• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.1
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• pp.21-26
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• 1996

본 연구는 streptozotocin 유발 당뇨쥐에서의 MFO계활성 변화 및 이에 지질과산화를 관찰하고자 체중이 140kg 내외의 Sprague-Dawley 종 흰쥐 숫컷을 대조군과 당뇨 유발 시험군으로 나누어 4주간 사육하였다. 당뇨군은 STZ로 당뇨를 유발시켰으며 당뇨 유발 6일후 쥐를 희생기켜 간조직 및 폐조직 microsome 중의 cytochrome $P_{450}$ 및 cytochrome $b_[5}$ 함량과 NADPH-cytochrome $P_{450}$ reductase 활성도를 측정하고 아울러 microsome내의 지질과산화물을 측정하여 다음과 같은 결과를 얻었다. 실험군간에 식이 섭취량은 차이가 없었으나, 체중 증가량과 식이 효율은 당뇨군이 STZ군에 비해 현저하게 감소하였다. 간장 및 폐조직의 무게는 대조군과 당뇨군간에 유의적인 차이는 없었다. 간조직 및 GP조직 중의 cytochrome $P_{450}$ 함량은 대조군에 비해 당뇨군이 150%, 175%씩 증가하였다. 간조직 및 폐조직 중의 cytochrome $b_{5}$은 대조군에 비해 당뇨군이 53%,116%씩 각각 증가하였다. 간조직에서의 NADPH-cytochrome $P_{450}$ reductase 활성은 당뇨군이 대조군에 비해 46% 증가하였으며, 폐조직에서는 75%증가하였다. 지질과산화물가는 당뇨군이 대조군에 비해 간족에서는 약 95% 높았으며 폐조직에서는 73%높았다. 이상의 결과에서 STZ 유발 당뇨쥐에서는 MFO system의 활성도가 대조군에 비해 현저하게 증가되고 지질과산화반응이 같으 srudgid이 촉진되었으며 폐조직에서도 간조직에서와 비슷한 경향이었다. 이러한 것은 당뇨군에서는 MFO system의 활성증가로 free radical 생성이 증가되고 그 결과 지질과산화가 촉진되었다고 볼 수 있다.

• Journal of KIISE:Computer Systems and Theory
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• v.34 no.5_6
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• pp.249-256
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• 2007

GPS(generalized processor sharing) is a fair scheduling scheme that guarantees fair distribution of resources in an instantaneous manner, while virtual clock pursues fairness in the sense of long-term. In this paper, we notice that the degree of memorylessness is the key difference of the two schemes, and propose a unified scheduling model that covers the whole spectrum of history-sensitiveness. In this model, each application's resource right is represented in a value called deposit, which is accumulated at a predefined rate and is consumed for services. The unused deposit, representing non-usage history, gives the application more opportunity to be scheduled, hence relatively enhancing its response time. Decay of the deposit means partial erase of the history and, by adjusting the decaying rate, the degree of history-sensitiveness is controlled. In the spectrum, the memoryless end corresponds GPS and the other end with full history corresponds virtual clock. And there exists a tradeoff between average delay and long-term fairness. We examine the properties of the model by analysis and simulation.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1083-1088
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• 2016

Background: Cervical cancer is the second commonest cancer among Indian women and its association with human papilloma virus (HPV) is well established. This preventable cancer accounts for the maximum number of cancer related deaths among rural Indian women. Unlike in developed countries there are no organized cervical cancer screening programmes in India due to lack of resources and manpower. Objective: To detect genital HPV infection using urine samples among asymptomatic rural women in the age group of 18-65 years. Materials and Methods: The study area chosen was Perdoor village in Udupi Taluk, Karnataka State and all the women in the age group of 18-65 years formed the study cohort. A cross sectional study was conducted by house visits and 1,305 women were enrolled in the study. After taking written informed consent a data sheet was filled and early stream random urine samples were collected, transported to a laboratory at 4OC and aliquoted. Samples were tested using nested HPV PCR with PGMY09/11 and GP5+/6+ primers. Positive cases were genotyped by sequence analysis. Results: Study participants included 1,134 sexually active and 171 unmarried women with a mean age at marriage of 22.1 (SD=3.9) years. Study area showed high female literacy rate of 86.6%. Five urine samples tested positive for HPV DNA (0.4%). Conclusions: We found very low genital HPV infection rate among women from monogamous community. This is the first major population based study carried out among asymptomatic rural women to detect genital HPV infectio from Karnataka using urine samples.

