• Title/Summary/Keyword: GPF

검색결과 20건 처리시간 0.029초

Gastropleural Fistula: A Rare Complication of Ewing Sarcoma

  • Bozkurt, Mehmet Abdussamet;Kones, Osman;Basoglu, Irfan;Alis, Halil
    • Journal of Chest Surgery
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    • 제46권4호
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    • pp.293-294
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    • 2013
  • Gastropleural fistula (GPF) is a rare condition that can occur as a consequence of prior pulmonary surgery, trauma, or malignancy. Conservative management usually fails, and gastrectomy and even thoracotomy is often required, especially in debilitated patients. We present a patient with GPF who had a history of Ewing's sarcoma. Diagnosis of GPF was confirmed by upper gastrointestinal system endoscopy and radiographic contrast examination, and the patient underwent a laparoscopic wedge resection of the fistula. To our knowledge, this is the first report of a GPF, in the formation of which recurrence of Ewing's sarcoma had played a role and in the treatment of which wedge resection of the fistula was performed. Laparoscopic treatment of GPF may be associated with less morbidity and should be considered as the initial procedure of choice.

대학원생들의 연구관련 성과 변인들의 차이 분석: 글로벌 박사양성 프로젝트와 두뇌한국21사업을 중심으로 (An Analysis of the Differences in Research-related Constructs: Serial Comparson of the Graduate Students in Global Ph. D Fellowship and Brain Korea 21 Projects)

  • 장덕호
    • 공학교육연구
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    • 제16권3호
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    • pp.20-27
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    • 2013
  • The purpose of this study is to compare the key research-related constructs, research insterest, research self-efficacy, research productivity, and research outcome expectation of the graduate students, who are participating in Global Ph.D Fellowship (GPF) and Brain Korea (BK) 21 projects. The overall results show that the mean scores of GPF students in research interest, research self-efficacy, research productivity, and research outcome expectation are higher than those of BK21. However, the higher mean scores of doctoral students in both GPF and BK21 projects imply that the longer you stay in graduate program, the better researcher you can be. Although GPF program selected higher potential students and they seem to work very hard with high expectation to be competent researchers, compatible outcome also could be possible by BK21 project.

A novel protocol for batch-separating gintonin-enriched, polysaccharide-enriched, and crude ginsenoside-containing fractions from Panax ginseng

  • Rami Lee;Han-Sung Cho;Ji-Hun Kim;Hee-Jung Cho;Sun-Hye Choi;Sung-Hee Hwang;Hyewon Rhim;Ik-Hyun Cho;Man-Hee Rhee;Do-Geun Kim;Hyoung-Chun Kim;Seung-Yeol Nah
    • Journal of Ginseng Research
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    • 제47권3호
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    • pp.366-375
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    • 2023
  • Background: Ginseng contains three active components: ginsenosides, gintonin, and polysaccharides. After the separation of 1 of the 3 ingredient fractions, other fractions are usually discarded as waste. In this study, we developed a simple and effective method, called the ginpolin protocol, to separate gintonin-enriched fraction (GEF), ginseng polysaccharide fraction (GPF), and crude ginseng saponin fraction (cGSF). Methods: Dried ginseng (1 kg) was extracted using 70% ethanol (EtOH). The extract was water fractionated to obtain a water-insoluble precipitate (GEF). The upper layer after GEF separation was precipitated with 80% EtOH for GPF preparation, and the remaining upper layer was vacuum dried to obtain cGSF. Results: The yields of GEF, GPF, and cGSF were 14.8, 54.2, and 185.3 g, respectively, from 333 g EtOH extract. We quantified the active ingredients of 3 fractions: L-arginine, galacturonic acid, ginsenosides, glucuronic acid, lysophosphatidic acid (LPA), phosphatidic acid (PA), and polyphenols. The order of the LPA, PA, and polyphenol content was GEF > cGSF > GPF. The order of L-arginine and galacturonic acid was GPF >> GEF = cGSF. Interestingly, GEF contained a high amount of ginsenoside Rb1, whereas cGSF contained more ginsenoside Rg1. GEF and cGSF, but not GPF, induced intracellular [Ca2+]i transient with antiplatelet activity. The order of antioxidant activity was GPF > GEF = cGSF. Immunological activities (related to nitric oxide production, phagocytosis, and IL-6 and TNF-α release) were, in order, GPF > GEF = cGSF. The neuroprotective ability (against reactive oxygen species) order was GEF > cGSP > GPF. Conclusion: We developed a novel ginpolin protocol to isolate 3 fractions in batches and determined that each fraction has distinct biological effects.

