• Korean Journal of Acupuncture
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• v.29 no.3
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• pp.467-475
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• 2012

Objectives : The aim of this study was to examine the effects of Acupuncture at the GV20 and GV22 on normal human beings using power spectrum analysis. Methods : Electroencephalogram(EEG) power spectrum exhibits site-specific and state-related differences in various frequency bands. 8 channels Background Electroencephalogram (EEG) was carried out in 30 subjects(24 females and 4 males). Results : In ${\delta}$(theta) band, the power values decreased significantly at the 8-channel average value(p=0.03) and especially at T3(p=0.02), T4(p=0.001) and P3(p=0.03). In ${\alpha}$(alpha) band, the power values have no significant changes. In ${\beta}$(beta)band, the power values increased significantly at the 8-channel average value (p=0.02) and especially at T4(p=0.003), P3 (p= 0.03) and P4(0.02). In ${\beta}/{\delta}$(beta/theta) ratio, the value increased significantly at the 8-channel average value(p=0.002) and especially at Fp2(p=0.05), F4(p=0.007), T3(0.012), T4(0.005), P3 (0.007) and P4(0.03) Conclusions : Through this data, we conclude that acupuncture at the GV20 and GV22 on normal human beings could have possibility to awake the cerebral cortex by the functional mechanism.

• Korean Journal of Acupuncture
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• v.38 no.1
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• pp.8-15
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• 2021

Objectives : This study was conducted to explain the locations of GV24, BL4, GB15, GB13, and ST8 from classic literatures. Methods : 17 classics of acupuncture and moxibustion literature - 『Huangdimingtangjingjixiao』, 『Zhenjiujiayijing』, 『Huangdimingtangjiujing』, 『Beijiqianjinyaofang』, 『Qianjinyifang』, 『Waitaimiyaofang』, 『Ishimpo』, 『Taipingshenghuifang』, 『Tongrenshuxuezhenjiutujing』, 『Zhenjiuzishengjing』, 『Shisijingfahui』, 『Zhenjiujuying』, 『Yixuerumen』, 『Zhenjiudacheng』, 『Leijingtuyi』, 『Chimgukyungheombang』 and 『Yizongjinjian』 - were reviewed and compared. Results : Location of GV24 was on the midpoint of the anterior hairline before Song Dynasty, but changed to 0.5 cun directly above the midpoint of the anterior hairline after Song Dynasty. The locations of BL4, GB13 and ST8 varied among literatures. Conclusions : The locations of GV24, BL4, GB15, GB13 and ST8 were different from the standard acupoint locations, and were not consistent in 17 acupuncture and moxibustion classic literatures.

• Korean Journal of Acupuncture
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• v.26 no.3
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• pp.13-25
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• 2009

Objectives : This study was performed to investigate acupoints and muscles used for cosmetic acupuncture. We want most clinicians practicing cosmetic acupuncture to understand theoretical background well and to treat cosmetic diseases more diversely by this paper. Methods : We collected useful informations from some books and websites about cosmetic acupuncture and thus could select major acupoints and muscles. Conculsions : The most frequently used acupoints for cosmetic acupoints are as follows ; LI20, ST1, ST2, ST3, ST4, ST5, ST6, ST7, ST8, SI18, SI19, BL1, BL2, BL3, BL4, TE17, TE18, TE19, TE20, TE21, TE22, TE23, GB1, GB2, GB3, GB4, GB5, GB6, GB7, GB8, GB13, GB14, GV20, GV21, GV22, GV23, GV24, GV25, GV26 and CV24. And head and neck muscles including SCM muscle, plastyma, frontalis, corrugator supercilii, orbicularis oculi, auricularis, temporalis, masseter, pterygoid, zygomaticus and risorius can be used for cosmetic acupuncture. Most acupoints and muscles are located in face and head, which seemed to be concerned with formation of face wrinkles.

• Journal of Acupuncture Research
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• v.18 no.5
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• pp.147-154
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• 2001

Amun(GV15), Habkook(LI4) and Shinsu(B23) have been used as a meridian point for apoplexy, hypertention, vertigo etc. The effects of GV 15, LI4 and B23 on the vascular system is not known. The purpose of this Study was to investigate the effect of several meridian points on the regional cerebral bloof flow(rCBF), mean arterial blood pressure(BP) in rats. The changes of BP and rCBF were tested Laser-Doppler Flowmetry(LDF). Results : The results of this Study were obtained as follows ; 1. GV15 and LI4 were increased significantly rCBF. 2. GV15, LI4 and B23 were increased BP, but have not significance. Conclusion : This results suggest that GV15 was increased rCBF by increasing pial arterial diameter, and LI4 was increased rCBF by increasing BP.

