• Title/Summary/Keyword: GabD

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Role of Spinal Adenosine $A_2$ Receptor in the cardiovascular Regulation in Rats (흰쥐에서 실혈관 조절기전에 대한 척수의 Adenosine $A_2$수용체의 역할)

  • 문삼영;신현진;신인철;고현철;엄애선;박정로;김범수;강주섭
    • Biomolecules & Therapeutics
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    • v.8 no.4
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    • pp.325-331
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    • 2000
  • The present study was designed to assess the role of spinal adenosine $A_2$ receptor in the regulation of cardiovascular functions such as mean arterial pressure (MAP) and heart rate (HR) in male Sprague-Dawley rats. Rats (250~300 g) were anesthetized with urethane and paralyzed with d-tubocurarine and artificially ventilated. blood pressure and HR were continuously monitored via a femoral catheter connected to a pressure transducer and a polygraph. Drugs were administered intrathecally using injection cannula through guide cannula which was inserted inthrathecally at lower thoracic level through a puncture of an atlantooccipital mombrane. Intrathecal injection of an adenosine $A_2$ receptor agonist, 5'-(N-cyclopropyl)-carboxamaidoadenosine (CPCA; 1, 2 and 3 nmol, respectively), produced a dose-dependent decrease in MAP and HR. Pretreatment with $N^{G}$-nitro-L-arginine methyl ester (L-NAME), a nitric oxide synthase inhibitor or 10 nmol of MDL-12,330, an adenylate cyclase inhibitor blocked significantly the depressor and bradycardic effect of 2 nmol of CPCA. But, Pretreatment with 3 nmol of bicuculline, gamma-aminobutyric acid A (GAB $A_{A}$) receptor antagonist, or 50 nmol of 5-aminovaleric acid, GAB $A_{B}$ receptor antagonist did not inhibit the depressor and bradycardic effect of 2 nmol of CPCA. These results indicate that adenosine $A_2$ receptor in the spinal cord plays an inhibitory role in the regulation of cardiovascular function and that the depressor and bradycardic action of adonosine $A_2$ receptor are mediated via the synthesis of nitric oxide and the activation of adenylate cyclase in the spinal cord of rats.s.s.s.

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The influence of transom pipe gap on the resonance response in motorized bogie and traction motor system (트랜섬 파이프 간격이 동력대차-견인전동기간 강체 모드 공진응답에 미치는 영향에 관한 연구)

  • Kim, Jaehwan;Song, Seeyeop;Lim, Hyosuk
    • The Journal of the Acoustical Society of Korea
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    • v.38 no.3
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    • pp.340-343
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    • 2019
  • In this paper, a problem of mechanical resonance between traction motor's rigid body mode and traction motor's excitation force is introduced, and a bogie design variable affecting the control of resonance response is reviewed numerically. To solve the resonance problem in rotating machinery with variable rotational speeds, resonance frequency should be out of rotational machine's operation range or dynamic stiffness of structures should be increased for resonance response enough to be low. In general, operation range of a traction motor is from 0 r/min to 4800 r/min. It is not possible that all bogie modes are more than 80 Hz. Therefore, it is very important to find design factor affecting resonance response of traction motor's rigid body modes. It is found that key design variable is the gab between transom pipes from finite element analysis. The larger gab is, the higher resonance response when resonance between traction motor's excitation force and traction motor's rigid body mode is happened.