조속기 응동 조류계산 기반 장기 전압안정도 모의 (Governor-Response Power Flow Based Long-term Voltage Stability Simulation)

  • 송화창;김영곤;이병준
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2008년도 추계학술대회 논문집 전력기술부문
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    • pp.160-162
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    • 2008
  • This paper present a practical method for long-term voltage stability simulation based on a governor-response power flow. Governor-response power flow (GPF) is to model the long-term system response in the interval from 3 to 30 seconds after disturbance. In this paper, it is assumed that the GPF model ran capture the system state before load restoration starts in contingent conditions. This paper discusses the applicability of GPF to long-term simulation for voltage stability analysis and then explains the GPF formulation and the procedure of the proposed simulation. In addition the paper includes the simulation results with the modified New England 39-bus system.

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Effects of Radioprotectors on DNA Repair Capacity of Tumor Cells

  • Kim, Choon-Mi;Kim, Mi-Kyung
    • Archives of Pharmacal Research
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    • 제16권4호
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    • pp.259-264
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    • 1993
  • Three cell lines, CHO, L929 and B16 which are non-tumorigenic and cancer cells, respectively, were first tested for their survival in the presence of radioprotective ginseng protein fraction(GPF0. The influence of three radioprotectors-CPF, cysteamine, and 1-Methyl-2-bis[(2-methylthio)vinyl] quinolinium iodide (MVQI) on DNA repair capacity of UV damaged cells survival test, the GPF showed higher cytotoxicity in L929 and B16 than in CHO cells. However, the degree of cell killing was also investigated by measuring $^3H$-thymidine incorporation of PUVA treated cells. In cell survival test, the GPF showed higher cytotoxicity in L929 and B16 than in CHO cells. However, the degree of cell killing was not high enough to consider it as an antitumorigenic agent. Variable results were obtained in the effects on DNA repair capacity depending on the protectors and cell lines used. In pretreatment, the presence of GPF and MVOI brought about a sinificant increase in the capacity in both CHO and B16 cells. However, in L929, the enhancing effect was not shown. In all three cell lines, cysteamine showed lower repair capacity than control, suggesting the primary damage reduction in stronger enhancing effects in L929 and B16 cells, while it was weaker in CHO cells. Here also cystemine hsowed a very little or no increase in the capacity in all three cell lines. These results demonstrate that GPF has mild cytotoxicity in tumorignic cells and that GPF and MVQI enhance DNA repair capacity of UV damaged cells, whether they are tumorigenic or not. On the other hand, cysteamine shows only damage reduction effect. Celles of different genetic origin seem to give different responses to the modifier and different modifiers may possibly work by different mechanisms.

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다중 사용자 OFDMA 시스템에서의 사용자간 전송효율 최적화를 위한 Aggressive Subchannel Allocation 알고리즘 (Aggressive Subchannel Allocation Algorithm for Optimize Transmission Efficiency Among Users in Multiuser OFDMA System)

  • 고상준;허주;장경희
    • 한국통신학회논문지
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    • 제31권6A호
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    • pp.617-626
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    • 2006
  • 본 논문에서는 OFDMA 시스템 하향 링크에서 섹터 Throughput을 향상시키기 위하여, 모든 사용자의 채널 상태를 고려하여 동적 채널 할당을 진행하는 ASA(Aggressive Subchannel Allocation) 알고리즘을 제안한다. 그리고 제안한 알고리즘을 섹터 별 Frequency Reuse Factor 가 1인 2-tier 환경 하에서 Round Robin, ACG(Amplitude Craving Greedy), RCG(Rate Craving Greedy) 그리고 GPF(General Proportional Fair) 알고리즘과 함께 모의실험을 통하여 각 알고리즘의 성능을 분석한다. 그 결과 본 논문에서 제안한 ASA 알고리즘이 Round Robin 보다는 58 %, ACG 보다는 190 %, RCG 보다는 130 % 그리고 GPF보다는 8.5 % 높은 Sector Throughput을 보인다.