• Journal of Veterinary Clinics
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• v.24 no.4
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• pp.608-612
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• 2007

A 4-year-old castrated male Cocker spaniel was referred with chief complaint of pelvic limbs paralysis and trembling. This dog was diagnosed as a case of myelomalacia complicated with intervertebral disc disease(IVDD) by radiography and magnetic resonance imaging(MRI). This patient was treated by injection-AP with apitoxin, herbal medicine and moxibustion. The acupoints such as GV02-1, GV04, GV11, GV12, GV13, GV14, BL11, BL18, BL23, BL25, BL28, GB21, HT07, KI03, LI04, LU07, SI03, SI06, ST36, ST38, ST39, ST40, ST41, GB30, GB31, GB34, Liv03, SP06 and trigger points($T1{\sim}T4\;and\;T9{\sim}L1$) were used for treatment. At the session 1, the dog could not stand and move the limbs. However, gradual improvement of clinical signs was observed after 7, 14 and 21 session of treatment. Although the clinical signs related to pelvic paralysis were not completely abolished with TVM methods, this case showed the marked improvement of clinical signs after 21 sessions of treatment. In conclusion, the present patient was a case with canine myelomalacia complicated with IVDD which showed not so complete but somewhat improvement by TVM method.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.211-211
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• 1994

항종양성 화합물의 개발을 지향한 해양생물 유래의 생물활성 물질의 화학적 연구의 일환으로써 다양한 종류의 생물활성 (즉, 항균작용, 혈중콜레스테롤 저하작용)등을 나타내며, 구입수가 용이한 홍조 꼬시래기 (Gracilaria verrucosa) 및 갈조 지충이 (Sargassum thunbergii)의 아세톤 및 메탄올 엑스를 EtOAc 및 n-BuOH로 분획한후 각 분획을 SiO$_2$ column, TSK gel(Toyo pearl HW-40F), $\mu$-Bondapak column 및 HPLC등으로 분리 정제하여, 새로운 glyceroglycolipid(GV-5, -6, ST-6) 및 glycerylglycoside(GV-12)를 얻었다. 이렇게 분리된 화합물의 물리화학적 성질, 화학반응 및 분광학적 data를 종합 검토한 결과 GV-5, -6, -12, 및 ST-6은 각각 1,2-diacyl-3-0-($\alpha$-D-galactopyranosyl) glycerol (acyl : palmitate-oleate-arachidonate 4: 1 : 9) (1), 1,2-diacyl -3-0-〔$\alpha$-D-galactopyranosyl -(1 "$\longrightarrow$6')-0-$\beta$-D-galactopyranosyl〕 glycerol (acyl : palmitate-oleate-arachidonate(5:1:4)(3), 2-0-($\alpha$-D-galactopyranosyl) glycerol (5), 및 sodium salt of 1-acyl-3-0-(6'-sulfo-$\alpha$-D-quinovopyranosyl) glycerol(acyl:palmitate-oleate 96:4)(8) 이라는 것이 판명되었다. 그리고 GV-5 및 -6은 마우스 백혈병세포 (L1210)에 대한 세포독성 ($IC_{50}$/ of GV-5, and -6:8.0$\mu\textrm{g}$/ml and 10.8$\mu\textrm{g}$/ml )외에, 사람의 상피암세포에 대한 성장억제효과 [growth inhibitor(%) in 20$\mu\textrm{g}$/m1 :GV-5(39.9%), GV-6(16.7%)를 나타내었으며, 한편, GV-5, GV-6, -12 및 ST-6은 각각 쥐의 F9 기형암종 세포의 분화유도 활성을 나타내어 항종양제로의 개발에 많은 흥미가 기대된다.기대된다.

