• Title/Summary/Keyword: GMD

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The Study on the FRBR Adoption into Cataloging Rule Focused on its Expression Level (표현형 계층을 중심으로 한 FRBR 모형 분석 및 목록 체계 수용에 관한 연구)

  • Cho Jane
    • Journal of Korean Library and Information Science Society
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    • v.36 no.2
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    • pp.221-239
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    • 2005
  • FRBR, as is new conceptual model of bibliography based on entity-relation model, direct to revision of AACR 3.JSC has progressed work to adopt FRBR conceptual model into cataloging rule, especially for solving the problem of expression level, propose to overall change of uniform title & GMD. This study considers the matters about expression level of FRBR model. And examine possibility of adoption FRBR model to domestic cataloging rule and making out practice.

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Effects of Foreign Exchange Rates on Stock Returns

  • Chi, Ho-Joon;Kim, Young-Il
    • The Korean Journal of Financial Studies
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    • v.9 no.1
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    • pp.221-244
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    • 2003
  • This study is aimed to investigate the effects of foreign exchange rates on stock market returns. For the United States, the United Kingdom, Germany, Japan and Korea, the cross-correlation precedence of foreign exchange rate on stock market is found in the case of Germany and Korea. But that of stock market is not observed in any case. We performed three kinds of causality and exogeneity test of Granger test, Sims test and Geweke-Meese-Dent test. The analyses on the full period show the time-lag causal, exogeneous relation of foreign exchange rates with Granger, Sims and GMD test for Korea. The United Kingdom presents the significance with Granger and Sims test while Germany reveals the time-lag relation with Granger and GMD test. When we divide the period into two parts with the Louvre Accord, the first part give the less degree of time-lag relation. But in the second period the three kinds of causality and exogeneity test propose consistent time-lag relation with foreign exchange rates on stock markets for the United Kingdom and Korea with the three test methods. And Granger's test prove German foreign exchange market have a time-lag relation on stock market.

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Effects of Traditional Chinese Herbal Medicine Shengmai-San and Pyungwi-San on Gastrointestinal Motility in Mice (생맥산 및 평위산 추출물의 위장관 운동 조절 효능에 관한 연구)

  • Lee, Min Cheol;Park, Jin Ryeong;Shim, Ji Hwan;Ahn, Tae Seok;Kim, Byung Joo
    • Journal of Korean Medicine for Obesity Research
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    • v.15 no.2
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    • pp.68-74
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    • 2015
  • Objectives: The purpose of this study was to investigate the effects of Shengmai-san and Pyungwi-san, a herbal product used in traditional Chinese medicine, on gastrointestinal (GI) motility in mice. Methods: The in vivo effects of Shengmai-san and Pyungwi-san on GI motility were investigated by measuring the intestinal transit rates (ITRs) using Evans blue in normal mice and in mice with experimentally induced GI motility dysfunction (GMD). GMD was induced by injecting acetic acid or streptozotocin intraperitoneally. Results: In normal Institute of Cancer Research mice, ITRs were significantly and dose-dependently increased by Shengmaisan (0.01~1 g/kg) and Pyungwi-san (0.01~1 g/kg). The ITRs of acetic acid induced peritoneal irritation model and streptozotocin-induced diabetic model mice were significantly reduced compared to normal mice, and these reductions were significantly and dose-dependently inhibited by Shengmai-san (0.01~1 g/kg) and Pyungwi-san (0.01~1 g/kg). Conclusions: These results suggest that both Shengmai-san and Pyungwi-san are a good candidate for the development of a prokinetic agent that may prevent or alleviate GMD.