• Journal of the Korean Association of Geographic Information Studies
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• v.5 no.4
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• pp.75-85
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• 2002

The introduction of GPS technique in transportation study make real time tracking of driving vehicle's position possible. Position information data gauged with three dimension(X, Y, Z) can be achieved with time-continuity and from more than two driving vehicles. For this field of study, in past day, there were many difficulties in collecting real time data, but now, it becomes easy thanks to this. But for the resonable result analysis, fully understanding of GPS data-accuracy must be proceeded. Because accompanied magnitude of error depends on the study's accuracy. For this reason, this study surveyed the GPS data's error and suggest calibrate technique. This study's result will be helpful for following studies using DGPS data. For this, this study takes two types study in road, and set triangulation coordinates, and compare it with GPS data. DGPS data contains less than 0.6m's error.

• Journal of Nutrition and Health
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• v.36 no.5
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• pp.425-436
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• 2003

The present study was conducted to evaluate the usefulness of common Korean legumes as a high-fiber supplement in therapeutic diets for diabetic patients. Streptozotocin-induced diabetic rats were used as animal models and four kinds of legumes, black soybean (BS), yellow soybean (YS), green pea (GP) and soybean curd residue (SCR) were tested as high-fiber supplements. Seven groups of normal and streptozotocin-induced diabetic rats were fed isocaloric experimental diets containing 8％ dietary fiber from one of four legumes or purified cellulose and pectin for 6 weeks. The effects of the legumes on the glucose and lipid metabolism of diabetic rats was examined and compared with the effects of cellulose and pectin. The legume supplementation did not show any beneficial effect on glucose tolerance, however, it exhibited a plasma cholesterol-lowering effect in diabetic rats. The cholesterol-lowering action was especially strong in BS and the degree of the effect was comparable to that of pectin. The levels of total lipids, cholesterol, and triglyceride in the hepatic tissues of rats fed legume diets were similar to those of the pectin group. All legume supplements induced an increase in fecal steroid excretion. The fecal cholesterol contents were significantly high following the supplementations of YS and SCR (p < 0.05). The excretion of fecal bile acids in the BS and YS groups was significantly higher than it was in the pectin group (p < 0.05). Concentration of lipid peroxidation products in the blood and urine of diabetic animals was lower in the legume groups than in the cellulose group. The levels of hepatic lipid peroxidation products were significantly lower in the BS and YS groups than in the pectin group (p < 0.05). From the results of this study, the plasma cholesterol-lowering effect of BS is possibly due to the significant (p < 0.05) in-crease in fecal steroid excretion, which suggests that BS could be beneficial in improving abnormal lipid metabolism in diabetic rats. (Korean J Nutrition 36(5): 425∼436, 2003)

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3907-3912
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• 2015

Purpose: To investigate the antitumor activity and mechanism of chloroquine (CQ) in combination with cisplatin (DDP) in nude mice xenografted with gastric cancer SGC7901 cells. Materials and Methods: 35 cases of gastric cancer patients with malignant ascites were enrolled and intraperitoneal cisplatin injection was performed. Ascites were collected before and 5 days after perfusion for assessment of autophagy levels in cancer cells. In addition, 24 tumor-bearing mice were randomly divided into control, DDP, CQ and CQ + DDP groups. Results: In 54.3% (19/35) of patients the treatment was therapeutically effective (OR), 5 days after peritoneal chemotherapy, 13 patients had the decreased ascites Beclin-1 mRNA levels. In 16 patients who had NR, only 2 cases had decreased Beclin-1 (P=0.001). Compared with the control group, the xenograft growth in nude mice in the DDP group was low, and the inhibition rate was 47.6%. In combination with chloroquine, the inhibition rate increased to 84.7% (P<0.01). The LC3-II/I ratio, and Beclin1 and MDR1/P-gp expression were decreased, while caspase 3 protein levels increased (P<0.05). Conclusions: Antitumor ability of cisplatin was associated with autophagy activity and chloroquine can enhance chemosensitivity to cisplatin in gastric cancer xenografts nude mice.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.7 no.2
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• pp.13-25
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• 2008

In this paper, we propose the Location Awareness System adjusting Ranging Technology for CSS(Chirp Spread Spectrum) which is adopted on 2.45GHz standard in IEEE 802.15.4a and TOA(Time-of-Arrival) algorithm. The conventional methods have adopted RSSI, ultrasonic waves and infrared rays in Zigbee. RSSI measures strength indication of received signal and recognizes the position of nodes in RF boundary. However, this technology has the following problems; lots of error by the change of the channel environment and much power consumption. In this paper, adopting chirp pulse on 2.45GHz standard in IEEE 802.15.4a and SDS-TWR(Symmetrical Double Side-Two Way Ranging) method using the characteristic of Spread Spectrum, a new Location Awareness System is suggested. The distance and the coordinate are measured within ${\pm}\;5cm$ by TOA(Time of Arrival) algorithm and proposed algorithm and the data in error rate is decreased less than 1%. Through these results, the algorithm suggested in this paper is verified for its performance in a computer simulation.

