• 건설관리
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• 제23권1호
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• pp.6-10
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• 2022

• 대기
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• 제23권4호
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• pp.519-526
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• 2013

This study aims to analyze the vertical distribution of Asian dust measured by LIDARs at three weather stations in Baengnyeongdo (BND), Munsan (MS), and Gunsan (GS) during 10~11 May 2010, and thereby investigate their effectiveness. Asian dust passed through from central to south-western part of Korea. Although dust particles were detected over the surface in MS and GS, LIDAR data showed that the Asian dust with non-spherical particles was observed in all of the three regions. It seems that the naked-eye observation could not detect dust over the surface of BND due to the temperature inversion below a height of 0.45 km. During the Asian dust events, the duration time of dust presented 9.5 hr (BND), 19.5 hr (MS), and 24.5 hr (GS), respectively with the longest time in GS, whereas dust altitudes ranged from 0.4 to 1.3 km (BND), 0.1 to 2.8 km and 4.1 to 4.2 km (MS), and 0.2 to 2.0 km (GS), respectively, while showing the highest altitude in MS. Aerosol optical thickness (AOT) retrieved by LIDAR and skyradiometer (SR), located close to the LIDAR sites, was compared. MS (LIDAR) and Seoul (SR) attained the AOT of 0.64 and 0.50, and GS (LIDAR) and Gongju (SR) attained the AOT of 0.38 and 0.54, respectively. As SR-derived angstrom exponents (AE) during the time period determined as Asian dust by LIDAR data were 0.17 in Seoul (near MS) and 0.30 in Gongju (near GS), it can be said that the characteristics of dust particles were appeared. During the study period, depolarization ratio could serve as a useful indicator to determine dust aerosol. But, it still seems essential to conduct further investigation with longer period of data to better describe the discrepancy of AOT between LIDARs and SR.

• Journal of Microbiology and Biotechnology
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• 제21권1호
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• pp.93-99
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• 2011

Amongst a number of potential nonviral vectors, cationic liposomes have been actively researched, with both gemini surfactants and bola amphiphiles reported as being in possession of good structures in terms of cell viability and in vitro transfection. In this study, a cholesterol-based diquaternary ammonium gemini surfactant (Chol-GS) was synthesized and assessed as a novel nonviral gene vector. Chol-GS was synthesized from cholesterol by way of four reaction steps. The optimal efficiency was found to be at a weight ratio of 1:4 of lipid:DOPE (1,2-dioleoyl-L-${\alpha}$- glycero-3-phosphatidylethanolamine), and at a ratio of between 10:1~15:1 of liposome:DNA. The transfection efficiency was compared with commercial liposomes and with Lipofectamine, 1,2-dimyristyloxypropyl-3-dimethylhydroxyethylammonium bromide (DMRIE-C), and N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTAP). The results indicate that the efficiency of Chol-GS is greater than that of all the tested commercial liposomes in COS7 and Huh7 cells, and higher than DOTAP and Lipofectamine in A549 cells. Confirmation of these findings was observed through the use of green fluorescent protein expression. Chol-GS exhibited a moderate level of cytotoxicity, at optimum concentrations for efficient transfection, indicating cell viability. Hence, the newly synthesized Chol-GS liposome has the potential of being an excellent nonviral vector for gene delivery.

• BMB Reports
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• 제36권3호
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• pp.326-331
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• 2003

The fission yeast cells that contained the cloned glutathione synthetase (GS) gene showed 1.4-fold higher glutathione (GSB) content and 1.9-fold higher GS activity than the cells without the cloned GS gene. Interestingly, $\gamma$-glutamylcysteine synthetase activity increased 2.1-fold in the S. pombe cells that contained the cloned GS gene. The S. pombe cells that harbored the multi copy-number plasmid pRGS49 (containing the cloned GS gene) showed a higher level of survival on solid media with cadmium chloride (1 mM) or mercuric chloride ($10\;{\mu}M$) than the cells that harbored the YEp357R vector. The 506 bp upstream sequence from the translational initiation point and N-terminal8 amino acid-coding region were fused into the promoteriess $\beta$-galactosidase gene of the shuttle vector YEp367R to generate the fusion plasmid pUGS39. Synthesis of $\beta$-galactosidase from the fusion plasmid pUGS39 was significantly enhanced by cadmium chloride and NO-generating S-nitroso-N-acetylpenicillamine (SNAP) and sodium nitroprusside (SN). It was also induced by L-buthionine-(S,R)-sulfoximine, a specific inhibitor of $\gamma$-glutamylcysteine synthetase (GCS). We also found that the expression of the S. pombe GS gene is regulated by the Atf1-Spc1-Wis1 signal pathway.