A Study on the Medium Designator In Non-book Materials (비도서자료의 매체표시에 관한 연구)

  • Nam Tae Woo
    • Journal of the Korean Society for Library and Information Science
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    • v.15
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    • pp.119-140
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    • 1988
  • This paper is the study on the Medium Designator in Non-book materials. Main contents of this study were as follows; 1. The medium designator serves to indicate the class of material to which an item belongs. This is used to give an 'early warning' ;to the catalogue user. 2. This medium designator may be further divided into two elements ; a general material designation (GMD), for example video-recording, and a specific material designation (SMD), for example, videodisc. 3. GMD: In cataloging, a term indicating the broad class of material to which a bibliographic item belongs, such as 'motion picture', and SMD : In descriptive cataloging, a term indicating the special class of material (usually the class of physical object) to which a biblographic item belongs, such as videocassette. 4. Locating the medium designator after the title proper was not prescribed until ISBD(G) and AACR2. In pre-ISBD(G) codes, the ,early, warning type of medium designator was placed after all title information. But in AACR2, the medium designator is placed after the title proper, but before parellel title and other title information. 5. In Terminology, Two separate lists of designations are given in AACR2, l.1C1, one for British and one for North American use. The British list contains fewer terms, and uses generic categories to group together some of the North American list. 6. The problem of where to place the medium designator might be circumvented by using some kind of early alerting device other than a formal element of biblliographic description. Various alternatives have been suggested. A more popular device is the provision of symbols or 'media code' which are part of the call number and indicate the porticular medium type. 'Colour-coding' the use of used by some libraries but is now longly discouraged. 7. According to Frost. The medium designatorhas been generally reeognized as serving three functions; 1) as a statement of the nature or basic format of the item cataloged and thus as a meant of informing the user as to the type of material at hand; 2) as a description of the physical charaetistics of medium and as a means of alerting the user to equipment needed to make use of the item. 3) as a device to distinguish different physical formats which share the same title. 8. AACR2 raises some problems which decision makers have neet had to face preriously It provides a GMD for every item in the collection including books and it makes the application of any or all GMD's optional.

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Efficacy and Safety of Geochangmanryeung-dan and Acupuncture on Patient with Spinal Stenosis Treated by Epidural Steroid Injection: a Study Protocol for a Randomized Controlled Pilot Trial (경막외신경차단술로 치료 중인 척추관 협착증 환자에서 거창만령단과 침의 효능 및 안전성 연구(예비임상연구))

  • Lee, Hyun-jong;Lee, Cho In;Lee, Saram;Kwak, Min-Ah;Kwak, Sang Gyu;Roh, Woon-seok;Jung, Jin-yong
    • Korean Journal of Acupuncture
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    • v.32 no.3
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    • pp.99-107
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    • 2015
  • Objectives : This study was designed to obtain basic data for a further large-scale trial as evaluating the efficacy and safety of Geochangmanryeung-dan(GMD) and acupuncture on patient with spinal stenosis treated by epidural steroid injection. Methods: The study is a randomized controlled pilot clinical trial, conducted over 8 weeks. Twenty participants will be recruited and randomly allocated to 2 groups: an experimental(GMD and acupuncture with epidural steroid injection) group and a control(only epidural steroid injection) group. The epidural steroid injection will be administered once per 2 weeks for 6 weeks(3 times in total). GMD will be administered as a dose of 5 pills, 3 times per day, for 6 weeks. Acupuncture will be performed 2 times per week for 6 weeks(12 times in total). The primary outcome will be measured by visual analogue scale and self-rated walking distance. The secondary outcome will be measured by PainVision, short-form McGill Pain Questionnaire, and Oswestry Disability Index. Both primary and secondary outcomes will be measured at baseline, 2, 4, 6, and 8 weeks. The last assessment(at 8 weeks) will be performed 2 weeks after treatment cessation. Conclusions : This clinical trial, as the pilot study for a future large-scale trial, will provide clinical information for evaluating the efficacy and safety of GMD and acupuncture treatment in combination with epidural steroid injection for the treatment of spinal stenosis.

Relationship between Water Stable Aggregate and Macroporosity in Upland Soils Calculated by Fragmentation Fractal Dimension (파쇄프랙탈차원을 이용한 밭토양 내수성입단과 대공극률의 관계 평가)