• Restorative Dentistry and Endodontics
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• v.16 no.1
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• pp.87-105
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• 1991

The purpose of this experiment was to measure the leaking and solubility of commonly used dental restorative materials - Silux plus (CS), Hi-pol (CH), Clearfil F-II, Fissureseal (FS), Glass-Ionomer cement Fuji Type II (GI), Amalgam Cavex 68 (AM), Zinc Phosphate Cement (ZP) and gutta-percha (GP) and investigate the relation between the solubility and marginal leakage. Disc-shape specimens were fabricated with each material and dipped into deionized water, 0.01M lactic acid and 0.005M KOH solution, thus the total ionic concentrations in each solution was measured with ion chromatograph after 1, 3, and 7 days, respectively. For the solubility test, each specimen was immersed in 0.001M and 0.01M lactic acid for 24 hours, respectively and total weight loss was calculated. Also, Zn leaking through the margin of restorations was measured. The obtained results were as follows: 1. The amounts of eluted ion from the eight materials were most in 0.01M lactic acid and least in deionized water. 2. Of the eight materials, the fluoride release was greatest for glass ionomer cement (GI) in 0.01 M lactic acid after 7 days. 3. In analysis of the divalent cation, Mg was eluted most for zinc phosphate cement (ZP) and Ca for Clearfil F-II (CF) in 0.01M lactic acid after 7 days. 4. In analysis of transition metals, Cu and Zn were detected only. 5. The solubility rate of eight materials was greater in 0.01M lactic acid than in 0.001M for 24 hours, for zinc phosphate cement (ZP) the rate was greatest (5.4%) in 0.001M lactic acid, and amalgam least (0.01%). 6. The Zn concentration of restorative material with Z.P.C base was greater in 0.01M lactic acid than in 0.001M lactic acid.

• Korean Journal of Agricultural Science
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• v.48 no.4
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• pp.843-853
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• 2021

The objectives of this paper were to simply estimate soil loss levels as caused by wind in reclaimed tidal flat land (RTFL) and the threshold wind velocity in the RTFL. For this experiment, RTFL located at Haenam Bay was selected and a total of 150 soil samples were collected at the Ap horizon from the five soil series. The particle distribution curves, including the limit of the non-erodible particle size (D > 0.84 mm) for each Ap horizon soil, show that the proportions of non-erodible particle sizes that exceeded 0.84 mm were 4.3% (Taehan, TH), 8.9% (Geangpo, GP), 0.5% (Bokchun, BC), 1.6% (Poseung, PS) and 1.4% (Junbook, JB), indicating that the amount of non-erodible soil particles increased with an increase in the sand content. The average monthly, daily and instantaneous wind velocities were higher than the threshold friction velocity (TFV) calculated according to the dynamic velocity (V_d) by Bagnold, while the average monthly wind velocity was lower than those of the TFV suggested by the revised wind erosion equation (RWEQ) and wind erosion prediction system (WEPS). The susceptible proportions of erodible soil particles from the Ap horizon soil samples from each soil series could be significantly influenced by the proportion of sand particles between 0.025 and 0.5 mm (or 0.84 mm) in diameter regardless of the threshold wind velocity. Thus, further investigations are needed to estimate more precisely soil erosion in RTFL, which shows various soil characteristics, as these estimations of soil loss in the five soil series were obtained only when considering wind velocities and soil textures.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.5C
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• pp.303-312
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• 2006

This study is to evaluate the mechanical characteristics of flowable backfill and offer a guide line of mixture proportion based on soil types for constructing underground power utilities. Flowable backfill is known as soil-cement slurry, void fill, and controlled low-strength material(CLSM). The benefits of CLSM are reduced equipment costs, faster construction, re-excavation in the future, and the ability to place materials in confined spaces, which are narrow parts or perimeters of underground power cables nearly impossible for compaction. The flowable slurry mixed with 17 soils and 6 accelerated mixtures in the laboratory were evaluated for flowability and unconfined compressive strength to meet the target values of this study.