• JSTS:Journal of Semiconductor Technology and Science
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• 제11권2호
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• pp.95-103
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• 2011

This paper proposes a 6b 1.2 GS/s 47.8 mW 0.17 $mm^2$ 65 nm CMOS ADC for high-rate wireless personal area network systems. The proposed ADC employs a source follower-free flash architecture with a wide input range of 1.0 $V_{p-p}$ at a 1.2 V supply voltage to minimize power consumption and high comparator offset effects in a nanometer CMOS technology. The track-and-hold circuits without source followers, the differential difference amplifiers with active loads in pre-amps, and the output averaging layout scheme properly handle a wide-range input signal with low distortion. The interpolation scheme halves the required number of pre-amps while three-stage cascaded latches implement a skew-free GS/s operation. The two-step bubble correction logic removes a maximum of three consecutive bubble code errors. The prototype ADC in a 65 nm CMOS demonstrates a measured DNL and INL within 0.77 LSB and 0.98 LSB, respectively. The ADC shows a maximum SNDR of 33.2 dB and a maximum SFDR of 44.7 dB at 1.2 GS/s. The ADC with an active die area of 0.17 $mm^2$ consumes 47.8 mW at 1.2 V and 1.2 GS/s.

• 한국식생활문화학회지
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• 제9권2호
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• pp.125-130
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• 1994

본 연구는 새우젓(5%, 10%) 및 찹쌀풀(2.5%)의 첨가가 김치발효중 저급 질소화합물들의 함량변화에 미치는 영향을 살펴 본 것이다. 김치를 $10^{\circ}C$에서 14일간 저장하면서 pH와 총산도, 유리당을 측정하여 김치의 발효정도를 조사하고, nitrite, dimethylamine(DMA)과 Volatile Basic Nitrogen(VBN) 함량을 정량하였다. 김치 발효초기의 아질산염 함량은 0.16-0.31 mg/kg의 수준을 보였으며, 그 중에서도 10% 새우젓 첨가시료들 $(S_2,\;GS_2)$이 비교적 높은 것으로 나타났다. 그러나 적숙기인 숙성 6일 이후에는 모든 시료들이 검출한계미만으로 흔적정도를 나타냈다. 발효가 진행되면서 시료중의 DMA 함량은 점차적으로 증가하였으며, 젓갈첨가량이 높을 수록 많이 검출되었다. 새우젓+찹쌀죽 첨가구$(GS_1,\;GS_2)$는 새우젓만 첨가한 시료들$(S_1,\;S_2)$보다 더 많이 검출되었다. 새우젓을 첨가한 시료들의 DMA 함량은 발효초기에 0.03-1.2 mg/kg이었으며, 발효말기에는 1.6-2.26 mg/kg이었다. VBN 함량은 발효가 진행되면서 점점 증가하여 새우젓 첨가구들$(S_1,\;S_2)$ 또는 새우젓과 찹쌀풀을 첨가한 시료들$(GS_1,\;GS_2)$이 새우젓을 첨가하지 않은 시료들(C, G)보다 분명하게 높았으며, 새우젓 첨가구와 새우젓+찹쌀풀 첨가구는 유사한 양상을 보였으므로, 찹쌀풀을 첨가하는 것이 VBN 함량에 영향을 주지 않는 것으로 보인다.

• 한국환경농학회지
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• 제34권3호
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• pp.192-195
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• 2015

BACKGROUND: The growing season (GS) has been understood as a useful indicator for climate change due to high relationship with increasing temperature. Hear this study was conducted to examine changes in the thermal GS over South Korea from 1970 to 2013 based on daily mean air temperature for assessing the temporal and spatial variability in GS. METHODS AND RESULTS: Three GS parameters (starting date, ending date, and length) were determined at 19 stations throughout South Korea. The results show that the GS has been extended by 4.2 days/decade between 1970 and 2013 on average. The growing season start (GSS) has been advanced by 2.7 days/decade and the growing season end (GSE) has been delayed by 1.4 day/decade. Spatial variation in the GS parameters in Korea are shown. The GS parameters, especially GSS, of southeastern part of Korea have been changed more than that of northwestern part of Korea. The extension of GS may be more influenced on earlier onset in spring rather than later GSE. CONCLUSION: Under climate change scenarios, the GS will be more extended due to delayed GSE as well as advanced GSS. And These are more notable in the northeastern part of Korea.