  • Han, Kyung-Hwa;Cho, Hyun-Jun;Lee, Hyup-Sung;Hur, Seung-Oh;Ha, Sang-Keun
    • Korean Journal of Soil Science and Fertilizer
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    • v.42 no.1
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    • pp.58-64
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    • 2009
  • The objectives of this study were to investigate the aggregate fragmentation in wet-sieving and to evaluate the relationship between the aggregate fragmentation fractal dimension and macro-porosity of upland soils, using three different textural types of soils including Gopyeng series (Fine, Typic Hapludalfs), Gyuam series (Fine silty over coarse silty, Fluvaquentic Eutrudepts), and Jungdong series (Coarse loamy, Typic Udifluvents) located in Gyeonggi province. Undisturbed soil samples with five replicates were seasonally sampled and used for measuring water stable aggregate, macropores, and physico-chemical properties of soils. The aggregate stability in wet-sieving was digitalized as three types of fragmentation fractal dimension ($D_f$), geometric mean diameter (GMD), and mean weight diameter (MWD). $D_f$ had higher correlation with GMD than with MWD. Seasonal aggregate stability showed the highest values in summer, and decreased in the order of spring and autumn. The macroporosity had higher in topsoil, in autumn, and in ridge, than in plow pan layer, in summer, and in row, respectively. The relationship between $D_f$ and macroporosity, especially more than 99 m, showed high correlation only in soils with $D_f$ less than 3.1, which means more aggregated soils compared to soils with $D_f$ more than 3.1. Besides, in the soils with the fractal dimension less than 3.1, the power function relation between saturated hydraulic conductivity and macroporosity more than 99 m had relatively high determinant coefficient, and vice versa. Therefore, it could be thought that fragmentation fractal dimension is available for confirming macroporosity induced from aggregation.

Comparison of Diesel Exhaust Particle Concentration between Large Above-Underground Parking Lots (수도권 일부 대형상가 지상주차장 및 지하주차장의 공기중 디젤엔진배출 입자상물질의 공기중 농도 비교)

  • Kim, Boowook;Song, Dong-Woo
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.23 no.4
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    • pp.323-332
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    • 2013
  • Objectives: This study was conducted in order to investigate the diesel exhaust particle(DEP) concentrations in the thirteen parking lots of large shopping complex. Methods: The real-time black carbon(BC) concentration was determined using an Aethalometer, and elemental/organic carbon concentration was determined according to the method of the National Institute for Occupational Safety and Health(NIOSH) 5040. The particle number concentration(NC), lung deposited surface area concentration(LDSA) and geometric mean diameter(GMD) were determined using a DiSCmini aerosol monitor. Results: The average concentration of BC, EC, OC, NC, LDSA and GMD were $19.1{\mu}g/m^3$, $12.6{\mu}g/m^3$, $51.5{\mu}g/m^3$, $94,000particles/cm^{-3}$, $298{\mu}m^2/cm^{-3}$ and 57 nm in all parking lots, respectively, approximately 3-fold higher than those found in the urban outdoor. The average concentration of BC were $21.3{\mu}g/m^3$ in underground parking lots, 3-fold higher than above parking lots. Conclusions: Therefore, the parking lots at the large shopping complex can be considered a potentially dangerous environment with a high concentration of DEP nanoparticles.

A new function of glucocorticoid receptor: regulation of mRNA stability

  • Park, Ok Hyun;Do, Eunjin;Kim, Yoon Ki
    • BMB Reports
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    • v.48 no.7
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    • pp.367-368
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    • 2015
  • It has long been thought that glucocorticoid receptor (GR) functions as a DNA-binding transcription factor in response to its ligand (a glucocorticoid) and thus regulates various cellular and physiological processes. It is also known that GR can bind not only to DNA but also to mRNA; this observation points to the possible role of GR in mRNA metabolism. Recent data revealed a molecular mechanism by which binding of GR to target mRNA elicits rapid mRNA degradation. GR binds to specific RNA sequences regardless of the presence of a ligand. In the presence of a ligand, however, the mRNA-associated GR can recruit PNRC2 and UPF1, both of which are specific factors involved in nonsense-mediated mRNA decay (NMD). PNRC2 then recruits the decapping complex, consequently promoting mRNA degradation. This mode of mRNA decay is termed "GR-mediated mRNA decay" (GMD). Further research demonstrated that GMD plays a critical role in chemotaxis of immune cells by targeting CCL2 mRNA. All these observations provide molecular insights into a previously unappreciated function of GR in posttranscriptional regulation of gene expression. [BMB Reports 2015; 48(7): 367-368]