • v.18 no.6
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    • pp.1532-1536
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    • 2009
  • The objective of this study was to evaluate the antioxidant effects and acetylcholinesterase (AChE) inhibition activity of mulberry fruit extracts prepared by hot water (MFH) and 80% ethanol (MFE). Total polyphenolic contents of MFH and MFE were $195{\pm}3.4\;mg$ gallic acid equivalents/g MFH and $185{\pm}2.8\;mg$ gallic acid equivalents/g MFE. MFH and MFE significantly quenched 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydrogen peroxide dose-dependently, and showed high chelating ability and reducing power in non-cellular systems. MFH and MFE also inhibited the formation of intracellular reactive oxygen species and lipid peroxidation, and elevated intracellular glutathione (GSH) levels in RAW264.7 cells. In addition, MFH and MFE also dose-dependently suppressed AChE activity.