• 한국식품과학회지
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• 제30권6호
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• pp.1404-1408
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• 1998

울금과 자초, 자초와 고삼, 고삼과 감초, 감초와 오미자 추출물 혼합액 1% 첨가가 배추김치의 보존성 향상에 미치는 영향을 $10^{\circ}C$에서 25일간 숙성시키면서 조사하였다. 김치의 pH와 산도는 숙성이 진행됨에 따라 급격히 감소, 증가하는 경향을 나타내었는데, 한약재 추출물을 혼합 첨가한 김치는 대조구에 비해 이의 속도가 매우 완만하게 나타났다. 특히 SG, GS 첨가구의 pH 감소속도와 산도 증가속도는 매우 느려 pH는 숙성 20일경 각각 4.19, 4.16을 나타내었고, 산도는 0.62, 0.64%를 나타내었다. 미생물 변화는 한약재 추출물 혼합 첨가구가 대조구에 비해 균 성장을 크게 억제시켰으며, 특히 GS, SG 첨가 김치는 적숙기인 숙성 15일째 대조구에 비해 총균수는 각각 1.3, 1.32 $log_{10}$ cycle, 유산균수는 1.24, 1.14 $log_{10}$ cycle 정도 억제되었다. 김치의 신맛은 김치 적숙기인 $10{\sim}15$일경 대조구에 비해 한약재 추출물 첨가구에서 약하게 나타났으며, 종합적인 맛은 한약재 고유의 향과 맛으로 인해 전반적으로 나쁘게 나타나 이를 보완하기 위한 연구가 수행되어야 할 것으로 보여진다.

• 폴리머
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• 제39권1호
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• pp.88-98
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• 2015

폴리이미드(PI) 나노복합체 필름 제조에 사용된 작용기화 4-amino-N-hexadecylbenzamide graphene sheets (AHB-GSs)는 graphene oxide 분산액에 4-amino-N-hexadecylbenzamide(AHB)를 반응시켜 합성하였다. AHB-GS의 주사탐침 현미경(atomic force microscope, AFM) 이미지와 모식도를 통해서 AHB-GS의 평균 두께가 약 3.21 nm임을 확인하였다. PI는 4,4'-biphthalic anhydride와 bis(4-aminophenyl)sulfide를 사용하여 합성하였다. PI 나노복합체는 0-10 wt%의 다양한 함량의 AHB-GS를 용액 삽입(solution intercalation) 방법을 사용하여 합성하였고, 이미드화는 각각 $250^{\circ}C$ 및 $350^{\circ}C$까지 열 처리하였다. AHB-GS는 대부분 고분자 매트릭스에 잘 분산되었고 약간 뭉친 것도 있었지만 마이크로미터 수준의 입자는 관찰되지 않았다. TEM으로 관찰하였을 때, 평균적으로 입자의 두께는 10 nm 미만이었다. PI 복합체 필름 중 소량의 AHB-GS만으로도 가스 투과도와 전기 전도도는 향상되었지만, 반대로 유리전이 온도와 초기 분해 온도는 AHB-GS의 함량이 10 wt%까지 증가함에 따라 지속적으로 감소되는 경향을 보였다. 전체적으로는, $250^{\circ}C$까지 이미드화한 PI에 비해 $350^{\circ}C$까지 열처리한 PI 필름이 보다 향상된 특성을 보였다.

• 대한한방소아과학회지
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• 제34권1호
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• pp.37-47
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• 2020

Objectives After inducing dermatitis in 6-week-old mice, we tried to find out the effects of recovery in the damaged skin by administering genistein and palmitoylethanolamide (PEA) Methods The 6-week-old mice were divided into the control group (Ctrl), dermatitis causing group (AcDE), genistein-administered group after the onset of dermatitis (GsT), and PEA-administered group after the onset of dermatitis (PEAT). Seven mice were assigned to each group. Changes in the skin barrier were observed after three days of administration following the onset of dermatitis. Results In the GsT and PEAT, there was less skin damage compared to the AcDE, and the lowest skin damage showed in the GsT. The intensity of CB1 and CB2 expression was increased by 64% (CB1) and 39% (CB2) in the GsT, and 38% (CB1) and 28% (CB2) in the PEAT compared to the AcDE. The E-catherin positive reaction was decreased in the AcDE, while the E-catherin positive reaction was increased in the GsT (76%) and PEAT (34%). The p-JNK positive reaction was increased in the AcDE, while the p-JNK positive reaction was decreased in the GsT (60%) and PEAT (39%). Toxic Hepatopathy was not observed in the liver tissue of Genistein administered 3OGsT, and PEA administered 3OPEAT. Conclusions Genistein has recovery effect on dermatitis damage through active induction of the endocannabin system (ECS).