• 천문학회보
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• 제33권2호
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• pp.47.1-47.1
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• 2008

• 한국지역지리학회지
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• 제18권2호
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• pp.217-231
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• 2012

지리는 동아시아 삼국의 상호이해를 증진하는데 필요하고 충분한 조건을 갖춘 도구 교과이지만, 중국의 지리교육에 대한 국내 연구는 매우 부진하다. 이에 중국의 지리교육과정 변천 과정과 최근의 교육과정인 '지리과정표준'의 구성체계와 그 특징을 살펴보았다. 연구 결과는 다음과 같다. 첫째, 중국의 지리교육과정은 정치적 이념과 사회적 변화의 영향을 크게 받았으며, 번창${\rightarrow}$위축${\rightarrow}$진흥${\rightarrow}$발전의 과정으로 발달하였다. 둘째, 최근의 지리과정표준은 종합성과 실용성을 추구하는 내용표준 중심의 개혁적인 교육과정으로, 학생 중심 그리고 지리적 지식과 기능의 유기적 연계를 추구하는 활동 중심으로의 변화가 가장 큰 특징이다. 셋째, 지리과정표준은 크게 서언, 과정목표, 내용표준, 실시건의의 4부분으로 구성되어 있다. 넷째, 초급중학교 지리교육과정에서는 지구와 지도, 세계지리, 중국지리, 향토지리 4영역의 기초적인 지리 지식과 기본적인 지리 기능을 강조한다. 다섯째, 고급중학교 지리교육과정은 3개의 필수과목과 7개의 선택과목으로 구성되어 있으며, 학생들의 장래 직업과 지역 실정을 고려한 지리교육을 강조하고 있다.

• 생명과학회지
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• 제28권4호
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• pp.496-507
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• 2018

톡소이드는 독성은 제거되고 항원성은 유지시킨 독소 단백질로써, 다양한 병원체의 감염 및 질병 예방을 위해 지속적으로 연구 되었다. 그러나, 톡소이드의 활성 감소 및 이와 함께 사용하는 어쥬번트의 부작용 등이 지속적으로 보고되면서, 면역성은 강화하고 어쥬번트의 사용은 줄일 수 있는 톡소이드 항원 전달 시스템이 필요하게 되었다. 따라서, 이러한 단점을 개선하고자 최근 새로운 백신과 약물 전달수송을 위해 다양한 분야에서 활용하고 있는 마이크로/나노 운반체를 톡소이드 항원에 도입하고 있다. 이와 같은 마이크로/나노 운반체는 미생물 자체를 이용하거나 미생물을 통해 생산해 낼 수도 있으며, 더 나아가 다양한 소재의 폴리머를 이용하여 제작할 수 있다. 본 총설에서는 톡소이드 항원 전달을 위한 마이크로/나노 운반체를 미생물 유래의 ghost cells (GCs), 그람 음성 세균이 분비하는 outer membrane vesicles (OMVs) 및 고분자 폴리머로 구성된 nanoparticles (NPs)으로 분류하였다. 마지막으로 각 운반체에 대한 톡소이드 항원의 전달 방식 및 이를 적용하였을 때 일어나는 면역반응에 대하여 서술하였으며, 이를 통해 향후 톡소이드의 효율 및 부작용이 개선되기를 기대한다.

• Journal of Trauma and Injury
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• 제19권1호
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• pp.54-58
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• 2006

Purpose: The committee on trauma of the american college of surgeons, in its manual resources for optimal care of the injured patients involved in falls from less than 20 feet need not be taken to trauma centers. Because triage criteria dictate less urgency for low-level falls, this classification scheme has demerits for early detection and treatment of serious problems in the emergency room. Methods: A prospective analysis was conducted of 182 patients treated for fall-related trauma from June 2003 to March 2004. Falls were classified as group A (<3 m), group B (${\geq}3m$, <6 m), and group C (${\geq}6m$). Collected data included the patient's age, gender, site and height of fall, surface fallen upon, body area of first impact, body regions of injuries, Glasgow Coma Scale (GCS), Revised Trauma Score (RTS), and Injury Severity Score (ISS). Results: The 182 patients were classified as group A (105) 57.7%, group B (61) 33.5%, and group C (16) 8.8%. There was a weak positive correlation between the height of fall and the patients' ISS in the three groups (p<0.001). There were significant differences in GCS (p=0.017), RTS (p=0.034), and ISS (p=0.007) between group A and B. In cases that the head was the initial impact area of the body, the GCS (p<0.001) and the RTS (p=0.002) were lower, but the ISS (p<0.001) was higher than it was for other type of injuries. Hard surfaces as an impact surface type, had an influence on the GCS (p<0.001) and the ISS (p=0.025). Conclusion: To simply categorize patients who fall over 6 meters as severely injured patients doesn't have much meaning, and though patients may have fallen less than 6 meters, they should be categorized by using the dynamics (impact surface type, initial body - impact area) of their fall.

• 천문학회보
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• 제40권2호
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• pp.50.1-50.1
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• 2015

The origin of globular cluster (GC) color bimodality, which is one of the salient phenomena observed in most large galaxies, has not yet been fully resolved. The phenomenon has conventionally been interpreted as a bimodal metallicity distribution based on an assumption of linear GC color-metallicity relations (CMRs). Recent studies however suggest that nonlinear GC CMRs can cause a bimodal color distribution even from a single-peaked metallicity spread. Using photometric and spectroscopic data on GCs in NGC 5128 (Cen A) and NGC 4594 (Sombrero), we investigate the nonlinearity of GC CMRs and compare the observed GC CMRs with the predictions of stellar population simulation models. Our careful selection of old GCs effectively reduces the scatter and reveals the nonlinear nature of the GC CMRs for various colors. The overall shape of the observed CMRs agrees well with that of the modeled CMRs, while offsets are present for some colors. We discuss the implications of our results in terms of the GC color bimodality and GC formation in NGC 5128 and NGC 4594.