Optical true time-delays for phased-array antennas using 2×2 MEMS switches and fiber delay lin (2×2 MEMS 스위치와 광섬유 지연선로를 이용한 위상배열 안테나용 실시간 지연선로)

  • Lee, Gab-Yong;Choi, Yeon-Bong;Shin, Jong-Dug;Kim, Boo-Gyoun
    • Korean Journal of Optics and Photonics
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    • v.13 no.4
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    • pp.289-294
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    • 2002
  • We propose optical true time-delays (TTDs) for phased-array antennas (PAAs) composed of 2${\times}$2 MEMS switches and fiber delay lines, and implement a TTD which shows a maximum scan angle of $120^{o}$ with $30^{o}$ resolution. Since this structure uses only one fixed wavelength laser diode, it provides several advantages such as easy control, high speed operation, and low cost compared with those of the optical TTDs using tunable laser sources. We design a four element linear PAA using the proposed TTDs at 10 ㎓. Simulation results show that the maximum gain is 11.6 dB at the radiation angle $0^{o}$, 11.2 dB at $\pm$$30^{o}$, and 10.6 dB at $\pm$$60^{o}$.

Ultrasonic Target Strength of Cyprinus Carpio in Accordance with Body Length and Body Weight (이스라엘 잉어 Cyprinus Carpio의 체장 , 체중별 초음파 표적강도에 관한 연구)

  • Shin, Hyoung-Ho;Yoon, Gab-Dong;Park, Hae-Hoon
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.25 no.4
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    • pp.191-199
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    • 1989
  • Research on the acoustic properties of fish has been carried out by a number of scientific workers from the earliest days of applying acoustic techniques to fish biomass estimates. This paper describes measurements of the target strength of Cyprinus Carpio, which measurements made at 50KHz in the experimental water tank. The results obtained are as follows: 1. The target strength(dB) of the fish has a directivity pattern quite similar to that of a transducer. The maximum value of target strength(dB) is obtained when the fish is insonified to its head-tail axis either from the dorsal or from the ventral side. 2. Empirical relationship between target strength(dB) and body length(cm) of the fish can be estimated as TS=20 Log L-65.4 where TS is the target strength of the fish and L is the body length of the fish. 3. The relationship between target strength(dB) and body weight(g) of the fish can be estimated as TS=6.7 Log W-53.7 where W is body weight of the fish.

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The Under Water Ambient Noise at Voting-il Bay (영일만 부근에서의 수중소음)

  • HA Kang Lyeol;YOON Gab Dong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.16 no.3
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    • pp.197-201
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    • 1983
  • Underwater ambient noise level was measured at two points near the Youngil Bay. The environmental characteristics depend upon oceanographic conditions of sound propagation ana its implication on the source of ambient noise. Some noise sources were estimated, and the effect of the oceanographic conditions on the noise level variation had been considered. The results were as follows : 1) At the nearshore station of Youngil Bay, the ambient noise level in the near bottom(45m) was lower than that of the near surface(10m) by 15dB. This difference was due to spherical spreading from the upper to the lower layer. 2) At the open sea station which is located outside of the thermal front existing near the Youngil Bay, the ambient noise level of the upper layer(20m) was higher than that of the lower layer (100m) by $8{\sim}12dB$ below 50Hz and $15{\sim}23dB$ above 50Hz. 3) Above 60Hz the ambient noise level at the nearshore station was higher than that of the open sea station, while below 60Hz, the result was reverse. It appears that a boundary layer existed between the two stations.

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Mutivariate Analysis on Quantitative Characteristics of Prunus mume (매실의 다변량에 의한 양적 형질 분석)

  • Choi, Gab Lim;Hyun, Kyu-Hwan;Shin, Dong Young
    • Korean Journal of Plant Resources
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    • v.27 no.1
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    • pp.89-94
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    • 2014
  • Varietal distances were measured by Mahalanobis's $D^2$ statistics in 190 possible comparisons among twenty varieties of Prunus mume with twelve characters such as seed weight, length, width, and diameter, fruit weight, and number of sepals, petals, pistils, and stigmas, and leaf length and width. A complete linkage cluster analysis based on the Mahalanobis's distance ($D^2$) was attempt. Twenty varieties of Prunus mume were largely classified into five subgroups. Group I, II, III, IV and V included two, four, five, five and four varieties, respectively. Most of the varietal groups were not associated with their geographical origins. Number of stigmas, and leaf length and width among the twelve characters were the largest contributors to the $D^2$ in both intra-and inter groups.