• Journal of Haehwa Medicine
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• v.10 no.1
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• pp.471-482
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• 2001

Infantile Convulsion, one of common emergency symptoms in pediatrics, arises from sudden derangement of the central nerve system, and can cause a sudden loss of consciousness and spasm. It falls into three categories: Acute Infantile Convulsion, Chronic Infantile Convulsion and Chronic Spleen Convulsion. According to research, approximately 6~7% of all babies undergo spasm more than once. Since the treatment must be done immediately, acupuncture & moxibustion treatment can be one of the most important treatments in this Particular case. Therefore, the focus of this study is on how acupuncture & moxibustion can be utilized in the treatment of Infantile Convulsion, and the literary findings are as follows: 1. The meridian points used on acute infantile convulsion are Sugu(GV26), T'aech'ung(Liv3), Hapkok(LI4). 2. The meridians used on acute infantile convulsion are Governor Vessel(GV), Bladder Meridian(BL), Stomach Meridian(ST). 3. The meridian points used on accompanied symptoms with acute infantile convulsion are Haenggan(Liv2), Yangnungch'on(Liv3) on spasm, Paek'oe(GV14) on opisthotonus, Kokchi(LI11), Taech'u(GV14) on fever, Nogung(P8), Yongch'on(K1) on fainting spell, Chok-samri(S36) on body weakness. 4. The meridian points used on chronic infantile convulsion are Shinguol(CV8), Ch'onchj'u(S25), T'aech'ung(Liv3), Kwanwon(CV4), Ch'ukt'aek(L5). 5. The meridians used on chronic infantile convulsion are Conception Vessel(CV), Governor Vessel(GV), Stomach Meridian(ST). 6. The meridian points used on accompanied symptoms with chronic infantile convulsion are Ch'onchj'u(S25), Kolli(CV11) on diarrhea, Taenung(P7), Shinmun(H7) on fainting spell, Kansu(B18), T'aech'ung(Liv3) on spasm. 7. The meridian Points and meridians are Paek'oe(GV14), Sangsung(GV23), Sugu(GV26) of Governor Vessel(GV) and Choiyung(CV16), Shinguol(CV16) of Conception Vessel(CV) and Taedon(Liv1), Changmun(Liv13).

• Applied Biological Chemistry
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• v.36 no.4
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• pp.315-317
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• 1993

To understand the molecular structure and pathogenesis mechanism of Korean garlic viruses (GV), virus particles were isolated from field-grown garlic leaves and RNA genome was isolated from them. It was used for constructing cDNA library for GV. Several cDNA clones for GV were isolated and classified into 4 different groups on the basis of cross Southern hybridization. Northern blot analysis of GV RNA with one of these cDNA clones shows that the clone is a cDNA for GV RNA.

• Journal of Veterinary Clinics
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• v.20 no.2
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• pp.224-228
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• 2003

This study was performed to evaluate the effect of electroacupuncture at some acupoint combinations on the cardiovascular system, especially on blood pressure. Electroacupuncture at acupoint combinations of CV2O(+)/GV-16(-),4(+)/GV16(-), KI1(+)/GV20(-), and HT9(+)/GV16(-) did not changed heart rates and blood pressure, but stimulation of HT1(+)/HT7(-) Increased systolic, diastolic and mean arterial blood pressure significantly in dogs anesthetized with tiletamine/zolazepam.

• Applied Microscopy
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• v.36 no.4
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• pp.279-289
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• 2006

This study has been carried out to understand the effect of SP3 and GV6 acupuncture on the hyperglycemic rat induced with Streptozotocin (STZ). Diabetes was induced in experimental groups by inraperitoneal injection of STZ (50mg/kg of body weight) twice by 24 h interval and the additional 100mg/kg 3 days after the earlier treatment. Control group was treated with tail-non acupoint, and experimental groups were treated SP3, GV6 and SP3+GV6 after hyperglycemic induction for 6 weeks. The body weight of control was lower than the experimental groups. The blood glucose was decreased significantly in the experimental groups. Glucose tolerance in acupuncture treated groups was improved. Blood cholesterol level and transaminase activites were lower in the experimental groups than in the control. In the SP3 or GV6 treated rats, hepatocyte degeneration were apparently decreased and the organelles were properly arranged. Furthermore, decrease in liver IGF-I mRNA expression was improved by the acupuncture in STZ-induced diabetic rats. In conclusion, our observation indicate that SP3 or GV6 acupoints treatment can exert beneficial effects in diabetes, with preservation of ${\beta}-cell$ function and liver function.