• 천문학회보
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• 제40권2호
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• pp.40.2-40.2
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• 2015

In our recent investigation (Lim et al. 2015), we have shown that the combination of narrow-band Ca photometry and low-resolution spectroscopy can effectively search for globular clusters (GCs) with supernovae (SNe) enrichments. We apply this technique to the metal-poor bulge GC NGC 6273 and find two distinct subpopulations having different light and heavy element abundances. Our result suggests that NGC 6273 was massive enough to retain SNe ejecta, which would place this cluster in the growing group of GCs with Galactic building block characteristics, such as ${\omega}$ Centauri and M22.

• 천문학회보
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• 제38권2호
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• pp.79.2-79.2
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• 2013

The distributions of Horizontal Branch (HB) star color, temperature, and mass encode a great deal of information on the stellar evolutionary and (possibly) dynamical processes taking place in Globular Clusters (GCs). An accurate physical modeling of the Red Giant Branch (RGB) mass-loss process is key to solving the so-called second parameter problem. In my poster I will present the most recent advancements of an analytical model for mass-loss along the RGB. The model predicts the HB mass distribution with remarkable accuracy over a sample of 4 GCs. These results were submitted as a paper to ApJ (Pasquato et al. 2013, ApJ submitted), but here I expand on them presenting refinements to the model and a comparison with HB masses obtained from Galex ultraviolet observations.

• 천문학회보
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• 제35권2호
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• pp.82.2-82.2
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• 2010

We investigate the distribution of stars along the red giant branch (RGB) in the globular clusters (GCs) NGC 288 and NGC 362 from Caby photometry using the CTIO 4m Blanco telescope. Our color-magnitude diagrams in hk index show that the RGB stars have two distinct subpopulations with different Ca abundances apparently supplied by the Type II supernovae explosions. However, the RGB splits are not shown in the b - y color, as indicated by previous observations. Our stellar population models show that the presence of two distinct RGBs in these GCs can be reproduced if metal-rich second generation stars are also enhanced in helium and younger by 1 ~ 2 Gyrs.

• 대한임상독성학회지
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• 제5권1호
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• pp.8-14
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• 2007

Purpose: Organophosphorus insecticides tend to be regarded as a homogeneous single entity. We aimed to determine whether organophosphate poisoning differs by subgroups in clinical features and severity. Methods: We retrospectively reviewed medical records of all patients with acute organophophorus poisoning from January 1998 to December 2006. We investigated clinical features, Glasgow coma scale (GCS), laboratory findings, QTc intervals, management, and outcomes. Results: A total of 109 patients were included. The dimethoxy group experienced significantly longer times than the diethoxy group for ventilation duration (0.6 day vs. 0.2 day, p=0.006), ICU duration (2.0 day vs. 0.8 day, p=0.037), and total admission duration (2.8 day vs. 0.9 day, p=0.008), except in cases of dichlorvos poisoning. Also, the GCS of the dimethoxy group (except with dichlorvos) was significantly lower than for the diethoxy group (dimethoxy, $11.2{\pm}5.2$ vs. diethoxy, $13.8{\pm}2.4$, p= 0.021). QTc intervals for the dimethoxy group (except with dichlorvos) tended to be somewhat greater than for the diethoxy group (dimethoxy, $452.9{\pm}16.1\;msec$ vs. diethoxy, $429.6{\pm}40.9\;msec$). There were 65 patients with dichlorvos ingestion, and 2 of these patients (3%) died. Conclusion: When compared to the diethoxy group, the dimethoxy group of organophosphates (with the exception of dichlorvos) were associated with poorer prognostic value for indicators such as GCS, QTc interval, requirement for intubation, ICU duration, and total admission duration. Within the dimethoxy group, patients with dichlorvos poisoning had relatively better prognoses than for the other dimethoxy group organophosphates studied.

• 대한임상독성학회지
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• 제9권2호
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• pp.49-55
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• 2011

Purpose: Acetanilide has been in widespread use as an amide herbicide compound. However, available data regarding acute human poisoning is scarce. The aim of this study was to analyze the clinical characteristics of acetanilide poisoning in order to identify the risk factors associated with severity. Methods: We conducted a retrospective observational study encompassing the period January 2005 to December 2010, including adult ED patients suffering from acetanilide intoxication. Toxicological history, symptoms observed, clinical signs of toxicity, and laboratory test results were collected for each patient. The patients were classified into two groups for analysis, according their poisoning severity score (PSS). Resulting clinical data and prognostic variables were compared between mild-to-moderate poisoning (PSS 1/2 grades), and severe poisonings and fatalities (PSS 3/4 grades). Results: There were a total of 37 patients, including 26 alachlor, 6 s-metolachlor, 4 mefenacet, and 1 butachlor cases. The majority of patients (81.1%) were assigned PSS 1/2 grades. Changes in mental status and observation of adverse neurologic symptoms were more common in the PSS 3/4 group. The median ingested volume of amide herbicide compound was 250 ml (IQR 200-300 ml) in the PSS 3/4 group, and 80 ml (IQR 50-138 ml) in the PSS 1/2 group. Also, the median GCS observed in the PSS 3/4 group was 13 (IQR 10-14), which was markedly low as compared to a median GCS of 15 in the PSS 1/2 group. Overall mortality rate was 5.4%, and profound cardiogenic shock was observed prior to death in all fatalities. Conclusion: When compared to previous reports, acute acetanilide poisoning resulted in relatively moderate severity. The presence of neurologic manifestations, hypotension, lower GCS score, and larger ingested volumes was associated with more serious effects and mortalities.