6'-O-Galloylpaeoniflorin Protects Human Keratinocytes Against Oxidative Stress-Induced Cell Damage

  • Yao, Cheng Wen;Piao, Mei Jing;Kim, Ki Cheon;Zheng, Jian;Cha, Ji Won;Hyun, Jin Won
    • Biomolecules & Therapeutics
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    • 제21권5호
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    • pp.349-357
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    • 2013
  • 6'-O-galloylpaeoniflorin (GPF) is a galloylated derivate of paeoniflorin and a key chemical constituent of the peony root, a perennial flowering plant that is widely used as an herbal medicine in East Asia. This study is the first investigation of the cytoprotective effects of GPF against hydrogen peroxide ($H_2O_2$)-induced cell injury and death in human HaCaT keratinocytes. GPF demonstrated a significant scavenging capacity against the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical, $H_2O_2$-generated intracellular reactive oxygen species (ROS), the superoxide anion radical ($O_2^-$), and the hydroxyl radical (${\cdot}$OH). GPF also safeguarded HaCaT keratinocytes against $H_2O_2$-provoked apoptotic cell death and attenuated oxidative macromolecular damage to DNA, lipids, and proteins. The compound exerted its cytoprotective actions in keratinocytes at least in part by decreasing the number of DNA strand breaks, the levels of 8-isoprostane (a stable end-product of lipid peroxidation), and the formation of carbonylated protein species. Taken together, these results indicate that GPF may be developed as a cytoprotector against ROS-mediated oxidative stress.

비선형 내점법을 이용한 최적 조속기 응동 조류계산 (Optimal Governor Response Power Flow with Nonlinear Interior Point Method)

  • 김태균;이병준;송화창;차준민
    • 전기학회논문지
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    • 제56권9호
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    • pp.1527-1534
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    • 2007
  • This paper proposes a new concept of optimal governor-response power flow (OGPF) to obtain an optimal set of control parameters when the systems are in mid-term conditions after disturbances, ignoring the system dynamics. The idea of GOPF simply comes from the attempt to find an optimal solution of the governor-response power flow (GPF), which is a pre-exiting tool that is used to get power flow solutions that would exist several seconds after an event is applied. GPF incorporates the simplified model of governors in the systems into the power flow equations. This paper explains the concept of OGPF and depicts the OGPF formulation and application of a nonlinear interior point method as the solution technique. Also, this paper includes an example with New England 39-bus test system to illustrate the effectiveness of GOPF.

위치기반 Ad hoc 라우팅에서 경로복구 방법론 (A Route Recovery Method for position based Ad hoc routing)

  • 차우석;유석대;조기환
    • 한국정보과학회:학술대회논문집
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    • 한국정보과학회 2002년도 봄 학술발표논문집 Vol.29 No.1 (A)
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    • pp.328-330
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    • 2002
  • Ad hoc 네트워크는 유선기반구조 없이 지리적으로 분산된 노드들이 동적으로 연결되어 자치적인 네트워크를 구성한다. 라우팅 프로토콜은 무선자원을 효율적으로 사용하기 위해서 최소의 오버 헤드를 갖도록 수행되어야 한다. 위치기반 라우팅 프로토콜은 위치정보를 이용하여 노드들간의 경로를 설정하고 유지할 필요 없이 직접 데이터 패킷을 전송하도록 지원하는 라우팅 프로토콜이다. 본 논문에서는 위치기반 라우팅 프로토콜인 GPF(Greedy Packet Forwarding)기법을 이용하여 패킷을 전송하는 도중 패킷을 전송할 수 없는 영역에 도착했을 때, 지역적인 flooding을 이용하여 이를 복구하는 방법론을 제시한다. 이 복구방법에서 전반적인 패킷 전송은 GPF기법을 적용하며, GPF기법을 적용할 수 없는 영역에서만 지역적으로 flooding 알고리즘을 적용한다. 따라서 제어메시지를 지역에 국한시켜 사용함으로써 제한된 무선자원을 효율적으로 사용할 수 있다. 또한 노드들의 수가 증가하는 네트워크 환경에서 보다나은 확장성을 기대할 수 있다.

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