The Design and Implementation of Frequency Domain Sampling Method for Surface Acoustic Wave Sensor Platform (주파수 영역 샘플링 방식의 표면 탄성파 센서 플랫폼 설계 및 구현)

  • Sun, Hee-Gab;Joh, Yool-Hee;Kim, Young-Kil
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.17 no.1
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    • pp.218-224
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    • 2013
  • Generally, SAW device, which uses Time Domain Sampling, requires high speed A/D converter because SAW device using TDS needs high sampling speed as much as its high data speed. However, the high price of A/D converter discourages makers from using it. On the other hand, SAW device, which uses Frequency Domain Sampling, does not required high speed A/D converter because SAW device using FDS does not need high sampling speed. It is very efficient in price comparison to its performance because high processing speed of SAW device using FDS can be implemented using low price Embedded Systems. The purpose of the paper is to solve the issues above by designing and realizing SAW device(FDS) using SAW sensor for TDS.

Analysis of the 3-D Stress Wave in a Plate under Impact Load by Finite Element Method

  • Jin, Sung-Hoon;Hwang, Gab-Woon;Cho, Kyu-Zong
    • International Journal of Precision Engineering and Manufacturing
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    • v.2 no.2
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    • pp.5-10
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    • 2001
  • This paper attempt to explore the shape of stress wave propagation of 3-dimensional stress field which in made in the process of the time increment. A finite element program about 3-dimensional stress wave propagation is developed for investigating the changing shape of the stress by the impact load. The finite element program, which is the solution for the 3-dimensional stress wave analysis, based on Galerkin and Newmark-${\beta}$ method at time increment step. The tensile stress and compressive stress become larger with the order of the middle , the upper and the opposite layers when the impact load is applied. In a while the shear stress become larger according to the order of the upper, the middle and the opposite layers when impact load applied.

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A Design and Fabrication of a 0.18μm CMOS Colpitts Type Voltage Controlled Oscillator with a Cascode Current Source (0.18μm NMOS 캐스코드 전류원 구조의 2.4GHz 콜피츠 전압제어발진기 설계 및 제작)

  • Kim, Jong-Bum;You, Chong-Ho;Choi, Hyuk-San;Hwang, In-Gab
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.12
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    • pp.2273-2277
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    • 2010
  • In this paper a 2.4GHz CMOS colpitts type microwave oscillator was designed and fabricated using H-spice and Cadence Spetre. There are 140MHz difference between the oscillation frequency and the resonance frequency of a tank circuit of the designed oscillator. The difference is seemed to be due to the parasitic component of the transistor. The inductors used in this design are the spiral inductors proposed in other papers. Cascode current source was used as a bias circuit of a oscillator and the output transistor of the current source is used as the oscillation transistor. A common drain buffer amplifier was used at the output of the oscillator. The measured oscillation frequency and output power of the oscillator are 2.173GHz and -5.53dBm.

The Effects of Meridian Acupressure on Decreasing Constipation for Stroke Patients (경혈지압이 뇌졸중 환자의 변비완화에 미치는 효과)

  • Lee, Gab Nyea;Shon, Kyung Hee
    • Korean Journal of Adult Nursing
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    • v.18 no.5
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    • pp.760-770
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    • 2006
  • Purpose: This study was aimed at identifying the effect of meridian acupressure on decreasing the severity of constipation in stroke patients admitted to the intensive care unit. Method: The data was collected from June 1 to July 30, 2005 at D Hospital in Busan. They were divided into two group: one experimental group of 18, and the another control group of 17. Meridian acupressure was given to the experimental group and no meridian acupressure was given to the control group. The data was analyzed using the t-test, ${\chi}^2-test$, Fisher exact, and repeated measures ANCOVA. Results: There was a significant improvement in frequency of defecation and severity of constipation in the experimental group compared to the control group. Conclusion: Meridian acupressure can be considered an effective nursing method for the management of constipation among Cerebrovascular Accident patients.

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